gamma-aminobutyric acid has been researched along with Hypotension in 27 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The current data demonstrate that GABAergic mechanisms in the RVLM are responsible for the hypotension and sympathoinhibition of moxonidine." | 7.77 | GABAergic mechanism in the rostral ventrolateral medulla contributes to the hypotension of moxonidine. ( Ni, X; Peng, JF; Su, DF; Sun, T; Wang, W; Wang, WZ; Wang, YK; Wu, ZT; Xu, MJ; Yuan, WJ, 2011) |
| "Acute hypotension was induced by intravenous infusion of sodium nitroprusside (SNP)." | 5.36 | [Changes of gamma-aminobutyric acid and glycine released in the medial vestibular nucleus following acute hypotension in conscious rats]. ( An, Y; Jin, QH; Jin, YZ; Li, XL, 2010) |
| "The current data demonstrate that GABAergic mechanisms in the RVLM are responsible for the hypotension and sympathoinhibition of moxonidine." | 3.77 | GABAergic mechanism in the rostral ventrolateral medulla contributes to the hypotension of moxonidine. ( Ni, X; Peng, JF; Su, DF; Sun, T; Wang, W; Wang, WZ; Wang, YK; Wu, ZT; Xu, MJ; Yuan, WJ, 2011) |
| "A 31-y-old epileptic man developed coma and shock after suicidally ingesting large amounts of valproic acid and gabapentin." | 3.69 | Hemodialysis and hemoperfusion for treatment of valproic acid and gabapentin poisoning. ( Brady, LA; Do, SM; Fernandez, MC; Kloster, JC; Prosnitz, EH; Ruffenach, SJ; Salmon, JV; Villarin, A; Walter, FG, 1996) |
| "Concentrations of gamma-aminobutyric acid (GABA) and other amino acids were measured in microdissected areas of the rostral ventro-lateral medulla (RVL), nucleus tractus solitarii (NTS) and caudal ventrolateral medulla (CVL) of the rat, and effects on the amino acid levels, of hypotension induced by hexamethonium and nifedipine were examined." | 3.68 | Hypotension decreases GABA levels in brainstem regions of the rat. ( Kihara, M; Kubo, T; Misu, Y, 1990) |
| "Gamma-aminobutyric acid (GABA) is a potent amino acid neurotransmitter with various physiologic effects throughout the body." | 2.38 | Gamma-aminobutyric acid and the liver. ( Minuk, GY, 1993) |
| "Acute hypotension was induced by intravenous infusion of sodium nitroprusside (SNP)." | 1.36 | [Changes of gamma-aminobutyric acid and glycine released in the medial vestibular nucleus following acute hypotension in conscious rats]. ( An, Y; Jin, QH; Jin, YZ; Li, XL, 2010) |
| "Acute hypotension was induced by infusing sodium nitroprusside (SNP) into the femoral vein." | 1.36 | Changes of some amino acid concentrations in the medial vestibular nucleus of conscious rats following acute hypotension. ( An, Y; Jin, QH; Jin, YZ; Kim, MS; Li, XL; Park, BR, 2010) |
| "Malignant cerebral infarction (MaCI) treated with mechanical ventilation, mannitol, or barbiturates has a mortality of about 80% and survivors show severe disability." | 1.33 | Prolonged moderate hypothermia in massive hemispheric infarction: clinical experience. ( Escuret, E; Heroum, C; Milhaud, D; Thouvenot, E, 2005) |
| "Quetiapine overdose is associated with coma, QTc prolongation and hypotension." | 1.31 | Massive gabapentin and presumptive quetiapine overdose. ( Cutino, L; Dunaway, MD; Spiller, HA, 2002) |
| "His hypotension was refractory to crystalloid and pressor infusions, but resolved during concurrent hemoperfusion and hemodialysis to enhance elimination of valproic acid." | 1.29 | Hemodialysis and hemoperfusion for treatment of valproic acid and gabapentin poisoning. ( Brady, LA; Do, SM; Fernandez, MC; Kloster, JC; Prosnitz, EH; Ruffenach, SJ; Salmon, JV; Villarin, A; Walter, FG, 1996) |
| "A 31-y-old epileptic man developed coma and shock after suicidally ingesting large amounts of valproic acid and gabapentin." | 1.29 | Hemodialysis and hemoperfusion for treatment of valproic acid and gabapentin poisoning. ( Brady, LA; Do, SM; Fernandez, MC; Kloster, JC; Prosnitz, EH; Ruffenach, SJ; Salmon, JV; Villarin, A; Walter, FG, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (29.63) | 18.7374 |
