Page last updated: 2024-10-16

gamma-aminobutyric acid and Fasting Hypoglycemia

gamma-aminobutyric acid has been researched along with Fasting Hypoglycemia in 56 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Fasting Hypoglycemia: HYPOGLYCEMIA expressed in the postabsorptive state, after prolonged FASTING, or an overnight fast.

Research Excerpts

ExcerptRelevanceReference
" Gabapentin was started 1 week prior to the hypoglycemia episode."8.12Patient Case Report: Gabapentin-Induced Hypoglycemia. ( Berendse, J; Ferdinand, A; Hayes, KM; Hayes, WJ; Kappes, JA; Neabore, S, 2022)
"Previous studies have demonstrated that the nitric oxide (NO) synthase inhibitor L-NAME exerts positive effects on the arginine vasopressin (AVP) and oxytocin (OT) responses to insulin-induced hypoglycemia, suggesting inhibitory actions of NO."7.69Gamma-aminobutyric acid mediation of the inhibitory effect of nitric oxide on the arginine vasopressin and oxytocin responses to insulin-induced hypoglycemia. ( Capretti, L; Chiodera, P; Coiro, V; Volpi, R, 1996)
"We have shown that the glucagon irresponsiveness to hypoglycemia in diabetic rats is markedly improved by correction of hyperglycemia independent of insulin."7.69Quantitative measurement of islet glucagon response to hypoglycemia by confocal fluorescence imaging in diabetic rats: effects of phlorizin treatment. ( Cooper, RL; Rastogi, KS; Shi, ZQ; Vranic, M, 1997)
"The present study was carried out in order to determine whether insulin-induced hypoglycemia exerts its stimulatory effect on plasma concentrations of arginine vasopressin (AVP) by interacting with a serotonergic, a GABA-ergic or an opioid pathway."7.67Metergoline, naloxone, and sodium valproate did not modify arginine vasopressin response to insulin-induced hypoglycemia in man. ( Bianconi, L; Castelli, A; Chiodera, P; d'Amato, L; Gnudi, A; Marchesi, C; Minelli, R; Muzzetto, P; Pioli, G; Volpi, R, 1988)
"Gabapentin is an analog of gamma-aminobutyric acid (GABA), but its complete mechanism is not well understood."5.72Patient Case Report: Gabapentin-Induced Hypoglycemia. ( Berendse, J; Ferdinand, A; Hayes, KM; Hayes, WJ; Kappes, JA; Neabore, S, 2022)
"Gabapentin was started 1 week prior to the hypoglycemia episode."5.72Patient Case Report: Gabapentin-Induced Hypoglycemia. ( Berendse, J; Ferdinand, A; Hayes, KM; Hayes, WJ; Kappes, JA; Neabore, S, 2022)
" Gabapentin was started 1 week prior to the hypoglycemia episode."4.12Patient Case Report: Gabapentin-Induced Hypoglycemia. ( Berendse, J; Ferdinand, A; Hayes, KM; Hayes, WJ; Kappes, JA; Neabore, S, 2022)
"We have previously demonstrated that modulation of gamma-aminobutyric acid (GABA) inhibitory tone in the ventromedial hypothalamus (VMH), an important glucose-sensing region in the brain, modulates the magnitude of glucagon and sympathoadrenal responses to hypoglycemia."3.74Increased GABAergic tone in the ventromedial hypothalamus contributes to suppression of counterregulatory responses after antecedent hypoglycemia. ( Chan, O; Cheng, H; Czyzyk, D; Herzog, R; McCrimmon, RJ; Seashore, MR; Sherwin, RS; Wang, A; Zhu, W, 2008)
"Postembedding immunocytochemistry was used to localize aspartate, glutamate, gamma-aminobutyric acid (GABA), and glutamine in hippocampus and striatum during normo- and hypoglycemia in rat."3.71Redistribution of neuroactive amino acids in hippocampus and striatum during hypoglycemia: a quantitative immunogold study. ( Fonnum, F; Gundersen, V; Ottersen, OP; Storm-Mathisen, J, 2001)
