Page last updated: 2024-10-16

gamma-aminobutyric acid and Muscle Relaxation

gamma-aminobutyric acid has been researched along with Muscle Relaxation in 62 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
"The effect of hyperhomocysteinemia induced by pretreatment with methionine 12 weeks prior to the study on the responses induced by gamma-aminobutyric acid (GABA), electrical field stimulation (EFS), and ATP have been evaluated in isolated rat duodenum."7.74Effects of hyperhomocysteinemia on non-adrenergic non-cholinergic relaxation in isolated rat duodenum. ( Karasu, E; Sadan, G; Tasatargil, A, 2008)
"The effect of hyperhomocysteinemia induced by pretreatment with methionine 12 weeks prior to the study on the responses induced by gamma-aminobutyric acid (GABA), electrical field stimulation (EFS), and ATP have been evaluated in isolated rat duodenum."3.74Effects of hyperhomocysteinemia on non-adrenergic non-cholinergic relaxation in isolated rat duodenum. ( Karasu, E; Sadan, G; Tasatargil, A, 2008)
"The effects of three specific GABA receptor agonists, muscimol, progabide, and gaboxadol, on kindled seizures were evaluated in amygdala-kindled rats."3.67Evaluation of different GABA receptor agonists in the kindled amygdala seizure model in rats. ( Löscher, W; Schwark, WS, 1985)
"Pretreatment with bicuculline (GABAA antagonist) turned them to relaxation."2.67gamma-Aminobutyric acid enhances the tone of human internal anal sphincter. ( Fujita, S; Kusunoki, M; Sakanoue, Y; Shoji, Y; Utsunomiya, J; Yamamura, T; Yanagi, H, 1991)
"Muscle relaxation is not feasible in principle, although muscle contraction can be easily induced by electrical stimulation."1.48Neurotransmitter-Loaded Nanocapsule Triggers On-Demand Muscle Relaxation in Living Organism. ( Arai, S; Le, DL; Sato, H; Sou, K; Suzuki, M; Tnee, CK; Vo Doan, TT, 2018)
" None of the K+ channel blockers had an effect on the dose-response curve to NO, on the noradrenaline-induced contraction or on the relaxation to nitroglycerine (GTN)."1.29Prejunctional modulation of the nitrergic innervation of the canine ileocolonic junction via potassium channels. ( Boeckxstaens, GE; De Man, JG; De Winter, BY; Herman, AG; Pelckmans, PP; Van Maercke, YM, 1993)
"The baclofen response was antagonized by 5-aminovaleric acid (DAVA, 500 microM), TTX and hyoscine and resistant to GABAA-receptor and adrenoceptor blockade."1.28An in vitro study of the relationship between GABA receptor function and propulsive motility in the distal colon of the rabbit. ( Candura, SM; Crema, A; Frigo, GM; Manzo, L; Onori, L; Rizzi, CA; Tonini, M, 1989)
"Buspirone is a clinically effective anxiolytic with a unique structure and pharmacology which distinguishes it from the benzodiazepines."1.27Neuropharmacology of buspirone. ( Eison, AS; Eison, MS; Riblet, LA; Taylor, DP; Temple, DL; VanderMaelen, CP, 1984)
"Muscimol and gaboxadol were almost inactive in attenuating kindled seizures even at doses that produced pronounced side effects."1.27Evaluation of different GABA receptor agonists in the kindled amygdala seizure model in rats. ( Löscher, W; Schwark, WS, 1985)
"A decrease in severity of motor seizures was found only after 200 mg/kg progabide which, however, gave rise to marked sedation and muscle relaxation."1.27Evaluation of different GABA receptor agonists in the kindled amygdala seizure model in rats. ( Löscher, W; Schwark, WS, 1985)
" The dose-response curve of ifenprodil tartrate was shifted to the left by pre-incubation in calcium hopantenate."1.27A possible mechanism on the potentiating vascular effect of coadministration of ifenprodil tartrate and calcium hopantenate: a study in the internal carotid artery. ( Honda, H; Irino, O; Iwata, T; Izumisawa, M; Matsuda, H; Shibuya, T; Shimura, H; Tsuji, H; Watanabe, Y, 1988)
"suum muscle contraction is mediated by actin."1.27Ascaris suum: regulation of myosin light chain phosphorylation from adult skeletal muscle. ( Donahue, MJ; Martin, RE; Masaracchia, RA, 1986)
" The i--response counteracts the inhibitory effect of GABA at low GABA concentrations and can distort the dose-response curve."1.26Closing of membrane channels effected by gamma-amino-butyric acid (GABA) in crayfish muscle. ( Dudel, J; Finger, W, 1980)