| 1990's | 5 (18.52) | 18.2507 |
| 2000's | 8 (29.63) | 29.6817 |
| 2010's | 5 (18.52) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, W | 2 |
| Yamaguchi, S | 1 |
| Koyama, M | 1 |
| Nakamura, K | 1 |
| Li, XL | 2 |
| An, Y | 2 |
| Jin, QH | 2 |
| Jin, YZ | 2 |
| Kim, MS | 1 |
| Park, BR | 1 |
| Li, P | 1 |
| Longhurst, JC | 1 |
| Chen, CY | 2 |
| Bonham, AC | 2 |
| Peng, JF | 1 |
| Wu, ZT | 1 |
| Wang, YK | 1 |
| Yuan, WJ | 1 |
| Sun, T | 1 |
| Ni, X | 1 |
| Su, DF | 1 |
| Xu, MJ | 1 |
| Wang, WZ | 1 |
| Spiller, HA | 1 |
| Dunaway, MD | 1 |
| Cutino, L | 1 |
| Pelaez, NM | 1 |
| Schreihofer, AM | 1 |
| Guyenet, PG | 1 |
| Kimura, M | 1 |
| Hayakawa, K | 1 |
| Sansawa, H | 1 |
| TAKAHASHI, H | 1 |
| KOSHINO, C | 1 |
| IKEDA, O | 1 |
| BHARGAVA, KP | 1 |
| BHATTACHARYA, SS | 1 |
| SRIMAL, RC | 1 |
| SAMUELSSON, G | 1 |
| Penumalee, S | 1 |
| Kissner, PZ | 1 |
| Migdal, SD | 1 |
| Hobgood, C | 1 |
| Hevia, A | 1 |
| Hinchey, P | 1 |
| Milhaud, D | 1 |
| Thouvenot, E | 1 |
| Heroum, C | 1 |
| Escuret, E | 1 |
| Williford, DJ | 1 |
| Hamilton, BL | 1 |
| Souza, JD | 1 |
| Williams, TP | 1 |
| DiMicco, JA | 1 |
| Gillis, RA | 1 |
| Takemoto, Y | 1 |
| Minuk, GY | 1 |
| Fernandez, MC | 1 |
| Walter, FG | 1 |
| Kloster, JC | 1 |
| Do, SM | 1 |
| Brady, LA | 1 |
| Villarin, A | 1 |
| Ruffenach, SJ | 1 |
| Prosnitz, EH | 1 |
| Salmon, JV | 1 |
| Honjo, K | 1 |
| Goshima, Y | 1 |
| Miyamae, T | 1 |
| Misu, Y | 2 |
| Kishi, T | 1 |
| Hirooka, Y | 1 |
| Sakai, K | 1 |
| Shigematsu, H | 1 |
| Shimokawa, H | 1 |
| Takeshita, A | 1 |
| Kajekar, R | 1 |
| Mutoh, T | 1 |
| Zhang, SS | 1 |
| Wang, LF | 1 |
| Fu, SX | 1 |
| Kubo, T | 1 |
| Kihara, M | 1 |
| Phillis, JW | 1 |
| Walter, GA | 1 |
| Magnusson, A | 1 |
| Höglund, U | 1 |
| Sjöquist, M | 1 |
| Sasaki, S | 1 |
| Lee, LC | 1 |
| Nakamura, Y | 1 |
| Iyota, I | 1 |
| Fukuyama, M | 1 |
| Inoue, A | 1 |
| Takeda, K | 1 |
| Yoshimura, M | 1 |
| Nakagawa, M | 1 |
| Ijichi, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Øresund Copenhagen-Malmø Acute Stroke Cooling Trial[NCT01500421] | Phase 2 | 31 participants (Actual) | Interventional | 2008-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for gamma-aminobutyric acid and Hypotension
| Article | Year |
|---|---|
Postexercise hypotension: central mechanisms.
Topics: Animals; Baroreflex; Blood Pressure; Brain Stem; Exercise; gamma-Aminobutyric Acid; Humans; Hyperten | 2010 |
Gamma-aminobutyric acid and the liver.
Topics: Animals; Bacterial Infections; Biological Transport, Active; gamma-Aminobutyric Acid; Hepatic Enceph | 1993 |
25 other studies available for gamma-aminobutyric acid and Hypotension
| Article | Year |
|---|---|
Evaluation of the Antihypertensive Activity of Eggplant Acetylcholine and γ-Aminobutyric Acid in Spontaneously Hypertensive Rats.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Blood Pressure; gamma-Aminobutyric Acid; Hypotensio | 2023 |
[Changes of gamma-aminobutyric acid and glycine released in the medial vestibular nucleus following acute hypotension in conscious rats].
Topics: Acute Disease; Animals; Chromatography, High Pressure Liquid; Ear, Inner; gamma-Aminobutyric Acid; G | 2010 |
Changes of some amino acid concentrations in the medial vestibular nucleus of conscious rats following acute hypotension.
Topics: Acute Disease; Animals; Blood Pressure; Chromatography, High Pressure Liquid; gamma-Aminobutyric Aci | 2010 |
Neural mechanism of electroacupuncture's hypotensive effects.
Topics: Analgesics, Opioid; Animals; Brain Stem; Electroacupuncture; gamma-Aminobutyric Acid; Humans; Hypote | 2010 |
GABAergic mechanism in the rostral ventrolateral medulla contributes to the hypotension of moxonidine.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Blotting, Western; GABA-A Receptor Antagonists; GA | 2011 |
Massive gabapentin and presumptive quetiapine overdose.
