gamma-aminobutyric acid has been researched along with Learning Disabilities in 30 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Learning Disabilities: Conditions characterized by a significant discrepancy between an individual's perceived level of intellect and their ability to acquire new language and other cognitive skills. These may result from organic or psychological conditions. Relatively common subtypes include DYSLEXIA, DYSCALCULIA, and DYSGRAPHIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Epilepsy is a common condition in people with learning disabilities with many patients continuing to suffer from seizures despite antiepileptic drug (AED) treatment." | 5.30 | A naturalistic study of the use of vigabatrin, lamotrigine and gabapentin in adults with learning disabilities. ( Bhaumik, S; Branford, D; Duggirala, C; Ismail, IA, 1997) |
| "Lamotrigine caused increased seizures in 24% of patients, especially when prescribed at a higher dose." | 5.30 | A naturalistic study of the use of vigabatrin, lamotrigine and gabapentin in adults with learning disabilities. ( Bhaumik, S; Branford, D; Duggirala, C; Ismail, IA, 1997) |
| "Pretreatment of sarcosine (600 mg/kg, i." | 1.43 | Effect of Sarcosine (a Glycine Transport 1 Inhibitor) and Risperidone (an Atypical antipsychotic Drug) on MK-801 Induced Learning and Memory Deficits in Rats. ( Ahmad, MA; Akhtar, M; Kumar, V; Najmi, AK, 2016) |
| "After infection with RML murine scrapie agent, transgenic (tg) mice expressing prion protein (PrP) without its glycophosphatidylinositol (GPI) membrane anchor (GPI(-/-) PrP tg mice) continue to make abundant amounts of the abnormally folded disease-associated PrPres but have a normal life span." | 1.35 | Scrapie-induced defects in learning and memory of transgenic mice expressing anchorless prion protein are associated with alterations in the gamma aminobutyric acid-ergic pathway. ( Bernard-Trifilo, J; Kunz, S; McGavern, D; Oldstone, MB; Sanchez-Alavez, M; Solforosi, L; Trifilo, MJ, 2008) |
| "Chronic transauricular kindled seizure was induced by repeated application of initially subconvulsive electrical stimulation (40 mA, 0." | 1.34 | [Effects of acute maximal electroshock and chronic transauricular kindled seizures on learning abilities in Sprague-Dawley rats]. ( Chen, Z; Li, Q; Wu, DC; Zhang, Q, 2007) |
| "Chronic transauricular kindled seizures induced CA1 neuron damage and a decrease in histamine levels in the hippocampus." | 1.34 | [Effects of acute maximal electroshock and chronic transauricular kindled seizures on learning abilities in Sprague-Dawley rats]. ( Chen, Z; Li, Q; Wu, DC; Zhang, Q, 2007) |
| "Different types of kindling seizure produce different effects on cognitive behavior: (1) an acute MES impairs learning ability, which may be associated with an abnormal plasticity and an increase of GABA in the hippocampus; (2) the chronic transauricular kindled seizure impairs retrieval memory mainly, which may be related to CA1 neuron damage and a decrease in histaminergic activity in the hippocampus." | 1.34 | [Effects of acute maximal electroshock and chronic transauricular kindled seizures on learning abilities in Sprague-Dawley rats]. ( Chen, Z; Li, Q; Wu, DC; Zhang, Q, 2007) |
| "Twenty children had spastic diplegia and three had quadriplegia." | 1.33 | Metabolite profile in the basal ganglia of children with cerebral palsy: a proton magnetic resonance spectroscopy study. ( Kubas, B; Kulak, W; Smigielska-Kuzia, J; Sobaniec, W; Walecki, J, 2006) |
