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gamma-aminobutyric acid and Metabolic Syndrome

gamma-aminobutyric acid has been researched along with Metabolic Syndrome in 8 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Metabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state.

Research Excerpts

ExcerptRelevanceReference
"In this study, gamma-aminobutyric acid (GABA) enriched rice bran (ERB) was supplemented to obese rats to investigate the attenuation of metabolic syndromes induced by high-fat diet."7.88Gamma-aminobutyric Acid Enriched Rice Bran Diet Attenuates Insulin Resistance and Balances Energy Expenditure via Modification of Gut Microbiota and Short-Chain Fatty Acids. ( Blanchard, C; Lam, SM; Shang, W; Shui, G; Si, X; Strappe, P; Zhou, Z, 2018)
" High-energy diet, saturated fats and trans-fats during perinatal period could suppress Delta(6) and Delta(5) desaturases both in the maternal and fetal tissues, resulting in a decrease in the concentrations of long-chain polyunsaturated fatty acids (LCPUFAs): arachidonic acid (AA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) that have a negative feedback control on inflammation."4.84Is metabolic syndrome X a disorder of the brain with the initiation of low-grade systemic inflammatory events during the perinatal period? ( Das, UN, 2007)
"In this study, gamma-aminobutyric acid (GABA) enriched rice bran (ERB) was supplemented to obese rats to investigate the attenuation of metabolic syndromes induced by high-fat diet."3.88Gamma-aminobutyric Acid Enriched Rice Bran Diet Attenuates Insulin Resistance and Balances Energy Expenditure via Modification of Gut Microbiota and Short-Chain Fatty Acids. ( Blanchard, C; Lam, SM; Shang, W; Shui, G; Si, X; Strappe, P; Zhou, Z, 2018)
"This suggests that metabolic syndrome X could be a disorder of the brain due to suboptimal LCPUFAs during perinatal period that triggers low-grade systemic inflammation, implying that perinatal strategies are needed to prevent its development."2.44Is metabolic syndrome X a disorder of the brain with the initiation of low-grade systemic inflammatory events during the perinatal period? ( Das, UN, 2007)
"Metabolic syndrome is a cluster of risk factors including insulin resistance and type 2 diabetes and is found to associate partly with chronic stress at work in human."1.37Oral administration of γ-aminobutyric acid and γ-oryzanol prevents stress-induced hypoadiponectinemia. ( Hori, M; Kanemoto, S; Kiyotani, Y; Maehara, H; Nagasaka, R; Ohara, K; Uchida, A; Ushio, H, 2011)
"Metabolic syndrome is characterized by obesity, elevated blood pressure (BP), insulin resistance, and hypercholesterolemia."1.34Upregulation of GAD65 mRNA in the medulla of the rat model of metabolic syndrome. ( Akil, H; Britton, SL; Buck, BJ; Burghardt, PR; Kerman, IA; Koch, LG; Watson, SJ, 2007)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's5 (62.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Patterson, E1
Ryan, PM1
Wiley, N1
Carafa, I1
Sherwin, E1
Moloney, G1
Franciosi, E1
Mandal, R1
Wishart, DS1
Tuohy, K1
Ross, RP1
Cryan, JF1
Dinan, TG1
Stanton, C1
Jialal, I2
Patel, A1
Devaraj, S1
Adams-Huet, B1
Kootte, RS1
Levin, E1
Salojärvi, J1
Smits, LP1
Hartstra, AV1
Udayappan, SD1
Hermes, G1
Bouter, KE1
Koopen, AM1
Holst, JJ1
Knop, FK1
Blaak, EE1
Zhao, J1
Smidt, H1
Harms, AC1
Hankemeijer, T1
Bergman, JJGHM1
Romijn, HA1
Schaap, FG1
Olde Damink, SWM1
Ackermans, MT1
Dallinga-Thie, GM1
Zoetendal, E1
de Vos, WM1
Serlie, MJ1
Stroes, ESG1
Groen, AK1
Nieuwdorp, M1
Si, X1
Shang, W1
Zhou, Z1
Shui, G1
Lam, SM1
Blanchard, C1
Strappe, P1
Shim, K1
Gulhar, R1
Ohara, K1
Kiyotani, Y1
Uchida, A1
Nagasaka, R1
Maehara, H1
Kanemoto, S1
Hori, M1
Ushio, H1
Das, UN1
Buck, BJ1
Kerman, IA1
Burghardt, PR1
Koch, LG1
Britton, SL1
Akil, H1
Watson, SJ1

Reviews

1 review available for gamma-aminobutyric acid and Metabolic Syndrome

ArticleYear
Is metabolic syndrome X a disorder of the brain with the initiation of low-grade systemic inflammatory events during the perinatal period?
    The Journal of nutritional biochemistry, 2007, Volume: 18, Issue:11

    Topics: Animals; Appetite Regulation; Arachidonic Acid; Brain; Diabetes Mellitus, Type 2; Docosahexaenoic Ac

2007

Other Studies

7 other studies available for gamma-aminobutyric acid and Metabolic Syndrome

ArticleYear
Gamma-aminobutyric acid-producing lactobacilli positively affect metabolism and depressive-like behaviour in a mouse model of metabolic syndrome.
    Scientific reports, 2019, 11-08, Volume: 9, Issue:1

    Topics: Adipose Tissue; Animals; Behavior, Animal; Body Weight; Cholesterol; Corticosterone; Depression; Dis

2019
Metabolites that activate the inflammasome in nascent metabolic syndrome.
    Journal of diabetes and its complications, 2021, Volume: 35, Issue:3

    Topics: Adult; Carnitine; Caspase 1; Diabetes Mellitus, Type 2; gamma-Aminobutyric Acid; Humans; Inflammasom

2021
Improvement of Insulin Sensitivity after Lean Donor Feces in Metabolic Syndrome Is Driven by Baseline Intestinal Microbiota Composition.
    Cell metabolism, 2017, Oct-03, Volume: 26, Issue:4

    Topics: Blood Glucose; Fecal Microbiota Transplantation; Feces; gamma-Aminobutyric Acid; Gastrointestinal Mi

2017
Gamma-aminobutyric Acid Enriched Rice Bran Diet Attenuates Insulin Resistance and Balances Energy Expenditure via Modification of Gut Microbiota and Short-Chain Fatty Acids.
    Journal of agricultural and food chemistry, 2018, Jan-31, Volume: 66, Issue:4

    Topics: Adipose Tissue; Animals; Ceramides; Diet; Diet, High-Fat; DNA; Energy Metabolism; Fatty Acids, Volat

2018
Exploratory metabolomics of nascent metabolic syndrome.
    Journal of diabetes and its complications, 2019, Volume: 33, Issue:3

    Topics: Adult; Aged; Biomarkers; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Female; gamma-Amino

2019
Oral administration of γ-aminobutyric acid and γ-oryzanol prevents stress-induced hypoadiponectinemia.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2011, Jun-15, Volume: 18, Issue:8-9

    Topics: Adiponectin; Administration, Oral; Animals; Anti-Obesity Agents; gamma-Aminobutyric Acid; Humans; Ma

2011
Upregulation of GAD65 mRNA in the medulla of the rat model of metabolic syndrome.
    Neuroscience letters, 2007, May-29, Volume: 419, Issue:2

    Topics: Animals; Autonomic Pathways; Cardiovascular Physiological Phenomena; Cardiovascular System; Disease

2007