gamma-aminobutyric acid has been researched along with Morphine Abuse in 38 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metabolic consequences of morphine dependence and withdrawal intervention have not been well explored." | 7.78 | ¹H NMR-based metabonomic analysis of brain in rats of morphine dependence and withdrawal intervention. ( Bu, Q; Cen, X; Deng, P; Deng, Y; Hu, C; Hu, Z; Li, Y; Shao, X; Xu, Y; Yan, G; Zhao, J; Zhao, Y; Zhou, J; Zhu, R, 2012) |
| "To observe the effects of gamma-aminobutyric acid (GABA) on the electric activities of pain-excited neurons (PEN) in nucleus accumbens (NAc) in central nervous system (CNS) of morphine-dependent rats." | 7.74 | Modulation of gamma-aminobutyric acid on painful sense in central nervous system of morphine-dependent rats. ( Li, X; Xu, MY; Xu, Y, 2008) |
| "After GABA or the GABA(A)-receptor antagonist, bicuculline (Bic), was injected into cerebral ventricles or NAc, right sciatic nerve was stimulated by electrical pulses, which was considered as traumatic pain stimulation." | 7.74 | Modulation of gamma-aminobutyric acid on painful sense in central nervous system of morphine-dependent rats. ( Li, X; Xu, MY; Xu, Y, 2008) |
| "Metabolic consequences of morphine dependence and withdrawal intervention have not been well explored." | 3.78 | ¹H NMR-based metabonomic analysis of brain in rats of morphine dependence and withdrawal intervention. ( Bu, Q; Cen, X; Deng, P; Deng, Y; Hu, C; Hu, Z; Li, Y; Shao, X; Xu, Y; Yan, G; Zhao, J; Zhao, Y; Zhou, J; Zhu, R, 2012) |
| "To observe the effects of gamma-aminobutyric acid (GABA) on the electric activities of pain-excited neurons (PEN) in nucleus accumbens (NAc) in central nervous system (CNS) of morphine-dependent rats." | 3.74 | Modulation of gamma-aminobutyric acid on painful sense in central nervous system of morphine-dependent rats. ( Li, X; Xu, MY; Xu, Y, 2008) |
| "After GABA or the GABA(A)-receptor antagonist, bicuculline (Bic), was injected into cerebral ventricles or NAc, right sciatic nerve was stimulated by electrical pulses, which was considered as traumatic pain stimulation." | 3.74 | Modulation of gamma-aminobutyric acid on painful sense in central nervous system of morphine-dependent rats. ( Li, X; Xu, MY; Xu, Y, 2008) |
| "6-fold shift in morphine's dose-response curve." | 1.33 | Attenuation of morphine tolerance by intrathecal gabapentin is associated with suppression of morphine-evoked excitatory amino acid release in the rat spinal cord. ( Lee, MS; Lin, JA; Lin, SL; Wen, ZH; Wong, CS; Wu, CT; Yeh, CC, 2005) |
| "Morphine addiction has been shown to result from neural adaptations produced by repeated drug exposure, but the mechanism is still unclear." | 1.32 | Decrease of morphine-induced reward effects and withdrawal symptoms in mice overexpressing gamma-aminobutyric acid transporter I. ( Fei, J; Guo, LH; Hu, JH; Jiang, J; Ma, YH; Mei, ZT; Yang, N; Zhang, XY; Zhou, XG, 2003) |
| "Morphine dependence was assessed with naltrexone." | 1.26 | The influence of a GABA transaminase inhibitor, gamma-vinyl GABA, on voluntary morphine consumption in the rat. ( Buckett, WR, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (39.47) | 18.7374 |