"Previous studies have demonstrated that the nitric oxide (NO) synthase inhibitor L-NAME exerts positive effects on the arginine vasopressin (AVP) and oxytocin (OT) responses to insulin-induced hypoglycemia, suggesting inhibitory actions of NO."3.69Gamma-aminobutyric acid mediation of the inhibitory effect of nitric oxide on the arginine vasopressin and oxytocin responses to insulin-induced hypoglycemia. ( Capretti, L; Chiodera, P; Coiro, V; Volpi, R, 1996)
"We have shown that the glucagon irresponsiveness to hypoglycemia in diabetic rats is markedly improved by correction of hyperglycemia independent of insulin."3.69Quantitative measurement of islet glucagon response to hypoglycemia by confocal fluorescence imaging in diabetic rats: effects of phlorizin treatment. ( Cooper, RL; Rastogi, KS; Shi, ZQ; Vranic, M, 1997)
"The present study was carried out in order to determine whether insulin-induced hypoglycemia exerts its stimulatory effect on plasma concentrations of arginine vasopressin (AVP) by interacting with a serotonergic, a GABA-ergic or an opioid pathway."3.67Metergoline, naloxone, and sodium valproate did not modify arginine vasopressin response to insulin-induced hypoglycemia in man. ( Bianconi, L; Castelli, A; Chiodera, P; d'Amato, L; Gnudi, A; Marchesi, C; Minelli, R; Muzzetto, P; Pioli, G; Volpi, R, 1988)
" One to two weeks later the effects of insulin-induced hypoglycemia on the steady-state levels of amino acids [Glu, glutamine (Gln), aspartate (Asp), gamma-aminobutyric acid (GABA), taurine] and energy metabolites (glucose, glycogen, alpha-ketoglutarate, pyruvate, lactate, ATP, ADP, AMP, phosphocreatine) were examined in the intact and decorticated neostriatum from brains frozen in situ."3.67Effect of insulin-induced hypoglycemia on the concentrations of glutamate and related amino acids and energy metabolites in the intact and decorticated rat neostriatum. ( Engelsen, B; Fonnum, F; Westerberg, E; Wieloch, T, 1986)
"Extracellular levels of striatal gamma-aminobutyric acid (GABA) and taurine were monitored during insulin-induced hypoglycemia using microdialysis."3.67gamma-Aminobutyric acid and taurine release in the striatum of the rat during hypoglycemic coma, studied by microdialysis. ( Tossman, U; Ungerstedt, U; Wieloch, T, 1985)
"Gabapentin is an analog of gamma-aminobutyric acid (GABA), but its complete mechanism is not well understood."1.72Patient Case Report: Gabapentin-Induced Hypoglycemia. ( Berendse, J; Ferdinand, A; Hayes, KM; Hayes, WJ; Kappes, JA; Neabore, S, 2022)
"Gabapentin was started 1 week prior to the hypoglycemia episode."1.72Patient Case Report: Gabapentin-Induced Hypoglycemia. ( Berendse, J; Ferdinand, A; Hayes, KM; Hayes, WJ; Kappes, JA; Neabore, S, 2022)
"Onset of symptoms (severe catalepsy and loss of righting reflex, but before the onset of convulsions) was accompanied by marked decreases of glutamate and glutamine in striatum and hippocampus."1.26Regional amino acid distribution in relation to function in insulin hypoglycaemia. ( Butterworth, RF; Landreville, F; Merkel, AD, 1982)

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199017 (30.36)18.7374
1990's11 (19.64)18.2507
2000's13 (23.21)29.6817
2010's10 (17.86)24.3611
2020's5 (8.93)2.80

