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gamma-aminobutyric acid and Intraocular Pressure

gamma-aminobutyric acid has been researched along with Intraocular Pressure in 14 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Intraocular Pressure: The pressure of the fluids in the eye.

Research Excerpts

ExcerptRelevanceReference
"We explored the melatonin influence on the level of amino acid neurotransmitters of the retina in glaucoma neuropathy in rats."7.79[Protective action of melatonin in experimental glaucoma in rats]. ( Mykheĭtseva, IM, 2013)
"Gabapentin is an antiepileptic drug widely approved as an add-on therapy for epilepsy treatment in human and dogs."6.84Effects of premedication with oral gabapentin on intraocular pressure changes following tracheal intubation in clinically normal dogs. ( Capik, I; Ghaffari, MS; Trbolova, A, 2017)
"Gabapentin has been used effectively to attenuate the pressor response to laryngoscopy and tracheal intubation."6.73Effect of oral gabapentin on the intraocular pressure and haemodynamic responses induced by tracheal intubation. ( Altun, GT; Ata, F; Baykara, M; Gülhan, N; Kaya, FN; Yavascaoglu, B, 2008)
"Glaucoma was caused by the prolong systemic introduction of adrenalin."5.39[Protective action of melatonin in experimental glaucoma in rats]. ( Mykheĭtseva, IM, 2013)
"Glaucoma is a leading cause of blindness."5.36Melatonin: a novel neuroprotectant for the treatment of glaucoma. ( Belforte, NA; Chianelli, MS; de Zavalía, N; Keller Sarmiento, MI; Moreno, MC; Rosenstein, RE; Sande, PH, 2010)
" This study aims to determine variations in the levels of L-glutamate and γ-aminobutyric acid (GABA), histaminergic, adrenergic, cholinergic, and serotonergic NTs in patients with primary glaucoma versus patients with cataract."4.02Elevated histamine levels in aqueous humor of patients with glaucoma. ( Angmo, D; Dada, T; Gowtham, L; Halder, N; Jayasundar, R; Singh, SB; Velpandian, T, 2021)
"We explored the melatonin influence on the level of amino acid neurotransmitters of the retina in glaucoma neuropathy in rats."3.79[Protective action of melatonin in experimental glaucoma in rats]. ( Mykheĭtseva, IM, 2013)
"Amacrine cells identified by GABA and glycine labeling were not significantly affected by experimental glaucoma, with a mean decrease of 15% compared with bilaterally untreated control cells (557 +/- 186 neurons/mm [glaucoma] versus 653."3.73The effect of experimental glaucoma and optic nerve transection on amacrine cells in the rat retina. ( Kielczewski, JL; Pease, ME; Quigley, HA, 2005)
"An inner retinal component removed by GABA and glycine was found in both the normal and glaucomatous eyes."3.72Functional damage to inner and outer retinal cells in experimental glaucoma. ( Lambrou, GN; Ofri, R; Percicot, CL; Perlman, I; Raz, D, 2003)
"25% betaxolol) in the rat retina following the ischemic injury induced by a transient increase of intraocular pressure (IOP)."3.71Betaxolol, a beta1-adrenoceptor antagonist, protects a transient ischemic injury of the retina. ( Hee Kim, Y; Jae Cho, G; Joon Kim, H; Kyung Song, J; Myong Yoo, J; Soo Kang, S; Sung Choi, W; Woo Cheon, E; Yun Cho, Y, 2002)