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-199025 (40.32)18.7374
1990's21 (33.87)18.2507
2000's11 (17.74)29.6817
2010's5 (8.06)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Le, DL1
Tnee, CK1
Vo Doan, TT1
Arai, S1
Suzuki, M1
Sou, K1
Sato, H1
Karasu, E1
Sadan, G2
Tasatargil, A1
Liewald, JF1
Brauner, M1
Stephens, GJ1
Bouhours, M1
Schultheis, C1
Zhen, M1
Gottschalk, A1
Samanta, SK1
Kumar, KT1
Roy, A1
Karmakar, S1
Lahiri, S1
Palit, G1
Vedasiromoni, JR1
Sen, T2
Gallos, G2
Gleason, NR1
Virag, L2
Zhang, Y2
Mizuta, K1
Whittington, RA1
Emala, CW2
Rotondo, A1
Serio, R1
Mulè, F1
Kullyev, A1
Dempsey, CM1
Miller, S1
Kuan, CJ1
Hapiak, VM1
Komuniecki, RW1
Griffin, CT1
Sze, JY1
Kurjak, M1
Fichna, J1
Harbarth, J1
Sennefelder, A1
Allescher, HD1
Schusdziarra, V1
Storr, M1
Otto, B1
Townsend, E1
Yim, P1
Xu, D1
Bacchetta, M1
Lehmann, A2
Bremner-Danielsen, M1
Brändén, L1
Kärrberg, L1
Haxhiu, MA1
Yamamoto, BK1
Dreshaj, IA1
Ferguson, DG1
Park, SY1
Shin, CY1
Song, HJ1
Min, YS1
La Hyen, O1
Lee, JW1
Kim, DY1
Je, HD1
Sohn, UD1
Hamrouni, AM1
Gudka, N1
Broadley, KJ1
Popik, P1
Kostakis, E1
Krawczyk, M1
Nowak, G1
Szewczyk, B1
Krieter, P1
Chen, Z1
Russek, SJ1
Gibbs, TT1
Farb, DH1
Skolnick, P3
Lippa, AS1
Basile, AS1
Yoon, BH1
Jung, JW1
Lee, JJ1
Cho, YW1
Jang, CG1
Jin, C1
Oh, TH1
Ryu, JH1
Maggi, CA4
Manzini, S3
Meli, A4
Tallman, JF1
Paul, SM2
Gallager, DW1
Riblet, LA1
Eison, AS1
Eison, MS1
Taylor, DP1
Temple, DL1
VanderMaelen, CP1
Heizmann, CW1
Dudel, J2
Finger, W2
Fukushi, Y1
Suzuki, T1
Anwar, N1
Mason, DF1
Biscoe, TJ1
Fry, JP1
Stettmeier, H1
Patti, F1
Maccagnano, C1
Panico, AM1
Giammona, G1
Rampello, L1
Reggio, A1
Di Giorgio, RM1
Nicoletti, F1
Reiner, DJ1
Thomas, JH1
Grider, JR1
Franks, CJ1
Holden-Dye, L1
Williams, RG1
Pang, FY1
Walker, RJ1
Pencheva, N2
Radomirov, R2
De Man, JG2
Boeckxstaens, GE2
Pelckmans, PP1
De Winter, BY1
Herman, AG2
Van Maercke, YM2
Guo, LJ1
Qu, L1
Lee, TJ1
Krantis, A2
Mattar, K1
Glasgow, I1
Kogo, M1
Tanaka, S1
Chandler, SH1
Matsuya, T1
Pal, S1
Chaudhuri, AK2
Kilbinger, H1
Ginap, T1
Erbelding, D1
Kaputlu, I1
Ozdem, S1
Gökalp, O1
Blackshaw, LA1
Staunton, E1
Dent, J1
Correia, NA1
Cavalcanti, PM1
Oliveira, RB1
Ballejo, G1
Rhyu, MR1
Kim, DK1
Kim, HY1
Kim, BK1
Snyder, SH1
Enna, SJ1
Young, AB1
Naik, SR1
Naid, PR1
Sheth, UK1
Habibuddin, M1
Pal, M2
Pal, SP2
Irie, K1
Muraki, T1
Furukawa, K1
Nomoto, T1
Kusunoki, M1
Shoji, Y1
Sakanoue, Y1
Yanagi, H1
Fujita, S1
Yamamura, T1
Utsunomiya, J1
Pelckmans, PA1
Bult, H1
Dutta, AS1
Stefański, R1
Plaznik, A1
Pałejko, W1
Kostowski, W1
Khalil, A1
McKay, A1
Lai, FM1
Tanikella, T1
Cervoni, P1
Robertson, B1
Giuliani, S1
Santicioli, P1
Selleri, S1
Tonini, M1
Crema, A1
Frigo, GM1
Rizzi, CA1
Manzo, L1
Candura, SM1
Onori, L1
Bhowmick, S1
Stahmer, SD1
Löscher, W1
Schwark, WS1
Ong, J1
Kerr, DI1
Shibuya, T1
Honda, H1
Watanabe, Y1
Shimura, H1
Matsuda, H1
Tsuji, H1
Izumisawa, M1
Iwata, T1
Irino, O1
Martin, RE1
Masaracchia, RA1
Donahue, MJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Perceived Changes in Anxiety Symptom Burden During Treatment With Bryophyllum Pinnatum and Tolerability: a Prospective, Single-Group Pre-post Observational Study as Investigator-Initiated Trial (IIT)[NCT04825171]Phase 451 participants (Anticipated)Interventional2021-08-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for gamma-aminobutyric acid and Muscle Relaxation