Authors

AuthorsStudies
Espes, D1
Liljebäck, H1
Hill, H1
Elksnis, A1
Caballero-Corbalan, J1
Carlsson, PO1
Zhou, H1
Rao, Z1
Zhang, Z1
Zhou, J1
Taneda, T1
Okawara, S1
Namekawa, M1
Umeda, Y1
Oyake, M1
Fujita, N1
Mahmood, ASMH1
Roy, SC1
Leprince, J1
Briski, KP1
Hayes, WJ1
Ferdinand, A1
Neabore, S1
Kappes, JA1
Hayes, KM1
Berendse, J1
Shah, M1
Addison, A1
Wang, P1
Zhu, W6
Chan, O6
Moheet, A1
Emir, UE1
Terpstra, M1
Kumar, A1
Eberly, LE1
Seaquist, ER1
Öz, G1
Koska, P1
Dojcsák Kiss-Tóth, E1
Juhász Szalai, A1
Kovács, GL1
Barkai, L1
Rácz, O1
Fodor, B1
Paranjape, SA2
Horblitt, A3
Sherwin, RS5
Arbeláez, AM1
Cryer, PE1
Klement, J1
Mergelkuhl, B1
Born, J1
Lehnert, H1
Hallschmid, M1
Scholl, JH1
van Eekeren, R1
van Puijenbroek, EP1
Al-Noori, S1
Sanders, NM1
Taborsky, GJ1
Wilkinson, CW1
Zavosh, A1
West, C1
Sanders, CM1
Figlewicz, DP1
Czyzyk, D3
Zhou, L1
Szabó, G1
Seashore, MR2
Sherin, A1
Peeyush, KT1
Naijil, G1
Chinthu, R1
Paulose, CS1
Paranjape, S1
Ding, Y1
Fan, X1
Seashore, M1
Sherwin, R1
Gorell, JM1
Dolkart, PH1
Ferrendelli, JA1
Aihara, H1
Fujiwara, S1
Mizuta, I1
Tada, H1
Kanno, T1
Tozaki, H1
Nagai, K1
Yajima, Y1
Inoue, K1
Kondoh, T1
Motooka, Y1
Nishizaki, T1
HAULICA, I1
CAPALNA, S1
NESTIANU, V1
BORDEIANU, A1
BADESCU, A1
Penumalee, S1
Kissner, PZ1
Migdal, SD1
Zhang, M1
Buttigieg, J1
Nurse, CA1
Lawson, M1
Beverly, JL2
Velísková, J1
Chudomel, O1
Poon, KL1
Marshall, B1
Velísek, L1
Cheng, H1
Herzog, R1
Wang, A1
McCrimmon, RJ1
Butterworth, RF1
Merkel, AD1
Landreville, F1
Benzi, G1
Villa, RF1
Dossena, M1
Vercesi, L1
Gorini, A1
Pastoris, O1
Shuaib, A1
Ijaz, MS1
Waqar, T1
Voll, C1
Kanthan, R1
Miyashita, H1
Liu, L1
During, MJ1
Leone, P1
Davis, KE1
Kerr, D1
McCarty, MF1
Boireau, A1
Meunier, M1
Doble, A1
Saransaari, P2
Oja, SS2
Chiodera, P2
Volpi, R2
Capretti, L1
Coiro, V1
Rastogi, KS1
Cooper, RL1
Shi, ZQ1
Vranic, M1
Madl, JE1
Royer, SM1
Guyot, LL1
Diaz, FG1
O'Regan, MH1
Ren, J1
Phillis, JW1
Gundersen, V1
Fonnum, F4
Ottersen, OP1
Storm-Mathisen, J1
De Vries, MG1
Bouman, SD1
Arseneau, LM1
Sonnewald, U1
McKenna, M1
Kalloniatis, M1
Napper, GA1
Semiginovský, B1
Sobotka, P1
Jakoubek, B1
Bluet-Pajot, MT1
Schaub, C1
Nassiet, J1
Buczek, M1
Harrington, JF1
Lust, WD1
Assaf, HM1
Ratcheson, RA1
Erecińska, M1
Silver, IA1
Rogers, H1
Birch, PJ1
Hayes, AG1
Ohsuga, S1
Ohsuga, H1
Takeoka, T1
Ikeda, A1
Shinohara, Y1
Itagaki, T1
Hishimura, M1
Hatta, M1
Takenaka, H1
Yoshida, R1
Yasuhara, O1
Urushibara, A1
Gnudi, A1
d'Amato, L1
Marchesi, C1
Pioli, G1
Muzzetto, P1
Castelli, A1
Bianconi, L1
Minelli, R1
Wieloch, T3
Engelsen, B2
Westerberg, E1
Butcher, SP1
Sandberg, M1
Hagberg, H1
Hamberger, A1
Paulsen, RE1
Paulsen, RH1
Fosse, VM1
Johnson, R1
Tossman, U1
Ungerstedt, U1
Lewis, LD1
Ljunggren, B1
Norberg, K1
Siesjö, BK1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase I/II, 3-Arm, Open Label, Single Centre Study to Investigate the Safety and Effect of Oral GABA Therapy on Beta-Cell Regeneration in Type 1-diabetes Patients[NCT03635437]Phase 1/Phase 235 participants (Actual)Interventional2018-09-05Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for gamma-aminobutyric acid and Fasting Hypoglycemia

