gamma-aminobutyric acid has been researched along with Gelineau Syndrome in 16 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Most of the studies evaluating the efficacy of GHB in the treatment of AWS use a dosage of 50 mg/kg divided in three or four administrations per day." | 6.52 | Clinical applications of sodium oxybate (GHB): from narcolepsy to alcohol withdrawal syndrome. ( Busardò, FP; Kyriakou, C; Marinelli, E; Napoletano, S; Zaami, S, 2015) |
| "Histamine was first identified in the brain about 50 years ago, but only in the last few years have researchers gained an understanding of how it regulates sleep/wake behavior." | 2.61 | Histamine: neural circuits and new medications. ( Dauvilliers, Y; Franks, NP; Jackson, AC; Scammell, TE; Wisden, W, 2019) |
| "Histamine has generally excitatory effects on target neurons, but paradoxically, histamine neurons may also release the inhibitory neurotransmitter GABA." | 2.61 | Histamine: neural circuits and new medications. ( Dauvilliers, Y; Franks, NP; Jackson, AC; Scammell, TE; Wisden, W, 2019) |
| " Most of the studies evaluating the efficacy of GHB in the treatment of AWS use a dosage of 50 mg/kg divided in three or four administrations per day." | 2.52 | Clinical applications of sodium oxybate (GHB): from narcolepsy to alcohol withdrawal syndrome. ( Busardò, FP; Kyriakou, C; Marinelli, E; Napoletano, S; Zaami, S, 2015) |
| "Conversely, cataplexy, one of the key symptoms of narcolepsy, is a striking sudden episode of muscle weakness triggered by emotions during wakefulness, and comparable to REM sleep atonia." | 2.47 | The neuronal network responsible for paradoxical sleep and its dysfunctions causing narcolepsy and rapid eye movement (REM) behavior disorder. ( Clément, O; Fort, P; Gervasoni, D; Léger, L; Luppi, PH; Peyron, C; Salvert, D; Sapin, E, 2011) |
| "The pathophysiology of idiopathic hypersomnia (IH) remains unclear." | 1.43 | Absence of γ-aminobutyric acid-a receptor potentiation in central hypersomnolence disorders. ( Barateau, L; Cens, T; Charnet, P; Dauvilliers, Y; Evangelista, E; Jaussent, I; Lopez, R; Rousset, M, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 8 (50.00) | 29.6817 |
| 2010's | 6 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Witt, ST | 1 |
| Drissi, NM | 1 |
| Tapper, S | 1 |
| Wretman, A | 1 |
| Szakács, A | 1 |
| Hallböök, T | 1 |
| Landtblom, AM | 1 |
| Karlsson, T | 1 |
| Lundberg, P | 1 |
| Engström, M | 1 |
| Scammell, TE | 1 |
| Jackson, AC | 1 |
| Franks, NP | 1 |
| Wisden, W | 1 |
| Dauvilliers, Y | 2 |
| Busardò, FP | 1 |
| Kyriakou, C | 1 |
| Napoletano, S | 1 |
| Marinelli, E | 1 |
| Zaami, S | 1 |
| Evangelista, E | 1 |
| Lopez, R | 1 |
| Barateau, L | 1 |
| Jaussent, I | 1 |
| Cens, T | 1 |
| Rousset, M | 1 |
| Charnet, P | 1 |
| Brischoux, F | 1 |
| Mainville, L | 1 |
| Jones, BE | 1 |
| Akins, BE | 1 |
| Miranda, E | 1 |
| Lacy, JM | 1 |
| Logan, BK | 1 |
| Fort, P | 2 |
| Bassetti, CL | 1 |
| Luppi, PH | 2 |
| Mamelak, M | 1 |
| Clément, O | 1 |
| Sapin, E | 1 |
| Gervasoni, D | 1 |
| Peyron, C | 1 |
| Léger, L | 1 |
| Salvert, D | 1 |
| Sinton, CM | 1 |
| Rosin, DL | 1 |
| Weston, MC | 1 |
| Sevigny, CP | 1 |
| Stornetta, RL | 1 |
| Guyenet, PG | 1 |
| Lu, J | 1 |
| Sherman, D | 1 |
| Devor, M | 1 |
| Saper, CB | 1 |
| Kim, SJ | 1 |
| Lyoo, IK | 1 |
| Lee, YS | 1 |
| Sung, YH | 1 |
| Kim, HJ | 1 |
| Kim, JH | 1 |
| Kim, KH | 1 |
| Jeong, DU | 1 |
| Ferraro, L | 1 |
| Antonelli, T | 1 |
| O'Connor, WT | 1 |
| Tanganelli, S | 1 |
| Rambert, FA | 1 |
| Fuxe, K | 1 |
| Siegel, JM | 1 |
| Gerashchenko, D | 1 |
| Salin-Pascual, R | 1 |
| Shiromani, PJ | 1 |
7 reviews available for gamma-aminobutyric acid and Gelineau Syndrome
| Article | Year |
|---|---|
Histamine: neural circuits and new medications.