ArticleYear
Receptors for the age of anxiety: pharmacology of the benzodiazepines.
    Science (New York, N.Y.), 1980, Jan-18, Volume: 207, Issue:4428

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Benzodiazepines; Brain; gamma-Aminobutyric A

1980
The mechanism(s) of action of the benzodiazepines.
    Medicinal research reviews, 1981,Spring, Volume: 1, Issue:1

    Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Caffeine; Carbolines; C

1981
Parvalbumin, an intracellular calcium-binding protein; distribution, properties and possible roles in mammalian cells.
    Experientia, 1984, Sep-15, Volume: 40, Issue:9

    Topics: Adenosine Triphosphatases; Amino Acid Sequence; Amino Acids; Animals; Brain; Calcium; Chemical Pheno

1984
Pharmacodynamics of benzodiazepines.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1985, Oct-26, Volume: Suppl

    Topics: Aggression; Animals; Anti-Anxiety Agents; Anxiety; Astrocytes; Autonomic Nervous System; Behavior; B

1985

Trials

1 trial available for gamma-aminobutyric acid and Muscle Relaxation

ArticleYear
gamma-Aminobutyric acid enhances the tone of human internal anal sphincter.
    The Journal of surgical research, 1991, Volume: 51, Issue:4

    Topics: Anal Canal; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Humans; Muscimol; Muscle Contraction; Mu

1991

Other Studies

57 other studies available for gamma-aminobutyric acid and Muscle Relaxation

ArticleYear
Neurotransmitter-Loaded Nanocapsule Triggers On-Demand Muscle Relaxation in Living Organism.
    ACS applied materials & interfaces, 2018, Nov-07, Volume: 10, Issue:44

    Topics: Animals; Coleoptera; Drug Carriers; Electric Stimulation; gamma-Aminobutyric Acid; Humans; Liposomes

2018
Effects of hyperhomocysteinemia on non-adrenergic non-cholinergic relaxation in isolated rat duodenum.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:8

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Disease Models, Animal; Duodenum; Electric Stimulati

