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gamma-aminobutyric acid and Gastric Ulcer

gamma-aminobutyric acid has been researched along with Gastric Ulcer in 24 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Research Excerpts

ExcerptRelevanceReference
"We investigated the gender difference of selective serotonin reuptake inhibitor, fluoxetine in adult rats with stress-induced gastric ulcer."7.78The gender difference of selective serotonin reuptake inhibitor, fluoxetine in adult rats with stress-induced gastric ulcer. ( Abdel-Daiem, WM; Abdel-Sater, KA; Sayyed Bakheet, M, 2012)
"Effects of systemically administered gamma-aminobutyric acid (GABA) on indomethacin-induced gastric ulceration were studied in rats."7.67Exacerbation of indomethacin-induced gastric ulceration by systemically administered GABA in rats: possible involvement of peripheral GABA receptors. ( Hara, S; Morioka, S; Satoh, K; Yanagihara, S, 1988)
"Fluoxetine was given intraperitoneal in a single dose of 10mg/kg/day."5.38The gender difference of selective serotonin reuptake inhibitor, fluoxetine in adult rats with stress-induced gastric ulcer. ( Abdel-Daiem, WM; Abdel-Sater, KA; Sayyed Bakheet, M, 2012)
"Duodenal ulcers were also observed in about 80% of the hypothermic animals treated with the highest dose of baclofen."5.28[Ulcerogenic effect of a GABA derivative, baclofen, in the rat: effect of hypothermia]. ( Goto, Y; Hara, N; Hara, Y; Natsume, Y, 1990)
"Pretreatment with atropine sulfate antagonized the exacerbating effect of GABA on indomethacin-induced ulceration."5.27Exacerbation of indomethacin-induced gastric ulceration by systemically administered GABA in rats: possible involvement of peripheral GABA receptors. ( Hara, S; Morioka, S; Satoh, K; Yanagihara, S, 1988)
"We investigated the gender difference of selective serotonin reuptake inhibitor, fluoxetine in adult rats with stress-induced gastric ulcer."3.78The gender difference of selective serotonin reuptake inhibitor, fluoxetine in adult rats with stress-induced gastric ulcer. ( Abdel-Daiem, WM; Abdel-Sater, KA; Sayyed Bakheet, M, 2012)
"65 g/100 g per os) reduced the incidence and severity of experimental duodenal ulcer induced by cysteamine HCl, and duodenal ulcer induced by cysteamine-HCl plus GABA."3.68Effects of compound U74500A in animal models of gastric and duodenal ulceration. ( Harding, RK; Krantis, A; McKay, AE; Morris, GP, 1993)
"The occurrence and characteristics of binding sites specific for gamma-aminobutyric acid (GABA) and muscimol in the rat stomach were examined by biochemical and autoradiographic techniques, and the effects of GABAergic model compounds on gastric ulceration induced by chemical irritation was studied in intact and unilaterally vagotomized rats."3.67GABAA receptors in the rat stomach may mediate mucoprotective effects. ( Amenta, F; Erdö, SL; Ezer, E; Matuz, J; Wolff, JR, 1989)
"Effects of systemically administered gamma-aminobutyric acid (GABA) on indomethacin-induced gastric ulceration were studied in rats."3.67Exacerbation of indomethacin-induced gastric ulceration by systemically administered GABA in rats: possible involvement of peripheral GABA receptors. ( Hara, S; Morioka, S; Satoh, K; Yanagihara, S, 1988)
