Page last updated: 2024-10-16

gamma-aminobutyric acid and Movement Disorders

gamma-aminobutyric acid has been researched along with Movement Disorders in 83 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.

Research Excerpts

ExcerptRelevanceReference
"Treatment by progabide, a GABA-agonist, was successful in one case: a gradual improvement was observed during four weeks and the movements have now disappeared after six months of progabide therapy."5.27[Progabide treatment of a case of the syndrome of painful legs and moving toes]. ( Bovier, P; Hilleret, H; Tissot, R, 1985)
"In childhood, movement disorders are generated by a very large number of disorders of the nervous system, and the very different developmental ages at which these occur make studies of pharmacotherapy efficacy extremely difficult."2.55Advances in pharmacotherapies for movement disorders in children: current limitations and future progress. ( Lin, JP, 2017)
"Among psychiatric disorders the acute symptoms of schizophrenia are exacerbated by enhanced GABA-ergic function."2.36Pharmacology of GABA. ( Meldrum, B, 1982)
"Stroke is a leading cause of adult disability owing largely to motor impairment and loss of function."1.51The Influence of Primary Motor Cortex Inhibition on Upper Limb Impairment and Function in Chronic Stroke: A Multimodal Study. ( Ackerley, SJ; Barber, PA; Byblow, WD; Cirillo, J; Mooney, RA; Rajeswaran, DK; Stinear, CM, 2019)
"Gamma-aminobutyric acid (GABA) is a major modulator in brain maturation and its role in many different neurodevelopmental disorders has been widely reported."1.48Gamma-aminobutyric acid levels in cerebrospinal fluid in neuropaediatric disorders. ( Armstrong-Morón, J; Artuch, R; Casado, M; Cortès-Saladelafont, E; Cuadras, D; García-Cazorla, À; Molero-Luis, M; Montoya, J; Yubero, D, 2018)
" Chronic administration of haloperidol (1 mg/kg, i."1.35Progesterone attenuates neuroleptic-induced orofacial dyskinesia via the activity of its metabolite, allopregnanolone, a positive GABA(A) modulating neurosteroid. ( Bishnoi, M; Chopra, K; Kulkarni, SK, 2008)
"These findings suggest that progressive hydrocephalus results in functional injuries of cholinergic and GABAergic neurons in the neostriatum and dopaminergic neurons in the substantia nigra compacta by mechanical distortion."1.30Functional injury of cholinergic, GABAergic and dopaminergic systems in the basal ganglia of adult rat with kaolin-induced hydrocephalus. ( Chakrabortty, S; Drake, JM; Hattori, T; Tashiro, Y, 1997)
"Hydrocephalus was induced in 12 Wistar rats by intracisternal injection of 0."1.30Functional injury of cholinergic, GABAergic and dopaminergic systems in the basal ganglia of adult rat with kaolin-induced hydrocephalus. ( Chakrabortty, S; Drake, JM; Hattori, T; Tashiro, Y, 1997)
"The pathophysiology of idiopathic dystonia, characterized by sustained twisting movements and postures, is still unknown."1.30Alterations in spontaneous single unit activity of striatal subdivisions during ontogenesis in mutant dystonic hamsters. ( Gernert, M; Löscher, W; Richter, A, 1999)
" This effect which was quantified in terms of numbers of tongue protrusions, was dose-dependent: a bell-shaped dose-response was found (50-500 ng)."1.29Interactions of the subthalamic nucleus and the subpallidal area in oro-facial dyskinesia: role of GABA and glutamate. ( Cools, AR; Helfrich, SE; Spooren, WP, 1995)
"Treatment by progabide, a GABA-agonist, was successful in one case: a gradual improvement was observed during four weeks and the movements have now disappeared after six months of progabide therapy."1.27[Progabide treatment of a case of the syndrome of painful legs and moving toes]. ( Bovier, P; Hilleret, H; Tissot, R, 1985)

Research

Studies (83)

TimeframeStudies, this research(%)All Research%
pre-199040 (48.19)18.7374
1990's9 (10.84)18.2507
2000's19 (22.89)29.6817
2010's13 (15.66)24.3611
2020's2 (2.41)2.80