2008
Optogenetic analysis of synaptic function.
    Nature methods, 2008, Volume: 5, Issue:10

    Topics: Acetylcholine; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Carrier Proteins; gam

2008
An insight on the neuropharmacological activity of Telescopium telescopium--a mollusc from the Sunderban mangrove.
    Fundamental & clinical pharmacology, 2008, Volume: 22, Issue:6

    Topics: Animals; Behavior, Animal; Body Temperature; Brain; Central Nervous System Depressants; Disease Mode

2008
Endogenous gamma-aminobutyric acid modulates tonic guinea pig airway tone and propofol-induced airway smooth muscle relaxation.
    Anesthesiology, 2009, Volume: 110, Issue:4

    Topics: Acetylcholine; Anesthetics, Intravenous; Animals; Chromatography, High Pressure Liquid; Dose-Respons

2009
Functional evidence for different roles of GABAA and GABAB receptors in modulating mouse gastric tone.
    Neuropharmacology, 2010, Volume: 58, Issue:7

    Topics: Animals; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Rec

2010
A genetic survey of fluoxetine action on synaptic transmission in Caenorhabditis elegans.
    Genetics, 2010, Volume: 186, Issue:3

    Topics: Acetylcholine; Animals; Behavior, Animal; Biological Assay; Caenorhabditis elegans; Caenorhabditis e

2010
Effect of GABA-ergic mechanisms on synaptosomal NO synthesis and the nitrergic component of NANC relaxation in rat ileum.
    Neurogastroenterology and motility, 2011, Volume: 23, Issue:5

    Topics: Animals; GABA Antagonists; gamma-Aminobutyric Acid; Ileum; Male; Muscle Relaxation; Muscle, Smooth;

2011
Airway epithelium is a predominant source of endogenous airway GABA and contributes to relaxation of airway smooth muscle tone.
    American journal of physiology. Lung cellular and molecular physiology, 2013, Feb-01, Volume: 304, Issue:3

    Topics: Acetylcholine; Animals; Cholinergic Agonists; Chromatography, High Pressure Liquid; GABA Plasma Memb

2013
Inhibitory effects of GABA(B) receptor agonists on swallowing in the dog.
    European journal of pharmacology, 2002, Jul-12, Volume: 448, Issue:1

    Topics: Animals; Baclofen; Deglutition; Dogs; Esophagogastric Junction; GABA-B Receptor Agonists; gamma-Amin

2002
Activation of the midbrain periaqueductal gray induces airway smooth muscle relaxation.
    Journal of applied physiology (Bethesda, Md. : 1985), 2002, Volume: 93, Issue:2

    Topics: Animals; Autonomic Fibers, Preganglionic; Bicuculline; Blood Pressure; Ferrets; GABA Antagonists; ga

2002
Electrically stimulated relaxation is not mediated by GABA in cat lower esophageal sphincter muscle.
    Archives of pharmacal research, 2006, Volume: 29, Issue:5

    Topics: Animals; Cats; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Esophageal

2006
Investigation of the mechanism for the relaxation of rat duodenum mediated via M1 muscarinic receptors.
    Autonomic & autacoid pharmacology, 2006, Volume: 26, Issue:3

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bicuculline; Dose-Res

2006
The anxioselective agent 7-(2-chloropyridin-4-yl)pyrazolo-[1,5-a]-pyrimidin-3-yl](pyridin-2-yl)methanone (DOV 51892) is more efficacious than diazepam at enhancing GABA-gated currents at alpha1 subunit-containing GABAA receptors.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Ataxia; Chloride Channels; Diazepam; Dose-Response Relationship, Drug;

2006
Anxiolytic-like effects of sinapic acid in mice.
    Life sciences, 2007, Jun-27, Volume: 81, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Bicuculline; Cerebral Cortex; Chloride Channels; Coumaric Aci

2007
Evidence that GABAA receptors mediate relaxation of rat duodenum by activating intramural nonadrenergic-noncholinergic neurones.
    Journal of autonomic pharmacology, 1984, Volume: 4, Issue:2

    Topics: Animals; Duodenum; gamma-Aminobutyric Acid; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smo