| "Allopregnanolone is a progesterone metabolite and GABA-A receptor modulator with benzodiazepine like effects, including decreased learning and memory." | 1.32 | 3beta-20beta-dihydroxy-5alpha-pregnane (UC1011) antagonism of the GABA potentiation and the learning impairment induced in rats by allopregnanolone. ( Backstrom, T; Birzniece, V; Johansson, IM; Lundgren, P; Turkmen, S; Zingmark, E, 2004) |
| " The increased chloride ion uptake induced by increasing dosage of allopregnanolone in the presence of 10 micro m GABA was significantly decreased with UC1011 (P < 0." | 1.32 | 3beta-20beta-dihydroxy-5alpha-pregnane (UC1011) antagonism of the GABA potentiation and the learning impairment induced in rats by allopregnanolone. ( Backstrom, T; Birzniece, V; Johansson, IM; Lundgren, P; Turkmen, S; Zingmark, E, 2004) |
| "Epilepsy is a common condition in people with learning disabilities with many patients continuing to suffer from seizures despite antiepileptic drug (AED) treatment." | 1.30 | A naturalistic study of the use of vigabatrin, lamotrigine and gabapentin in adults with learning disabilities. ( Bhaumik, S; Branford, D; Duggirala, C; Ismail, IA, 1997) |
| "Lamotrigine caused increased seizures in 24% of patients, especially when prescribed at a higher dose." | 1.30 | A naturalistic study of the use of vigabatrin, lamotrigine and gabapentin in adults with learning disabilities. ( Bhaumik, S; Branford, D; Duggirala, C; Ismail, IA, 1997) |
| "In 1993, 27% of patients were being treated for epilepsy and in 1995/6, 30." | 1.30 | The management of epilepsy in a hospital for people with a learning disability. ( Carvill, S; Cassidy, G; Clarke, D, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.33) | 18.7374 |
| 1990's | 4 (13.33) | 18.2507 |
| 2000's | 11 (36.67) | 29.6817 |
| 2010's | 13 (43.33) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Gascoigne, DA | 1 |
| Serdyukova, NA | 1 |
| Aksenov, DP | 1 |
| Llorente-Ovejero, A | 1 |
| Manuel, I | 1 |
| Giralt, MT | 1 |
| RodrÃguez-Puertas, R | 1 |
| Hu, Y | 2 |
| Liu, M | 2 |
| Liu, P | 2 |
| Yan, JJ | 2 |
| Liu, MY | 1 |
| Zhang, GQ | 2 |
| Zhou, XJ | 1 |
| Yu, BY | 2 |
| Huang, S | 1 |
| Dai, Y | 1 |
| Zhang, Z | 1 |
| Hao, W | 1 |
| Chen, H | 1 |
| Kumar, V | 1 |
| Ahmad, MA | 1 |
| Najmi, AK | 1 |
| Akhtar, M | 1 |
| Sawano, E | 1 |
| Iwatani, K | 1 |
| Tominaga-Yoshino, K | 1 |
| Ogura, A | 1 |
| Tashiro, T | 1 |
| Tong, LM | 1 |
| Yoon, SY | 1 |
| Andrews-Zwilling, Y | 1 |
| Yang, A | 1 |
| Lin, V | 1 |
| Lei, H | 1 |
| Huang, Y | 1 |
| Lee, V | 1 |
| MacKenzie, G | 1 |
| Hooper, A | 1 |
| Maguire, J | 1 |
| Dadsetan, S | 1 |
| Balzano, T | 1 |
| Forteza, J | 1 |
| Agusti, A | 1 |
| Cabrera-Pastor, A | 1 |
| Taoro-Gonzalez, L | 1 |
| Hernandez-Rabaza, V | 1 |
| Gomez-Gimenez, B | 1 |
| ElMlili, N | 1 |
| Llansola, M | 1 |
| Felipo, V | 1 |
| Satomoto, M | 1 |
| Sun, Z | 1 |
| Adachi, YU | 1 |
| Makita, K | 1 |
| Trifilo, MJ | 1 |
| Sanchez-Alavez, M | 1 |
| Solforosi, L | 1 |
| Bernard-Trifilo, J | 1 |
| Kunz, S | 1 |
| McGavern, D | 1 |
| Oldstone, MB | 1 |
| Cui, Y | 1 |
| Costa, RM | 2 |
| Murphy, GG | 2 |
| Elgersma, Y | 1 |
| Zhu, Y | 1 |
| Gutmann, DH | 1 |
| Parada, LF | 1 |
| Mody, I | 1 |
| Silva, AJ | 2 |
| Staley, KJ | 1 |
| Anderson, AE | 1 |
| Fogel, SM | 1 |
| Smith, CT | 1 |
| Beninger, RJ | 1 |
| De Bartolo, P | 1 |
| Cutuli, D | 1 |
| Ricceri, L | 1 |
| Gelfo, F | 1 |
| Foti, F | 1 |
| Laricchiuta, D | 1 |
| Scattoni, ML | 1 |
| Calamandrei, G | 1 |
| Petrosini, L | 1 |
| Bissonette, GB | 1 |
| Bae, MH | 1 |
| Suresh, T | 1 |
| Jaffe, DE | 1 |
| Powell, EM | 1 |
| Huber, B | 1 |
| Tomka-Hoffmeister, M | 1 |
| Turkmen, S | 1 |
| Lundgren, P | 1 |
