gamma-aminobutyric acid has been researched along with Motor Neuron Disease in 4 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Motor Neuron Disease: Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The first clinical trials in spinal muscular atrophy are currently underway." | 2.40 | Carrell-Krusen Symposium invited lecture. Clinical trials in motor neuron diseases. ( Miller, RG, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bonanno, G | 1 |
| Fumagalli, E | 1 |
| Milanese, M | 1 |
| Zappettini, S | 1 |
| Mennini, T | 1 |
| Wittstock, M | 1 |
| Wolters, A | 1 |
| Benecke, R | 1 |
| Miller, RG | 1 |
| de Carvalho, M | 1 |
1 review available for gamma-aminobutyric acid and Motor Neuron Disease
| Article | Year |
|---|---|
Carrell-Krusen Symposium invited lecture. Clinical trials in motor neuron diseases.
Topics: Acetates; Adolescent; Adult; Amines; Amyotrophic Lateral Sclerosis; Animals; Brain-Derived Neurotrop | 1999 |
3 other studies available for gamma-aminobutyric acid and Motor Neuron Disease
| Article | Year |
|---|---|
Release of [3H]D-aspartate induced by K+-stimulation is increased in the cervical spinal cord of the wobbler mouse: a model of motor neuron disease.
Topics: Animals; Aspartic Acid; Cervical Vertebrae; Disease Models, Animal; gamma-Aminobutyric Acid; Mice; M | 2009 |
Transcallosal inhibition in amyotrophic lateral sclerosis.
Topics: Aged; Amyotrophic Lateral Sclerosis; Corpus Callosum; Evoked Potentials, Motor; Female; gamma-Aminob | 2007 |
Gabapentin for the treatment of spasticity in patients with amyotrophic lateral sclerosis.
Topics: Acetates; Aged; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hu | 2001 |