gamma-aminobutyric acid has been researched along with HIV Coinfection in 16 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Excerpt | Relevance | Reference |
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"The objective of this study was to assess the efficacy and safety of Gabapentin as the sole analgesic in patients with HIV-related painful neuropathy." | 7.71 | Gabapentin in painful HIV-related neuropathy: a report of 19 patients, preliminary observations. ( Bottura, P; La Spina, I; Maggiolo, F; Porazzi, D; Suter, F, 2001) |
"Neuropathic pain is commonly associated with affective disorders such as anxiety and depression." | 5.35 | Anxiety-like behaviour is attenuated by gabapentin, morphine and diazepam in a rodent model of HIV anti-retroviral-associated neuropathic pain. ( Blackbeard, J; Pheby, T; Rice, AS; Segerdahl, AR; Wallace, VC, 2008) |
" Two distinct FAAH inhibitory compounds, URB597 and PF-3845 were tested, and contrasted with standard antinociceptive gabapentin or vehicle treatment, for attenuation of tactile allodynia, cold allodynia, and mechanical hyperalgesia." | 3.81 | Attenuation of persistent pain-related behavior by fatty acid amide hydrolase (FAAH) inhibitors in a rat model of HIV sensory neuropathy. ( Jergova, S; Nasirinezhad, F; Pearson, JP; Sagen, J, 2015) |
"The objective of this study was to assess the efficacy and safety of Gabapentin as the sole analgesic in patients with HIV-related painful neuropathy." | 3.71 | Gabapentin in painful HIV-related neuropathy: a report of 19 patients, preliminary observations. ( Bottura, P; La Spina, I; Maggiolo, F; Porazzi, D; Suter, F, 2001) |
" Pregabalin average daily dosage (SD) was 385." | 2.75 | Pregabalin for painful HIV neuropathy: a randomized, double-blind, placebo-controlled trial. ( Clifford, DB; Durso-De Cruz, E; Emir, B; Freeman, R; Glue, P; Murphy, TK; Schifitto, G; Scott, GN; Simpson, DM; Whalen, E, 2010) |
"Pregabalin is effective in several neuropathic pain syndromes." | 2.75 | Pregabalin for painful HIV neuropathy: a randomized, double-blind, placebo-controlled trial. ( Clifford, DB; Durso-De Cruz, E; Emir, B; Freeman, R; Glue, P; Murphy, TK; Schifitto, G; Scott, GN; Simpson, DM; Whalen, E, 2010) |
"Treatment with gabapentin, but not amitriptyline, was associated with a complete attenuation of hind paw mechanical hypersensitivity observed with indinavir treatment." | 1.46 | A rodent model of HIV protease inhibitor indinavir induced peripheral neuropathy. ( Bennett, DLH; Calvo, M; Huang, W; Pheby, T; Rice, ASC, 2017) |
"It often presents with significant neuropathic pain and is associated with previous exposure to neurotoxic nucleoside reverse transcriptase inhibitors." | 1.46 | A rodent model of HIV protease inhibitor indinavir induced peripheral neuropathy. ( Bennett, DLH; Calvo, M; Huang, W; Pheby, T; Rice, ASC, 2017) |
" In this study, we tested the hypothesis that HIV gp120 combined with antiretroviral therapy reduces spinal GABAergic inhibitory tone and that restoration of GABAergic inhibitory tone will reduce HIV-related NP in a rat model." | 1.42 | Gene Transfer of Glutamic Acid Decarboxylase 67 by Herpes Simplex Virus Vectors Suppresses Neuropathic Pain Induced by Human Immunodeficiency Virus gp120 Combined with ddC in Rats. ( Candiotti, KA; Hao, S; Huang, W; Kanao, M; Kanda, H; Levitt, RC; Liu, S; Lubarsky, DA; Yi, H, 2015) |
"Spinal epidural lipomatosis is a rare condition of adipose tissue hypertrophy in the epidural space." | 1.38 | Epidural lipomatosis causing new debilitating back pain in a patient with human immunodeficiency virus on highly active antiretroviral therapy. ( Billings, F; Hoyt, MR, 2012) |
"Epidural lipomatosis was diagnosed by magnetic resonance imaging." | 1.38 | Epidural lipomatosis causing new debilitating back pain in a patient with human immunodeficiency virus on highly active antiretroviral therapy. ( Billings, F; Hoyt, MR, 2012) |
"Neuropathic pain is commonly associated with affective disorders such as anxiety and depression." | 1.35 | Anxiety-like behaviour is attenuated by gabapentin, morphine and diazepam in a rodent model of HIV anti-retroviral-associated neuropathic pain. ( Blackbeard, J; Pheby, T; Rice, AS; Segerdahl, AR; Wallace, VC, 2008) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 5 (31.25) | 18.2507 |
2000's | 4 (25.00) | 29.6817 |
2010's | 7 (43.75) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Asundi, A | 1 |
Robles, Y | 1 |
Starr, T | 1 |
Landay, A | 1 |
Kinslow, J | 1 |
Ladner, J | 1 |
White, L | 1 |
Plank, RM | 1 |
Melbourne, K | 1 |
Weisholtz, D | 1 |
Bennett, M | 1 |
Pan, H | 1 |
Stern, E | 1 |
Lin, A | 1 |
Kuritzkes, DR | 1 |
Lin, NH | 1 |
Nasirinezhad, F | 1 |
Jergova, S | 1 |
Pearson, JP | 1 |
Sagen, J | 1 |
Kanao, M | 1 |
Kanda, H | 1 |
Huang, W | 2 |
Liu, S | 1 |