| Birzniece, V | 2 |
| Zingmark, E | 1 |
| Backstrom, T | 2 |
| Johansson, IM | 2 |
| Kulak, W | 1 |
| Sobaniec, W | 1 |
| Smigielska-Kuzia, J | 1 |
| Kubas, B | 1 |
| Walecki, J | 1 |
| Li, Q | 1 |
| Wu, DC | 1 |
| Zhang, Q | 1 |
| Chen, Z | 1 |
| Waddell, J | 1 |
| Bangasser, DA | 1 |
| Shors, TJ | 1 |
| Bickford, P | 1 |
| Hauck, A | 1 |
| Bhaumik, S | 2 |
| Branford, D | 1 |
| Duggirala, C | 1 |
| Ismail, IA | 1 |
| Carvill, S | 1 |
| Clarke, D | 1 |
| Cassidy, G | 1 |
| Heim, C | 1 |
| Zhang, J | 1 |
| Lan, J | 1 |
| Sieklucka, M | 1 |
| Kurz, T | 1 |
| Riederer, P | 1 |
| Gerlach, M | 1 |
| Sontag, KH | 1 |
| Federov, NB | 1 |
| Kogan, JH | 1 |
| Stern, J | 1 |
| Ohno, M | 1 |
| Kucherlapati, R | 1 |
| Jacks, T | 1 |
| Lindblad, C | 1 |
| Olsson, T | 1 |
| Youdim, MB | 1 |
| Ben-Shachar, D | 1 |
| Yehuda, S | 1 |
1 review available for gamma-aminobutyric acid and Learning Disabilities
| Article | Year |
|---|---|
Early Development of the GABAergic System and the Associated Risks of Neonatal Anesthesia.
Topics: Anesthesia, General; Animals; Animals, Newborn; Apoptosis; Brain; Child Behavior Disorders; Child, P | 2021 |
29 other studies available for gamma-aminobutyric acid and Learning Disabilities
| Article | Year |
|---|---|
Increase in cortical endocannabinoid signaling in a rat model of basal forebrain cholinergic dysfunction.
Topics: Animals; Antibodies, Monoclonal; Basal Forebrain; Cerebral Cortex; Cholinergic Neurons; Disease Mode | 2017 |
Effect of kai xin san on learning and memory in a rat model of paradoxical sleep deprivation.
Topics: Animals; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Cognition Disorders; Cyclic AMP | 2013 |
Docosahexaenoic acid intake ameliorates ketamine-induced impairment of spatial cognition and learning ability in ICR mice.
Topics: Animals; Cognition; Cognition Disorders; Docosahexaenoic Acids; gamma-Aminobutyric Acid; Hippocampus | 2014 |
Effect of Sarcosine (a Glycine Transport 1 Inhibitor) and Risperidone (an Atypical antipsychotic Drug) on MK-801 Induced Learning and Memory Deficits in Rats.
Topics: Animals; Antipsychotic Agents; Dizocilpine Maleate; gamma-Aminobutyric Acid; Glycine; Glycine Plasma | 2016 |
Reduction in NPY-positive neurons and dysregulation of excitability in young senescence-accelerated mouse prone 8 (SAMP8) hippocampus precede the onset of cognitive impairment.
Topics: Aging; Animals; Behavior, Animal; Cognition Disorders; Cyclic AMP Response Element-Binding Protein; | 2015 |
Enhancing GABA Signaling during Middle Adulthood Prevents Age-Dependent GABAergic Interneuron Decline and Learning and Memory Deficits in ApoE4 Mice.
Topics: Aging; Animals; Apolipoprotein E4; Female; GABA Agonists; gamma-Aminobutyric Acid; Gene Knock-In Tec | 2016 |
Reduced tonic inhibition in the dentate gyrus contributes to chronic stress-induced impairments in learning and memory.
Topics: Animals; Chronic Disease; Dentate Gyrus; Female; gamma-Aminobutyric Acid; Learning; Learning Disabil | 2016 |
Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy.
Topics: Animals; Anti-Inflammatory Agents; Cerebellum; Cyclic GMP; Cytokines; Dinoprostone; Disease Models, | 2016 |
Neonatal Sevoflurane Exposure Induces Adulthood Fear-induced Learning Disability and Decreases Glutamatergic Neurons in the Basolateral Amygdala.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Basolateral Nuclear Complex; Blood Gas Analysis; | 2018 |
Scrapie-induced defects in learning and memory of transgenic mice expressing anchorless prion protein are associated with alterations in the gamma aminobutyric acid-ergic pathway.
