Page last updated: 2024-10-16

gamma-aminobutyric acid and Inflammatory Bowel Diseases

gamma-aminobutyric acid has been researched along with Inflammatory Bowel Diseases in 5 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Inflammatory Bowel Diseases: Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS.

Research Excerpts

ExcerptRelevanceReference
"Secondary outcomes were postoperative pain scores, opioid-related side effects, and patient's length of hospital stay."2.79Effect of a preoperative gabapentin on postoperative analgesia in patients with inflammatory bowel disease following major bowel surgery: a randomized, placebo-controlled trial. ( Fischer, H; Friedman, Z; Guerina, L; Siddiqui, NT, 2014)
"Currently, treatment of stress-related gastrointestinal disorders, such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), is mainly symptomatic since there is no drug on the market that solves effectively diverse disease symptoms and comorbid states."2.55GABAergic System in Action: Connection to Gastrointestinal Stress-related Disorders. ( Auteri, M; Jembrek, MJ; Serio, R; Vlainic, J, 2017)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Wang, J1
Liu, G1
Xu, K1
Ai, K1
Huang, W1
Zhang, J1
Siddiqui, NT1
Fischer, H1
Guerina, L1
Friedman, Z1
Auteri, M2
Zizzo, MG1
Serio, R2
Meleine, M1
Boudieu, L1
Gelot, A1
Muller, E1
Lashermes, A1
Matricon, J1
Silberberg, C1
Theodorou, V1
Eschalier, A1
Ardid, D1
Carvalho, FA1
Jembrek, MJ1
Vlainic, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Role of the Gut Microbiome as Determinant of Depression in Multiple Sclerosis Subjects[NCT05808101]120 participants (Anticipated)Observational2022-01-27Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for gamma-aminobutyric acid and Inflammatory Bowel Diseases

ArticleYear
GABA and GABA receptors in the gastrointestinal tract: from motility to inflammation.
    Pharmacological research, 2015, Volume: 93

    Topics: Animals; gamma-Aminobutyric Acid; Gastrointestinal Motility; Gastrointestinal Tract; Humans; Inflamm

2015
GABAergic System in Action: Connection to Gastrointestinal Stress-related Disorders.
    Current pharmaceutical design, 2017, Volume: 23, Issue:27

    Topics: Animals; Benzodiazepines; gamma-Aminobutyric Acid; Gastrointestinal Diseases; Humans; Inflammatory B

2017

Trials

1 trial available for gamma-aminobutyric acid and Inflammatory Bowel Diseases

ArticleYear
Effect of a preoperative gabapentin on postoperative analgesia in patients with inflammatory bowel disease following major bowel surgery: a randomized, placebo-controlled trial.
    Pain practice : the official journal of World Institute of Pain, 2014, Volume: 14, Issue:2

    Topics: Abdomen; Adult; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Double-Blind Me

2014

Other Studies

2 other studies available for gamma-aminobutyric acid and Inflammatory Bowel Diseases

ArticleYear
The role of neurotransmitters in mediating the relationship between brain alterations and depressive symptoms in patients with inflammatory bowel disease.
    Human brain mapping, 2023, Volume: 44, Issue:16

    Topics: Brain; Depression; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inflammatory Bowel Dis

2023
Comparative effects of α2δ-1 ligands in mouse models of colonic hypersensitivity.
    World journal of gastroenterology, 2016, Aug-21, Volume: 22, Issue:31

    Topics: Amines; Animals; Calcium Channels; Cyclohexanecarboxylic Acids; Dextran Sulfate; Disease Models, Ani

2016