Authors

AuthorsStudies
Feng, H1
Yuan, Y1
Williams, MR1
Roy, AJ1
Leipprandt, JR1
Neubig, RR1
Li, HQ1
Spitzer, NC1
Lin, JP1
Cortès-Saladelafont, E1
Molero-Luis, M1
Cuadras, D1
Casado, M1
Armstrong-Morón, J1
Yubero, D1
Montoya, J1
Artuch, R1
García-Cazorla, À1
Alvarado-Franco, NL1
Gonzalez-Marques, C1
Olguín-Ramírez, LA1
Garza-Alpirez, A1
Femat-Roldan, G1
Martinez-Ramirez, D1
Mooney, RA1
Ackerley, SJ1
Rajeswaran, DK1
Cirillo, J1
Barber, PA1
Stinear, CM1
Byblow, WD1
Bhattacharyya, PK1
Phillips, MD1
Stone, LA1
Bermel, RA1
Lowe, MJ1
Helmich, RC1
Toni, I1
Deuschl, G1
Bloem, BR1
Boecker, H1
Carelli, S1
Giallongo, T1
Viaggi, C1
Gombalova, Z1
Latorre, E1
Mazza, M1
Vaglini, F1
Di Giulio, AM1
Gorio, A1
Fourcade, G1
Roubertie, A1
Doummar, D1
Vidailhet, M1
Labauge, P1
Gharibzadeh, S1
Sarbaz, Y1
Banaie, M1
Towhidkhah, F1
Sherin, A1
Peeyush, KT1
Naijil, G1
Chinthu, R1
Paulose, CS1
Arinami, T1
Inada, T1
Fatemi, SH1
Aldinger, KA1
Ashwood, P1
Bauman, ML1
Blaha, CD1
Blatt, GJ1
Chauhan, A1
Chauhan, V1
Dager, SR1
Dickson, PE1
Estes, AM1
Goldowitz, D1
Heck, DH1
Kemper, TL1
King, BH1
Martin, LA1
Millen, KJ1
Mittleman, G1
Mosconi, MW1
Persico, AM1
Sweeney, JA1
Webb, SJ1
Welsh, JP1
Gittis, AH1
Kreitzer, AC1
Teo, JT1
Edwards, MJ1
Bhatia, K1
Ugawa, Y1
Hanajima, R1
Fedrowitz, M1
Lindemann, S1
Löscher, W2
Gernert, M2
Ackley, BD1
Kang, SH1
Crew, JR1
Suh, C1
Jin, Y1
Kramer, JM1
Ravizza, T1
Friedman, LK1
Moshé, SL1
Velísková, J1
BERTAMINO, F1
VENTO, R1
Ethofer, T1
Seeger, U1
Klose, U1
Erb, M1
Kardatzki, B1
Kraft, E1
Landwehrmeyer, GB1
Grodd, W1
Storch, A1
Villarejo, A1
Porta-Etessam, J1
Camacho, A1
González De La Aleja, J1
Martínez-Salio, A1
Penas, M1
de Lago, E1
Fernández-Ruiz, J2
Ortega-Gutiérrez, S1
Cabranes, A1
Pryce, G1
Baker, D1
López-Rodríguez, M1
Ramos, JA1
Gonzáles, S1
Hess, CW1
Saunders-Pullman, R1
Di Giovanni, G1
Di Matteo, V1
Pierucci, M1
Benigno, A1
Esposito, E1
Galvan, A1
Wichmann, T1
Bishnoi, M1
Chopra, K1
Kulkarni, SK1
Manson, SC1
Wegner, C1
Filippi, M1
Barkhof, F1
Beckmann, C1
Ciccarelli, O1
De Stefano, N1
Enzinger, C1
Fazekas, F1
Agosta, F1
Gass, A1
Hirsch, J1
Johansen-Berg, H1
Kappos, L1
Korteweg, T1
Polman, C1
Mancini, L1
Manfredonia, F1
Marino, S1
Miller, DH1
Montalban, X1
Palace, J1
Rocca, M1
Ropele, S1
Rovira, A1
Smith, S1
Thompson, A1
Thornton, J1
Yousry, T1
Frank, JA1
Matthews, PM1
Aberg, L1
Talling, M1
Härkönen, T1
Lönnqvist, T1
Knip, M1
Alen, R1
Rantala, H1
Tyynelä, J1
Wray, SR1
Melville, GN1
Grell, GA1
Edge, PC1
Chapman, A1
Keane, PE1
Meldrum, BS1
Simiand, J1
Vernieres, JC1
Becker, RE1
Lal, H1
Scheel-Krüger, J2
Gonce, M1
Schoenen, J1
Charlier, M1
Delwaide, PJ1
Meldrum, B1
Zivkovic, B1
Scatton, B1
Worms, P1
Lloyd, KG1
Bartholini, G2
Ando, K1
Marsden, CD1
Sheehy, MP1
Chesire, RM1
Cheng, JT1
Teitelbaum, P1
Nakamura, S1
Kameyama, M1
Rector, WG1
Herlong, HF1
Moses, H1
Kilpatrick, IC1
Collingridge, GL1
Starr, MS1
Izumi, K1
Munekata, E1
Yamamoto, H1
Nakanishi, T1
Barbeau, A2
Lesný, I1
Takamatsu, K1
Ohta, T1
Sato, S1
Sano, A1
Takahashi, K1
Murakami, Y1
Yoshihisa, K1
Sato, M1
Ohta, K1
Spooren, WP2
Helfrich, SE1
Cools, AR3
Weindl, A1
Kuwert, T1
Leenders, KL1
Poremba, M1
Gräfin von Einsiedel, H1
Antonini, A1
Herzog, H1
Scholz, D1
Feinendegen, LE1
Conrad, B1
Elble, RJ1
Chaná, P1
de Marinis, A1
Barrientos, N1
Tashiro, Y1
Drake, JM1
Chakrabortty, S1
Hattori, T1
Richter, A1
Magnus, L1
Chadha, A1
Sur, C1
Atack, J1
Duty, S1
Dostrovsky, JO1
Lozano, AM1
Klawans, HL1
Weiner, WJ1
Calne, DB1
Eisler, T1
Van Rossum, JM1
Siggins, GR1
Henriksen, SJ1
Landis, SC1
Costall, B1
Naylor, RJ1
Owen, RT1
Di Chiara, G1
Morelli, M1
Porceddu, ML1
Gessa, GL1
Wolfarth, S1
Aizawa, H1
Kwak, S1
Shimizu, T1
Mannen, T1
Shibasaki, H1
Cuypers, E1
Larson, AA1
Hashimoto, M1
Yokota, A1
Matsuoka, S1
Shima, F1
Matin, MA1
Hussain, K1
Cross, AJ1
Crow, TJ1
Ferrier, IN1
Johnson, JA1
Johnstone, EC1
Owen, F1
Owens, DG1
Poulter, M1
Sandyk, R1
Rondot, P1
Bergmann, KJ1
Bovier, P1
Hilleret, H1
Tissot, R1
Menza, M1
Gottlieb, D1
Shahin, D1
Stahl, SM1
Thornton, JE1
Simpson, ML1
Berger, PA1
Napoliello, MJ1
Tobe, A1
Egawa, M1
Saito, K1
Hashimoto, N1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Modulation of the Activity in the Cerebellum With Transcranial Direct Current Stimulation in Autistic Participants[NCT05781412]100 participants (Anticipated)Interventional2022-05-24Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