Topics: Acetates; Amines; Anti-Anxiety Agents; Antipsychotic Agents; Coma; Cyclohexanecarboxylic Acids; Dibe | 2002 |
Decompensated hemorrhage activates serotonergic neurons in the subependymal parapyramidal region of the rat medulla.
Topics: Animals; Blood Pressure; Enkephalins; gamma-Aminobutyric Acid; Heart Rate; Hydralazine; Hypotension; | 2002 |
Involvement of gamma-aminobutyric acid (GABA) B receptors in the hypotensive effect of systemically administered GABA in spontaneously hypertensive rats.
Topics: Animals; Dose-Response Relationship, Drug; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; ga | 2002 |
Relationship between the hypotensive activity and chemical structure of gamma-aminobutyric acid in the rabbit.
Topics: Amino Acids; Animals; Blood Pressure; Blood Pressure Determination; gamma-Aminobutyric Acid; Heart; | 1962 |
CENTRAL CARDIOVASCULAR ACTIONS OF GAMMA-AMINOBUTYRIC ACID.
Topics: Aminobutyrates; Animals; Bradycardia; Cats; Dogs; gamma-Aminobutyric Acid; Heart; Heart Rate; Hypote | 1964 |
Phytochemical and pharmacological studies on Viscum album L. III. Isolation of a hypotensive substance: gamma-aminobutyric acid.
Topics: Amino Acids; Antihypertensive Agents; Biological Products; gamma-Aminobutyric Acid; Hypotension; Vis | 1959 |
Gabapentin-induced hypoglycemia in a long-term peritoneal dialysis patient.
Topics: Acetates; Amines; C-Peptide; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Aci | 2003 |
Profiles in patient safety: when an error occurs.
Topics: Acetates; Aged; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Diabetic Neuropath | 2004 |
Prolonged moderate hypothermia in massive hemispheric infarction: clinical experience.
Topics: Adult; Cerebral Infarction; Female; gamma-Aminobutyric Acid; Humans; Hypotension; Hypothermia, Induc | 2005 |
Central nervous system mechanisms involving GABA influence arterial pressure and heart rate in the cat.
Topics: Animals; Autonomic Nervous System; Blood Pressure; Bradycardia; Cats; Central Nervous System; Clonid | 1980 |
Preferential hindquarter vasodilation in the hypotension induced by GABA injection into the cisterna magna of conscious rats.
Topics: Animals; Blood Pressure; Bradycardia; gamma-Aminobutyric Acid; Heart Rate; Hypotension; Male; Rats; | 1993 |
Hemodialysis and hemoperfusion for treatment of valproic acid and gabapentin poisoning.
Topics: Acetates; Adult; Amines; Anticonvulsants; Biomarkers; Blood Chemical Analysis; Chromatography, Thin | 1996 |
GABA may function tonically via GABA(A) receptors to inhibit hypotension and bradycardia by L-DOPA microinjected into depressor sites of the nucleus tractus solitarii in anesthetized rats.
Topics: Anesthesia; Animals; Bicuculline; Binding, Competitive; Bradycardia; Dopamine Agents; Dose-Response | 1999 |
Overexpression of eNOS in the RVLM causes hypotension and bradycardia via GABA release.
Topics: Adenoviridae; Animals; beta-Galactosidase; Blood Pressure; Bradycardia; Enzyme Inhibitors; gamma-Ami | 2001 |
GABA(A) receptor activation at medullary sympathetic neurons contributes to postexercise hypotension.
Topics: Animals; Baroreflex; Bicuculline; Blood Pressure; GABA Agonists; GABA Antagonists; GABA-A Receptor A | 2002 |
[An analysis of the discrepancy between the effects of central and peripheral alpha-adrenoceptor stimulations (author's transl)].
Topics: Animals; Clonidine; gamma-Aminobutyric Acid; Hypotension; Picrotoxin; Rabbits; Receptors, Adrenergic | 1979 |
Hypotension decreases GABA levels in brainstem regions of the rat.
Topics: Alanine; Animals; Blood Pressure; Brain Stem; gamma-Aminobutyric Acid; Ganglionic Blockers; Glycine; | 1990 |
Effect of a brief hypoxic/hypotensive episode on the in vivo release of cerebral cortical gamma-aminobutyric acid and glycine.
Topics: Animals; Cerebral Cortex; gamma-Aminobutyric Acid; Glycine; Hypotension; Hypoxia, Brain; Male; Rats; | 1989 |
Biochemical evidence for the GABA regulation of vasopressin levels in microdissected brain structures after servo-controlled hypotension.
Topics: 3-Mercaptopropionic Acid; Animals; Brain; Enzyme Inhibitors; gamma-Aminobutyric Acid; Hypotension; M | 1989 |
Hypotension and hypothalamic depression produced by intracerebroventricular injections of GABA in spontaneously hypertensive rats.
Topics: Animals; gamma-Aminobutyric Acid; Hemodynamics; Hypotension; Hypothalamus; Injections, Intraventricu | 1986 |