Page last updated: 2024-10-16

gamma-aminobutyric acid and Myalgia

gamma-aminobutyric acid has been researched along with Myalgia in 3 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Myalgia: Painful sensation in the muscles.

Research Excerpts

ExcerptRelevanceReference
"In the present work, we investigated the antinociceptive effect of gabapentin in a chronic myositis model and its interference in spinal glial cells."7.85Gabapentin decreases microglial cells and reverses bilateral hyperalgesia and allodynia in rats with chronic myositis. ( Chacur, M; Freitas, MF; Rocha, IR; Rosa, AS, 2017)
"Chronic myositis was induced by injection of Complete Freund Adjuvant (CFA) into the right gastrocnemius (GS) muscle of rats and tests for evaluating mechanical hyperalgesia, thermal hyperalgesia and tactile allodynia were performed."5.46Gabapentin decreases microglial cells and reverses bilateral hyperalgesia and allodynia in rats with chronic myositis. ( Chacur, M; Freitas, MF; Rocha, IR; Rosa, AS, 2017)
" Lorazepam, a positive allosteric modulator of the GABAA-receptor, was co-injected with GABA in both studies to explore the role of this receptor in muscle pain responses of healthy human volunteers."3.91The pro-algesic effect of γ-aminobutyric acid (GABA) injection into the masseter muscle of healthy men and women. ( Arendt-Nielsen, L; Cairns, BE; Liao, S; Meijs, S; Wang, K, 2019)
"In the present work, we investigated the antinociceptive effect of gabapentin in a chronic myositis model and its interference in spinal glial cells."3.85Gabapentin decreases microglial cells and reverses bilateral hyperalgesia and allodynia in rats with chronic myositis. ( Chacur, M; Freitas, MF; Rocha, IR; Rosa, AS, 2017)
"Chronic myositis was induced by injection of Complete Freund Adjuvant (CFA) into the right gastrocnemius (GS) muscle of rats and tests for evaluating mechanical hyperalgesia, thermal hyperalgesia and tactile allodynia were performed."1.46Gabapentin decreases microglial cells and reverses bilateral hyperalgesia and allodynia in rats with chronic myositis. ( Chacur, M; Freitas, MF; Rocha, IR; Rosa, AS, 2017)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Meijs, S1
Liao, S1
Arendt-Nielsen, L1
Wang, K1
Cairns, BE1
Haviv, Y1
Rettman, A1
Aframian, D1
Sharav, Y1
Benoliel, R1
Rosa, AS1
Freitas, MF1
Rocha, IR1
Chacur, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Side Effects of Two Different Mandibular Advancement Devices (MAD) in the Treatment of Snoring and Obstructive Sleep Apnea Syndrome (OSAS)[NCT04050514]65 participants (Actual)Interventional2019-12-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for gamma-aminobutyric acid and Myalgia

ArticleYear
Myofascial pain: an open study on the pharmacotherapeutic response to stepped treatment with tricyclic antidepressants and gabapentin.
    Journal of oral & facial pain and headache, 2015,Spring, Volume: 29, Issue:2

    Topics: Adult; Age Factors; Amines; Amitriptyline; Antidepressive Agents, Tricyclic; Comorbidity; Cyclohexan

2015

Other Studies

2 other studies available for gamma-aminobutyric acid and Myalgia

ArticleYear
The pro-algesic effect of γ-aminobutyric acid (GABA) injection into the masseter muscle of healthy men and women.
    Scandinavian journal of pain, 2019, 12-18, Volume: 20, Issue:1

    Topics: Adult; Analgesics; Female; GABA Agents; gamma-Aminobutyric Acid; Glutamic Acid; Healthy Volunteers;

2019
Gabapentin decreases microglial cells and reverses bilateral hyperalgesia and allodynia in rats with chronic myositis.
    European journal of pharmacology, 2017, Mar-15, Volume: 799

    Topics: Amines; Animals; Astrocytes; Behavior, Animal; Cell Count; Chronic Disease; Cyclohexanecarboxylic Ac

2017