31 reviews available for gamma-aminobutyric acid and Movement Disorders

ArticleYear
Advances in pharmacotherapies for movement disorders in children: current limitations and future progress.
    Current opinion in pediatrics, 2017, Volume: 29, Issue:6

    Topics: Amines; Anti-Dyskinesia Agents; Child; Clonidine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Ami

2017
The pathophysiology of essential tremor and Parkinson's tremor.
    Current neurology and neuroscience reports, 2013, Volume: 13, Issue:9

    Topics: Animals; Electric Stimulation Therapy; Essential Tremor; gamma-Aminobutyric Acid; Humans; Movement D

2013
Imaging the role of GABA in movement disorders.
    Current neurology and neuroscience reports, 2013, Volume: 13, Issue:10

    Topics: Brain; gamma-Aminobutyric Acid; Humans; Movement Disorders; Neuroimaging

2013
[Genome-wide association analyses for neuroleptic-induced tardive dyskinesia].
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2011, Volume: 31, Issue:4

    Topics: Acetylcholine; Animals; Antipsychotic Agents; gamma-Aminobutyric Acid; Genetic Predisposition to Dis

2011
Consensus paper: pathological role of the cerebellum in autism.
    Cerebellum (London, England), 2012, Volume: 11, Issue:3

    Topics: Animals; Autistic Disorder; Cell Adhesion Molecules, Neuronal; Cerebellar Diseases; Cerebellum; Cogn

2012
Striatal microcircuitry and movement disorders.
    Trends in neurosciences, 2012, Volume: 35, Issue:9

    Topics: Animals; Corpus Striatum; gamma-Aminobutyric Acid; Humans; Movement Disorders; Nerve Net; Receptors,

2012
Tardive dyskinesia is caused by maladaptive synaptic plasticity: a hypothesis.
    Movement disorders : official journal of the Movement Disorder Society, 2012, Sep-01, Volume: 27, Issue:10

    Topics: Adaptation, Physiological; Antipsychotic Agents; Corpus Striatum; Excitatory Amino Acid Agents; gamm