| 1990's | 5 (13.16) | 18.2507 |
| 2000's | 10 (26.32) | 29.6817 |
| 2010's | 7 (18.42) | 24.3611 |
| 2020's | 1 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Davoudi, M | 1 |
| Vijeepallam, K | 1 |
| Azizi, H | 1 |
| Mirnajafi-Zadeh, J | 1 |
| Semnanian, S | 1 |
| Luster, BR | 1 |
| Cogan, ES | 1 |
| Schmidt, KT | 1 |
| Pati, D | 1 |
| Pina, MM | 1 |
| Dange, K | 1 |
| McElligott, ZA | 1 |
| Hasanein, P | 1 |
| Shakeri, S | 1 |
| Lee, BH | 1 |
| Zhao, RJ | 1 |
| Lee, BG | 1 |
| Kim, NJ | 1 |
| Yang, CH | 1 |
| Kim, HY | 1 |
| Gwak, YS | 1 |
| Lim, SC | 1 |
| Kim, JS | 1 |
| Lee, YK | 1 |
| Lee, HJ | 1 |
| Zhang, L | 1 |
| Cui, Y | 1 |
| Wang, YC | 1 |
| Yin, H | 1 |
| Zheng, JM | 1 |
| Huang, L | 1 |
| Zhao, ZW | 1 |
| Li, J | 1 |
| Liu, QF | 1 |
| Li, L | 1 |
| Guo, YQ | 1 |
| Li, X | 2 |
| Mou, ZD | 1 |
| Wang, X | 1 |
| Du, GZ | 1 |
| Xu, Y | 2 |
| Xu, MY | 1 |
| Lelevich, SV | 1 |
| Lelevich, VV | 1 |
| Novokshonov, AA | 1 |
| Madhavan, A | 1 |
| He, L | 1 |
| Stuber, GD | 1 |
| Bonci, A | 1 |
| Whistler, JL | 1 |
| Hu, Z | 1 |
| Deng, Y | 1 |
| Hu, C | 1 |
| Deng, P | 1 |
| Bu, Q | 1 |
| Yan, G | 1 |
| Zhou, J | 1 |
| Shao, X | 1 |
| Zhao, J | 1 |
| Li, Y | 1 |
| Zhu, R | 1 |
| Zhao, Y | 1 |
| Cen, X | 1 |
| Hack, SP | 1 |
| Vaughan, CW | 1 |
| Christie, MJ | 1 |
| Hu, JH | 1 |
| Yang, N | 1 |
| Ma, YH | 1 |
| Zhou, XG | 1 |
| Zhang, XY | 1 |
| Jiang, J | 1 |
| Mei, ZT | 1 |
| Fei, J | 1 |
| Guo, LH | 1 |
| Leventhal, L | 1 |
| Cosmi, S | 1 |
| Deecher, D | 1 |
| Lin, JA | 1 |
| Lee, MS | 1 |
| Wu, CT | 1 |
| Yeh, CC | 1 |
| Lin, SL | 1 |
| Wen, ZH | 1 |
| Wong, CS | 1 |
| Dunbar, SA | 1 |
| Karamian, I | 1 |
| Yeatman, A | 1 |
| Zhang, J | 1 |
| DeFeudis, FV | 1 |
| Smith, JE | 1 |
| Co, C | 1 |
| Freeman, ME | 1 |
| Sands, MP | 1 |
| Lane, JD | 1 |
| Ticku, MK | 1 |
| Huffman, RD | 1 |
| Sivam, SP | 1 |
| Ho, IK | 1 |
| van der Laan, JW | 2 |
| Jacobs, AW | 1 |
| Bruinvels, J | 2 |
| Buckett, WR | 3 |
| Suzuki, T | 2 |
| Tsuda, M | 1 |
| Narita, M | 1 |
| Funada, M | 1 |
| Mizoguchi, H | 1 |
| Misawa, M | 1 |
| Varani, K | 1 |
| Beani, L | 2 |
| Bianchi, C | 2 |
| Borea, PA | 1 |
| Simonato, M | 2 |
| Sayin, U | 1 |
| Atasoy, S | 1 |
| Uzbay, IT | 1 |
| Aricioğlu-Kartal, F | 1 |
| Koyuncuoğlu, H | 1 |
| Zarrindast, MR | 1 |
| Mousa-Ahmadi, E | 1 |
| Schoffelmeer, AN | 1 |
| Wardeh, G | 1 |
| Vanderschuren, LJ | 1 |
| Heikkilä, AT | 1 |
| Echenko, O | 1 |
| Uusi-Oukari, M | 1 |
| Sinkkonen, ST | 1 |
| Korpi, ER | 1 |
| Volicer, L | 1 |
| Puri, SK | 1 |
| Choma, P | 1 |
| Rix, KJ | 1 |
| Davidson, N | 1 |
| Kuriyama, K | 1 |
| Yoneda, Y | 1 |
| Davies, J | 1 |
| Uebersax, R | 1 |
| Ruetsch, YA | 1 |
| Rönnbäck, L | 1 |
| Hansson, E | 1 |
| Cupello, A | 1 |
| Rapallino, MV | 1 |
| Zeuchner, J | 1 |
| Rosengren, L | 1 |
| Antonelli, T | 1 |
| Rando, S | 1 |
| Tanganelli, S | 1 |
2 reviews available for gamma-aminobutyric acid and Morphine Abuse
| Article | Year |
|---|---|
[Modification of morphine dependence under chronic pain and its mechanism].