ArticleYear
Function of the GABAergic System in Diabetic Encephalopathy.
    Cellular and molecular neurobiology, 2023, Volume: 43, Issue:2

    Topics: Adult; Animals; Blood Glucose; Brain Diseases; Diabetes Mellitus; gamma-Aminobutyric Acid; Humans; H

2023
Brain glucose sensing and counterregulatory response to hypoglycaemia.
    Acta physiologica Hungarica, 2013, Volume: 100, Issue:2

    Topics: Animals; Autonomic Pathways; Blood Glucose; gamma-Aminobutyric Acid; Homeostasis; Humans; Hypoglycem

2013
Metabolism and role of glutamate in mammalian brain.
    Progress in neurobiology, 1990, Volume: 35, Issue:4

    Topics: Animals; Astrocytes; Biological Transport; Brain; Brain Chemistry; gamma-Aminobutyric Acid; Glucose;

1990
Neurochemical correlates to selective neuronal vulnerability.
    Progress in brain research, 1985, Volume: 63

    Topics: Adenosine; Afferent Pathways; Animals; Aspartic Acid; Brain Diseases; Brain Ischemia; Calcium; Chlor

1985
Alcohol and fits.
    British journal of addiction, 1985, Volume: 80, Issue:3

    Topics: Adolescent; Adult; Aged; Alcoholic Intoxication; Alcoholism; Anticonvulsants; Brain Chemistry; Brain

1985

Trials

1 trial available for gamma-aminobutyric acid and Fasting Hypoglycemia

ArticleYear
GABA induces a hormonal counter-regulatory response in subjects with long-standing type 1 diabetes.
    BMJ open diabetes research & care, 2021, Volume: 9, Issue:1

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; gamma-Aminobutyric Acid; Humans; Hypoglycemia; Insu

2021

Other Studies

50 other studies available for gamma-aminobutyric acid and Fasting Hypoglycemia

ArticleYear
[Isolated ACTH deficiency clinically presented as stiff-person syndrome, successfully treated by hormonal replacement: a case report].
    Rinsho shinkeigaku = Clinical neurology, 2022, Sep-28, Volume: 62, Issue:9

    Topics: Adrenocorticotropic Hormone; Aged; Aminobutyrates; Autoantibodies; Contracture; Endocrine System Dis

2022
Sex-dependent endozepinergic regulation of ventromedial hypothalamic nucleus glucose counter-regulatory neuron aromatase protein expression in the adult rat.
    Journal of chemical neuroanatomy, 2023, Volume: 132