2012
[Transcranial magnetic stimulation (TMS) in movement disorders].
    Rinsho shinkeigaku = Clinical neurology, 2001, Volume: 41, Issue:12

    Topics: Basal Ganglia; gamma-Aminobutyric Acid; Humans; Motor Cortex; Movement Disorders; Neural Inhibition;

2001
Cannabinoid control of motor function at the basal ganglia.
    Handbook of experimental pharmacology, 2005, Issue:168

    Topics: Animals; Basal Ganglia; Cannabinoid Receptor Modulators; Cannabinoids; Dopamine; gamma-Aminobutyric

2005
Movement disorders and alcohol misuse.
    Addiction biology, 2006, Volume: 11, Issue:2

    Topics: Adjuvants, Anesthesia; Alcohol Drinking; Brain; Comorbidity; Dystonic Disorders; Essential Tremor; E

2006
Serotonin involvement in the basal ganglia pathophysiology: could the 5-HT2C receptor be a new target for therapeutic strategies?
    Current medicinal chemistry, 2006, Volume: 13, Issue:25

    Topics: Animals; Basal Ganglia Diseases; Central Nervous System; gamma-Aminobutyric Acid; Humans; Movement D

2006
GABAergic circuits in the basal ganglia and movement disorders.
    Progress in brain research, 2007, Volume: 160

    Topics: Animals; Basal Ganglia; GABA Modulators; gamma-Aminobutyric Acid; Humans; Movement Disorders; Neural

2007
Current concepts of abnormal motor disorder: an experimental model of attentional deficit disorder.
    The West Indian medical journal, 1981, Volume: 30, Issue:3

    Topics: Amphetamine; Animals; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Avoidance

1981
Mechanism of anticonvulsant action of valproate.
    Progress in neurobiology, 1982, Volume: 19, Issue:4

    Topics: Animals; Aspartic Acid; Cats; Central Nervous System; Epilepsy; gamma-Aminobutyric Acid; Half-Life;

1982
Pharmacological approaches to treatment of hemiballism and hemichorea.
    Brain research bulletin, 1983, Volume: 11, Issue:2

    Topics: Acetylcholine; Antipsychotic Agents; Basal Ganglia; Cerebrovascular Disorders; Chorea; Diazepam; Dop

1983
GABA in the striatonigral and striatopallidal systems as moderator and mediator of striatal functions.
    Advances in neurology, 1984, Volume: 40

    Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Catalepsy; Corpus Striatum; Diencephalon; gam

1984
Pharmacology of GABA.
    Clinical neuropharmacology, 1982, Volume: 5, Issue:3

    Topics: 4-Aminobutyrate Transaminase; Anxiety Disorders; Autonomic Nervous System; Barbiturates; Benzodiazep

1982
GABA system, GABA receptor agonists and dyskinesia.
    Modern problems of pharmacopsychiatry, 1983, Volume: 21

    Topics: Basal Ganglia; Cholinergic Fibers; Dopamine; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Huma

1983
[Biogenic amines to the pathophysiology of involuntary movements and cerebellar ataxia (author's transl)].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1981, Volume: 26, Issue:11

    Topics: Adolescent; Biogenic Amines; Brain; Cerebellar Ataxia; Child; Child, Preschool; Dystonia; gamma-Amin

1981
[Biochemical aspects of involuntary movements (author's transl)].
    No to shinkei = Brain and nerve, 1981, Volume: 33, Issue:12

    Topics: Adenosine Triphosphate; Brain; Calcium; Dopamine; gamma-Aminobutyric Acid; Humans; Levodopa; Movemen

1981
Possible involvement of taurine and GABA in morphine-like peptide actions.
    International journal of neurology, 1980, Volume: 14, Issue:2-4

    Topics: Amino Acids; Analgesia; Animals; Enkephalin, Methionine; gamma-Aminobutyric Acid; Humans; Male; Moto

1980
[Two diabetics with hemichorea-hemiballism and striatal lesions].
    No to shinkei = Brain and nerve, 1995, Volume: 47, Issue:2

    Topics: Aged; Chorea; Corpus Striatum; Diabetes Complications; Female; gamma-Aminobutyric Acid; Humans; Magn

1995
Central mechanisms of tremor.
    Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 1996, Volume: 13, Issue:2

    Topics: Basal Ganglia; Cerebellum; Dopamine; gamma-Aminobutyric Acid; Glutamates; Humans; Mesencephalon; Mov

1996
Nonepileptic uses of gabapentin.
    Epilepsia, 1999, Volume: 40 Suppl 6

    Topics: Acetates; Amines; Analgesics; Antimanic Agents; Antiparkinson Agents; Bipolar Disorder; Clinical Tri

