gamma-aminobutyric acid has been researched along with Hyperactivity, Motor in 39 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Environmental factors have been associated with psychiatric disorders and recent epidemiological studies suggest an association between prenatal lead (Pb(2+)) exposure and schizophrenia (SZ)." | 7.81 | Early-life lead exposure recapitulates the selective loss of parvalbumin-positive GABAergic interneurons and subcortical dopamine system hyperactivity present in schizophrenia. ( Guilarte, TR; Liu, X; McGlothan, JL; Ruby, KN; Soares, BD; Stansfield, KH, 2015) |
| "Environmental factors have been associated with psychiatric disorders and recent epidemiological studies suggest an association between prenatal lead (Pb(2+)) exposure and schizophrenia (SZ)." | 3.81 | Early-life lead exposure recapitulates the selective loss of parvalbumin-positive GABAergic interneurons and subcortical dopamine system hyperactivity present in schizophrenia. ( Guilarte, TR; Liu, X; McGlothan, JL; Ruby, KN; Soares, BD; Stansfield, KH, 2015) |
| "Wistar rat pups were administered either a high dose of lead acetate (400 micrograms lead/g body weight/day) or a low dose (100 micrograms lead/g body weight/day) by gastric intubation, from 2 days through 60 days of age." | 3.68 | Regional alterations of brain biogenic amines and GABA/glutamate levels in rats following chronic lead exposure during neonatal development. ( Desiraju, T; Shailesh Kumar, MV, 1990) |
| "Fipronil is an insecticide widely used for veterinary and agricultural purposes." | 1.56 | Long-Term Fipronil Treatment Induces Hyperactivity in Female Mice. ( Auvray, P; Blondel, M; Koslowski, S; Latapy, C; Meijer, L, 2020) |
| "At AA 44-46 weeks, the frequency of sleep disorders decreased to 45,45% (p=0,012) and 52,63% (p=0,05)." | 1.40 | [Clinical and neurophysiological objectification and evaluation of treatment efficacy in children with perinatal hypoxic-ischemic injury of the CNS]. ( Degtiareva, MG; Grebennikova, OV; Medvedev, MI; Rogatkin, SO; Zavadenko, AN, 2014) |
| "The treatment reduced sleep disorders, changed the duration of transitional sleep stage and latent period of the 2nd stage of slow wave sleep." | 1.40 | [Clinical and neurophysiological objectification and evaluation of treatment efficacy in children with perinatal hypoxic-ischemic injury of the CNS]. ( Degtiareva, MG; Grebennikova, OV; Medvedev, MI; Rogatkin, SO; Zavadenko, AN, 2014) |
| "Planarian hyperkinesias behavior counting experiments also revealed that riluzole (0." | 1.39 | Riluzole attenuates the effects of chemoconvulsants acting on glutamatergic and GABAergic neurotransmission in the planarian Dugesia tigrina. ( Dalhoff, Z; Eggerichs, MR; Elshikh, AH; Fettig, SL; Karki, P; Nelson, BE; Ramakrishnan, L; Shrestha, B, 2013) |
