gamma-aminobutyric acid has been researched along with Muscle Spasm in 24 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe the case of an 82 year old woman developing severe respiratory functional impairment after open heart surgery and subsequent surgical pericardial drainage inducing diaphragmatic spasm and successfully treated with gabapentin." | 7.73 | Post cardiac surgery diaphragmatic spasm successfully treated with gabapentin. ( Amadio, S; Corti, A; Fragasso, G; Garroni, D; Margonato, A; Montano, C; Palloshi, A; Spoladore, R, 2006) |
| "We conducted an open-label trial of gabapentin (GBP) as therapy for paroxysmal symptoms (PS) in 21 MS patients, including trigeminal neuralgia (6 patients), painful tonic spasms (11), dysesthetic or paresthetic symptoms (3) and ocular ataxia (1)." | 7.70 | An open-label trial of gabapentin treatment of paroxysmal symptoms in multiple sclerosis patients. ( Capello, E; Inglese, M; Lunardi, GL; Mancardi, GL; Messmer Uccelli, M; Solaro, C; Uccelli, A, 1998) |
| "Gabapentin is a novel antiepileptic drug that is generally well tolerated." | 5.29 | Gabapentin for the treatment of hemifacial spasm. ( Naritoku, DK; Patel, J, 1996) |
| "We describe the case of an 82 year old woman developing severe respiratory functional impairment after open heart surgery and subsequent surgical pericardial drainage inducing diaphragmatic spasm and successfully treated with gabapentin." | 3.73 | Post cardiac surgery diaphragmatic spasm successfully treated with gabapentin. ( Amadio, S; Corti, A; Fragasso, G; Garroni, D; Margonato, A; Montano, C; Palloshi, A; Spoladore, R, 2006) |
| "We conducted an open-label trial of gabapentin (GBP) as therapy for paroxysmal symptoms (PS) in 21 MS patients, including trigeminal neuralgia (6 patients), painful tonic spasms (11), dysesthetic or paresthetic symptoms (3) and ocular ataxia (1)." | 3.70 | An open-label trial of gabapentin treatment of paroxysmal symptoms in multiple sclerosis patients. ( Capello, E; Inglese, M; Lunardi, GL; Mancardi, GL; Messmer Uccelli, M; Solaro, C; Uccelli, A, 1998) |
| "The medicinal treatment of spasticity includes use of oral treatments (baclofène and tizanidine), botulinum toxin, intrathecal baclofène and local application of alcohol or phenol." | 2.48 | [Pharmacological treatment of spasticity in multiple sclerosis]. ( Heinzlef, O; Monteil-Roch, I, 2012) |
| "It is characterized by muscle spasms triggered by startle, voluntary movement, or tactile or emotional stimuli, occurring predominantly in the axial musculature." | 1.37 | Stiff person syndrome and pregnancy. ( Blaskiewicz, R; Goldkamp, J; Myles, T, 2011) |
| "We report the successful management of anesthesia in a patient with stiff-person syndrome (SPS) undergoing a thymectomy using a volatile anesthetic combined with epidural anesthesia." | 1.34 | Considerations for general anesthesia combined with epidural anesthesia in a patient with stiff-person syndrome. ( Hara, K; Horishita, T; Sata, T; Yamamoto, K, 2007) |
| "GBP increases the risk of myoclonus in ESRD." | 1.33 | Gabapentin-induced myoclonus in end-stage renal disease. ( Bell, WL; Glenn, DG; O'Donovan, CA; Zhang, C, 2005) |
| "Three of 71 patients had myoclonus with GBP doses ranging from 9 mg/kg to 20 mg/kg and within 4 months of treatment onset." | 1.33 | Gabapentin-induced myoclonus in end-stage renal disease. ( Bell, WL; Glenn, DG; O'Donovan, CA; Zhang, C, 2005) |
| "Myoclonus was characterized as multifocal, involving all extremities in the three patients." | 1.33 | Gabapentin-induced myoclonus in end-stage renal disease. ( Bell, WL; Glenn, DG; O'Donovan, CA; Zhang, C, 2005) |
