gamma-aminobutyric acid has been researched along with Heart Failure in 18 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results of this review will assist physicians to better appreciate pregabalin's risk for edema or congestive heart failure and will be pertinent to the thousands of patients worldwide who are administered this medication." | 8.89 | Risk of heart failure and edema associated with the use of pregabalin: a systematic review. ( Chen, M; Ho, JM; Juurlink, DN; Perrier, L; Straus, SE; Tricco, AC, 2013) |
| "In a large cohort of older patients with a seizure disorder, pregabalin was not associated with an increased risk of heart failure relative to gabapentin." | 7.85 | Pregabalin and heart failure: A population-based study. ( Antoniou, T; Gomes, T; Ho, JM; Juurlink, DN; Luo, J; Macdonald, EM; Mamdani, MM, 2017) |
| "The anticonvulsant pregabalin is increasingly prescribed for pain, seizures, and psychiatric disorders." | 7.85 | Pregabalin and heart failure: A population-based study. ( Antoniou, T; Gomes, T; Ho, JM; Juurlink, DN; Luo, J; Macdonald, EM; Mamdani, MM, 2017) |
| "The results of this review will assist physicians to better appreciate pregabalin's risk for edema or congestive heart failure and will be pertinent to the thousands of patients worldwide who are administered this medication." | 4.89 | Risk of heart failure and edema associated with the use of pregabalin: a systematic review. ( Chen, M; Ho, JM; Juurlink, DN; Perrier, L; Straus, SE; Tricco, AC, 2013) |
| "In patients with diabetic neuropathy who were prescribed gabapentin and pregabalin, there is an increased risk for heart failure, myocardial infarction, peripheral vascular disease, stroke, deep venous thrombosis, and pulmonary embolism with long-term use." | 4.12 | Cardiovascular risk of gabapentin and pregabalin in patients with diabetic neuropathy. ( Blankfield, RP; Davis, PB; Kaebler, DC; Pan, Y; Xu, R, 2022) |
| "Gabapentin and pregabalin are commonly prescribed medications to treat pain in patients with diabetic neuropathy." | 4.12 | Cardiovascular risk of gabapentin and pregabalin in patients with diabetic neuropathy. ( Blankfield, RP; Davis, PB; Kaebler, DC; Pan, Y; Xu, R, 2022) |
| "In a large cohort of older patients with a seizure disorder, pregabalin was not associated with an increased risk of heart failure relative to gabapentin." | 3.85 | Pregabalin and heart failure: A population-based study. ( Antoniou, T; Gomes, T; Ho, JM; Juurlink, DN; Luo, J; Macdonald, EM; Mamdani, MM, 2017) |
| "The anticonvulsant pregabalin is increasingly prescribed for pain, seizures, and psychiatric disorders." | 3.85 | Pregabalin and heart failure: A population-based study. ( Antoniou, T; Gomes, T; Ho, JM; Juurlink, DN; Luo, J; Macdonald, EM; Mamdani, MM, 2017) |
| " The case presentation illustrates the role of pregabalin in successful medical management of this chronic pain disorder, as well as the management of common psychiatric morbidities associated with this condition." | 3.74 | Pregabalin-induced remission in a 62-year-old woman with a 20-year history of vulvodynia. ( Jerome, L, 2007) |
| " However, whether long-term use of gabapentin and pregabalin is associated with adverse cardiovascular diseases remains unknown." | 1.72 | Cardiovascular risk of gabapentin and pregabalin in patients with diabetic neuropathy. ( Blankfield, RP; Davis, PB; Kaebler, DC; Pan, Y; Xu, R, 2022) |
| "Muscimol was also less effective in decreasing RSND, BP, and HR in HF rats than in control rats." | 1.31 | Reduced endogenous GABA-mediated inhibition in the PVN on renal nerve discharge in rats with heart failure. ( Li, YF; Patel, KP; Zhang, K, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (50.00) | 29.6817 |
| 2010's | 8 (44.44) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Pan, Y | 1 |
| Davis, PB | 1 |
| Kaebler, DC | 1 |
| Blankfield, RP | 1 |
| Xu, R | 1 |
| Ho, JM | 2 |
| Macdonald, EM | 1 |
| Luo, J | 1 |
| Gomes, T | 1 |
| Antoniou, T | 1 |
| Mamdani, MM | 1 |
| Juurlink, DN | 2 |
| Tricco, AC | 1 |
| Perrier, L | 1 |
| Chen, M | 1 |
| Straus, SE | 1 |
| Pfisterer, M | 1 |
| Liu, Q | 1 |
| Wang, T | 1 |
| Yu, H | 1 |
| Liu, B | 1 |
| Jia, R | 1 |
| Pandit, S | 2 |
| Jo, JY | 1 |
| Lee, SU | 1 |
| Lee, YJ | 1 |
| Lee, SY | 1 |
| Ryu, PD | 1 |
| Lee, JU | 1 |
| Kim, HW | 2 |
| Jeon, BH | 1 |
| Park, JB | 2 |
| Cauley, E | 1 |
| Wang, X | 1 |
| Dyavanapalli, J | 1 |
| Sun, K | 1 |
| Garrott, K | 1 |
| Kuzmiak-Glancy, S | 1 |
| Kay, MW | 1 |
| Mendelowitz, D | 1 |
| De Smedt, RH | 1 |
| Jaarsma, T | 1 |
| van den Broek, SA | 1 |
| Haaijer-Ruskamp, FM | 1 |
| Page, RL | 1 |
| Cantu, M | 1 |
| Lindenfeld, J | 1 |
| Hergott, LJ | 1 |
| Lowes, BD | 1 |
| Erdoğan, G | 1 |
| Ceyhan, D | 1 |
| Güleç, S | 1 |
| Patel, KP | 2 |
| Laustsen, G | 1 |
| Gilbert, M | 1 |
| Wimett, L | 1 |
| Murphy, N | 1 |
| Mockler, M | 1 |
| Ryder, M | 1 |
| Ledwidge, M | 1 |
| McDonald, K | 1 |
| Jerome, L | 1 |
| Laville, MA | 1 |
| de la Gastine, B | 1 |
| Husson, B | 1 |
| Le Boisselier, R | 1 |
| Mosquet, B | 1 |
| Coquerel, A | 1 |
| Belgrade, M | 1 |
| Zhang, K | 1 |
| Li, YF | 1 |
3 reviews available for gamma-aminobutyric acid and Heart Failure
| Article | Year |
|---|---|
Risk of heart failure and edema associated with the use of pregabalin: a systematic review.