1999
Mechanisms of deep brain stimulation.
    Movement disorders : official journal of the Movement Disorder Society, 2002, Volume: 17 Suppl 3

    Topics: Animals; Basal Ganglia; Electric Stimulation Therapy; gamma-Aminobutyric Acid; Humans; Movement Diso

2002
The pharmacology of choreatic movement disorders.
    Progress in neurobiology, 1976, Volume: 6, Issue:1

    Topics: Acetylcholine; Acute Disease; Amphetamine; Chorea; Dopamine; gamma-Aminobutyric Acid; Hepatolenticul

1976
The pathogensis and medical treatment of extrapyramidal disease.
    The Medical clinics of North America, 1979, Volume: 63, Issue:4

    Topics: Adult; Athetosis; Basal Ganglia Diseases; Caudate Nucleus; Chorea; Corpus Striatum; Dopamine; Dopami

1979
Experimental basis of the therapy of Parkinson's disease and the cholinergic-dopaminergic equilibrium in basal brain nuclei.
    Polish journal of pharmacology and pharmacy, 1976, Volume: 28, Issue:5

    Topics: Animals; Apomorphine; Basal Ganglia Diseases; Behavior, Animal; Brain; Carbachol; Caudate Nucleus; C

1976
The endogenous opioid system in neurological disorders of the basal ganglia.
    Life sciences, 1985, Nov-04, Volume: 37, Issue:18

    Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Clonidine; Endorphins; gamma-Aminobutyric Aci

1985
Progabide: a new GABA-mimetic agent in clinical use.
    Clinical neuropharmacology, 1985, Volume: 8, Issue:1

    Topics: Anticonvulsants; Brain Chemistry; Chemical Phenomena; Chemistry; Epilepsy; gamma-Aminobutyric Acid;

1985
The clinical physiology of side effects in long-term L-DOPA therapy.
    Advances in neurology, 1974, Volume: 5

    Topics: Acetylcholine; Basal Ganglia; Brain Chemistry; Brain Stem; Creatinine; Diagnosis, Differential; Dopa

1974

Trials

4 trials available for gamma-aminobutyric acid and Movement Disorders

ArticleYear
Gabapentin for painful legs and moving toes syndrome.
    European neurology, 2004, Volume: 51, Issue:3

    Topics: Acetates; Aged; Amines; Cyclohexanecarboxylic Acids; Electromyography; Excitatory Amino Acid Antagon

2004
Intermittent prednisolone and autoantibodies to GAD65 in juvenile neuronal ceroid lipofuscinosis.
    Neurology, 2008, Apr-01, Volume: 70, Issue:14

    Topics: Adolescent; Age Factors; Autoantibodies; Biomarkers; Brain; Child; Dose-Response Relationship, Drug;

2008
GABA and movement disorders.
    Advances in biochemical psychopharmacology, 1981, Volume: 30

    Topics: Anticonvulsants; Baclofen; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induced;

1981
Gabapentin and motor fluctuations in Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 1997, Volume: 12, Issue:4

    Topics: Acetates; Aged; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Drug Therapy, Combination

1997

Other Studies

48 other studies available for gamma-aminobutyric acid and Movement Disorders

ArticleYear
Mice with monoallelic
    Journal of neurophysiology, 2022, 03-01, Volume: 127, Issue:3

    Topics: Animals; Cerebellum; gamma-Aminobutyric Acid; GTP-Binding Protein alpha Subunits, Gi-Go; Mice; Movem

2022
Exercise enhances motor skill learning by neurotransmitter switching in the adult midbrain.
    Nature communications, 2020, 05-04, Volume: 11, Issue:1

    Topics: Acetylcholine; Animals; Female; gamma-Aminobutyric Acid; Learning; Male; Mesencephalon; Mice, Inbred

2020
Gamma-aminobutyric acid levels in cerebrospinal fluid in neuropaediatric disorders.
    Developmental medicine and child neurology, 2018, Volume: 60, Issue:8

    Topics: Adolescent; Adult; Biomarkers; Child; Child, Preschool; Cohort Studies; Epilepsy; Female; gamma-Amin

2018
Athetoid Movements as Initial Manifestation of Primary Sjögren Syndrome.
    Tremor and other hyperkinetic movements (New York, N.Y.), 2018, Volume: 8

    Topics: Aged; Amines; Anticonvulsants; Athetosis; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Ami