    Topics: Animals; Aromatase; Estradiol; Female; gamma-Aminobutyric Acid; Glucose; Glycogen; Hypoglycemia; Hyp

2023
Patient Case Report: Gabapentin-Induced Hypoglycemia.
    Journal of pharmacy practice, 2022, Volume: 35, Issue:2

    Topics: Amines; Calcium Channels; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid;

2022
Recurrent glucose deprivation leads to the preferential use of lactate by neurons in the ventromedial hypothalamus.
    American journal of physiology. Endocrinology and metabolism, 2019, 05-01, Volume: 316, Issue:5

    Topics: Animals; Carbon Radioisotopes; Catecholamines; Coumaric Acids; gamma-Aminobutyric Acid; Glucose; Glu

2019
Initial experience with seven tesla magnetic resonance spectroscopy of hypothalamic GABA during hyperinsulinemic euglycemia and hypoglycemia in healthy humans.
    Magnetic resonance in medicine, 2014, Volume: 71, Issue:1

    Topics: Adult; Blood Glucose; Female; gamma-Aminobutyric Acid; Humans; Hyperinsulinism; Hypoglycemia; Hypoth

2014
Lactate-induced release of GABA in the ventromedial hypothalamus contributes to counterregulatory failure in recurrent hypoglycemia and diabetes.
    Diabetes, 2013, Volume: 62, Issue:12

    Topics: Animals; Bicuculline; Coumaric Acids; Diabetes Mellitus, Experimental; Diazoxide; GABA Antagonists;

2013
Lactate and the mechanism of hypoglycemia-associated autonomic failure in diabetes.
    Diabetes, 2013, Volume: 62, Issue:12

    Topics: Animals; Diabetes Mellitus, Experimental; gamma-Aminobutyric Acid; Hypoglycemia; Lactic Acid; Male;

2013
Role of γ-aminobutyric acid signalling in the attenuation of counter-regulatory hormonal responses after antecedent hypoglycaemia in healthy men.
    Diabetes, obesity & metabolism, 2014, Volume: 16, Issue:12

    Topics: Adrenocorticotropic Hormone; Adult; Analysis of Variance; Benzhydryl Compounds; Blood Glucose; Cytoc

2014
Six cases of (severe) hypoglycaemia associated with gabapentin use in both diabetic and non-diabetic patients.
    British journal of clinical pharmacology, 2015, Volume: 79, Issue:5

    Topics: Amines; Analgesics; Blood Glucose; Cyclohexanecarboxylic Acids; Diabetes Mellitus; Gabapentin; gamma

2015
Recurrent hypoglycemia alters hypothalamic expression of the regulatory proteins FosB and synaptophysin.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 295, Issue:5

    Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Blotting, Western; Epinephrine; Fluorescent Ant

2008
Glucose prevents the fall in ventromedial hypothalamic GABA that is required for full activation of glucose counterregulatory responses during hypoglycemia.
    American journal of physiology. Endocrinology and metabolism, 2010, Volume: 298, Issue:5

    Topics: Analysis of Variance; Animals; Bicuculline; Blood Glucose; Catheters, Indwelling; Diazoxide; Epineph

2010
Hypoglycemia induced behavioural deficit and decreased GABA receptor, CREB expression in the cerebellum of streptozoticin induced diabetic rats.
    Brain research bulletin, 2010, Nov-20, Volume: 83, Issue:6

    Topics: Analysis of Variance; Animals; Cerebellum; CREB-Binding Protein; Diabetes Mellitus, Experimental; Di

2010
Increased GABAergic output in the ventromedial hypothalamus contributes to impaired hypoglycemic counterregulation in diabetic rats.
    Diabetes, 2011, Volume: 60, Issue:5

    Topics: Animals; Diabetes Mellitus, Experimental; gamma-Aminobutyric Acid; Glucose Clamp Technique; Glutamat