Topics: Animals; Brain; Chronic Disease; gamma-Aminobutyric Acid; Male; Morphine Dependence; Pain; Rats; Rat | 2001 |
gamma-aminobutyric acid in alcohol, barbiturate and morphine dependence: a review.
Topics: Alcoholism; Aminobutyrates; Animals; Barbiturates; Brain; Ethanol; gamma-Aminobutyric Acid; Humans; | 1977 |
36 other studies available for gamma-aminobutyric acid and Morphine Abuse
| Article | Year |
|---|---|
PKC inhibitor reversed the suppressive effect of orexin-A on IPSCs of locus coeruleus neurons in naloxone-induced morphine withdrawal.
Topics: Animals; gamma-Aminobutyric Acid; Indoles; Inhibitory Postsynaptic Potentials; Locus Coeruleus; Male | 2019 |
Inhibitory transmission in the bed nucleus of the stria terminalis in male and female mice following morphine withdrawal.
Topics: Analgesics, Opioid; Animals; Female; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Ma | 2020 |
Pregabalin role in inhibition of morphine analgesic tolerance and physical dependency in rats.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Toleranc | 2014 |
Acupuncture Suppresses Morphine Craving in Progressive Ratio Through the GABA System.
Topics: Acupuncture Points; Acupuncture Therapy; Animals; Craving; gamma-Aminobutyric Acid; Humans; Male; Mo | 2015 |
RETRACTED: Exploring the mechanism by which accumbal deep brain stimulation attenuates morphine-induced reinstatement through manganese-enhanced MRI and pharmacological intervention.
Topics: Animals; Conditioning, Operant; Contrast Media; Deep Brain Stimulation; GABA Antagonists; gamma-Amin | 2017 |
Injection of Toll-like receptor 4 siRNA into the ventrolateral periaqueductal gray attenuates withdrawal syndrome in morphine-dependent rats.
Topics: Animals; Blotting, Western; Chromatography, High Pressure Liquid; Disease Models, Animal; Enzyme-Lin | 2016 |
Modulation of gamma-aminobutyric acid on painful sense in central nervous system of morphine-dependent rats.
Topics: Action Potentials; Animals; Bicuculline; Disease Models, Animal; Drug Administration Schedule; Elect | 2008 |
Neurotransmitter mechanisms of morphine withdrawal syndrome.
Topics: Animals; Brain Stem; Cerebellum; Chromatography, High Pressure Liquid; Dopamine; gamma-Aminobutyric | 2009 |
micro-Opioid receptor endocytosis prevents adaptations in ventral tegmental area GABA transmission induced during naloxone-precipitated morphine withdrawal.
Topics: Adaptation, Physiological; Animals; Chimera; Cyclic AMP; Disease Models, Animal; Endocytosis; gamma- | 2010 |
¹H NMR-based metabonomic analysis of brain in rats of morphine dependence and withdrawal intervention.
Topics: Animals; Brain; Energy Metabolism; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Magnetic Reson | 2012 |
Modulation of GABA release during morphine withdrawal in midbrain neurons in vitro.
Topics: Action Potentials; Adenosine; Affinity Labels; Animals; Colforsin; Cyclic AMP; Dipyridamole; Dose-Re | 2003 |
Decrease of morphine-induced reward effects and withdrawal symptoms in mice overexpressing gamma-aminobutyric acid transporter I.
Topics: Adaptation, Physiological; Animals; Brain; Carrier Proteins; Conditioning, Psychological; GABA Antag | 2003 |
Effect of calcium channel modulators on temperature regulation in ovariectomized rats.
Topics: Amines; Animals; Body Temperature Regulation; Calcium Channel Blockers; Calcium Channels; Cyclohexan | 2005 |
Attenuation of morphine tolerance by intrathecal gabapentin is associated with suppression of morphine-evoked excitatory amino acid release in the rat spinal cord.
Topics: Amines; Analgesics; Analysis of Variance; Animals; Cyclohexanecarboxylic Acids; Drug Interactions; D | 2005 |
Effects of recurrent withdrawal on spinal GABA release during chronic morphine infusion in the rat.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; gamma-Aminobutyric Acid; Glutamates; Infusion Pum | 2006 |
gamma-Aminobutyric acid-ergic analgesia: implications for gamma-aminobutyric acid-ergic therapy for drug addictions.
Topics: Animals; Baclofen; Brain; Drug Tolerance; Endorphins; GABA Antagonists; gamma-Aminobutyric Acid; Hum | 1984 |
Neurotransmitter turnover in rat striatum is correlated with morphine self-administration.
Topics: Animals; Aspartic Acid; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Glutamates; Glycine; Hum | 1980 |
The effects of acute and chronic morphine administration on GABA receptor binding.
