gamma-aminobutyric acid has been researched along with Lewy Body Disease in 5 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Lewy Body Disease: A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujishiro, H | 1 |
| Khundakar, AA | 1 |
| Hanson, PS | 1 |
| Erskine, D | 1 |
| Lax, NZ | 1 |
| Roscamp, J | 1 |
| Karyka, E | 1 |
| Tsefou, E | 1 |
| Singh, P | 1 |
| Cockell, SJ | 1 |
| Gribben, A | 1 |
| Ramsay, L | 1 |
| Blain, PG | 1 |
| Mosimann, UP | 1 |
| Lett, DJ | 1 |
| Elstner, M | 1 |
| Turnbull, DM | 1 |
| Xiang, CC | 1 |
| Brownstein, MJ | 1 |
| O'Brien, JT | 1 |
| Taylor, JP | 1 |
| Attems, J | 1 |
| Thomas, AJ | 1 |
| McKeith, IG | 1 |
| Morris, CM | 1 |
| Freund, HJ | 1 |
| Kuhn, J | 1 |
| Lenartz, D | 1 |
| Mai, JK | 1 |
| Schnell, T | 1 |
| Klosterkoetter, J | 1 |
| Sturm, V | 1 |
| Molina, JA | 1 |
| Gómez, P | 1 |
| Vargas, C | 1 |
| Ortiz, S | 1 |
| Pérez-Rial, S | 1 |
| Urigüen, L | 1 |
| Oliva, JM | 1 |
| Villanueva, C | 1 |
| Manzanares, J | 1 |
| Picklo, MJ | 1 |
| Olson, SJ | 1 |
| Hayes, JD | 1 |
| Markesbery, WR | 1 |
| Montine, TJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multi-targets, Single-lead GPi+NBM DBS in Parkinson's Disease With Mild Cognitive Impairment[NCT04571112] | 6 participants (Actual) | Interventional | 2017-12-04 | Completed | |||
| Simultaneous Deep Brain Stimulation of the Globus Pallidus Internus and the Nucleus Basalis of Meynert in Patients With Parkinson's Disease and Mild Cognitive Impairment[NCT05320523] | 10 participants (Anticipated) | Interventional | 2021-07-20 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for gamma-aminobutyric acid and Lewy Body Disease
| Article | Year |
|---|---|
Cognitive functions in a patient with Parkinson-dementia syndrome undergoing deep brain stimulation.
Topics: Acetylcholine; Aged; Arousal; Attention; Basal Nucleus of Meynert; Cholinergic Fibers; Cognition; Co | 2009 |
Cognitive functions in a patient with Parkinson-dementia syndrome undergoing deep brain stimulation.
Topics: Acetylcholine; Aged; Arousal; Attention; Basal Nucleus of Meynert; Cholinergic Fibers; Cognition; Co | 2009 |
Cognitive functions in a patient with Parkinson-dementia syndrome undergoing deep brain stimulation.
Topics: Acetylcholine; Aged; Arousal; Attention; Basal Nucleus of Meynert; Cholinergic Fibers; Cognition; Co | 2009 |
Cognitive functions in a patient with Parkinson-dementia syndrome undergoing deep brain stimulation.
Topics: Acetylcholine; Aged; Arousal; Attention; Basal Nucleus of Meynert; Cholinergic Fibers; Cognition; Co | 2009 |
4 other studies available for gamma-aminobutyric acid and Lewy Body Disease
| Article | Year |
|---|---|
Effects of gabapentin enacarbil on restless legs syndrome and leg pain in dementia with Lewy bodies.
Topics: Aged; Carbamates; Dopamine Agonists; Female; gamma-Aminobutyric Acid; Hallucinations; Humans; Japan; | 2014 |
Analysis of primary visual cortex in dementia with Lewy bodies indicates GABAergic involvement associated with recurrent complex visual hallucinations.
Topics: alpha-Synuclein; Alzheimer Disease; Amyloid beta-Peptides; Enzyme-Linked Immunosorbent Assay; gamma- | 2016 |
Neurotransmitter amino acid in cerebrospinal fluid of patients with dementia with Lewy bodies.
Topics: Age Factors; Age of Onset; Aged; Asparagine; Aspartic Acid; Body Mass Index; Brain; Cerebrospinal Fl | 2005 |
Elevation of AKR7A2 (succinic semialdehyde reductase) in neurodegenerative disease.
Topics: Aged; Alzheimer Disease; Animals; Astrocytes; Brain; Cell Compartmentation; Cerebral Cortex; gamma-A | 2001 |