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gamma-aminobutyric acid and Myopia

gamma-aminobutyric acid has been researched along with Myopia in 7 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Myopia: A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.

Research Excerpts

ExcerptRelevanceReference
"Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter of the retina and affects myopic development."5.42Effects of electroacupuncture on the levels of retinal gamma-aminobutyric acid and its receptors in a guinea pig model of lens-induced myopia. ( Bi, AL; Bi, HS; Ding, MH; Guo, DD; Guo, JG; Jiang, WJ; Sha, F; Wang, L; Wu, JF; Xu, CL; Ye, X; Zhao, W, 2015)
"A single, large dose of N-methyl-D-aspartate (NMDA) or quisqualic acid (QA) injected into the chick eye has been shown previously to destroy many retinal amacrine cells and to induce excessive ocular growth accompanied by myopia."3.70Immunocytochemical characterization of quisqualic acid- and N-methyl-D-aspartate-induced excitotoxicity in the retina of chicks. ( Fischer, AJ; Poon, J; Seltner, RL; Stell, WK, 1998)
"When added to a standardized postoperative pain regimen, gabapentin use led to no additional improvement in PRK pain control compared with a placebo at the dose and the time intervals tested."2.76Oral gabapentin for photorefractive keratectomy pain. ( Bower, KS; Coe, CD; Eaddy, J; Edwards, J; Howard, RS; Kuhnle, MD; Kuzmowych, C; Ryan, DS, 2011)
"Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter of the retina and affects myopic development."1.42Effects of electroacupuncture on the levels of retinal gamma-aminobutyric acid and its receptors in a guinea pig model of lens-induced myopia. ( Bi, AL; Bi, HS; Ding, MH; Guo, DD; Guo, JG; Jiang, WJ; Sha, F; Wang, L; Wu, JF; Xu, CL; Ye, X; Zhao, W, 2015)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's4 (57.14)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Wei, P1
Han, G1
He, M1
Wang, Y1
Sha, F1
Ye, X2
Zhao, W2
Xu, CL2
Wang, L1
Ding, MH1
Bi, AL2
Wu, JF1
Jiang, WJ2
Guo, DD1
Guo, JG2
Bi, HS2
Chen, MQ1
Wang, XT1
Zhang, XY1
Zhang, J1
Guoping, L1
Xiang, Y1
Jianfeng, W1
Dadong, G1
Jie, H1
Wenjun, J1
Junguo, G1
Hongsheng, B1
Kuhnle, MD1
Ryan, DS1
Coe, CD1
Eaddy, J1
Kuzmowych, C1
Edwards, J1
Howard, RS1
Bower, KS1
Stone, RA1
Liu, J1
Sugimoto, R1
Capehart, C1
Zhu, X1
Pendrak, K1
Fischer, AJ1
Seltner, RL1
Poon, J1
Stell, WK1

Trials

1 trial available for gamma-aminobutyric acid and Myopia

ArticleYear
Oral gabapentin for photorefractive keratectomy pain.
    Journal of cataract and refractive surgery, 2011, Volume: 37, Issue:2

    Topics: Acetaminophen; Administration, Oral; Adult; Amines; Analgesics; Astigmatism; Cyclohexanecarboxylic A

2011

Other Studies

6 other studies available for gamma-aminobutyric acid and Myopia

ArticleYear
Retinal Neurotransmitter Alteration in Response to Dopamine D2 Receptor Antagonist from Myopic Guinea Pigs.
    ACS chemical neuroscience, 2023, 09-20, Volume: 14, Issue:18

    Topics: Animals; Dopamine D2 Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Guinea P

2023
Effects of electroacupuncture on the levels of retinal gamma-aminobutyric acid and its receptors in a guinea pig model of lens-induced myopia.
    Neuroscience, 2015, Feb-26, Volume: 287

    Topics: Animals; Electroacupuncture; gamma-Aminobutyric Acid; Guinea Pigs; Myopia; Receptors, GABA; Retina;

2015
GABA and GABA receptors alterations in the primary visual cortex of concave lens-induced myopic model.
    Brain research bulletin, 2017, Volume: 130

    Topics: Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Guinea Pigs; Male

2017
Alterations of Glutamate and γ-Aminobutyric Acid Expressions in Normal and Myopic Eye Development in Guinea Pigs.
    Investigative ophthalmology & visual science, 2017, 02-01, Volume: 58, Issue:2

    Topics: Analysis of Variance; Animals; Axial Length, Eye; Chromatography, High Pressure Liquid; Disease Mode

2017
GABA, experimental myopia, and ocular growth in chick.
    Investigative ophthalmology & visual science, 2003, Volume: 44, Issue:9

    Topics: Animals; Chickens; Disease Models, Animal; Eye; GABA Agonists; GABA Antagonists; GABA-A Receptor Ago

2003
Immunocytochemical characterization of quisqualic acid- and N-methyl-D-aspartate-induced excitotoxicity in the retina of chicks.
    The Journal of comparative neurology, 1998, Mar-30, Volume: 393, Issue:1

    Topics: Animals; Antibody Specificity; Biomarkers; Carrier Proteins; Chickens; Choline O-Acetyltransferase;

1998