| "In summary, arvanil does alleviate hyperkinesia typical of HD, although it also affects locomotion in normal rats." | 1.33 | Arvanil, a hybrid endocannabinoid and vanilloid compound, behaves as an antihyperkinetic agent in a rat model of Huntington's disease. ( de Lago, E; Di Marzo, V; Fernández-Ruiz, J; Ramos, JA; Urbani, P, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (20.51) | 18.7374 |
| 1990's | 2 (5.13) | 18.2507 |
| 2000's | 15 (38.46) | 29.6817 |
| 2010's | 13 (33.33) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Koslowski, S | 1 |
| Latapy, C | 1 |
| Auvray, P | 1 |
| Blondel, M | 1 |
| Meijer, L | 1 |
| Fan, HR | 1 |
| Du, WF | 1 |
| Zhu, T | 2 |
| Wu, YJ | 1 |
| Liu, YM | 1 |
| Wang, Q | 2 |
| Gu, X | 1 |
| Shan, X | 1 |
| Deng, S | 1 |
| Xu, TL | 1 |
| Ge, WH | 1 |
| Li, WG | 1 |
| Li, F | 1 |
| Ramakrishnan, L | 1 |
| Dalhoff, Z | 1 |
| Fettig, SL | 1 |
| Eggerichs, MR | 1 |
| Nelson, BE | 1 |
| Shrestha, B | 1 |
| Elshikh, AH | 1 |
| Karki, P | 1 |
| Dougherty, SE | 1 |
| Hollimon, JJ | 1 |
| McMeekin, LJ | 1 |
| Bohannon, AS | 1 |
| West, AB | 1 |
| Lesort, M | 1 |
| Hablitz, JJ | 1 |
| Cowell, RM | 1 |
| Grebennikova, OV | 1 |
| Zavadenko, AN | 1 |
| Rogatkin, SO | 1 |
| Medvedev, MI | 1 |
| Degtiareva, MG | 1 |
| Stansfield, KH | 1 |
| Ruby, KN | 1 |
| Soares, BD | 1 |
| McGlothan, JL | 1 |
| Liu, X | 1 |
| Guilarte, TR | 1 |
| Han, Q | 1 |
| Cao, C | 1 |
| Ding, Y | 1 |
| So, KF | 1 |
| Wu, W | 1 |
| Qu, Y | 1 |
| Zhou, L | 1 |
| Greenberg, GD | 1 |
| Crabbe, JC | 1 |
| Belforte, JE | 1 |
| Zsiros, V | 1 |
| Sklar, ER | 1 |
| Jiang, Z | 1 |
| Yu, G | 1 |
| Li, Y | 1 |
| Quinlan, EM | 1 |
| Nakazawa, K | 1 |
| Sukhotina, NK | 1 |
| Konovalova, VV | 1 |
| Kryzhanovskaia, IL | 1 |
| Kupriianova, TA | 1 |
| Wierońska, JM | 1 |
| Kusek, M | 1 |
| Tokarski, K | 1 |
| Wabno, J | 1 |
| Froestl, W | 1 |
| Pilc, A | 1 |
| Katunina, EA | 1 |
| Malykhina, EA | 1 |
| Avanesova, OV | 1 |
| Makarova, AA | 1 |
| Abdurakhmanova, EK | 1 |
| Gridiakin, VI | 1 |
| Han, W | 1 |
| Wang, F | 2 |
| Qi, J | 1 |
| Zhang, L | 1 |
| Zhao, S | 1 |
| Song, M | 1 |
| Wu, C | 1 |
| Yang, J | 1 |
| Han, S | 1 |
| Tai, C | 1 |
| Westenbroek, RE | 1 |
| Yu, FH | 1 |
| Cheah, CS | 1 |
| Potter, GB | 1 |
| Rubenstein, JL | 1 |
| Scheuer, T | 1 |
| de la Iglesia, HO | 1 |
| Catterall, WA | 1 |
| Lastres-Becker, I | 2 |
| de Miguel, R | 2 |
| De Petrocellis, L | 1 |
| Makriyannis, A | 1 |
| Di Marzo, V | 2 |
| Fernández-Ruiz, J | 3 |
| Fedrowitz, M | 1 |
| Lindemann, S | 1 |
| Löscher, W | 1 |
| Gernert, M | 1 |
| Mena-Segovia, J | 1 |
| Favila, R | 1 |
| Giordano, M | 1 |
| Pothuizen, HH | 1 |
| Jongen-Rêlo, AL | 1 |
| Feldon, J | 1 |
| de Lago, E | 1 |
| Urbani, P | 1 |
| Ramos, JA | 2 |
| Miranda-Contreras, L | 1 |
| Dávila-Ovalles, R | 1 |
| Benítez-Díaz, P | 1 |
| Peña-Contreras, Z | 1 |
| Palacios-Prü, E | 1 |
| Vacher, CM | 1 |
| Gassmann, M | 1 |
| Desrayaud, S | 1 |
| Challet, E | 1 |
| Bradaia, A | 1 |
| Hoyer, D | 1 |
| Waldmeier, P | 1 |
| Kaupmann, K | 1 |
| Pévet, P | 1 |