Topics: Animals; Binding Sites; Brain; gamma-Aminobutyric Acid; Humans; Male; Morphine; Morphine Dependence; | 1980 |
Influence of morphine dependence on GABA-stimulated benzodiazepine binding to mouse brain synaptic membranes.
Topics: Animals; Brain; Flunitrazepam; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Kinetics; Male; | 1982 |
Effects of branched-chain fatty acids on GABA-degradation and behavior: further evidence for a role of GABA in quasi-morphine abstinence behavior.
Topics: 4-Aminobutyrate Transaminase; Animals; Behavior, Animal; Brain Chemistry; Caproates; Dose-Response R | 1980 |
A dual role for GABA in quasi-morphine abstinence behavior induced by di-n-propylacetate involving both initiation and termination.
Topics: Animals; Behavior, Animal; Drug Tolerance; gamma-Aminobutyric Acid; Humans; Hydroxylation; Male; Mor | 1981 |
The influence of a GABA transaminase inhibitor, gamma-vinyl GABA, on voluntary morphine consumption in the rat.
Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Animals; Brain; gamma-Aminobutyric Acid; Humans; Male; | 1981 |
Irreversible inhibitors of GABA transaminase induce antinociceptive effects and potentiate morphine.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Ataxia; Brain Chemistry; Drug Synerg | 1980 |
Diazepam pretreatment suppresses morphine withdrawal signs in the mouse.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Anti-Anxiety Agents; Anticonvulsants; Cerebr | 1996 |
Changes in [3H]-UK 14304 binding to alpha 2-adrenoceptors in morphine-dependent guinea-pigs.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cerebral Cortex; Dose-Response Relationshi | 1995 |
Gamma-vinyl-GABA potentiates the severity of naloxone-precipitated abstinence signs in morphine-dependent rats.
Topics: Animals; Anticonvulsants; Drug Synergism; gamma-Aminobutyric Acid; Male; Morphine Dependence; Naloxo | 1998 |
Effects of GABAergic system on naloxone-induced jumping in morphine-dependent mice.
Topics: Animals; Baclofen; Behavior, Animal; Bicuculline; GABA Agonists; GABA Antagonists; GABA-A Receptor A | 1999 |
Morphine acutely and persistently attenuates nonvesicular GABA release in rat nucleus accumbens.
Topics: Analgesics; Animals; Benzeneacetamides; Carrier Proteins; Dopamine; Dose-Response Relationship, Drug | 2001 |
Morphine withdrawal increases expression of GABA(A) receptor epsilon subunit mRNA in locus coeruleus neurons.
Topics: Animals; Drug Interactions; gamma-Aminobutyric Acid; Gene Expression; Locus Coeruleus; Male; Morphin | 2001 |
Cyclic GMP and GABA levels in rat striatum and cerebellum during morphine withdrawal: effect of apomorphine.
Topics: Aminobutyrates; Animals; Apomorphine; Brain Chemistry; Cerebellum; Corpus Striatum; Cyclic GMP; gamm | 1977 |
The influence of morphine dependence on some specific effects mediated by monoaminergic and GABAergic systems.
Topics: Animals; Apomorphine; Biogenic Amines; Body Temperature; Dopamine; gamma-Aminobutyric Acid; Humans; | 1979 |
Morphine induced alterations of gamma-aminobutyric acid and taurine contents and L-glutamate decarboxylase activity in rat spinal cord and thalamus: possible correlates with analgesic action of morphine.
Topics: Aminobutyrates; Analgesia; Animals; Carboxy-Lyases; Cerebral Aqueduct; gamma-Aminobutyric Acid; Gang | 1978 |
Effects of morphine and naloxone on Renshaw cells and spinal interneurones in morphine dependent and non-dependent rats.
Topics: Acetylcholine; Animals; Dextrorphan; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glycine | 1976 |
[Alcoholism: is there a rational explanation for and a specific treatment of the alcohol-dependent patient?].
Topics: Alcoholism; gamma-Aminobutyric Acid; Humans; Models, Biological; Morphine Dependence | 1990 |
Neurotransmitter uptake in various brain regions of chronically morphinized rats.
Topics: Administration, Oral; Animals; Brain; Brain Stem; Cerebral Cortex; Corpus Striatum; gamma-Aminobutyr | 1986 |
Cortical acetylcholine release is increased and gamma-aminobutyric acid outflow is reduced during morphine withdrawal.
Topics: Acetylcholine; Animals; Atropine; Cerebral Cortex; Diazepam; Female; gamma-Aminobutyric Acid; Guinea | 1986 |