Topics: Animals; Behavior, Animal; Brain; Electrophysiology; gamma-Aminobutyric Acid; Glycosylphosphatidylin | 2008 |
Neurofibromin regulation of ERK signaling modulates GABA release and learning.
Topics: Animals; Extracellular Signal-Regulated MAP Kinases; Female; gamma-Aminobutyric Acid; Genes, Neurofi | 2008 |
Hyperactive interneurons impair learning in a neurofibromatosis model.
Topics: Animals; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; gamma-Aminobutyric Acid | 2009 |
Increased GABAergic activity in the region of the pedunculopontine and deep mesencephalic reticular nuclei reduces REM sleep and impairs learning in rats.
Topics: Animals; Avoidance Learning; Behavior, Animal; Electroencephalography; gamma-Aminobutyric Acid; Lear | 2010 |
Does age matter? Behavioral and neuro-anatomical effects of neonatal and adult basal forebrain cholinergic lesions.
Topics: Acetylcholine; Age Factors; Aging; Analysis of Variance; Animals; Animals, Newborn; Antibodies, Mono | 2010 |
Astrocyte-mediated hepatocyte growth factor/scatter factor supplementation restores GABAergic interneurons and corrects reversal learning deficits in mice.
Topics: Animals; Astrocytes; Biomarkers; Corpus Striatum; gamma-Aminobutyric Acid; Hepatocyte Growth Factor; | 2010 |
[Effect and mechanism of dingzhixiao wan on scopolamine-induced learning-memory impairment in mice].
Topics: Animals; Brain Chemistry; Dopamine; Drugs, Chinese Herbal; gamma-Aminobutyric Acid; Glutamic Acid; L | 2012 |
Limited efficacy of gabapentin in severe therapy-resistant epilepsies of learning-disabled patients.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 2003 |
3beta-20beta-dihydroxy-5alpha-pregnane (UC1011) antagonism of the GABA potentiation and the learning impairment induced in rats by allopregnanolone.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cerebral Cortex; Chlorides; Chromatography, High Pr | 2004 |
Metabolite profile in the basal ganglia of children with cerebral palsy: a proton magnetic resonance spectroscopy study.
Topics: Adolescent; Apgar Score; Aspartic Acid; Basal Ganglia; Cerebral Palsy; Child; Child, Preschool; Chol | 2006 |
[Effects of acute maximal electroshock and chronic transauricular kindled seizures on learning abilities in Sprague-Dawley rats].
Topics: Animals; Chronic Disease; Electric Stimulation; Electrodes; Electroshock; gamma-Aminobutyric Acid; H | 2007 |
The basolateral nucleus of the amygdala is necessary to induce the opposing effects of stressful experience on learning in males and females.
Topics: Amygdala; Animals; Conditioning, Eyelid; Female; GABA Agonists; gamma-Aminobutyric Acid; Learning; L | 2008 |
Motor learning deficits in aged rats are correlated with loss of cerebellar noradrenergic function.
Topics: Aging; Animals; Cerebellum; Drug Synergism; Electrophysiology; gamma-Aminobutyric Acid; Isoprotereno | 1993 |
Hypomania induced by gabapentin.
Topics: Acetates; Affect; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Electroenc | 1995 |
A naturalistic study of the use of vigabatrin, lamotrigine and gabapentin in adults with learning disabilities.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Comorbidity; Cyclohexanecarboxylic Acids; Dose-Respo | 1997 |
The management of epilepsy in a hospital for people with a learning disability.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Uti | 1999 |
Cerebral oligaemia episode triggers free radical formation and late cognitive deficiencies.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Carotid Stenosis; Cognition Disorders; Corpu | 2000 |
Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1.
Topics: Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Genes, ras; Hippocampus; In Vitro Techniqu | 2002 |
Allopregnanolone inhibits learning in the Morris water maze.
Topics: Anesthetics; Animals; Brain; Corticosterone; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hipp | 2002 |
Putative biological mechanisms of the effect of iron deficiency on brain biochemistry and behavior.
Topics: Animals; Behavior, Animal; Blood-Brain Barrier; Brain; Disease Models, Animal; Dopamine; gamma-Amino | 1989 |