2018
The Influence of Primary Motor Cortex Inhibition on Upper Limb Impairment and Function in Chronic Stroke: A Multimodal Study.
    Neurorehabilitation and neural repair, 2019, Volume: 33, Issue:2

    Topics: Aged; Aged, 80 and over; Chronic Disease; Electromyography; Evoked Potentials, Motor; Female; gamma-

2019
Sensorimotor cortex gamma-aminobutyric acid concentration correlates with impaired performance in patients with MS.
    AJNR. American journal of neuroradiology, 2013, Volume: 34, Issue:9

    Topics: Adult; Biomarkers; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; M

2013
Grafted Neural Precursors Integrate Into Mouse Striatum, Differentiate and Promote Recovery of Function Through Release of Erythropoietin in MPTP-Treated Mice.
    ASN neuro, 2016, Volume: 8, Issue:5

    Topics: Animals; Antigens; Antigens, Neoplasm; Cell- and Tissue-Based Therapy; Choline O-Acetyltransferase;

2016
[Paroxysmal kinesigenic dyskinesia: a channelopathy? Study of 19 cases].
    Revue neurologique, 2009, Volume: 165, Issue:2

    Topics: Adolescent; Adult; Age of Onset; Amines; Anticonvulsants; Channelopathies; Child; Child, Preschool;

2009
Two novel comments on the treatment of Huntington's disease.
    The Journal of neuropsychiatry and clinical neurosciences, 2009,Winter, Volume: 21, Issue:1

    Topics: Basal Ganglia; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Huntington Disease; Models, Neurologi

2009
Hypoglycemia induced behavioural deficit and decreased GABA receptor, CREB expression in the cerebellum of streptozoticin induced diabetic rats.
    Brain research bulletin, 2010, Nov-20, Volume: 83, Issue:6

    Topics: Analysis of Variance; Animals; Cerebellum; CREB-Binding Protein; Diabetes Mellitus, Experimental; Di

2010
Altered spontaneous discharge rate and pattern of basal ganglia output neurons in the circling (ci2) rat mutant.
    Neuroscience, 2003, Volume: 118, Issue:3

    Topics: Action Potentials; Animals; Basal Ganglia; Basal Ganglia Diseases; Dopamine; Efferent Pathways; Fema

2003
The basement membrane components nidogen and type XVIII collagen regulate organization of neuromuscular junctions in Caenorhabditis elegans.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, May-01, Volume: 23, Issue:9

    Topics: Alleles; Animals; Basement Membrane; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calciu

2003
Sex differences in GABA(A)ergic system in rat substantia nigra pars reticulata.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2003, Volume: 21, Issue:5

    Topics: Age Factors; Animals; Cell Count; Female; gamma-Aminobutyric Acid; Immunohistochemistry; In Situ Hyb

2003
[GABOB IN PEDIATRICS. CLINICAL AND ELECTROENCEPHALOGRAPHIC STUDY OF 28 CASES].
    Minerva pediatrica, 1964, Jun-30, Volume: 16

    Topics: Adolescent; Aminobutyrates; Barbiturates; Brain Injuries; Cerebral Palsy; Child; Electroencephalogra

1964
Proton MR spectroscopy in succinic semialdehyde dehydrogenase deficiency.
    Neurology, 2004, Mar-23, Volume: 62, Issue:6

    Topics: Adult; Aldehyde Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Brain; gamma-Aminobutyric Aci

2004
UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2006, Volume: 16, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Arachidonic Acids; Brain Chemistry; D

2006
Progesterone attenuates neuroleptic-induced orofacial dyskinesia via the activity of its metabolite, allopregnanolone, a positive GABA(A) modulating neurosteroid.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Feb-15, Volume: 32, Issue:2

    Topics: Animals; Antipsychotic Agents; Brain Diseases; Control Groups; Disease Models, Animal; Dopamine; Dys

2008
Gamma-aminobutyric acid (GABA), Monograph.
    Alternative medicine review : a journal of clinical therapeutic, 2007, Volume: 12, Issue:3

    Topics: Anxiety; Depression; Epilepsy; GABA Agents; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives

2007
Impairment of movement-associated brain deactivation in multiple sclerosis: further evidence for a functional pathology of interhemispheric neuronal inhibition.
    Experimental brain research, 2008, Volume: 187, Issue:1

    Topics: Adult; Cerebral Cortex; Corpus Callosum; Female; gamma-Aminobutyric Acid; Hand; Humans; Magnetic Res

2008
Successful treatment of hemiballismus with progabide, a new GABA-mimetic agent.
    Journal of neurology, 1983, Volume: 229, Issue:2

