Page last updated: 2024-10-15

gamma-aminobutyric acid and Ischemic Stroke

gamma-aminobutyric acid has been researched along with Ischemic Stroke in 8 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Ischemic Stroke: Stroke due to BRAIN ISCHEMIA resulting in interruption or reduction of blood flow to a part of the brain. When obstruction is due to a BLOOD CLOT formed within in a cerebral blood vessel it is a thrombotic stroke. When obstruction is formed elsewhere and moved to block a cerebral blood vessel (see CEREBRAL EMBOLISM) it is referred to as embolic stroke. Wake-up stroke refers to ischemic stroke occurring during sleep while cryptogenic stroke refers to ischemic stroke of unknown origin.

Research Excerpts

ExcerptRelevanceReference
"We measured 4 plasma amino acid neurotransmitters (glutamic acid, aspartic acid, gamma-aminobutyric acid, and glycine) among 3486 patients with ischemic stroke from 26 hospitals across China."5.69Plasma Amino Acid Neurotransmitters and Ischemic Stroke Prognosis: A Multicenter Prospective Study. ( Chen, J; Guo, D; He, J; Jia, Y; Peng, H; Shi, M; Sun, L; Wang, A; Wang, Y; Xu, Q; Xu, T; Yang, P; Zhang, Y; Zhong, C; Zhu, Z, 2023)
"Increased glutamic acid, aspartic acid, and gamma-aminobutyric acid and decreased glycine in plasma are associated with adverse outcomes after ischemic stroke, suggesting that plasma amino acid neurotransmitters may be potential intervention targets for improving prognosis of ischemic stroke."5.69Plasma Amino Acid Neurotransmitters and Ischemic Stroke Prognosis: A Multicenter Prospective Study. ( Chen, J; Guo, D; He, J; Jia, Y; Peng, H; Shi, M; Sun, L; Wang, A; Wang, Y; Xu, Q; Xu, T; Yang, P; Zhang, Y; Zhong, C; Zhu, Z, 2023)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's8 (100.00)2.80

Authors

AuthorsStudies
Chen, QM1
Yao, FR1
Sun, HW1
Chen, ZG1
Ke, J1
Liao, J1
Cai, XY1
Yu, LQ1
Wu, ZY1
Wang, Z1
Pan, X1
Liu, HY1
Li, L1
Zhang, QQ1
Ling, WH1
Fang, Q1
Mu, JD2
Ma, LX2
Zhang, Z2
Yu, WY2
Sun, TY2
Qian, X2
Tian, Y2
Wang, JX2
Zhang, YD1
Liu, BH1
Pu, J1
Li, ZQ1
Zhang, XR1
Liu, W2
He, X2
Lin, H2
Yang, M2
Dai, Y2
Chen, L4
Li, C2
Liang, S2
Tao, J2
Zhu, Z1
Yang, P1
Jia, Y1
Wang, Y1
Shi, M1
Zhong, C1
Peng, H1
Sun, L1
Guo, D1
Xu, Q1
Chen, J1
Wang, A1
Xu, T1
He, J1
Zhang, Y1
Cirillo, J1
Mooney, RA1
Ackerley, SJ1
Barber, PA1
Borges, VM1
Clarkson, AN1
Mangold, C1
Ren, A1
Smith, MC1
Stinear, CM1
Byblow, WD1
Khirug, S1
Soni, S1
Saez Garcia, M1
Tessier, M1
Zhou, L1
Kulesskaya, N1
Rauvala, H1
Lindholm, D1
Ludwig, A1
Molinari, F1
Rivera, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Anodal Transcranial Direct Current Stimulation on Cognition in Subacute Stroke[NCT05814588]56 participants (Actual)Interventional2023-04-02Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for gamma-aminobutyric acid and Ischemic Stroke