2011
Regional levels of glucose, amino acids, high energy phosphates, and cyclic nucleotides in the central nervous system during hypoglycemic stupor and behavioral recovery.
    Journal of neurochemistry, 1976, Volume: 27, Issue:5

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Animals; Aspartic Acid; Behavior, Anim

1976
Adenosine triphosphate accelerates recovery from hypoxic/hypoglycemic perturbation of guinea pig hippocampal neurotransmission via a P(2) receptor.
    Brain research, 2002, Oct-11, Volume: 952, Issue:1

    Topics: Adenosine Triphosphate; Animals; Astrocytes; Cells, Cultured; Dose-Response Relationship, Drug; gamm

2002
CONTRIBUTIONS TO THE STUDY OF GAMMA-AMINOBUTYRIC ACID (GABA) IN THE HYPOTHALAMO-HYPOPHYSEAL PATHWAYS.
    International journal of neuropharmacology, 1964, Volume: 3

    Topics: Aminobutyrates; Chlorpromazine; Dogs; Electroencephalography; gamma-Aminobutyric Acid; Histocytochem

1964
Gabapentin-induced hypoglycemia in a long-term peritoneal dialysis patient.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 42, Issue:6

    Topics: Acetates; Amines; C-Peptide; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Aci

2003
Neurotransmitter mechanisms mediating low-glucose signalling in cocultures and fresh tissue slices of rat carotid body.
    The Journal of physiology, 2007, Feb-01, Volume: 578, Issue:Pt 3

    Topics: Acetylcholine; Action Potentials; Adenosine Triphosphate; Animals; Blood Glucose; Carotid Body; Cocu

2007
ATP-sensitive K(+) channels regulate the release of GABA in the ventromedial hypothalamus during hypoglycemia.
    Diabetes, 2007, Volume: 56, Issue:4

    Topics: Animals; Blood Glucose; Diazoxide; Epinephrine; gamma-Aminobutyric Acid; Glucagon; Glucose Clamp Tec

2007
The involvement of the substantia nigra pars reticulata in hypoglycemic seizures.
    Epilepsia, 2007, Volume: 48 Suppl 5

    Topics: Animals; Baclofen; Behavior, Animal; Disease Models, Animal; Fasting; GABA-A Receptor Agonists; gamm

2007
Increased GABAergic tone in the ventromedial hypothalamus contributes to suppression of counterregulatory responses after antecedent hypoglycemia.
    Diabetes, 2008, Volume: 57, Issue:5

    Topics: Animals; Disease Models, Animal; DNA Primers; gamma-Aminobutyric Acid; Gene Expression Regulation, E

2008
Regional amino acid distribution in relation to function in insulin hypoglycaemia.
    Journal of neurochemistry, 1982, Volume: 38, Issue:5

    Topics: Amino Acids; Animals; Aspartic Acid; Brain; Catalepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic

1982
Cerebral endogenous substrate utilization during the recovery period after profound hypoglycemia.
    Journal of neuroscience research, 1984, Volume: 11, Issue:4

    Topics: 6-Aminonicotinamide; Acetylcarnitine; Animals; Cerebral Cortex; Energy Metabolism; gamma-Aminobutyri

1984
Insulin elevates hippocampal GABA levels during ischemia. This is independent of its hypoglycemic effect.
    Neuroscience, 1995, Volume: 67, Issue:4

    Topics: Animals; Brain Ischemia; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Gerbillinae;

1995
Glucose modulates rat substantia nigra GABA release in vivo via ATP-sensitive potassium channels.
    The Journal of clinical investigation, 1995, Volume: 95, Issue:5

    Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Deoxyglucose; gamma-Aminobutyric Acid; Glipiz

1995
Chromium and other insulin sensitizers may enhance glucagon secretion: implications for hypoglycemia and weight control.
    Medical hypotheses, 1996, Volume: 46, Issue:2