| Bettler, B | 1 |
| Yin, HS | 1 |
| Chen, K | 1 |
| Kalpana, S | 1 |
| Shih, JC | 1 |
| Richards, AB | 1 |
| Scheel, TA | 1 |
| Wang, K | 1 |
| Henkemeyer, M | 1 |
| Kromer, LF | 1 |
| Masuo, Y | 1 |
| Ishido, M | 1 |
| Morita, M | 1 |
| Sawa, H | 1 |
| Nagashima, K | 1 |
| Niki, E | 1 |
| Wray, SR | 1 |
| Melville, GN | 1 |
| Grell, GA | 1 |
| Edge, PC | 1 |
| Costall, B | 1 |
| Domeney, AM | 1 |
| Naylor, RJ | 1 |
| Thiebot, MH | 1 |
| Kloczko, J | 1 |
| Chermat, R | 1 |
| Puech, AJ | 1 |
| Soubrie, P | 1 |
| Simon, P | 1 |
| Iakimovskiĭ, AF | 1 |
| Khisti, RT | 1 |
| Chopde, CT | 1 |
| Abraham, E | 1 |
| Ishiguro, Y | 1 |
| Kajita, M | 1 |
| Aoshima, T | 1 |
| Watanabe, K | 1 |
| Kimura, M | 1 |
| Yamaguchi, S | 1 |
| Chang, CK | 1 |
| Lin, MT | 1 |
| Nishimura, T | 1 |
| Schwarzer, C | 1 |
| Furtinger, S | 1 |
| Imai, H | 1 |
| Kato, N | 1 |
| Sperk, G | 1 |
| Hansen, HH | 1 |
| Berrendero, F | 1 |
| Pérez-Rosado, A | 1 |
| Manzanares, J | 1 |
| Pycock, CJ | 1 |
| Horton, RW | 1 |
| Green, AR | 1 |
| Tordoff, AF | 1 |
| Bloomfield, MR | 1 |
| Shailesh Kumar, MV | 1 |
| Desiraju, T | 1 |
| Mondrup, K | 1 |
| Dupont, E | 1 |
| Braendgaard, H | 1 |
| Soyka, D | 1 |
| Sazonova, NS | 1 |
| Balashova, EG | 1 |
2 reviews available for gamma-aminobutyric acid and Hyperactivity, Motor
| Article | Year |
|---|---|
Gene Targeting Studies of Hyperexcitability and Affective States of Alcohol Withdrawal in Rodents.
Topics: Alcoholism; Animals; Animals, Genetically Modified; Disease Models, Animal; Epilepsy; gamma-Aminobut | 2016 |
Current concepts of abnormal motor disorder: an experimental model of attentional deficit disorder.
Topics: Amphetamine; Animals; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Avoidance | 1981 |
1 trial available for gamma-aminobutyric acid and Hyperactivity, Motor
| Article | Year |
|---|---|
[Efficacy of pantogam in the treatment of hyperkinetic disorders in children].
Topics: Child; Female; gamma-Aminobutyric Acid; Humans; Hyperkinesis; Male; Nootropic Agents; Pantothenic Ac | 2010 |
36 other studies available for gamma-aminobutyric acid and Hyperactivity, Motor
| Article | Year |
|---|---|
Long-Term Fipronil Treatment Induces Hyperactivity in Female Mice.
Topics: Animals; Female; gamma-Aminobutyric Acid; Hyperkinesis; Insecticides; Mice; Pyrazoles; Receptors, GA | 2020 |
Quercetin Reduces Cortical GABAergic Transmission and Alleviates MK-801-Induced Hyperactivity.
Topics: Animals; Antipsychotic Agents; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonis | 2018 |
Riluzole attenuates the effects of chemoconvulsants acting on glutamatergic and GABAergic neurotransmission in the planarian Dugesia tigrina.
Topics: Animals; Behavior, Animal; Convulsants; Dizocilpine Maleate; Excitatory Amino Acid Agonists; gamma-A | 2013 |
Hyperactivity and cortical disinhibition in mice with restricted expression of mutant huntingtin to parvalbumin-positive cells.
