gamma-aminobutyric acid has been researched along with Muscle Disorders in 13 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pregabalin is used for treatment of neuropathic pain conditions." | 7.74 | Pregabalin reduces muscle and cutaneous hyperalgesia in two models of chronic muscle pain in rats. ( Audette, KM; Maeda, Y; Sluka, KA; Yokoyama, T, 2007) |
| "This study shows that pregabalin reduces both cutaneous and muscle hyperalgesia in inflammatory and noninflammatory models of muscle pain." | 7.74 | Pregabalin reduces muscle and cutaneous hyperalgesia in two models of chronic muscle pain in rats. ( Audette, KM; Maeda, Y; Sluka, KA; Yokoyama, T, 2007) |
| "Patients with amyotrophic lateral sclerosis have increased levels of the neutrotransmitter norepinephrine in blood and cerebrospinal fluid and depressed levels of the inhibitory neurotransmitter gamma-aminobutyric acid in cerebrospinal fluid." | 7.66 | Norepinephrine and gamma-aminobutyric acid in amyotrophic lateral sclerosis. ( Brooks, BR; Enna, SJ; Lake, CR; Wood, JH; Ziegler, MG, 1980) |
| "Muscle hyperalgesia (withdrawal threshold to compression of the muscle) and cutaneous hyperalgesia of the paw (withdrawal threshold to von Frey filaments) were measured before and after induction of hyperalgesia and after treatment with pregabalin (saline, 10 to 100 mg/kg i." | 5.34 | Pregabalin reduces muscle and cutaneous hyperalgesia in two models of chronic muscle pain in rats. ( Audette, KM; Maeda, Y; Sluka, KA; Yokoyama, T, 2007) |
| "Chronic muscle pain is a problem with high prevalence in clinical practice and its pharmacological treatment is difficult." | 5.34 | Antihyperalgesic efficacy of lacosamide in a rat model for muscle pain induced by TNF. ( Beyreuther, BK; Geis, C; Sommer, C; Stöhr, T, 2007) |
| "A complete reversal of hyperalgesia was seen with lacosamide at 30mg/kg." | 5.34 | Antihyperalgesic efficacy of lacosamide in a rat model for muscle pain induced by TNF. ( Beyreuther, BK; Geis, C; Sommer, C; Stöhr, T, 2007) |
| "Pregabalin is used for treatment of neuropathic pain conditions." | 3.74 | Pregabalin reduces muscle and cutaneous hyperalgesia in two models of chronic muscle pain in rats. ( Audette, KM; Maeda, Y; Sluka, KA; Yokoyama, T, 2007) |
| "This study shows that pregabalin reduces both cutaneous and muscle hyperalgesia in inflammatory and noninflammatory models of muscle pain." | 3.74 | Pregabalin reduces muscle and cutaneous hyperalgesia in two models of chronic muscle pain in rats. ( Audette, KM; Maeda, Y; Sluka, KA; Yokoyama, T, 2007) |
| "To report and discuss a case of rhabdomyolysis in an elderly patient with neuropathic pain who was treated with gabapentin." | 3.74 | Gabapentin-induced severe myopathy. ( Blandizzi, C; Del Tacca, M; Lapi, F; Lombardo, G; Tuccori, M; Vannacci, A, 2007) |
| "Patients with amyotrophic lateral sclerosis have increased levels of the neutrotransmitter norepinephrine in blood and cerebrospinal fluid and depressed levels of the inhibitory neurotransmitter gamma-aminobutyric acid in cerebrospinal fluid." | 3.66 | Norepinephrine and gamma-aminobutyric acid in amyotrophic lateral sclerosis. ( Brooks, BR; Enna, SJ; Lake, CR; Wood, JH; Ziegler, MG, 1980) |
| "Pyridoxine-sensitive seizures characterize severe forms of infantile HPP." | 1.46 | Neuromuscular features of hypophosphatasia. ( Fonta, C; Salles, JP, 2017) |
| "Muscle hyperalgesia (withdrawal threshold to compression of the muscle) and cutaneous hyperalgesia of the paw (withdrawal threshold to von Frey filaments) were measured before and after induction of hyperalgesia and after treatment with pregabalin (saline, 10 to 100 mg/kg i." | 1.34 | Pregabalin reduces muscle and cutaneous hyperalgesia in two models of chronic muscle pain in rats. ( Audette, KM; Maeda, Y; Sluka, KA; Yokoyama, T, 2007) |
| "Chronic muscle pain is a problem with high prevalence in clinical practice and its pharmacological treatment is difficult." | 1.34 | Antihyperalgesic efficacy of lacosamide in a rat model for muscle pain induced by TNF. ( Beyreuther, BK; Geis, C; Sommer, C; Stöhr, T, 2007) |
| "A complete reversal of hyperalgesia was seen with lacosamide at 30mg/kg." | 1.34 | Antihyperalgesic efficacy of lacosamide in a rat model for muscle pain induced by TNF. ( Beyreuther, BK; Geis, C; Sommer, C; Stöhr, T, 2007) |