"The effect of exogenous administration of central amino acid neurotransmitters gamma-aminobutyric acid (GABA), glycine, glutamic acid and aspartic acid) into the cerebroventricular system was studied on gastric ulceration induced in albino rats either by 2 h restraint at 4 degrees C or by 6 h restraint at room temperature (30 +/- 2 degrees C)."3.67Central GABA-ergic mechanism in stress-induced gastric ulceration. ( Bhargava, KP; Gupta, GP; Gupta, MB, 1985)
"gamma-Aminobutyric acid (GABA) and sodium valproate (VPA) inhibit the formation of stress-induced gastric ulcers in guinea-pigs."3.67Protective effect of GABA and sodium valproate on stress-induced gastric lesions in guinea-pigs. ( Durán, JA; Miñano, FJ; Sancibrián, M; Serrano, JS, 1985)
"(-)-Myrtenol is a natural fragrance monoterpenoid structurally related to α-pinene found in diverse plant essential oils."1.43Gastroprotective effect of (-)-myrtenol against ethanol-induced acute gastric lesions: possible mechanisms. ( Almeida Santos, F; Braga, MA; da Silva, FV; de Sousa, DP; Fernandes, Hde B; Nunes, PI; Oliveira, IS; Oliveira, Rde C; Rao, VS; Viana, AF; Viana, Dde A, 2016)
"Fluoxetine was given intraperitoneal in a single dose of 10mg/kg/day."1.38The gender difference of selective serotonin reuptake inhibitor, fluoxetine in adult rats with stress-induced gastric ulcer. ( Abdel-Daiem, WM; Abdel-Sater, KA; Sayyed Bakheet, M, 2012)
"Duodenal ulcers were also observed in about 80% of the hypothermic animals treated with the highest dose of baclofen."1.28[Ulcerogenic effect of a GABA derivative, baclofen, in the rat: effect of hypothermia]. ( Goto, Y; Hara, N; Hara, Y; Natsume, Y, 1990)
"Pretreatment with atropine sulfate antagonized the exacerbating effect of GABA on indomethacin-induced ulceration."1.27Exacerbation of indomethacin-induced gastric ulceration by systemically administered GABA in rats: possible involvement of peripheral GABA receptors. ( Hara, S; Morioka, S; Satoh, K; Yanagihara, S, 1988)
"Rats treated with clanobutine had only the one-third of ulcers compared with the untreated animals."1.26[On the influence of clanobutine on the formation of restraint ulcer in rats (author's transl)]. ( Gerlach, U; Hengst, K; Hossdorf, T; Wagner, H, 1979)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199011 (45.83)18.7374
1990's11 (45.83)18.2507
2000's0 (0.00)29.6817
2010's2 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Viana, AF1
da Silva, FV1
Fernandes, Hde B1
Oliveira, IS1
Braga, MA1
Nunes, PI1
Viana, Dde A1
de Sousa, DP1
Rao, VS1
Oliveira, Rde C1
Almeida Santos, F1
Abdel-Sater, KA1
Abdel-Daiem, WM1
Sayyed Bakheet, M1
Mirzoian, SA2
Tatevosian, AT2
Gevorkian, GA1
Sen, S1
Habibuddin, M2
Pal, SP3
Krantis, A1
Harding, RK1
McKay, AE1
Morris, GP1
Goel, RK1
Abbas, WR1
Maiti, RN1
Bhattacharya, SK1
Gianni, AM1
Bruno, G1
Sirtori, C1
Xu, XG1
Zhu, JQ1
Lu, Q1
Wang, X1
Xu, X1
Zhu, J1
Hengst, K1
Hossdorf, T1
Wagner, H1
Gerlach, U1
Sonnenberg, A1
Blum, AL1
Chatterjee, TK1
Chakraborty, A1
Pathak, M1
Sengupta, GC1
Banerji, S1
Hara, N2
Hara, Y2
Natsume, Y2
Goto, Y2
Bhowmick, S1
Bose, R1
Pal, M1
Erdö, SL1
Ezer, E1
Matuz, J1
Wolff, JR1
Amenta, F1
Hara, S1
Yanagihara, S1
Satoh, K1
Morioka, S1
Bhargava, KP1
Gupta, GP1
Gupta, MB1
Miñano, FJ2
Serrano, JS2
Durán, JA1
Sancibrián, M2
Ushijima, I1
Mizuki, Y1
Hara, T1
Kudo, R1
Watanabe, K1
Yamada, M1
Yong, DG1
Geng, BQ1
Gu, GG1
Pascual, J1

