gamma-aminobutyric acid has been researched along with Liver Failure in 7 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Liver Failure: Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hepatic encephalopathy is considered to be a reversible metabolic encephalopathy, which occurs as a complication of hepatocellular failure and is associated with increased portal-systemic shunting of gut-derived nitrogenous compounds." | 2.41 | Pathogenesis of hepatic encephalopathy. ( Jones, EA, 2000) |
| "Patients with hepatic encephalopathy show altered motor function, psychomotor slowing and hypokinesia." | 1.33 | Hypolocomotion in rats with chronic liver failure is due to increased glutamate and activation of metabotropic glutamate receptors in substantia nigra. ( Cauli, O; Erceg, S; Felipo, V; Llansola, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schousboe, A | 1 |
| Waagepetersen, HS | 1 |
| Leke, R | 1 |
| Bak, LK | 1 |
| Cauli, O | 2 |
| Llansola, M | 2 |
| Erceg, S | 1 |
| Felipo, V | 2 |
| Mlili, N | 1 |
| Jones, EA | 4 |
| Basile, AS | 2 |
| Bergasa, NV | 1 |
| Rothman, RB | 1 |
| Mukerjee, E | 1 |
| Vergalla, J | 1 |
4 reviews available for gamma-aminobutyric acid and Liver Failure
| Article | Year |
|---|---|
Effects of hyperammonemia on brain energy metabolism: controversial findings in vivo and in vitro.
Topics: Animals; Astrocytes; Brain; Cells, Cultured; Energy Metabolism; GABAergic Neurons; gamma-Aminobutyri | 2014 |
The involvement of ammonia with the mechanisms that enhance GABA-ergic neurotransmission in hepatic failure.
Topics: Ammonia; Animals; gamma-Aminobutyric Acid; Hepatic Encephalopathy; Humans; Liver Failure; Synaptic T | 1997 |
Does ammonia contribute to increased GABA-ergic neurotransmission in liver failure?
Topics: Ammonia; Animals; Behavior, Animal; Electrophysiology; gamma-Aminobutyric Acid; Humans; Liver Failur | 1998 |
Pathogenesis of hepatic encephalopathy.
Topics: Ammonia; gamma-Aminobutyric Acid; Glutamic Acid; Hepatic Encephalopathy; Humans; Liver Failure; Rece | 2000 |
3 other studies available for gamma-aminobutyric acid and Liver Failure
| Article | Year |
|---|---|
Hypolocomotion in rats with chronic liver failure is due to increased glutamate and activation of metabotropic glutamate receptors in substantia nigra.
Topics: Animals; Basal Ganglia; Chromones; Chronic Disease; GABA Antagonists; gamma-Aminobutyric Acid; Gluta | 2006 |
Motor activity is modulated via different neuronal circuits in rats with chronic liver failure than in normal rats.
Topics: Animals; Behavior, Animal; Brain; Chronic Disease; Dopamine; Excitatory Amino Acid Agonists; Excitat | 2007 |
Up-regulation of central mu-opioid receptors in a model of hepatic encephalopathy: a potential mechanism for increased sensitivity to morphine in liver failure.
Topics: Animals; Brain; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; gamma-Aminobutyric Acid; Hepatic | 2002 |