Topics: Age Factors; Animals; Brain; Female; gamma-Aminobutyric Acid; Huntingtin Protein; Hyperkinesis; Inhi | 2014 |
[Clinical and neurophysiological objectification and evaluation of treatment efficacy in children with perinatal hypoxic-ischemic injury of the CNS].
Topics: Child; Child, Preschool; Electroencephalography; Female; gamma-Aminobutyric Acid; Humans; Hyperkines | 2014 |
Early-life lead exposure recapitulates the selective loss of parvalbumin-positive GABAergic interneurons and subcortical dopamine system hyperactivity present in schizophrenia.
Topics: Animals; Blotting, Western; Brain; Chromatography, High Pressure Liquid; Dopamine; Female; gamma-Ami | 2015 |
Plasticity of motor network and function in the absence of corticospinal projection.
Topics: Acetylcholine; Animals; Brain Diseases; Cadherins; Choline O-Acetyltransferase; Disease Models, Anim | 2015 |
Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes.
Topics: Action Potentials; Analysis of Variance; Animals; Animals, Newborn; Cerebral Cortex; Disease Models, | 2010 |
The GABA B receptor agonist CGP44532 and the positive modulator GS39783 reverse some behavioural changes related to positive syndromes of psychosis in mice.
Topics: Animals; Behavior, Animal; Catalepsy; Cyclopentanes; Disease Models, Animal; Dose-Response Relations | 2011 |
[Pantogam active in the complex treatment of dystonic hyperkineses].
Topics: Adult; Aged; Drug Therapy, Combination; Face; Female; gamma-Aminobutyric Acid; Humans; Hyperkinesis; | 2010 |
NMDA receptors in the medial prefrontal cortex and the dorsal hippocampus regulate methamphetamine-induced hyperactivity and extracellular amino acid release in mice.
Topics: Amino Acids; Animals; Blotting, Western; Central Nervous System Stimulants; Excitatory Amino Acid Ag | 2012 |
Autistic-like behaviour in Scn1a+/- mice and rescue by enhanced GABA-mediated neurotransmission.
Topics: Animals; Anxiety; Autistic Disorder; Clonazepam; Epilepsies, Myoclonic; GABA Modulators; GABAergic N | 2012 |
Compounds acting at the endocannabinoid and/or endovanilloid systems reduce hyperkinesia in a rat model of Huntington's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids, Neutral; Animals; Arachidonic Acids; Basal Ganglia; Can | 2003 |
Altered spontaneous discharge rate and pattern of basal ganglia output neurons in the circling (ci2) rat mutant.
Topics: Action Potentials; Animals; Basal Ganglia; Basal Ganglia Diseases; Dopamine; Efferent Pathways; Fema | 2003 |
Long-term effects of striatal lesions on c-Fos immunoreactivity in the pedunculopontine nucleus.
Topics: Acetylcholine; Animals; Circadian Rhythm; Corpus Striatum; Denervation; gamma-Aminobutyric Acid; Hyp | 2004 |
The effects of temporary inactivation of the core and the shell subregions of the nucleus accumbens on prepulse inhibition of the acoustic startle reflex and activity in rats.
Topics: Akathisia, Drug-Induced; Animals; Artifacts; Diffusion; GABA Agonists; GABA-A Receptor Agonists; gam | 2005 |
Arvanil, a hybrid endocannabinoid and vanilloid compound, behaves as an antihyperkinetic agent in a rat model of Huntington's disease.
Topics: Animals; Brain Chemistry; Capsaicin; Convulsants; Disease Models, Animal; Dopamine; gamma-Aminobutyr | 2005 |
Effects of prenatal paraquat and mancozeb exposure on amino acid synaptic transmission in developing mouse cerebellar cortex.
Topics: Animals; Aspartic Acid; Cerebellar Cortex; Disease Models, Animal; Down-Regulation; Female; Fungicid | 2005 |
Hyperdopaminergia and altered locomotor activity in GABAB1-deficient mice.