| "Gabapentin thus appears to be an effective treatment for Isaacs' syndrome." | 1.33 | Isaacs' syndrome: clinical and electrophysiological response to gabapentin. ( Dhand, UK, 2006) |
| "A patient with Isaacs' syndrome had generalized muscle spasms, twitching, and progressive muscle stiffness for 21 years." | 1.33 | Isaacs' syndrome: clinical and electrophysiological response to gabapentin. ( Dhand, UK, 2006) |
| "Gabapentin is a novel antiepileptic drug that is generally well tolerated." | 1.29 | Gabapentin for the treatment of hemifacial spasm. ( Naritoku, DK; Patel, J, 1996) |
| "Stiff-man syndrome is a rare disorder of the central nervous system consisting of progressive, fluctuating muscle rigidity with painful spasms." | 1.27 | Autoantibodies to glutamic acid decarboxylase in a patient with stiff-man syndrome, epilepsy, and type I diabetes mellitus. ( Comi, GC; De Camilli, P; Denis-Donini, S; Folli, F; Pozza, G; Solimena, M; Vicari, AM, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (25.00) | 18.7374 |
| 1990's | 3 (12.50) | 18.2507 |
| 2000's | 7 (29.17) | 29.6817 |
| 2010's | 7 (29.17) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Taneda, T | 1 |
| Okawara, S | 1 |
| Namekawa, M | 1 |
| Umeda, Y | 1 |
| Oyake, M | 1 |
| Fujita, N | 1 |
| Mari, Z | 1 |
| Rosenthal, LS | 1 |
| Darwin, KC | 1 |
| Hallett, M | 1 |
| Jinnah, HA | 1 |
| Dayalu, P | 1 |
| Teener, JW | 1 |
| Kalaci, A | 1 |
| Duru, M | 1 |
| Karazincir, S | 1 |
| Sevinç, TT | 1 |
| Kuvandik, G | 1 |
| Balci, A | 1 |
| Schleich, A | 1 |
| Baumann, H | 1 |
| Ali, F | 1 |
| Rowley, M | 1 |
| Jayakrishnan, B | 1 |
| Teuber, S | 1 |
| Gershwin, ME | 1 |
| Mackay, IR | 1 |
| Goldkamp, J | 1 |
| Blaskiewicz, R | 1 |
| Myles, T | 1 |
| Singh, H | 1 |
| Wang, MY | 1 |
| Heinzlef, O | 1 |
| Monteil-Roch, I | 1 |
| Zhang, C | 1 |
| Glenn, DG | 1 |
| Bell, WL | 1 |
| O'Donovan, CA | 1 |
| Spoladore, R | 1 |
| Garroni, D | 1 |
| Fragasso, G | 1 |
| Palloshi, A | 1 |
| Amadio, S | 1 |
| Montano, C | 1 |
| Corti, A | 1 |
| Margonato, A | 1 |
| Dhand, UK | 1 |
| Yamamoto, K | 1 |
| Hara, K | 1 |
| Horishita, T | 1 |
| Sata, T | 1 |
| Dalakas, MC | 1 |
| Patel, J | 1 |
| Naritoku, DK | 1 |
| Solaro, C | 2 |
| Lunardi, GL | 1 |
| Capello, E | 1 |
| Inglese, M | 1 |
| Messmer Uccelli, M | 1 |
| Uccelli, A | 2 |
| Mancardi, GL | 2 |
| Uccelli, MM | 1 |
| Guglieri, P | 1 |
| Levine, IM | 1 |
| Jossmann, PB | 1 |
| DeAngelis, V | 1 |
| Solimena, M | 2 |
| Folli, F | 2 |
| Aparisi, R | 1 |
| Pozza, G | 2 |
| De Camilli, P | 2 |
| Denis-Donini, S | 1 |
| Comi, GC | 1 |
| Vicari, AM | 1 |
| Basmajian, JV | 1 |
| Yucel, V | 1 |
| Shahani, BT | 1 |
| Young, RR | 1 |
| Pedersen, E | 1 |
| Arlien-Soborg, P | 1 |
| Mai, J | 1 |
| Truelle, JL | 1 |
| Pelier-Cady, MC | 1 |
| Chanelet, J | 1 |
| Emile, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Efficacy of High-Dose Intravenous Immunoglobulin Therapy in Patients With Stiff-Man Syndrome: A Double-Blind, Placebo-Controlled Trial[NCT00001550] | Phase 1 | 20 participants | Interventional | 1996-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for gamma-aminobutyric acid and Muscle Spasm
| Article | Year |
|---|---|
Clinical Reasoning: a 57-year-old man with jaw spasms.
Topics: Adrenergic Uptake Inhibitors; Amines; Anticonvulsants; Brain Neoplasms; Cyclohexanecarboxylic Acids; | 2013 |
Stiff Person syndrome and other anti-GAD-associated neurologic disorders.
Topics: Autoantibodies; Central Nervous System; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hu | 2012 |
Stiff-person syndrome (SPS) and anti-GAD-related CNS degenerations: protean additions to the autoimmune central neuropathies.