    Topics: Chromium; Down-Regulation; gamma-Aminobutyric Acid; Glucagon; Humans; Hypoglycemia; Insulin; Insulin

1996
3-Nitropropionic acid exacerbates [3H]GABA release evoked by glucose deprivation in rat striatal slices.
    The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:1

    Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Ac

1996
GABA release is enhanced in mouse hippocampal slices in cell-damaging conditions.
    Proceedings of the Western Pharmacology Society, 1996, Volume: 39

    Topics: 2,4-Dinitrophenol; Animals; Brain Ischemia; Female; Free Radicals; gamma-Aminobutyric Acid; Hippocam

1996
Gamma-aminobutyric acid mediation of the inhibitory effect of nitric oxide on the arginine vasopressin and oxytocin responses to insulin-induced hypoglycemia.
    Regulatory peptides, 1996, Nov-14, Volume: 67, Issue:1

    Topics: Adult; Arginine Vasopressin; Blood Glucose; Enzyme Inhibitors; GABA Agents; gamma-Aminobutyric Acid;

1996
Enhanced GABA release in cell-damaging conditions in the adult and developing mouse hippocampus.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1997, Volume: 15, Issue:2

    Topics: Animals; Animals, Newborn; Brain Diseases; Brain Ischemia; Calcium; Culture Media; Female; Free Radi

1997
Quantitative measurement of islet glucagon response to hypoglycemia by confocal fluorescence imaging in diabetic rats: effects of phlorizin treatment.
    Endocrine, 1997, Volume: 7, Issue:3

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Fluorescent Antibody Technique, Direct; gam

1997
Glutamate dependence of GABA levels in neurons of hypoxic and hypoglycemic rat hippocampal slices.
    Neuroscience, 2000, Volume: 96, Issue:4

    Topics: 4-Aminobutyrate Transaminase; Adenosine Triphosphate; Animals; gamma-Aminobutyric Acid; Glucose; Glu

2000
The effect of intravenous insulin on accumulation of excitotoxic and other amino acids in the ischemic rat cerebral cortex.
    Neuroscience letters, 2000, Jul-07, Volume: 288, Issue:1

    Topics: Animals; Aspartic Acid; Brain Chemistry; Cerebral Cortex; Energy Metabolism; gamma-Aminobutyric Acid

2000
Redistribution of neuroactive amino acids in hippocampus and striatum during hypoglycemia: a quantitative immunogold study.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2001, Volume: 21, Issue:1

    Topics: Amino Acids; Animals; Aspartic Acid; Corpus Striatum; gamma-Aminobutyric Acid; Glutamic Acid; Glutam

2001
Noradrenergic and GABAergic systems in the medial hypothalamus are activated during hypoglycemia.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 280, Issue:2

    Topics: Animals; Blood Glucose; gamma-Aminobutyric Acid; Glucose Clamp Technique; Hypoglycemia; Hypothalamus

2001
Metabolic compartmentation in cortical synaptosomes: influence of glucose and preferential incorporation of endogenous glutamate into GABA.
    Neurochemical research, 2002, Volume: 27, Issue:1-2

    Topics: Animals; Aspartic Acid; Cerebral Cortex; Citric Acid Cycle; Drug Synergism; gamma-Aminobutyric Acid;

2002
Retinal neurochemical changes following application of glutamate as a metablolic substrate.
    Clinical & experimental optometry, 2002, Volume: 85, Issue:1

    Topics: Animals; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Hypoglycemia; Immunohistochemistry; Neurog

2002
A contribution to the neurochemical basis of the pyrithioxin effect on the brain glucose utilisation during relative brain hypoglycaemia induced by anticipation stress.
    Activitas nervosa superior, 1978, Volume: 20, Issue:1

    Topics: Alanine; Ammonia; Animals; Blood Glucose; Brain; Ethanolamines; gamma-Aminobutyric Acid; Humans; Hyp