Other Studies

24 other studies available for gamma-aminobutyric acid and Gastric Ulcer

ArticleYear
Gastroprotective effect of (-)-myrtenol against ethanol-induced acute gastric lesions: possible mechanisms.
    The Journal of pharmacy and pharmacology, 2016, Volume: 68, Issue:8

    Topics: Animals; Anti-Ulcer Agents; Antioxidants; Bicyclic Monoterpenes; gamma-Aminobutyric Acid; Gastric Mu

2016
The gender difference of selective serotonin reuptake inhibitor, fluoxetine in adult rats with stress-induced gastric ulcer.
    European journal of pharmacology, 2012, Aug-05, Volume: 688, Issue:1-3

    Topics: Animals; Catalase; Cerebral Cortex; Female; Fluoxetine; gamma-Aminobutyric Acid; Gastric Mucosa; Mal

2012
[Effect of gamma-aminobutyric acid and gamma-hydroxybutyric acid on the rate of 14C-leucine incorporation into proteins of the gastric mucosa and hypothalamus].
    Biulleten' eksperimental'noi biologii i meditsiny, 1980, Volume: 90, Issue:9

    Topics: Animals; Anti-Ulcer Agents; gamma-Aminobutyric Acid; Gastric Mucosa; Hydroxybutyrates; Hypothalamus;

1980
Antiulcer and gastric secretory activity of N-octanoyl gamma-aminobutyric acid.
    Life sciences, 1995, Volume: 57, Issue:20

    Topics: Animals; Antacids; Anti-Ulcer Agents; Aspirin; Cold Temperature; Ethanol; gamma-Aminobutyric Acid; G

1995
Effects of compound U74500A in animal models of gastric and duodenal ulceration.
    Digestive diseases and sciences, 1993, Volume: 38, Issue:4

    Topics: Analysis of Variance; Animals; Anti-Ulcer Agents; Cysteamine; Disease Models, Animal; Dose-Response

1993
Anti-ulcerogenic activity of GABA and GABA mimetic agents in rats.
    Indian journal of experimental biology, 1996, Volume: 34, Issue:8

    Topics: Animals; Drug Evaluation, Preclinical; Duodenal Ulcer; Female; GABA Agonists; gamma-Aminobutyric Aci

1996
Effect of pivagabine on stress-induced gastric ulcer formation in rats.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:11A

    Topics: Animals; Cold Temperature; gamma-Aminobutyric Acid; Immobilization; Male; Psychotropic Drugs; Rats;

1997
Exacerbation of cold restraint-induced gastric ulcer by GABA in mice.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1996, Volume: 17, Issue:5

    Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Baclofen; Bicuculline; Cold Temperature; GABA Agoni

1996
[The inhibitory effect of steroids on ethanol induced gastric ulcers and the relation to GABA uptake].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 1997, Volume: 13, Issue:2

    Topics: Animals; Cortisone; Estradiol; Ethanol; Female; gamma-Aminobutyric Acid; Male; Mice; Progesterone; S

1997
[Content of neuroactive amino acids in the hypothalamus and liver of rats in experimental stomach ulcer and their changes under the effect of cholinolytic drugs].
    Zhurnal eksperimental'noi i klinicheskoi meditsiny, 1975, Volume: 15, Issue:5

    Topics: Amino Acids, Diamino; Aminobutyrates; Animals; Diethylamines; gamma-Aminobutyric Acid; Ganglionic Bl

1975
[On the influence of clanobutine on the formation of restraint ulcer in rats (author's transl)].
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:11

    Topics: Animals; Anti-Ulcer Agents; Benzamides; gamma-Aminobutyric Acid; Male; Rats; Restraint, Physical; St

