gamma-aminobutyric acid has been researched along with Hypothermia in 20 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Hypothermia: Lower than normal body temperature, especially in warm-blooded animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The author describes six cases in which gabapentin treatment reduced the frequency of hot flashes." | 7.70 | Gabapentin's effects on hot flashes and hypothermia. ( Guttuso, TJ, 2000) |
| "Duodenal ulcers were also observed in about 80% of the hypothermic animals treated with the highest dose of baclofen." | 5.28 | [Ulcerogenic effect of a GABA derivative, baclofen, in the rat: effect of hypothermia]. ( Goto, Y; Hara, N; Hara, Y; Natsume, Y, 1990) |
| "The author describes six cases in which gabapentin treatment reduced the frequency of hot flashes." | 3.70 | Gabapentin's effects on hot flashes and hypothermia. ( Guttuso, TJ, 2000) |
| " Bicuculline increases GABA-induced hypothermia, does not modify DAVA (250 mg/kg) and VPA (100 and 400 mg/kg) hypothermia and antagonizes initial hypothermia by DAVA (1000 mg/kg) and VPA (200 mg/kg) and late hypothermia by DAVA (500 mg/kg) and VPA (200 mg/kg)." | 3.67 | Involvement of bicuculline-insensitive receptors in the hypothermic effect of GABA and its agonists. ( Durán, JA; Miñano, FJ; Sancibrián, M; Serrano, JS, 1985) |
| " Hypothermia in midwinter revealed a marked increase in GABA and glutamine due to active decarboxylation and amidation of glutamic acid." | 3.66 | Hibernation hypothermia and metabolism in hedgehogs--changes in free amino acids and related compounds. ( Al-Badry, KS; Taha, HM, 1982) |
| "When tiagabine was injected 10 min following onset of reperfusion, GABA levels remained elevated (200-470%) for 90 min." | 1.29 | Postischemic inhibition of GABA reuptake by tiagabine slows neuronal death in the gerbil hippocampus. ( Inglefield, JR; Perry, JM; Schwartz, RD, 1995) |
| " We used in vivo microdialysis to determine a suitable dosing regimen for tiagabine (NNC328) to elevate extracellular levels of GABA within the hippocampus." | 1.29 | Postischemic inhibition of GABA reuptake by tiagabine slows neuronal death in the gerbil hippocampus. ( Inglefield, JR; Perry, JM; Schwartz, RD, 1995) |
| " Fischer 344 rats were separated into multiple groups and underwent two dose-response evaluations." | 1.28 | Cerebral radioprotection by pentobarbital: dose-response characteristics and association with GABA agonist activity. ( Delaney, T; Friedman, R; Oldfield, EH; Olson, JJ; Orr, K, 1990) |
| "Duodenal ulcers were also observed in about 80% of the hypothermic animals treated with the highest dose of baclofen." | 1.28 | [Ulcerogenic effect of a GABA derivative, baclofen, in the rat: effect of hypothermia]. ( Goto, Y; Hara, N; Hara, Y; Natsume, Y, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (25.00) | 18.7374 |
| 1990's | 8 (40.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 2 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, BH | 1 |
| Pu, J | 1 |
| Li, ZQ | 1 |
| Zhang, XR | 1 |
| Tabarean, IV | 1 |
| Osaka, T | 2 |
| Izco, M | 1 |
| Gutierrez-Lopez, MD | 1 |
| Marchant, I | 1 |
| O'Shea, E | 1 |
| Colado, MI | 1 |
| Al-Badry, KS | 1 |
| Taha, HM | 1 |
| DeFeudis, FV | 1 |
| Inglefield, JR | 1 |
| Perry, JM | 1 |
| Schwartz, RD | 1 |
| Tomkins, DM | 1 |
| Sellers, EM | 1 |
| Fletcher, PJ | 1 |
| Li, PA | 1 |
| He, QP | 1 |
| Miyashita, H | 1 |
| Howllet, W | 1 |
| Siesjö, BK | 1 |
| Shuaib, A | 1 |
| Guttuso, TJ | 1 |
| Bruins Slot, LA | 1 |
| Tarayre, JP | 1 |
| Koek, W | 1 |
| Ribet, JP | 1 |
| Colpaert, FC | 1 |
| Costentin, J | 1 |
| Richardson, DL | 1 |
| Scudder, CL | 1 |
| Blier, P | 1 |
| Bouchard, C | 1 |
| Pogorelyĭ, VN | 1 |
| Gaeva, LM | 1 |
| Hara, N | 2 |
| Hara, Y | 2 |
| Natsume, Y | 2 |
| Goto, Y | 2 |
| Olson, JJ | 1 |
| Friedman, R | 1 |
| Orr, K | 1 |
| Delaney, T | 1 |
| Oldfield, EH | 1 |
| Serrano, JS | 1 |
| Miñano, FJ | 1 |
| Sancibrián, M | 1 |
| Durán, JA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Studying the Impact of Exercise on Hot Flashes Using Mobile Fitbit Flex, MENQOL Scale and Hot Flash Diary[NCT03236896] | 35 participants (Actual) | Interventional | 2015-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for gamma-aminobutyric acid and Hypothermia
| Article | Year |
|---|---|
Involvement of GABA and other inhibitory amino acids in thermoregulation.