Topics: Animals; Binding Sites; Brain Diseases, Metabolic; Corpus Striatum; Disease Models, Animal; Dopamine | 2006 |
Differential effects of chronic amphetamine and baclofen administration on cAMP levels and phosphorylation of CREB in distinct brain regions of wild type and monoamine oxidase B-deficient mice.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Baclofen; Biogenic Monoamines; Brain; Central N | 2006 |
EphB1 null mice exhibit neuronal loss in substantia nigra pars reticulata and spontaneous locomotor hyperactivity.
Topics: Animals; Basal Ganglia Diseases; beta-Galactosidase; Biomarkers; Cell Death; Cell Differentiation; C | 2007 |
Behavioural characteristics and gene expression in the hyperactive wiggling (Wig) rat.
Topics: Adrenergic Agents; Analysis of Variance; Animals; Animals, Congenic; Animals, Newborn; Behavior, Ani | 2007 |
Locomotor hyperactivity caused by dopamine infusion into the nucleus accumbens of rat brain: specificity of action.
Topics: Acetylcholine; Animals; Catheters, Indwelling; Dopamine; Female; gamma-Aminobutyric Acid; Humans; Hy | 1984 |
Enhancement of cocaine-induced hyperactivity in mice by benzodiazepines: evidence for an interaction of GABAergic processes with catecholaminergic neurons?
Topics: Animals; Benzodiazepines; Catecholamines; Cocaine; Drug Synergism; gamma-Aminobutyric Acid; Humans; | 1981 |
[Myoclonic hyperkinesis induced by repeated administration of picrotoxin into rat neostriatum].
Topics: Animals; Avoidance Learning; gamma-Aminobutyric Acid; Generalization, Stimulus; Hyperkinesis; Male; | 1993 |
GABAergic involvement in motor effects of an adenosine A(2A) receptor agonist in mice.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amphetamine; Animals; Catalepsy; Dopamine Agents; GABA | 2000 |
The first case of 4-hydroxybutyric aciduria in Japan.
Topics: Aldehyde Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Brain; gamma-Aminobutyric Acid; Huma | 2001 |
DL-Tetrahydropalmatine may act through inhibition of amygdaloid release of dopamine to inhibit an epileptic attack in rats.
Topics: Amygdala; Animals; Berberine Alkaloids; Dopamine; Dopamine Antagonists; Epilepsy; GABA Antagonists; | 2001 |
Changes in the GABA-ergic system induced by trimethyltin application in the rat.
Topics: Aggression; Animals; Cell Death; Enzyme Induction; gamma-Aminobutyric Acid; Gene Expression Regulati | 2001 |
Alleviation of motor hyperactivity and neurochemical deficits by endocannabinoid uptake inhibition in a rat model of Huntington's disease.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Cannabinoids; Convulsants; Disease Mode | 2002 |
Dopamine-dependent hyperactivity in the rat following manipulation of GABA mechanisms in the region of the nucleus accumbens.
Topics: Amino Acids; Animals; beta-Alanine; Cyclohexanecarboxylic Acids; Dextroamphetamine; Dopamine; Dose-R | 1979 |
Elevation of brain GABA concentrations with amino-oxyacetic acid; effect on the hyperactivity syndrome produced by increased 5-hydroxytryptamine synthesis in rats.
Topics: Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Brain; Dopamine; gamma-Aminobutyric Acid; Hu | 1976 |
Regional alterations of brain biogenic amines and GABA/glutamate levels in rats following chronic lead exposure during neonatal development.
Topics: Animals; Biogenic Amines; Body Weight; Brain; Dopamine; Dose-Response Relationship, Drug; Female; ga | 1990 |
Progabide in the treatment of hyperkinetic extrapyramidal movement disorders.
Topics: Adolescent; Adult; Aged; Athetosis; Basal Ganglia Diseases; Child; Chorea; Female; gamma-Aminobutyri | 1985 |
[Syndrome involving the extrapyramidal motor systems and their drug treatment].
Topics: Amantadine; Antiparkinson Agents; Basal Ganglia Diseases; Dihydroxyphenylalanine; gamma-Aminobutyric | 1974 |
[Experience with clinical use of the drug gammalon in children with cerebral palsy].
Topics: Adolescent; Aminobutyrates; Cerebral Palsy; Child; Child, Preschool; Electromyography; Feeding and E | 1974 |