"Gabapentin is an antiepileptic drug widely approved as an add-on therapy for epilepsy treatment in human and dogs."2.84Effects of premedication with oral gabapentin on intraocular pressure changes following tracheal intubation in clinically normal dogs. ( Capik, I; Ghaffari, MS; Trbolova, A, 2017)
"Gabapentin has been used effectively to attenuate the pressor response to laryngoscopy and tracheal intubation."2.73Effect of oral gabapentin on the intraocular pressure and haemodynamic responses induced by tracheal intubation. ( Altun, GT; Ata, F; Baykara, M; Gülhan, N; Kaya, FN; Yavascaoglu, B, 2008)
"Glaucoma is a leading cause of irreversible blindness worldwide, and increased intraocular pressure (IOP) is a major risk factor."1.62Early Functional Impairment in Experimental Glaucoma Is Accompanied by Disruption of the GABAergic System and Inceptive Neuroinflammation. ( Elwood, BW; Godwin, CR; Gramlich, OW; Kuehn, MH; Wadkins, D, 2021)
"Glaucoma was caused by the prolong systemic introduction of adrenalin."1.39[Protective action of melatonin in experimental glaucoma in rats]. ( Mykheĭtseva, IM, 2013)
"Glaucoma is a leading cause of blindness."1.36Melatonin: a novel neuroprotectant for the treatment of glaucoma. ( Belforte, NA; Chianelli, MS; de Zavalía, N; Keller Sarmiento, MI; Moreno, MC; Rosenstein, RE; Sande, PH, 2010)
"Complete optic nerve transection was performed unilaterally in nine rats with survival for 1 (n = 4) and 3 (n = 5) months."1.33The effect of experimental glaucoma and optic nerve transection on amacrine cells in the rat retina. ( Kielczewski, JL; Pease, ME; Quigley, HA, 2005)
"Ischemia was induced in the rat retina by raising the IOP above the systolic blood pressure for 60min."1.31Betaxolol, a beta1-adrenoceptor antagonist, protects a transient ischemic injury of the retina. ( Hee Kim, Y; Jae Cho, G; Joon Kim, H; Kyung Song, J; Myong Yoo, J; Soo Kang, S; Sung Choi, W; Woo Cheon, E; Yun Cho, Y, 2002)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (21.43)18.2507
2000's4 (28.57)29.6817
2010's5 (35.71)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Gowtham, L1
Halder, N1
Angmo, D1
Singh, SB1
Jayasundar, R1
Dada, T1
Velpandian, T1
Gramlich, OW1
Godwin, CR1
Wadkins, D1
Elwood, BW1
Kuehn, MH1
Trbolova, A1
Ghaffari, MS1
Capik, I1
Kavitha, J1
Parida, S1
Kundra, P1
Srinivasan, R1
Mykheĭtseva, IM1
Bailey, JN1
Yaspan, BL1
Pasquale, LR1
Hauser, MA1
Kang, JH1
Loomis, SJ1
Brilliant, M1
Budenz, DL1
Christen, WG1
Fingert, J1
Gaasterland, D1
Gaasterland, T1
Kraft, P1
Lee, RK1
Lichter, PR1
Liu, Y1
McCarty, CA1
Moroi, SE1
Richards, JE1
Realini, T1
Schuman, JS1
Scott, WK1
Singh, K1
Sit, AJ1
Vollrath, D1
Wollstein, G1
Zack, DJ1
Zhang, K1
Pericak-Vance, MA1
Allingham, RR1
Weinreb, RN1
Haines, JL1
Wiggs, JL1
Kaya, FN1
Yavascaoglu, B1
Baykara, M1
Altun, GT1
Gülhan, N1
Ata, F1
Belforte, NA1
Moreno, MC1
de Zavalía, N1
Sande, PH1
Chianelli, MS1
Keller Sarmiento, MI1
Rosenstein, RE1
Woo Cheon, E1
Hee Kim, Y1
Yun Cho, Y1
Joon Kim, H1
Soo Kang, S1
Jae Cho, G1
Myong Yoo, J1
Kyung Song, J1
Sung Choi, W1
Raz, D1
Perlman, I1
Percicot, CL1
Lambrou, GN1
Ofri, R1
Kielczewski, JL1
Pease, ME1
Quigley, HA1
Osborne, NN1
Herrera, AJ1
Perlman, JI1
McCole, SM1
Pulluru, P1
Chang, CJ1
Lam, TT1
Tso, MO1
Mincione, G1
Menabuoni, L1
Briganti, F1
Mincione, F1
Scozzafava, A1
Supuran, CT1