1984
Neuropharmacology of buspirone.
    Psychopathology, 1984, Volume: 17 Suppl 3

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Biomechanical Phenomena; Buspirone;

1984
Closing of membrane channels effected by gamma-amino-butyric acid (GABA) in crayfish muscle.
    Pflugers Archiv : European journal of physiology, 1980, Volume: 387, Issue:2

    Topics: Animals; Astacoidea; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Membranes; Muscle R

1980
Effects of homopantothenic acid on intestinal smooth muscles.
    The Tohoku journal of experimental medicine, 1983, Volume: 140, Issue:1

    Topics: Animals; Colon; gamma-Aminobutyric Acid; Gastrointestinal Motility; Guinea Pigs; Ileum; Male; Muscle

1983
Two actions of gamma-aminobutyric acid on the responses of the isolated basilar artery from the rabbit.
    British journal of pharmacology, 1982, Volume: 75, Issue:1

    Topics: Animals; Baclofen; Basilar Artery; Drug Interactions; Electric Stimulation; Female; GABA Antagonists

1982
Some pharmacological studies on the spastic mouse.
    British journal of pharmacology, 1982, Volume: 75, Issue:1

    Topics: Animals; Anticonvulsants; Benzodiazepines; Electromyography; Female; gamma-Aminobutyric Acid; Male;

1982
Inhibitory synaptic channels activated by gamma-aminobutyric acid (GABA) in crayfish muscle.
    Pflugers Archiv : European journal of physiology, 1980, Volume: 387, Issue:2

    Topics: Animals; Astacoidea; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Muscle Relax

1980
Effects of dantrolene sodium on gabaergic activity in spinal cord, corpus striatum, substantia nigra and cerebral cortex in rat.
    Acta neurologica, 1981, Volume: 3, Issue:2

    Topics: Animals; Brain; Cerebral Cortex; Corpus Striatum; Dantrolene; gamma-Aminobutyric Acid; Male; Muscle

1981
Reversal of a muscle response to GABA during C. elegans male development.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:9

    Topics: Aging; Anal Canal; Animals; Caenorhabditis elegans; Constipation; Defecation; gamma-Aminobutyric Aci

1995
Interplay of somatostatin, opioid, and GABA neurons in the regulation of the peristaltic reflex.
    The American journal of physiology, 1994, Volume: 267, Issue:4 Pt 1

    Topics: Animals; Antibodies; Bicuculline; Colon; Enkephalin, Methionine; gamma-Aminobutyric Acid; In Vitro T

1994
A nematode FMRFamide-like peptide, SDPNFLRFamide (PF1), relaxes the dorsal muscle strip preparation of Ascaris suum.
    Parasitology, 1994, Volume: 108 ( Pt 2)

    Topics: Acetylcholine; Animals; Ascaris suum; Dose-Response Relationship, Drug; Electrophysiology; Female; F

1994
Biphasic GABA-A receptor-mediated effect on the spontaneous activity of the circular layer in cat terminal ileum.
    General pharmacology, 1993, Volume: 24, Issue:4

    Topics: Animals; Atropine; Baclofen; Bicuculline; Cats; gamma-Aminobutyric Acid; Ileum; In Vitro Techniques;

1993
Prejunctional modulation of the nitrergic innervation of the canine ileocolonic junction via potassium channels.
    British journal of pharmacology, 1993, Volume: 110, Issue:2

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Autonomic Nervous System; Colon; Dogs; Electric Stim

1993
[Effects of gamma-aminobutyric acid on isolated dog cerebral arteries].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1995, Volume: 30, Issue:8

    Topics: Animals; Basilar Artery; Dogs; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscle Re

1995
Two types of functionally different GABAA receptors mediate GABA modulation of cholinergic transmission in cat terminal ileum.
    Journal of autonomic pharmacology, 1995, Volume: 15, Issue:4

    Topics: Animals; Atropine; Bicuculline; Cats; Dose-Response Relationship, Drug; Electric Stimulation; GABA A

1995
Rat gastroduodenal motility in vivo: interaction of GABA and VIP in control of spontaneous relaxations.
    The American journal of physiology, 1998, Volume: 275, Issue:5