Topics: Edema; gamma-Aminobutyric Acid; Heart Failure; Humans; Outcome Assessment, Health Care; Pregabalin; | 2013 |
Possible heart failure exacerbation associated with pregabalin: case discussion and literature review.
Topics: Aged; Analgesics; Female; gamma-Aminobutyric Acid; Heart Failure; Humans; Male; Middle Aged; Neuralg | 2008 |
Role of paraventricular nucleus in mediating sympathetic outflow in heart failure.
Topics: Animals; Cardiac Output, Low; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Heart; Heart | 2000 |
15 other studies available for gamma-aminobutyric acid and Heart Failure
| Article | Year |
|---|---|
Cardiovascular risk of gabapentin and pregabalin in patients with diabetic neuropathy.
Topics: Amines; Analgesics; Cardiovascular Diseases; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gab | 2022 |
Pregabalin and heart failure: A population-based study.
Topics: Aged; Aged, 80 and over; Amines; Anticonvulsants; Calcium Channel Blockers; Cohort Studies; Cyclohex | 2017 |
[Palliative care in geriatrics].
Topics: Alzheimer Disease; Analgesics; Cooperative Behavior; gamma-Aminobutyric Acid; Geriatrics; Germany; H | 2013 |
Interaction between interleukin-1 beta and angiotensin II receptor 1 in hypothalamic paraventricular nucleus contributes to progression of heart failure.
Topics: Animals; Corticotropin-Releasing Hormone; Disease Models, Animal; Disease Progression; gamma-Aminobu | 2014 |
Enhanced astroglial GABA uptake attenuates tonic GABAA inhibition of the presympathetic hypothalamic paraventricular nucleus neurons in heart failure.
Topics: Action Potentials; Animals; Astrocytes; Disease Models, Animal; GABA Plasma Membrane Transport Prote | 2015 |
Enhanced astroglial GABA uptake in heart failure.
Topics: Animals; Astrocytes; gamma-Aminobutyric Acid; Heart Failure; Male; Neurons; Paraventricular Hypothal | 2015 |
Neurotransmission to parasympathetic cardiac vagal neurons in the brain stem is altered with left ventricular hypertrophy-induced heart failure.
Topics: Animals; Brain Stem; Disease Models, Animal; Excitatory Postsynaptic Potentials; GABAergic Neurons; | 2015 |
Decompensation of chronic heart failure associated with pregabalin in a 73-year-old patient with postherpetic neuralgia: a case report.
Topics: Aged; Anticonvulsants; Bumetanide; Chronic Disease; gamma-Aminobutyric Acid; Heart Failure; Herpes Z | 2008 |
Possible heart failure associated with pregabalin use: case report.
Topics: Amines; Analgesics; Back Pain; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Edema; Female; | 2011 |
A look back at the most influential drug approvals of 2005.
Topics: Amyloid; Analgesics; Anticonvulsants; Antiparkinson Agents; Diabetes Mellitus, Type 2; Diphtheria-Te | 2006 |
Decompensation of chronic heart failure associated with pregabalin in patients with neuropathic pain.
Topics: Aged; Anticonvulsants; gamma-Aminobutyric Acid; Heart Failure; Humans; Male; Middle Aged; Neuralgia; | 2007 |
Pregabalin-induced remission in a 62-year-old woman with a 20-year history of vulvodynia.
Topics: Amitriptyline; Analgesics; Anti-Ulcer Agents; Anticoagulants; Antidepressive Agents; Anxiety; Cardio | 2007 |
[Should we care about pregabalin for elderly patients with a history of cardiac dysrhythmia?].
Topics: Aged, 80 and over; Amines; Analgesics; Atrial Fibrillation; Cyclohexanecarboxylic Acids; Female; Gab | 2008 |
Postherpetic pain control with concomitant illness?
Topics: Acetates; Aged; Aged, 80 and over; Amines; Analgesics; Analgesics, Opioid; Biological Availability; | 2001 |
Reduced endogenous GABA-mediated inhibition in the PVN on renal nerve discharge in rats with heart failure.
Topics: Animals; Bicuculline; Blood Pressure; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hear | 2002 |