Trials

3 trials available for gamma-aminobutyric acid and Intraocular Pressure

ArticleYear
Effects of premedication with oral gabapentin on intraocular pressure changes following tracheal intubation in clinically normal dogs.
    BMC veterinary research, 2017, Sep-19, Volume: 13, Issue:1

    Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dogs; Gabapentin; gamma-Aminobutyric Acid;

2017
Oral gabapentin premedication for elderly patients undergoing intraocular surgery.
    The British journal of ophthalmology, 2013, Volume: 97, Issue:7

    Topics: Administration, Oral; Amines; Analgesics; Anesthesia, Conduction; Anti-Anxiety Agents; Blood Pressur

2013
Effect of oral gabapentin on the intraocular pressure and haemodynamic responses induced by tracheal intubation.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:8

    Topics: Administration, Oral; Adult; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobut

2008

Other Studies

11 other studies available for gamma-aminobutyric acid and Intraocular Pressure

ArticleYear
Elevated histamine levels in aqueous humor of patients with glaucoma.
    Molecular vision, 2021, Volume: 27

    Topics: Adult; Aged; Aqueous Humor; Case-Control Studies; Cataract; Chromatography, Liquid; Female; gamma-Am

2021
Early Functional Impairment in Experimental Glaucoma Is Accompanied by Disruption of the GABAergic System and Inceptive Neuroinflammation.
    International journal of molecular sciences, 2021, Jul-15, Volume: 22, Issue:14

    Topics: Animals; Cytoskeletal Proteins; Disease Models, Animal; Eye Proteins; Female; GABAergic Neurons; gam

2021
[Protective action of melatonin in experimental glaucoma in rats].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2013, Volume: 59, Issue:1

    Topics: Animals; Antioxidants; Aspartic Acid; Chromatography, Ion Exchange; Epinephrine; gamma-Aminobutyric

2013
Hypothesis-independent pathway analysis implicates GABA and acetyl-CoA metabolism in primary open-angle glaucoma and normal-pressure glaucoma.
    Human genetics, 2014, Volume: 133, Issue:10

    Topics: Acetyl Coenzyme A; Case-Control Studies; Cluster Analysis; Female; gamma-Aminobutyric Acid; Genetic

2014
Melatonin: a novel neuroprotectant for the treatment of glaucoma.
    Journal of pineal research, 2010, Volume: 48, Issue:4

    Topics: Animals; Arginine; gamma-Aminobutyric Acid; Glaucoma; Glutamate Decarboxylase; Glutamic Acid; Histoc

2010
Betaxolol, a beta1-adrenoceptor antagonist, protects a transient ischemic injury of the retina.
    Experimental eye research, 2002, Volume: 75, Issue:5

    Topics: Animals; Antihypertensive Agents; Betaxolol; Choline O-Acetyltransferase; gamma-Aminobutyric Acid; I

2002
Functional damage to inner and outer retinal cells in experimental glaucoma.
    Investigative ophthalmology & visual science, 2003, Volume: 44, Issue:8

    Topics: Aminobutyrates; Animals; Electroretinography; gamma-Aminobutyric Acid; Glaucoma; Glycine; Interneuro

2003
The effect of experimental glaucoma and optic nerve transection on amacrine cells in the rat retina.
    Investigative ophthalmology & visual science, 2005, Volume: 46, Issue:9

    Topics: Amacrine Cells; Animals; Axons; Cell Count; Disease Models, Animal; gamma-Aminobutyric Acid; Glaucom

2005
The effect of experimental ischaemia and excitatory amino acid agonists on the GABA and serotonin immunoreactivities in the rabbit retina.
    Neuroscience, 1994, Volume: 59, Issue:4

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amin

1994
Disturbances in the distribution of neurotransmitters in the rat retina after ischemia.
    Current eye research, 1996, Volume: 15, Issue:6

    Topics: Animals; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Intraocular Pressure; Ischemi

1996
Carbonic anhydrase inhibitors. Part 79. Synthesis of topically acting sulfonamides incorporating GABA moieties in their molecule, with long-lasting intraocular pressure-lowering properties.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 1999, Volume: 9, Issue:2

    Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Cell Membrane; Cornea; Cytosol; Dis

1999