    Topics: Animals; Bicuculline; Duodenum; GABA Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid;

1998
Examination of the relationships between jaw opener and closer rhythmical muscle activity in an in vitro brainstem jaw-attached preparation.
    Somatosensory & motor research, 1998, Volume: 15, Issue:3

    Topics: Animals; Bicuculline; Brain Stem; Electromyography; GABA Antagonists; gamma-Aminobutyric Acid; Jaw;

1998
Neuropsychopharmacological profile of the methanolic fraction of Bryophyllum pinnatum leaf extract.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:3

    Topics: Analgesia; Animals; Anticonvulsants; Behavior, Animal; Brain Chemistry; Dose-Response Relationship,

1999
GABAergic inhibition of nitric oxide-mediated relaxation of guinea-pig ileum.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 359, Issue:6

    Topics: Animals; Bicuculline; Electric Stimulation; Enzyme Inhibitors; Female; GABA Agonists; GABA-A Recepto

1999
Effects of diabetes on non-adrenergic, non-cholinergic relaxation induced by GABA and electrical stimulation in the rat isolated duodenum.
    Clinical and experimental pharmacology & physiology, 1999, Volume: 26, Issue:9

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Duodenum; Electric Stimulation

1999
Inhibition of transient LES relaxations and reflux in ferrets by GABA receptor agonists.
    The American journal of physiology, 1999, Volume: 277, Issue:4

    Topics: Animals; Baclofen; Behavior, Animal; Deglutition; Esophagogastric Junction; Female; Ferrets; GABA Ag

1999
Effect of hydroquinone, hydroxocobalamin and carboxy-PTIO on non-adrenergic non-cholinergic nerve mediated relaxations of the rat duodenum.
    Journal of autonomic pharmacology, 1999, Volume: 19, Issue:4

    Topics: Animals; Autonomic Nervous System; Benzoates; Duodenum; Electric Stimulation; gamma-Aminobutyric Aci

1999
Nitric oxide-mediated endothelium-dependent relaxation of rat thoracic aorta induced by aqueous extract of red rice fermented with Monascus ruber.
    Journal of ethnopharmacology, 2000, Volume: 70, Issue:1

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Ascomycota; Cells, Cultured; Endothelium, Vascular; Ferment

2000
Brain mechanisms associated with therapeutic actions of benzodiazepines: focus on neurotransmitters.
    The American journal of psychiatry, 1977, Volume: 134, Issue:6

    Topics: Anti-Anxiety Agents; Barbiturates; Benzodiazepines; Binding Sites; Brain; Brain Stem; gamma-Aminobut

1977
Involvement of gamma-amino butyric acid (GABA) in the anticonvulsant action of methaqualone.
    Psychopharmacology, 1978, Apr-14, Volume: 57, Issue:1

    Topics: Aminobutyrates; Animals; Anticonvulsants; Brain Chemistry; Cerebellum; Diazepam; gamma-Aminobutyric

1978
Neuropharmacology of amide derivatives of P-GABA.
    Indian journal of experimental biology, 1992, Volume: 30, Issue:7

    Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Bicuculline; Brain; gamma-Aminobutyric Acid; Hyp

1992
Effect of L-NG-nitro-arginine (L-NOARG) on the relaxation induced by gamma-aminobutyric acid (GABA) and vasoactive intestinal peptide (VIP) in rat isolated duodenum.
    Japanese journal of pharmacology, 1992, Volume: 58 Suppl 2

    Topics: Animals; Arginine; Duodenum; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscle Relaxation;

1992
Evidence for nitric oxide as mediator of non-adrenergic non-cholinergic relaxations induced by ATP and GABA in the canine gut.
    British journal of pharmacology, 1991, Volume: 102, Issue:2

    Topics: Adenosine Triphosphate; Animals; Arginine; Colon; Dogs; Female; gamma-Aminobutyric Acid; Ileum; In V

1991
Neuropharmacological studies on the venom of Vipera russelli.
    Indian journal of experimental biology, 1991, Volume: 29, Issue:10

    Topics: Aggression; Animals; Behavior, Animal; Body Temperature; Brain; Chlorpromazine; Dose-Response Relati