1978
Growth hormone response to hypoglycemia under gamma-hydroxybutyrate narco-analgesia in the rat.
    Neuroendocrinology, 1978, Volume: 26, Issue:3

    Topics: Aminobutyrates; Animals; gamma-Aminobutyric Acid; Growth Hormone; Hypoglycemia; Insulin; Male; Perio

1978
[Effect of metabolic stress on the release of glutamic acid and GABA in the brain tissue of Mongolian hamsters].
    Neurologia i neurochirurgia polska, 1992, Volume: Suppl 1

    Topics: Animals; Cricetinae; Disease Models, Animal; Extracellular Space; Female; gamma-Aminobutyric Acid; G

1992
Effects of hypoxia and hypoglycaemia on DC potentials recorded from the gerbil hippocampus in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 342, Issue:5

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Ischemia; Cell Hypoxia; gam

1990
[Metabolic acidosis and hypoglycemia during calcium hopantenate administration--report on 5 patients].
    Rinsho shinkeigaku = Clinical neurology, 1989, Volume: 29, Issue:6

    Topics: Acidosis, Lactic; Aged; Aged, 80 and over; Female; gamma-Aminobutyric Acid; Humans; Hypoglycemia; Ma

1989
[The relationship between the physical features and medications in Reye-like syndrome in elderly patients].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1989, Volume: 26, Issue:6

    Topics: Aged; Aged, 80 and over; Brain; Female; gamma-Aminobutyric Acid; Humans; Hypoglycemia; Male; Pantoth

1989
Metergoline, naloxone, and sodium valproate did not modify arginine vasopressin response to insulin-induced hypoglycemia in man.
    Journal of endocrinological investigation, 1988, Volume: 11, Issue:5

    Topics: Adrenocorticotropic Hormone; Adult; Arginine Vasopressin; Ergolines; gamma-Aminobutyric Acid; Growth

1988
Effect of insulin-induced hypoglycemia on the concentrations of glutamate and related amino acids and energy metabolites in the intact and decorticated rat neostriatum.
    Journal of neurochemistry, 1986, Volume: 47, Issue:5

    Topics: Amino Acids; Animals; Cerebral Cortex; Electroencephalography; Energy Metabolism; gamma-Aminobutyric

1986
Cellular origins of endogenous amino acids released into the extracellular fluid of the rat striatum during severe insulin-induced hypoglycemia.
    Journal of neurochemistry, 1987, Volume: 48, Issue:3

    Topics: Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Corpus Striatum; Denervation; Ethanolamines; E

1987
Regulation of transmitter gamma-aminobutyric acid (GABA) synthesis and metabolism illustrated by the effect of gamma-vinyl GABA and hypoglycemia.
    Journal of neurochemistry, 1988, Volume: 50, Issue:4

    Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Animals; Aspartic Acid; Corpus Striatum; gamma-Aminobu

1988
Synthesis and release of amino acid transmitters.
    Advances in experimental medicine and biology, 1986, Volume: 203

    Topics: Animals; Aspartic Acid; Brain; Citrates; Corpus Striatum; gamma-Aminobutyric Acid; Glutamates; Hypog

1986
gamma-Aminobutyric acid and taurine release in the striatum of the rat during hypoglycemic coma, studied by microdialysis.
    Neuroscience letters, 1985, Dec-04, Volume: 62, Issue:2

    Topics: Animals; Corpus Striatum; Dialysis; Electroencephalography; gamma-Aminobutyric Acid; Hypoglycemia; I

1985
Changes in carbohydrate substrates, amino acids and ammonia in the brain during insulin-induced hypoglycemia.
    Journal of neurochemistry, 1974, Volume: 23, Issue:4

    Topics: Alanine; Amino Acids; Ammonia; Animals; Blood Glucose; Carbohydrate Metabolism; Cerebral Cortex; Cit

1974