| "Gabapentin was then withdrawn and the patient's condition rapidly improved." | 1.34 | Gabapentin-induced severe myopathy. ( Blandizzi, C; Del Tacca, M; Lapi, F; Lombardo, G; Tuccori, M; Vannacci, A, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (38.46) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fonta, C | 1 |
| Salles, JP | 1 |
| Nguyen, VH | 1 |
| Lawrence, HJ | 1 |
| Yokoyama, T | 1 |
| Maeda, Y | 1 |
| Audette, KM | 1 |
| Sluka, KA | 1 |
| Beyreuther, BK | 1 |
| Geis, C | 1 |
| Stöhr, T | 1 |
| Sommer, C | 1 |
| Tuccori, M | 1 |
| Lombardo, G | 1 |
| Lapi, F | 1 |
| Vannacci, A | 1 |
| Blandizzi, C | 1 |
| Del Tacca, M | 1 |
| Spiller, J | 1 |
| Lloyd, KG | 1 |
| Worms, P | 1 |
| Ziegler, MG | 1 |
| Brooks, BR | 1 |
| Lake, CR | 1 |
| Wood, JH | 1 |
| Enna, SJ | 1 |
| Takayanagi, M | 1 |
| Ogawa, A | 1 |
| van Deventer, H | 1 |
| Bernard, S | 1 |
| Sazonova, NS | 1 |
| Balashova, EG | 1 |
| Lapierre, YD | 1 |
| Elie, R | 1 |
| Tetreault, L | 1 |
| Brogden, RN | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Exploratory Study on the Use of Pregabalin for the Treatment of Taxol Related Arthralgia-Myalgia[NCT02024568] | Phase 2 | 38 participants (Anticipated) | Interventional | 2013-12-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for gamma-aminobutyric acid and Muscle Disorders
| Article | Year |
|---|---|
Neuropharmacological actions of GABA agonists: predictability for their clinical usefulness.
Topics: Antipsychotic Agents; Brain Chemistry; Dyskinesia, Drug-Induced; Epilepsy; gamma-Aminobutyric Acid; | 1981 |
[D-2-hydroxyglutaric aciduria].
Topics: Biomarkers; Cardiomyopathy, Dilated; Central Nervous System Diseases; Diagnosis, Differential; gamma | 1998 |
Baclofen: a preliminary report of its pharmacological properties and therapeutic efficacy in spasticity.
Topics: Adolescent; Adult; Aminobutyrates; Animals; Chlorobenzenes; Chronic Disease; Clinical Trials as Topi | 1974 |
2 trials available for gamma-aminobutyric acid and Muscle Disorders
| Article | Year |
|---|---|
The antispastic effects of Ba 34647 (B-4-p-chlorophenyl-gamma-amino-butyric acid) a GABA derivative.
Topics: Adult; Aminobutyrates; Analysis of Variance; Chlorobenzenes; Clinical Trials as Topic; Electromyogra | 1974 |
Baclofen: a preliminary report of its pharmacological properties and therapeutic efficacy in spasticity.
Topics: Adolescent; Adult; Aminobutyrates; Animals; Chlorobenzenes; Chronic Disease; Clinical Trials as Topi | 1974 |
9 other studies available for gamma-aminobutyric acid and Muscle Disorders
| Article | Year |
|---|---|
Neuromuscular features of hypophosphatasia.
Topics: Adult; Alkaline Phosphatase; Animals; Biomarkers; Brain Diseases; Chronic Pain; Disease Models, Anim | 2017 |
Use of gabapentin in the prevention of taxane-induced arthralgias and myalgias.
Topics: Acetates; Amines; Analgesics; Antineoplastic Agents, Phytogenic; Arthralgia; Cyclohexanecarboxylic A | 2004 |
Pregabalin reduces muscle and cutaneous hyperalgesia in two models of chronic muscle pain in rats.
Topics: Analgesics; Animals; Carrageenan; Chronic Disease; Disease Models, Animal; Dose-Response Relationshi | 2007 |
Antihyperalgesic efficacy of lacosamide in a rat model for muscle pain induced by TNF.
Topics: Acetamides; Amines; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Excitatory Amino Acid An | 2007 |
Gabapentin-induced severe myopathy.
Topics: Aged, 80 and over; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; | 2007 |
Acupuncture, ketamine and piriformis syndrome--a case report from palliative care.
Topics: Acupuncture Therapy; Amines; Analgesics; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Gab | 2007 |
Norepinephrine and gamma-aminobutyric acid in amyotrophic lateral sclerosis.
Topics: Adult; Amyotrophic Lateral Sclerosis; Female; gamma-Aminobutyric Acid; Humans; Male; Muscular Diseas | 1980 |
Use of gabapentin to treat taxane-induced myalgias.
Topics: Acetates; Amines; Analgesics; Antineoplastic Agents, Phytogenic; Cyclohexanecarboxylic Acids; Doceta | 1999 |
[Experience with clinical use of the drug gammalon in children with cerebral palsy].
Topics: Adolescent; Aminobutyrates; Cerebral Palsy; Child; Child, Preschool; Electromyography; Feeding and E | 1974 |