1991
Myorelaxant effect of baclofen injected to the nucleus accumbens septi.
    Journal of neural transmission. Parkinson's disease and dementia section, 1990, Volume: 2, Issue:3

    Topics: Animals; Baclofen; Behavior, Animal; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Halo

1990
Differences in the effects (in vitro) of ethylenediamine on the guinea-pig and rat intestine.
    European journal of pharmacology, 1990, Feb-20, Volume: 177, Issue:1-2

    Topics: Animals; Baclofen; Bicuculline; Electric Stimulation; Ethylenediamines; Female; gamma-Aminobutyric A

1990
Effect of gamma-aminobutyric acid (GABA) on vasodilation in resistance-sized arteries isolated from the monkey, rabbit, and rat.
    Journal of cardiovascular pharmacology, 1988, Volume: 12, Issue:3

    Topics: Animals; Arteries; Bicuculline; Dinoprost; gamma-Aminobutyric Acid; In Vitro Techniques; Macaca fasc

1988
Actions of anaesthetics and avermectin on GABAA chloride channels in mammalian dorsal root ganglion neurones.
    British journal of pharmacology, 1989, Volume: 98, Issue:1

    Topics: Anesthetics; Animals; Cats; Cell Membrane; Chlorides; gamma-Aminobutyric Acid; Ganglia, Spinal; Hydr

1989
The motor response to ethylenediamine of the rat isolated duodenum: involvement of GABAergic transmission?
    Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 340, Issue:4

    Topics: 3-Mercaptopropionic Acid; Animals; Benzalkonium Compounds; Duodenum; Ethylenediamines; gamma-Aminobu

1989
An in vitro study of the relationship between GABA receptor function and propulsive motility in the distal colon of the rabbit.
    British journal of pharmacology, 1989, Volume: 98, Issue:4

    Topics: Amino Acids; Amino Acids, Neutral; Animals; Autonomic Nervous System; Baclofen; Colon; gamma-Aminobu

1989
Synthesis and anticonvulsant activity of N-phthaloyl GABA--a new GABA derivative.
    Indian journal of experimental biology, 1989, Volume: 27, Issue:9

    Topics: Animals; Anticonvulsants; gamma-Aminobutyric Acid; Locomotion; Male; Mice; Muscle Relaxation; Rabbit

1989
Pharmacological evidence that at least two different non-adrenergic non-cholinergic inhibitory systems are present in the rat small intestine.
    European journal of pharmacology, 1986, Apr-16, Volume: 123, Issue:2

    Topics: Adenosine Triphosphate; Animals; Chymotrypsin; Dimethylphenylpiperazinium Iodide; Duodenum; Electric

1986
Evaluation of different GABA receptor agonists in the kindled amygdala seizure model in rats.
    Experimental neurology, 1985, Volume: 89, Issue:2

    Topics: Amygdala; Animals; Female; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Isoxazoles; Kindling, N

1985
Further evidence for involvement of adenosine-5'-triphosphate in non-adrenergic non-cholinergic relaxation of the isolated rat duodenum.
    European journal of pharmacology, 1985, Jul-31, Volume: 113, Issue:3

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Autonomi

1985
Comparison of GABA-induced responses in various segments of the guinea-pig intestine.
    European journal of pharmacology, 1987, Feb-24, Volume: 134, Issue:3

    Topics: Animals; Ethylenediamines; Female; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Intest

1987
A possible mechanism on the potentiating vascular effect of coadministration of ifenprodil tartrate and calcium hopantenate: a study in the internal carotid artery.
    International journal of clinical pharmacology, therapy, and toxicology, 1988, Volume: 26, Issue:9

    Topics: Animals; Blood Flow Velocity; Calcium; Carotid Artery, Internal; Cerebrovascular Disorders; Dogs; Dr

1988
Ascaris suum: regulation of myosin light chain phosphorylation from adult skeletal muscle.
    Experimental parasitology, 1986, Volume: 61, Issue:1

    Topics: Acetylcholine; Animals; Ascaris; Female; gamma-Aminobutyric Acid; Muscle Contraction; Muscle Relaxat

1986