Topics: Allylglycine; Amino Acids; Animals; Body Temperature Regulation; Brain; Fever; gamma-Aminobutyric Ac | 1984 |
[Modulation of dopaminergic receptor sensitivity in the central nervous system: important parameters in synaptic function regulation].
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Behavior; Corpus Stria | 1979 |
18 other studies available for gamma-aminobutyric acid and Hypothermia
| Article | Year |
|---|---|
The effects of hypothermia on glutamate and γ-aminobutyric acid metabolism during ischemia in monkeys: a repeated-measures ANOVA study.
Topics: Amino Acids; Analysis of Variance; Animals; Brain Ischemia; gamma-Aminobutyric Acid; Glutamic Acid; | 2022 |
Neurotensin induces hypothermia by activating both neuronal neurotensin receptor 1 and astrocytic neurotensin receptor 2 in the median preoptic nucleus.
Topics: Animals; Astrocytes; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Hypothermia; Male; | 2020 |
Hypoxia-induced hypothermia mediated by GABA in the rostral parapyramidal area of the medulla oblongata.
Topics: Analysis of Variance; Animals; Bicuculline; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hy | 2014 |
2-Deoxy-D-glucose-induced hypothermia in anesthetized rats: Lack of forebrain contribution and critical involvement of the rostral raphe/parapyramidal regions of the medulla oblongata.
Topics: Anesthetics, Intravenous; Animals; Chloralose; Decerebrate State; Deoxyglucose; GABA Agents; gamma-A | 2015 |
Administration of neurotoxic doses of MDMA reduces sensitivity to ethanol and increases GAT-1 immunoreactivity in mice striatum.
Topics: Alcohol Drinking; Animals; Corpus Striatum; Dopamine; Drug Tolerance; Ethanol; GABA Plasma Membrane | 2010 |
Hibernation hypothermia and metabolism in hedgehogs--changes in free amino acids and related compounds.
Topics: Amino Acids; Animals; gamma-Aminobutyric Acid; Glutamine; Hedgehogs; Hibernation; Hypothermia | 1982 |
Postischemic inhibition of GABA reuptake by tiagabine slows neuronal death in the gerbil hippocampus.
Topics: Animals; Cell Death; gamma-Aminobutyric Acid; Gerbillinae; Hippocampus; Hypothermia; Male; Microdial | 1995 |
Effect of dorsal raphe injections of the GABAA agonist, muscimol, on ethanol intake and measures of intoxication in Wistar rats.
Topics: Alcohol Drinking; Alcoholic Intoxication; Animals; Conditioning, Operant; Drinking Behavior; Ethanol | 1994 |
Hypothermia ameliorates ischemic brain damage and suppresses the release of extracellular amino acids in both normo- and hyperglycemic subjects.
Topics: Animals; Brain; Brain Ischemia; Corpus Striatum; Disease Models, Animal; Excitatory Amino Acids; Ext | 1999 |
Gabapentin's effects on hot flashes and hypothermia.
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gab | 2000 |
Experimental conditions for the continuous subcutaneous infusion of four central analgesics in rats.
Topics: Acetates; Amines; Analgesics; Anesthetics, Dissociative; Animals; Anticonvulsants; Antidepressive Ag | 2002 |
Microwave irradiation and brain gamma-aminobutyric acid levels in mice.
Topics: Aminobutyrates; Animals; Brain Chemistry; gamma-Aminobutyric Acid; Hypothermia; Male; Mice; Microwav | 1976 |
Effect of repeated electroconvulsive shocks on serotonergic neurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Brain Stem; Dendrites; Electroco | 1992 |
[Changes in the reactivity of the cerebral and peripheral vessels to biologically active substances under the influence of hyper- and hypothermia].
Topics: Animals; Biogenic Amines; Blood Pressure; Cats; Cerebral Arteries; Cerebral Veins; Fever; gamma-Amin | 1990 |
Gastric hyperacidity and mucosal damage caused by hypothermia correlate with increase in GABA concentrations of the rat brain.
Topics: Aminooxyacetic Acid; Anesthesia; Animals; Brain Chemistry; Cold Temperature; gamma-Aminobutyric Acid | 1991 |
Cerebral radioprotection by pentobarbital: dose-response characteristics and association with GABA agonist activity.
Topics: Anesthesia, General; Animals; Brain; Diazepam; Dose-Response Relationship, Drug; Dose-Response Relat | 1990 |
[Ulcerogenic effect of a GABA derivative, baclofen, in the rat: effect of hypothermia].
Topics: Animals; Baclofen; Duodenal Ulcer; gamma-Aminobutyric Acid; Gastric Acid; Gastric Mucosa; Hypothermi | 1990 |
Involvement of bicuculline-insensitive receptors in the hypothermic effect of GABA and its agonists.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Bicuculline; Body Temperature; Drug Interactions; Female | 1985 |