Page last updated: 2024-10-16

gamma-aminobutyric acid and Fatigue Syndrome, Chronic

gamma-aminobutyric acid has been researched along with Fatigue Syndrome, Chronic in 4 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Fatigue Syndrome, Chronic: A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)

Research Excerpts

ExcerptRelevanceReference
"Gamma-aminobutyric acid is a major inhibitory neurotransmitter in the central nervous system."2.44[Gamma-aminobutyric acid--metabolism and its disorders]. ( Kowalski, A; Rebas, E; Zylińska, L, 2007)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kowalski, A1
Rebas, E1
Zylińska, L1
Moore, AR1
Straube, S1
Paine, J1
Phillips, CJ1
Derry, S1
McQuay, HJ1
Murrough, JW1
Mao, X1
Collins, KA1
Kelly, C1
Andrade, G1
Nestadt, P1
Levine, SM1
Mathew, SJ1
Shungu, DC1
Hannestad, U1
Theodorsson, E1
Evengård, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Cannabidiol for Fibromyalgia -The CANNFIB Trial Protocol for a Randomized, Double-blind, Placebo-controlled, Parallel-group, Single-center Trial[NCT04729179]Phase 3200 participants (Anticipated)Interventional2021-03-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for gamma-aminobutyric acid and Fatigue Syndrome, Chronic

ArticleYear
[Gamma-aminobutyric acid--metabolism and its disorders].
    Postepy biochemii, 2007, Volume: 53, Issue:4

    Topics: Anxiety Disorders; Central Nervous System Diseases; Fatigue Syndrome, Chronic; gamma-Aminobutyric Ac

2007

Trials

1 trial available for gamma-aminobutyric acid and Fatigue Syndrome, Chronic

ArticleYear
Fibromyalgia: Moderate and substantial pain intensity reduction predicts improvement in other outcomes and substantial quality of life gain.
    Pain, 2010, Volume: 149, Issue:2

    Topics: Activities of Daily Living; Adult; Analgesics; Fatigue Syndrome, Chronic; Female; Fibromyalgia; gamm

2010

Other Studies

2 other studies available for gamma-aminobutyric acid and Fatigue Syndrome, Chronic

ArticleYear
Increased ventricular lactate in chronic fatigue syndrome measured by 1H MRS imaging at 3.0 T. II: comparison with major depressive disorder.
    NMR in biomedicine, 2010, Volume: 23, Issue:6

    Topics: Adult; Cerebral Ventricles; Depressive Disorder, Major; Fatigue Syndrome, Chronic; Female; gamma-Ami

2010
beta-Alanine and gamma-aminobutyric acid in chronic fatigue syndrome.
    Clinica chimica acta; international journal of clinical chemistry, 2007, Volume: 376, Issue:1-2

    Topics: Adult; beta-Alanine; Fatigue Syndrome, Chronic; Female; gamma-Aminobutyric Acid; Humans; Male; Middl

2007