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gamma-aminobutyric acid and Heroin Abuse

gamma-aminobutyric acid has been researched along with Heroin Abuse in 9 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Research Excerpts

ExcerptRelevanceReference
"Gabapentin is an antiepileptic drug shown to be effective in the treatment of pain disorders and appears to be useful as well for several psychiatric disorders, including bipolar disorder, anxiety disorders, alcohol withdrawal and cocaine dependence."2.71Add-on gabapentin in the treatment of opiate withdrawal. ( Castellano, M; Cervera, G; Martínez-Raga, J; Perez-Galvez, B; Sabater, A, 2004)
"Problematic compounds may cause seizures either acutely or on withdrawal: Their use may reduce effectiveness of antiepileptic drugs, or may simply promote and enhance chaotic lifestyles."2.48Alcohol and drugs in epilepsy: pathophysiology, presentation, possibilities, and prevention. ( Borland, W; Leach, JP; Mohanraj, R, 2012)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's4 (44.44)29.6817
2010's4 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lyndon, A1
Audrey, S1
Wells, C1
Burnell, ES1
Ingle, S1
Hill, R1
Hickman, M1
Henderson, G1
Van den Oever, MC1
Lubbers, BR1
Goriounova, NA1
Li, KW1
Van der Schors, RC1
Loos, M1
Riga, D1
Wiskerke, J1
Binnekade, R2
Stegeman, M1
Schoffelmeer, AN2
Mansvelder, HD1
Smit, AB1
De Vries, TJ2
Spijker, S1
Kämmerer, N1
Lemenager, T1
Grosshans, M1
Kiefer, F1
Hermann, D1
Leach, JP1
Mohanraj, R1
Borland, W1
Martínez-Raga, J1
Sabater, A1
Perez-Galvez, B1
Castellano, M1
Cervera, G1
Freye, E1
Levy, JV1
Partecke, L1
Xi, ZX1
Wu, G1
Stein, EA1
Li, SJ1
Schmidt, ED1
Voorn, P1
Sell, LA1
Morris, J1
Bearn, J1
Frackowiak, RS1
Friston, KJ1
Dolan, RJ1

Reviews

1 review available for gamma-aminobutyric acid and Heroin Abuse

ArticleYear
Alcohol and drugs in epilepsy: pathophysiology, presentation, possibilities, and prevention.
    Epilepsia, 2012, Volume: 53 Suppl 4

    Topics: Alcohol Drinking; Alcohol Withdrawal Seizures; Alcoholism; Amphetamine-Related Disorders; Benzodiaze

2012

Trials

2 trials available for gamma-aminobutyric acid and Heroin Abuse

ArticleYear
Add-on gabapentin in the treatment of opiate withdrawal.
    Progress in neuro-psychopharmacology & biological psychiatry, 2004, Volume: 28, Issue:3

    Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gab

2004
Use of gabapentin for attenuation of symptoms following rapid opiate detoxification (ROD)--correlation with neurophysiological parameters--.
    Neurophysiologie clinique = Clinical neurophysiology, 2004, Volume: 34, Issue:2

    Topics: Acetates; Adult; Amines; Anesthesia; Anesthetics, Intravenous; Cyclohexanecarboxylic Acids; Electric

2004

Other Studies

6 other studies available for gamma-aminobutyric acid and Heroin Abuse

ArticleYear
Risk to heroin users of polydrug use of pregabalin or gabapentin.
    Addiction (Abingdon, England), 2017, Volume: 112, Issue:9

    Topics: Adult; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Intera

2017
Extracellular matrix plasticity and GABAergic inhibition of prefrontal cortex pyramidal cells facilitates relapse to heroin seeking.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:10

    Topics: Animals; Chromatography, High Pressure Liquid; Conditioning, Operant; Cues; Drug Administration Sche

2010
[Pregabalin for the reduction of opiate withdrawal symptoms].
    Psychiatrische Praxis, 2012, Volume: 39, Issue:7

    Topics: Adult; Anticonvulsants; Drug Administration Schedule; gamma-Aminobutyric Acid; Heroin Dependence; Hu

2012
Opiate tolerance by heroin self-administration: an fMRI study in rat.
    Magnetic resonance in medicine, 2004, Volume: 52, Issue:1

    Topics: Animals; Brain; Drug Tolerance; gamma-Aminobutyric Acid; Heroin; Heroin Dependence; Magnetic Resonan

2004
Differential involvement of the prelimbic cortex and striatum in conditioned heroin and sucrose seeking following long-term extinction.
    The European journal of neuroscience, 2005, Volume: 22, Issue:9

    Topics: Analysis of Variance; Animals; Behavior, Animal; Cell Count; Cerebral Cortex; Conditioning, Operant;

2005
Activation of reward circuitry in human opiate addicts.
    The European journal of neuroscience, 1999, Volume: 11, Issue:3

    Topics: Adult; Brain Chemistry; Brain Stem; gamma-Aminobutyric Acid; Heroin; Heroin Dependence; Humans; Inte

1999