1979
Cell turnover of the gastric mucosa is reduced by clanobutin.
    Acta hepato-gastroenterologica, 1979, Volume: 26, Issue:6

    Topics: Adult; Cell Survival; DNA; Female; gamma-Aminobutyric Acid; Gastric Mucosa; Humans; Male; Stomach Ul

1979
Effects of plant extract Centella asiatica (Linn.) on cold restraint stress ulcer in rats.
    Indian journal of experimental biology, 1992, Volume: 30, Issue:10

    Topics: Animals; Brain; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Male; Plant Extra

1992
Antiulcer and gastric secretory activity of N-phthaloyl gamma-aminobutyric acid.
    European journal of pharmacology, 1992, Aug-25, Volume: 219, Issue:2

    Topics: 3-Mercaptopropionic Acid; Animals; Anti-Ulcer Agents; Aspirin; Bicuculline; Ethanol; gamma-Aminobuty

1992
Gastric hyperacidity and mucosal damage caused by hypothermia correlate with increase in GABA concentrations of the rat brain.
    European journal of pharmacology, 1991, Feb-26, Volume: 194, Issue:1

    Topics: Aminooxyacetic Acid; Anesthesia; Animals; Brain Chemistry; Cold Temperature; gamma-Aminobutyric Acid

1991
Antiulcer activity of N-phthaloyl GABA--a new GABA mimetic agent.
    Indian journal of experimental biology, 1990, Volume: 28, Issue:2

    Topics: 3-Mercaptopropionic Acid; Animals; Anti-Ulcer Agents; Bicuculline; Cimetidine; Dose-Response Relatio

1990
[Ulcerogenic effect of a GABA derivative, baclofen, in the rat: effect of hypothermia].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1990, Volume: 96, Issue:4

    Topics: Animals; Baclofen; Duodenal Ulcer; gamma-Aminobutyric Acid; Gastric Acid; Gastric Mucosa; Hypothermi

1990
GABAA receptors in the rat stomach may mediate mucoprotective effects.
    European journal of pharmacology, 1989, Jun-08, Volume: 165, Issue:1

    Topics: Administration, Oral; Aminooxyacetic Acid; Animals; Anti-Ulcer Agents; Baclofen; Bicuculline; Bindin

1989
Exacerbation of indomethacin-induced gastric ulceration by systemically administered GABA in rats: possible involvement of peripheral GABA receptors.
    Japanese journal of pharmacology, 1988, Volume: 47, Issue:4

    Topics: Animals; Anticonvulsants; Atropine; beta-Alanine; Bicuculline; Drug Synergism; gamma-Aminobutyric Ac

1988
Central GABA-ergic mechanism in stress-induced gastric ulceration.
    British journal of pharmacology, 1985, Volume: 84, Issue:3

    Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Bicuculline; Cold Temperature; Epinephrine; Fema

1985
Protective effect of GABA and sodium valproate on stress-induced gastric lesions in guinea-pigs.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:9

    Topics: Animals; Cold Temperature; Female; gamma-Aminobutyric Acid; Guinea Pigs; Injections, Intraperitoneal

1985
The role of adenosinergic, GABAergic and benzodiazepine systems in hyperemotionality and ulcer formation in stressed rats.
    Psychopharmacology, 1986, Volume: 89, Issue:4

    Topics: Adenosine; Animals; Anti-Anxiety Agents; Benzodiazepines; Brain; Emotions; gamma-Aminobutyric Acid;

1986
[Effects of GABA on gastric ulcers and gastric mucosal barrier in rats].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1985, Volume: 6, Issue:4

    Topics: Animals; DNA; Female; gamma-Aminobutyric Acid; Gastric Acid; Gastric Juice; Gastric Mucosa; Male; Pe

1985
Effects of GABA on gastric acid secretion and ulcer formation in rats.
    Life sciences, 1987, Sep-28, Volume: 41, Issue:13

    Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Gastric Acid; Ligation; Male; Pylorus; Rats

1987