Topics: Animals; Cataplexy; gamma-Aminobutyric Acid; Histamine; Humans; Hypothalamic Area, Lateral; Narcolep | 2019 |
Clinical applications of sodium oxybate (GHB): from narcolepsy to alcohol withdrawal syndrome.
Topics: Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Female; gamma-Aminobutyric Acid; Humans; I | 2015 |
Alternating vigilance states: new insights regarding neuronal networks and mechanisms.
Topics: Acetylcholine; Animals; Biogenic Monoamines; Brain; gamma-Aminobutyric Acid; Glutamic Acid; Humans; | 2009 |
Narcolepsy and depression and the neurobiology of gammahydroxybutyrate.
Topics: Anesthetics, Intravenous; Animals; Depression; gamma-Aminobutyric Acid; Humans; Intracellular Signal | 2009 |
The neuronal network responsible for paradoxical sleep and its dysfunctions causing narcolepsy and rapid eye movement (REM) behavior disorder.
Topics: Amygdala; Animals; Brain; Brain Mapping; Cataplexy; Emotions; gamma-Aminobutyric Acid; Glutamine; Gl | 2011 |
Orexin/hypocretin plays a role in the response to physiological disequilibrium.
Topics: Adaptation, Physiological; Animals; Arousal; Brain; Cataplexy; Dopamine; Energy Metabolism; gamma-Am | 2011 |
Narcolepsy: a key role for hypocretins (orexins)
Topics: Animals; Appetite; Arousal; Calcium Signaling; Carrier Proteins; Cataplexy; Chromosomes, Human, Pair | 1999 |
9 other studies available for gamma-aminobutyric acid and Gelineau Syndrome
| Article | Year |
|---|---|
Evidence for cognitive resource imbalance in adolescents with narcolepsy.
Topics: Adolescent; Brain; Cognition; Electroencephalography; Female; gamma-Aminobutyric Acid; Glutamic Acid | 2018 |
Absence of γ-aminobutyric acid-a receptor potentiation in central hypersomnolence disorders.
Topics: Adolescent; Adult; Aged; Animals; Case-Control Studies; Disorders of Excessive Somnolence; Female; g | 2016 |
Muscarinic-2 and orexin-2 receptors on GABAergic and other neurons in the rat mesopontine tegmentum and their potential role in sleep-wake state control.
Topics: Acetylcholine; Animals; Biomarkers; Cats; Dogs; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hu | 2008 |
A multi-drug intoxication fatality involving Xyrem (GHB).
Topics: Amines; Benzhydryl Compounds; Carisoprodol; Central Nervous System Depressants; Cetirizine; Cyclohex | 2009 |
Hypothalamic orexin (hypocretin) neurons express vesicular glutamate transporters VGLUT1 or VGLUT2.
Topics: Animals; Appetite Regulation; Carrier Proteins; Efferent Pathways; gamma-Aminobutyric Acid; Glutamat | 2003 |
A putative flip-flop switch for control of REM sleep.
Topics: Animals; Brain; Electroencephalography; gamma-Aminobutyric Acid; Hippocampus; Male; Models, Neurolog | 2006 |
Increased GABA levels in medial prefrontal cortex of young adults with narcolepsy.
Topics: Adult; Basal Ganglia; Cataplexy; Female; gamma-Aminobutyric Acid; Genotype; Glutamic Acid; HLA-DQ An | 2008 |
Modafinil: an antinarcoleptic drug with a different neurochemical profile to d-amphetamine and dopamine uptake blockers.
Topics: Animals; Benzhydryl Compounds; Biogenic Amines; Central Nervous System Stimulants; Dextroamphetamine | 1997 |
Effects of hypocretin-saporin injections into the medial septum on sleep and hippocampal theta.
Topics: Acetylcholine; Animals; Antibodies, Monoclonal; Choline O-Acetyltransferase; Cholinergic Agents; Cho | 2001 |