    Topics: Aged; Brain; Female; gamma-Aminobutyric Acid; Humans; Movement Disorders; Thalamic Nuclei; Tomograph

1983
Pharmacological and therapeutic actions of GABA receptor agonists.
    Journal of neural transmission. Supplementum, 1983, Volume: 18

    Topics: Bipolar Disorder; Emotions; gamma-Aminobutyric Acid; Humans; Movement Disorders; Norepinephrine; Rec

1983
Reversal of akinesia and release of festination by morphine or GABA applied focally to the nucleus reticularis tegmenti pontis.
    Behavioral neuroscience, 1984, Volume: 98, Issue:4

    Topics: Animals; Depression, Chemical; gamma-Aminobutyric Acid; Haloperidol; Male; Morphine; Movement Disord

1984
Nonketotic hyperglycemia appearing as choreoathetosis or ballism.
    Archives of internal medicine, 1982, Volume: 142, Issue:1

    Topics: Aged; Athetosis; Basal Ganglia Diseases; Chorea; Female; gamma-Aminobutyric Acid; Humans; Hyperglyce

1982
Evidence for the participation of nigrotectal gamma-aminobutyrate-containing neurones in striatal and nigral-derived circling in the rat.
    Neuroscience, 1982, Volume: 7, Issue:1

    Topics: Animals; Brain Mapping; Corpus Striatum; gamma-Aminobutyric Acid; Male; Motor Activity; Movement Dis

1982
The subcortical regulatory motor system in the development and its disorders.
    Acta Universitatis Carolinae. Medica. Monographia, 1980, Volume: 96

    Topics: Cerebellum; Child; Child, Preschool; Corpus Striatum; gamma-Aminobutyric Acid; Humans; Infant; Infan

1980
Interactions of the subthalamic nucleus and the subpallidal area in oro-facial dyskinesia: role of GABA and glutamate.
    Psychopharmacology, 1995, Volume: 119, Issue:1

    Topics: Animals; Behavior, Animal; Cats; Facial Muscles; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamu

1995
Increased striatal glucose consumption in Sydenham's chorea.
    Movement disorders : official journal of the Movement Disorder Society, 1993, Volume: 8, Issue:4

    Topics: Adolescent; Aged; Basal Ganglia; Chorea; Corpus Striatum; Diagnosis, Differential; Dopamine; Female;

1993
Functional injury of cholinergic, GABAergic and dopaminergic systems in the basal ganglia of adult rat with kaolin-induced hydrocephalus.
    Brain research, 1997, Oct-03, Volume: 770, Issue:1-2

    Topics: Acetylcholine; Age Factors; Animals; Cell Count; Choline O-Acetyltransferase; Cholinergic Fibers; Do

1997
Alterations in spontaneous single unit activity of striatal subdivisions during ontogenesis in mutant dystonic hamsters.
    Brain research, 1999, Mar-13, Volume: 821, Issue:2

    Topics: Animals; Cricetinae; Disease Models, Animal; Dystonia; Electrophysiology; gamma-Aminobutyric Acid; M

1999
The 5HT(1B) receptor agonist, CP-93129, inhibits [(3)H]-GABA release from rat globus pallidus slices and reverses akinesia following intrapallidal injection in the reserpine-treated rat.
    British journal of pharmacology, 2000, Volume: 130, Issue:8

    Topics: Animals; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Globus Pallidus; In Vitro Techni

2000
Hemiballismus.
    The New England journal of medicine, 1977, Mar-31, Volume: 296, Issue:13

    Topics: Aminobutyrates; Diencephalon; gamma-Aminobutyric Acid; Humans; Huntington Disease; Movement Disorder

1977
Excitation-mediating and inhibition-mediating dopamine-receptors: a new concept towards a better understanding of electrophysiological, biochemical, pharmacological, functional and clinical data.
    Psychopharmacologia, 1976, Feb-02, Volume: 45, Issue:3

    Topics: Amphetamines; Animals; Apomorphine; Brain; Cats; Caudate Nucleus; Corpus Striatum; Dopamine; Electro

1976
Electrophysiology of Purkinje neurons in the weaver mouse: iontophoresis of neurotransmitters and cyclic nucleotides, and stimulation of the nucleus locus coeruleus.
    Brain research, 1976, Sep-10, Volume: 114, Issue:1

    Topics: Acetylcholine; Action Potentials; Animals; Cerebral Ventricles; Cyclic AMP; Cyclic GMP; Electrophysi

1976
Gabaminergic and serotonergic modulation of the antidyskinetic effects of tiapride and oxiperomide in the model using 2-(N,N-dipropyl)animo-5,6-dihydroxytetralin.
    European journal of pharmacology, 1978, Jun-15, Volume: 49, Issue:4