Yi, H | 1 |
Candiotti, KA | 1 |
Lubarsky, DA | 1 |
Levitt, RC | 1 |
Hao, S | 1 |
Calvo, M | 1 |
Pheby, T | 2 |
Bennett, DLH | 1 |
Rice, ASC | 1 |
Wallace, VC | 1 |
Segerdahl, AR | 1 |
Blackbeard, J | 1 |
Rice, AS | 1 |
Terbach, N | 1 |
Williams, RS | 1 |
Simpson, DM | 1 |
Schifitto, G | 1 |
Clifford, DB | 1 |
Murphy, TK | 1 |
Durso-De Cruz, E | 1 |
Glue, P | 1 |
Whalen, E | 1 |
Emir, B | 1 |
Scott, GN | 1 |
Freeman, R | 1 |
Wiersinga, WJ | 1 |
Prins, JM | 1 |
van de Beek, D | 1 |
Billings, F | 1 |
Hoyt, MR | 1 |
Banakar, S | 1 |
Thomas, MA | 1 |
Deveikis, A | 1 |
Watzl, JQ | 1 |
Hayes, J | 1 |
Keller, MA | 1 |
Skolnick, AA | 1 |
Manack, L | 1 |
Rosner, H | 1 |
Rubin, L | 1 |
Kestenbaum, A | 1 |
Newshan, G | 1 |
Vadivelu, N | 1 |
Berger, J | 1 |
Peña, D | 1 |
Prada, JL | 1 |
de La Torre, J | 1 |
del Arco, A | 1 |
García-Alegría, J | 1 |
La Spina, I | 1 |
Porazzi, D | 1 |
Maggiolo, F | 1 |
Bottura, P | 1 |
Suter, F | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
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Persistent Postoperative Pain Incidence With Long Term Perioperative Gabapentin Used[NCT02693821] | Phase 4 | 122 participants (Actual) | Interventional | 2015-12-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
2 reviews available for gamma-aminobutyric acid and HIV Coinfection
Article | Year |
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Structure-function studies for the panacea, valproic acid.
Topics: Animals; Anticonvulsants; Bipolar Disorder; Epilepsy; gamma-Aminobutyric Acid; Glycogen Synthase Kin | 2009 |
[Gabapentin in the treatment of polyneuropathy associated with the human immunodeficiency virus].
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric | 1999 |
2 trials available for gamma-aminobutyric acid and HIV Coinfection
Article | Year |
---|---|
Pregabalin for painful HIV neuropathy: a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Analgesics; Analysis of Variance; Double-Blind Method; Female; Follow-Up Studies; gamma-Amino | 2010 |
Gabapentin adjunctive therapy in neuropathic pain states.
Topics: Acetates; Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Facial Pain; Female; Gabapen | 1996 |
12 other studies available for gamma-aminobutyric acid and HIV Coinfection
Article | Year |
---|---|
Immunological and Neurometabolite Changes Associated With Switch From Efavirenz to an Integrase Inhibitor.
Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Biomarkers; Boston; Central Nervous System; Cycloprop | 2019 |
Attenuation of persistent pain-related behavior by fatty acid amide hydrolase (FAAH) inhibitors in a rat model of HIV sensory neuropathy.
Topics: Amidohydrolases; Amines; Analgesics; Animals; Benzamides; Carbamates; Cyclohexanecarboxylic Acids; D | 2015 |
Gene Transfer of Glutamic Acid Decarboxylase 67 by Herpes Simplex Virus Vectors Suppresses Neuropathic Pain Induced by Human Immunodeficiency Virus gp120 Combined with ddC in Rats.
Topics: Animals; CCAAT-Enhancer-Binding Protein-beta; Cyclic AMP Response Element-Binding Protein; Decarboxy | 2015 |
A rodent model of HIV protease inhibitor indinavir induced peripheral neuropathy.
Topics: Amines; Analgesics; Animals; Calcitonin Gene-Related Peptide; Calcium-Binding Proteins; Cyclohexanec | 2017 |
Anxiety-like behaviour is attenuated by gabapentin, morphine and diazepam in a rodent model of HIV anti-retroviral-associated neuropathic pain.
Topics: Amines; Analgesics; Animal Diseases; Animals; Anxiety; Behavior, Animal; Cyclohexanecarboxylic Acids | 2008 |
Therapy-resistant opsoclonus-myoclonus syndrome secondary to HIV-1 infection.
Topics: Adult; Amines; Anti-HIV Agents; Anti-Inflammatory Agents; Cyclohexanecarboxylic Acids; Excitatory Am | 2012 |
Epidural lipomatosis causing new debilitating back pain in a patient with human immunodeficiency virus on highly active antiretroviral therapy.
Topics: Adult; Amines; Analgesics; Analgesics, Opioid; Anesthetics, Intravenous; Anti-Inflammatory Agents, N | 2012 |
Two-dimensional 1H MR spectroscopy of the brain in human immunodeficiency virus (HIV)-infected children.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Child; Choline; Creatine; gamma-Aminobutyric Acid; HIV Infe | 2008 |
Science reporters hear wide range of recent data at 12th annual conference.
Topics: Acetates; Aged; AIDS Vaccines; American Medical Association; Amines; Animals; Anticonvulsants; beta- | 1993 |
HIV neuropathy treated with gabapentin.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Aci | 1998 |
Neuropathic pain after anti-HIV gene therapy successfully treated with gabapentin.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Aci | 1999 |
Gabapentin in painful HIV-related neuropathy: a report of 19 patients, preliminary observations.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Ami | 2001 |