Topics: Autoantibodies; Central Nervous System; Diabetes Mellitus, Type 1; Epilepsy; GABAergic Neurons; gamm | 2011 |
Gabapentin reduces experimental secondary neurologic dysfunction in rats.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Nervous S | 2011 |
[Pharmacological treatment of spasticity in multiple sclerosis].
Topics: Algorithms; Amines; Baclofen; Botulinum Toxins, Type A; Clonidine; Cyclohexanecarboxylic Acids; Dant | 2012 |
Advances in the pathogenesis and treatment of patients with stiff person syndrome.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis Regulatory Proteins; Autoantibodies; Autoantigens; C | 2008 |
4 trials available for gamma-aminobutyric acid and Muscle Spasm
| Article | Year |
|---|---|
Gabapentin is effective in treating nocturnal painful spasms in multiple sclerosis.
Topics: Acetates; Amines; Anticonvulsants; Circadian Rhythm; Cyclohexanecarboxylic Acids; Gabapentin; gamma- | 2000 |
Liorseal, a new muscle relaxant in the treatment of spasticity--a double-blind quantitative evaluation.
Topics: Adult; Aminobutyrates; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Meth | 1977 |
Effects of a GABA--derivative (BA-34647) on spasticity. Preliminary report of a double-blind cross-over study.
Topics: Administration, Oral; Adult; Aminobutyrates; Clinical Trials as Topic; Electromyography; Female; gam | 1974 |
[New treatments of spasticity (pyramidal hypertonia)].
Topics: Aminobutyrates; Clinical Trials as Topic; gamma-Aminobutyric Acid; Humans; Muscle Proteins; Pyramida | 1974 |
14 other studies available for gamma-aminobutyric acid and Muscle Spasm
| Article | Year |
|---|---|
[Isolated ACTH deficiency clinically presented as stiff-person syndrome, successfully treated by hormonal replacement: a case report].
Topics: Adrenocorticotropic Hormone; Aged; Aminobutyrates; Autoantibodies; Contracture; Endocrine System Dis | 2022 |
Thoracic spine compression fracture during isoniazid-induced seizures: case report.
Topics: Antidotes; Back Pain; Charcoal; Child; Drug Overdose; Epilepsy, Tonic-Clonic; Female; Fractures, Com | 2008 |
[Disease with generalized pain. Guillain-Barré syndrome].
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Gabapentin; | 2011 |
Stiff person syndrome and pregnancy.
Topics: Adult; Amines; Baclofen; Cesarean Section; Cyclohexanecarboxylic Acids; Diazepam; Female; Gabapentin | 2011 |
Gabapentin-induced myoclonus in end-stage renal disease.
Topics: Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric | 2005 |
Post cardiac surgery diaphragmatic spasm successfully treated with gabapentin.
Topics: Aged, 80 and over; Amines; Anti-Anxiety Agents; Aortic Valve Stenosis; Cyclohexanecarboxylic Acids; | 2006 |
Isaacs' syndrome: clinical and electrophysiological response to gabapentin.
Topics: Action Potentials; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Electromyogr | 2006 |
Considerations for general anesthesia combined with epidural anesthesia in a patient with stiff-person syndrome.
Topics: Aged; Anesthesia, Epidural; Anesthesia, General; gamma-Aminobutyric Acid; Humans; Male; Muscle Rigid | 2007 |
Gabapentin for the treatment of hemifacial spasm.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Facial Nerve Diseases; Female; Gabap | 1996 |
An open-label trial of gabapentin treatment of paroxysmal symptoms in multiple sclerosis patients.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Ami | 1998 |
Autoantibodies to GABA-ergic neurons and pancreatic beta cells in stiff-man syndrome.
Topics: Autoantibodies; Autoantigens; Autoimmune Diseases; Brain; Central Nervous System Diseases; Cerebrosp | 1990 |
Autoantibodies to glutamic acid decarboxylase in a patient with stiff-man syndrome, epilepsy, and type I diabetes mellitus.
Topics: Autoantibodies; Autoimmune Diseases; Brain; Diabetes Mellitus, Type 1; Epilepsy; Female; gamma-Amino | 1988 |
Management of flexor spasms with Lioresal.
Topics: Administration, Oral; Adult; Chlorobenzenes; Drug Evaluation; Electromyography; Evoked Potentials; F | 1974 |
The mode of action of the gaba derivative baclofen in human spasticy.
Topics: Achilles Tendon; Aminobutyrates; Depression, Chemical; gamma-Aminobutyric Acid; Humans; Multiple Scl | 1974 |