    Topics: 2-Naphthylamine; Aminobutyrates; Animals; Behavior, Animal; Benzamides; Benzimidazoles; Disease Mode

1978
Role of thalamic gamma-aminobutyrate in motor functions: catalepsy and ipsiversive turning after intrathalamic muscimol.
    Neuroscience, 1979, Volume: 4, Issue:10

    Topics: Animals; Brain Mapping; Catalepsy; Corpus Striatum; gamma-Aminobutyric Acid; Humans; Male; Motor Act

1979
A case of adult onset pure pallidal degeneration. II. Analysis of neurotransmitter markers, with special reference to the termination of pallidothalamic tract in human brain.
    Journal of the neurological sciences, 1991, Volume: 102, Issue:1

    Topics: Adult; Aged; Basal Ganglia Diseases; Biomarkers; Brain Chemistry; Choline O-Acetyltransferase; Femal

1991
Oro-facial dyskinesia and the sub-commissural part of the globus pallidus in the cat: role of acetylcholine and its interaction with GABA.
    Psychopharmacology, 1989, Volume: 99, Issue:3

    Topics: Acetylcholine; Animals; Behavior, Animal; Carbachol; Cats; Enkephalins; gamma-Aminobutyric Acid; Glo

1989
Intrathecal GABA, glycine, taurine or beta-alanine elicits dyskinetic movements in mice.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:2

    Topics: Alanine; Animals; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glycine; Injections, In

1989
[Choreo-ballistic status treated by GABA].
    No to hattatsu = Brain and development, 1989, Volume: 21, Issue:5

    Topics: Child; Chorea; Female; gamma-Aminobutyric Acid; Humans; Movement Disorders

1989
Striatal neurochemical changes and motor dysfunction in mipafox-treated animals.
    Methods and findings in experimental and clinical pharmacology, 1985, Volume: 7, Issue:2

    Topics: Acetylcholinesterase; Animals; Carboxylic Ester Hydrolases; Corpus Striatum; Dopamine; gamma-Aminobu

1985
Chemical and structural changes in the brain in patients with movement disorder.
    Psychopharmacology. Supplementum, 1985, Volume: 2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Antipsychotic Agents; Brain; Choline O-Acetyltransfer

1985
[The electrophysiological approach to tardive dyskinesias].
    L'Encephale, 1988, Volume: 14 Spec No

    Topics: Diagnosis, Differential; Dopamine Agents; Dyskinesia, Drug-Induced; Electromyography; gamma-Aminobut

1988
[Progabide treatment of a case of the syndrome of painful legs and moving toes].
    Revue neurologique, 1985, Volume: 141, Issue:5

    Topics: Adult; Female; gamma-Aminobutyric Acid; Humans; Leg; Middle Aged; Movement Disorders; Pain; Receptor

1985
Dopamine-GABA interactions: evidence that GABA transmits, modulates and mediates dopaminergic functions in the basal ganglia and the limbic system.
    Acta neurologica Scandinavica. Supplementum, 1986, Volume: 107

    Topics: Amygdala; Animals; Basal Ganglia; Behavior, Animal; Benzodiazepines; Catalepsy; Corpus Striatum; Dop

1986
A simple model of the interactions of dopamine, acetylcholine and GABA in movement disorders seen in psychiatry.
    Medical hypotheses, 1988, Volume: 27, Issue:4

    Topics: Acetylcholine; Basal Ganglia; Dopamine; gamma-Aminobutyric Acid; Humans; Models, Psychological; Move

1988
[Hemiballism and its treatment].
    Harefuah, 1987, Dec-15, Volume: 113, Issue:12

    Topics: Cerebrovascular Disorders; Dopamine Antagonists; gamma-Aminobutyric Acid; Humans; Movement Disorders

1987
Gamma-vinyl-GABA treatment of tardive dyskinesia and other movement disorders.
    Biological psychiatry, 1985, Volume: 20, Issue:8

    Topics: Adult; Aged; Aminocaproates; Confusion; Dyskinesia, Drug-Induced; Female; gamma-Aminobutyric Acid; H

1985
[Effects of 4-(o-benzylphenoxy)-N-methylbutylamine hydrochloride (MCI-2016, bifemelane hydrochloride) on spontaneous motor activity under different experimental conditions].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 86, Issue:1

    Topics: Animals; Benzhydryl Compounds; Brain Injuries; gamma-Aminobutyric Acid; Hypoxia, Brain; Male; Metham

1985