ArticleYear
Combining inhibitory and facilitatory repetitive transcranial magnetic stimulation (rTMS) treatment improves motor function by modulating GABA in acute ischemic stroke patients.
    Restorative neurology and neuroscience, 2021, Volume: 39, Issue:6

    Topics: gamma-Aminobutyric Acid; Humans; Ischemic Stroke; Recovery of Function; Stroke; Stroke Rehabilitatio

2021
Plasma Amino Acid Neurotransmitters and Ischemic Stroke Prognosis: A Multicenter Prospective Study.
    The American journal of clinical nutrition, 2023, Volume: 118, Issue:4

    Topics: Aspartic Acid; Biomarkers; Brain Ischemia; Cohort Studies; gamma-Aminobutyric Acid; Glutamic Acid; G

2023

Other Studies

6 other studies available for gamma-aminobutyric acid and Ischemic Stroke

ArticleYear
Acupuncture alleviates spinal hyperreflexia and motor dysfunction in post-ischemic stroke rats with spastic hypertonia via KCC2-mediated spinal GABA
    Experimental neurology, 2022, Volume: 354

    Topics: Acupuncture Therapy; Animals; gamma-Aminobutyric Acid; Humans; Ischemic Stroke; Muscle Hypertonia; M

2022
Acupuncture improves the structure of spastic muscle and decreases spasticity by enhancing GABA, KCC2, and GABAAγ2 in the brainstem in rats after ischemic stroke.
    Neuroreport, 2022, 06-08, Volume: 33, Issue:9

    Topics: Acupuncture Therapy; Animals; Brain Stem; gamma-Aminobutyric Acid; Infarction, Middle Cerebral Arter

2022
The effects of hypothermia on glutamate and γ-aminobutyric acid metabolism during ischemia in monkeys: a repeated-measures ANOVA study.
    Scientific reports, 2022, 08-25, Volume: 12, Issue:1

    Topics: Amino Acids; Analysis of Variance; Animals; Brain Ischemia; gamma-Aminobutyric Acid; Glutamic Acid;

2022
Ischemic stroke rehabilitation through optogenetic modulation of parvalbumin neurons in the contralateral motor cortex.
    Experimental neurology, 2023, Volume: 360

    Topics: Animals; gamma-Aminobutyric Acid; Humans; Infarction, Middle Cerebral Artery; Ischemic Stroke; Motor

2023
Ischemic stroke rehabilitation through optogenetic modulation of parvalbumin neurons in the contralateral motor cortex.
    Experimental neurology, 2023, Volume: 360

    Topics: Animals; gamma-Aminobutyric Acid; Humans; Infarction, Middle Cerebral Artery; Ischemic Stroke; Motor

2023
Ischemic stroke rehabilitation through optogenetic modulation of parvalbumin neurons in the contralateral motor cortex.
    Experimental neurology, 2023, Volume: 360

    Topics: Animals; gamma-Aminobutyric Acid; Humans; Infarction, Middle Cerebral Artery; Ischemic Stroke; Motor

2023
Ischemic stroke rehabilitation through optogenetic modulation of parvalbumin neurons in the contralateral motor cortex.
    Experimental neurology, 2023, Volume: 360

    Topics: Animals; gamma-Aminobutyric Acid; Humans; Infarction, Middle Cerebral Artery; Ischemic Stroke; Motor

2023
Neurochemical balance and inhibition at the subacute stage after stroke.
    Journal of neurophysiology, 2020, 05-01, Volume: 123, Issue:5

    Topics: Aged; Aged, 80 and over; Evoked Potentials, Motor; Female; gamma-Aminobutyric Acid; Humans; Ischemic

2020
Protective Role of Low Ethanol Administration Following Ischemic Stroke via Recovery of KCC2 and p75
    Molecular neurobiology, 2021, Volume: 58, Issue:3

    Topics: Animals; Apoptosis; Biological Transport; Biomarkers; Brain Infarction; Cell Survival; Chlorides; Di

2021