gamma-aminobutyric acid has been researched along with MPTP Neurotoxicity Syndrome in 11 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The caffeine pretreatment showed significant protection against the reduction of paw grip strength in MPTP treated mice." | 1.43 | Neuroprotective effects of caffeine in MPTP model of Parkinson's disease: A (13)C NMR study. ( Bagga, P; Chugani, AN; Patel, AB, 2016) |
| " We conclude that endogenous N/OFQ functionally opposes DOP transmission in substantia nigra reticulata and that NOP receptor antagonists might be used in combination with DOP receptor agonists to reduce their dosage while maintaining their full therapeutic efficacy." | 1.40 | Stimulation of δ opioid receptor and blockade of nociceptin/orphanin FQ receptor synergistically attenuate parkinsonism. ( Ledonne, A; Mabrouk, OS; Mercuri, N; Morari, M; Viaro, R; Volta, M, 2014) |
| " On day 10, the locomotor response to L-dopa was significantly potentiated by chronic administration of idazoxan." | 1.31 | Noradrenoceptor antagonism with idazoxan improves L-dopa-induced dyskinesias in MPTP monkeys. ( Bédard, PJ; Doan, VD; Grondin, R; Hadj Tahar, A; Ladure, P, 2000) |
| "Treatment of Parkinson's disease with L-dopa is plagued in a majority of patients by dyskinesias." | 1.31 | Noradrenoceptor antagonism with idazoxan improves L-dopa-induced dyskinesias in MPTP monkeys. ( Bédard, PJ; Doan, VD; Grondin, R; Hadj Tahar, A; Ladure, P, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, D | 1 |
| Liu, Q | 1 |
| Jia, D | 1 |
| Dou, D | 1 |
| Wang, X | 1 |
| Kang, T | 1 |
| Mabrouk, OS | 1 |
| Viaro, R | 1 |
| Volta, M | 1 |
| Ledonne, A | 1 |
| Mercuri, N | 1 |
| Morari, M | 1 |
| Bagga, P | 1 |
| Chugani, AN | 1 |
| Patel, AB | 1 |
| Carelli, S | 1 |
| Giallongo, T | 1 |
| Viaggi, C | 1 |
| Gombalova, Z | 1 |
| Latorre, E | 1 |
| Mazza, M | 1 |
| Vaglini, F | 1 |
| Di Giulio, AM | 1 |
| Gorio, A | 1 |
| Xiao, YL | 1 |
| Fu, JM | 1 |
| Dong, Z | 1 |
| Yang, JQ | 1 |
| Zeng, FX | 1 |
| Zhu, LX | 1 |
| He, BC | 1 |
| Soares, J | 1 |
| Kliem, MA | 1 |
| Betarbet, R | 1 |
| Greenamyre, JT | 1 |
| Yamamoto, B | 1 |
| Wichmann, T | 1 |
| van der Stelt, M | 1 |
| Fox, SH | 1 |
| Hill, M | 1 |
| Crossman, AR | 1 |
| Petrosino, S | 1 |
| Di Marzo, V | 1 |
| Brotchie, JM | 1 |
| Levy, R | 2 |
| Herrero, MT | 2 |
| Ruberg, M | 2 |
| Villares, J | 1 |
| Faucheux, B | 2 |
| Guridi, J | 2 |
| Guillen, J | 2 |
| Luquin, MR | 2 |
| Javoy-Agid, F | 2 |
| Obeso, JA | 2 |
| Vila, M | 1 |
| Agid, Y | 1 |
| Hirsch, EC | 1 |
| Grondin, R | 1 |
| Hadj Tahar, A | 1 |
| Doan, VD | 1 |
| Ladure, P | 1 |
| Bédard, PJ | 1 |
| Snyder, SH | 1 |
11 other studies available for gamma-aminobutyric acid and MPTP Neurotoxicity Syndrome
| Article | Year |
|---|---|
Protective effect of arctigenin against MPP+ and MPTP-induced neurotoxicity.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; bcl-2-Associated X Protein; Behavior, Animal; Brain | 2014 |
Stimulation of δ opioid receptor and blockade of nociceptin/orphanin FQ receptor synergistically attenuate parkinsonism.
Topics: Animals; Benzamides; Benzimidazoles; Corpus Striatum; Dopaminergic Neurons; Drug Synergism; gamma-Am | 2014 |
Neuroprotective effects of caffeine in MPTP model of Parkinson's disease: A (13)C NMR study.
Topics: Amino Acids; Animals; Behavior, Animal; Brain; Caffeine; gamma-Aminobutyric Acid; Glucose; Hand Stre | 2016 |
Grafted Neural Precursors Integrate Into Mouse Striatum, Differentiate and Promote Recovery of Function Through Release of Erythropoietin in MPTP-Treated Mice.
Topics: Animals; Antigens; Antigens, Neoplasm; Cell- and Tissue-Based Therapy; Choline O-Acetyltransferase; | 2016 |
Neuroprotective mechanism of modafinil on Parkinson disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Topics: Animals; Benzhydryl Compounds; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Male; Mice; Mice, | 2004 |
Role of external pallidal segment in primate parkinsonism: comparison of the effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism and lesions of the external pallidal segment.
Topics: Action Potentials; Animals; Basal Ganglia; Behavior, Animal; gamma-Aminobutyric Acid; Globus Pallidu | 2004 |
A role for endocannabinoids in the generation of parkinsonism and levodopa-induced dyskinesia in MPTP-lesioned non-human primate models of Parkinson's disease.
Topics: Animals; Arachidonic Acids; Callithrix; Cannabinoid Receptor Modulators; Dyskinesia, Drug-Induced; E | 2005 |
Effects of nigrostriatal denervation and L-dopa therapy on the GABAergic neurons in the striatum in MPTP-treated monkeys and Parkinson's disease: an in situ hybridization study of GAD67 mRNA.
Topics: Aged; Aged, 80 and over; Animals; Corpus Striatum; Denervation; gamma-Aminobutyric Acid; Glutamate D | 1995 |
Consequences of nigrostriatal denervation on the gamma-aminobutyric acidic neurons of substantia nigra pars reticulata and superior colliculus in parkinsonian syndromes.
Topics: Animals; Corpus Striatum; Denervation; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hum | 1996 |
Noradrenoceptor antagonism with idazoxan improves L-dopa-induced dyskinesias in MPTP monkeys.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antiparkinson Agents | 2000 |
Parkinson's disease. Fresh factors to consider.
Topics: Animals; DNA; Dopamine; gamma-Aminobutyric Acid; MPTP Poisoning; Nerve Growth Factors; Nerve Tissue | 1991 |