gamma-aminobutyric acid has been researched along with Epilepsy, Absence in 110 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Epilepsy, Absence: A seizure disorder usually occurring in childhood characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vigabatrin is a specific and irreversible inhibitor of the enzyme gamma-amino-butyric-acid (GABA) transferase." | 6.39 | [Vigabatrin and lamotrigin: experiences with 2 new anticonvulsants in the Swiss epilepsy clinic]. ( Krämer, G; Vogt, H, 1995) |
| "Absence epilepsy is classified as a childhood generalized epilepsy syndrome with distinctive electroencephalographic patterns." | 5.62 | Vasoactive intestinal peptide (VIP) conducts the neuronal activity during absence seizures: GABA seems to be the main mediator of VIP. ( Arkan, S; Ateş, N; Korkmaz, OT; Öncü-Kaya, EM; Tunçel, N, 2021) |
| "Absence seizures (ASs) are associated with abnormalities in gamma-aminobutyric acid (GABA) neurotransmission in the thalamus and the cortex." | 3.88 | Developmental changes of GABA immunoreactivity in cortico-thalamic networks of an absence seizure model. ( Bombardi, C; Crunelli, V; Di Giovanni, G; Venzi, M, 2018) |
| "The effect of the combined administration of gamma-aminobutyric acid (GABA) and phosphatidylserine was evaluated in a pilot study of 42 patients with drug-resistant epilepsy." | 3.67 | Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients. ( Benassi, E; Bo, GP; Cocito, L; Loeb, C; Maffini, M; Scotto, P, 1987) |
| "The lumbar cerebrospinal fluid (CSF) gamma-aminobutyric acid (GABA) levels were measured in 27 patients with epilepsy, another three epileptic patients with status epilepticus and three epileptic patients with chronic cerebellar ataxia." | 3.67 | GABA levels in cerebrospinal fluid of patients with epilepsy. ( Hosokawa, K; Kugoh, T; Ogawa, N; Otsuki, S; Takahashi, S; Yamamoto, M, 1985) |
| "Childhood absence epilepsy and juvenile absence epilepsy are among the most common subtypes of IAEs." | 2.48 | Genes and molecular mechanisms involved in the epileptogenesis of idiopathic absence epilepsies. ( Yalçın, O, 2012) |
| "Murine models of inborn errors of metabolism represent an established approach for investigating pathophysiological mechanisms associated with the corresponding human disorder." | 2.43 | Murine succinate semialdehyde dehydrogenase (SSADH) deficiency, a heritable disorder of GABA metabolism with epileptic phenotype. ( Gibson, KM; Jakobs, C; Pearl, PL; Snead, OC, 2005) |
| "Vigabatrin is a specific and irreversible inhibitor of the enzyme gamma-amino-butyric-acid (GABA) transferase." | 2.39 | [Vigabatrin and lamotrigin: experiences with 2 new anticonvulsants in the Swiss epilepsy clinic]. ( Krämer, G; Vogt, H, 1995) |
| "Valproic acid is a new antiepileptic drug." | 2.36 | Valproic acid. Review of a new antiepileptic drug. ( Bruni, J; Wilder, BJ, 1979) |
| "Childhood absence epilepsy seizures arise in the cortico-thalamocortical network due to multiple cellular and molecular mechanisms, which are still under investigation." | 1.91 | Developmental Inhibitory Changes in the Primary Somatosensory Cortex of the Stargazer Mouse Model of Absence Epilepsy. ( Grattan, DR; Hassan, M; Leitch, B, 2023) |
| "Absence seizures are hyperexcitations within the cortico-thalamocortical (CTC) network, however the underlying causative mechanisms at the cellular and molecular level are still being elucidated and appear to be multifactorial." | 1.72 | Altered GABA ( Adotevi, NK; Hassan, M; Leitch, B, 2022) |
| "Absence epilepsy is classified as a childhood generalized epilepsy syndrome with distinctive electroencephalographic patterns." | 1.62 | Vasoactive intestinal peptide (VIP) conducts the neuronal activity during absence seizures: GABA seems to be the main mediator of VIP. ( Arkan, S; Ateş, N; Korkmaz, OT; Öncü-Kaya, EM; Tunçel, N, 2021) |
| "Absence seizures are associated with generalised synchronous 2." | 1.62 | Impact of Dysfunctional Feed-Forward Inhibition on Glutamate Decarboxylase Isoforms and γ-Aminobutyric Acid Transporters. ( Leitch, B; Lyons, NMA; Panthi, S, 2021) |
| "We performed EEG recordings and autism diagnostic interview." | 1.56 | Endoplasmic reticulum retention and degradation of a mutation in SLC6A1 associated with epilepsy and autism. ( Cai, K; Delpire, E; Eissman, J; Flamm, C; Kang, JQ; Li, BM; Li, ZY; Liao, WP; Mermer, F; Nwosu, G; Poliquin, S; Shen, W; Shi, YW; Wang, J; Xu, D, 2020) |
| "Absence seizures (ASs) are associated with abnormalities in gamma-aminobutyric acid (GABA) neurotransmission in the thalamus and the cortex." | 1.48 | Developmental changes of GABA immunoreactivity in cortico-thalamic networks of an absence seizure model. ( Bombardi, C; Crunelli, V; Di Giovanni, G; Venzi, M, 2018) |
| "In these models epileptic seizures are triggered either by external stimuli (reflex epilepsies) or by internal fluctuations." | 1.37 | Plasticity-modulated seizure dynamics for seizure termination in realistic neuronal models. ( Kalitzin, S; Koppert, MM; Lopes da Silva, FH; Viergever, MA, 2011) |
| "Vigabatrin was used with the aim of enhancing GABAergic neurotransmission, and in this way to investigate the role of this process in the properties of SWDs." | 1.34 | GABAergic mechanisms in absence epilepsy: a computational model of absence epilepsy simulating spike and wave discharges after vigabatrin in WAG/Rij rats. ( Bouwman, BM; Lopes da Silva, FH; Maris, E; Suffczynski, P; van Rijn, CM, 2007) |
| "(a) The minimal substrate of SW seizures is the neocortex because such seizures may occur in thalamectomized animals, in which spindles are absent." | 1.32 | Sleep oscillations developing into seizures in corticothalamic systems. ( Amzica, F; Steriade, M, 2003) |
| "GABA is crucial in the generation of absence seizures." | 1.31 | Selective susceptibility to inhibitors of GABA synthesis and antagonists of GABA(A) receptor in rats with genetic absence epilepsy. ( Boehrer, A; Marescaux, C; Reibel, S; Simler, S; Vergnes, M, 2000) |
| "Vigabatrin was also used in the treatment of two children." | 1.30 | Inappropriate use of carbamazepine and vigabatrin in typical absence seizures. ( Agathonikou, A; Panayiotopoulos, CP; Parker, AP; Robinson, RO, 1998) |
| " Neither bicuculline nor GABA altered the dose-response of steroids in the [3H]GHB assay, suggesting that there was no GABAA component involved in the steroid-inhibition of [3H]GHB binding." | 1.30 | Steroid-inhibition of [3H]gamma-hydroxybutyric acid (GHB) binding in thalamic relay nuclei increases during absence seizures. ( Banerjee, PK; Liu, CC; Snead, OC, 1998) |
| "In conclusion, the results confirm a genetic susceptibility in GAERS and/or resistance in inbred non-epileptic rats to focal and generalized seizures involving the cortex." | 1.30 | Susceptibility to focal and generalized seizures in Wistar rats with genetic absence-like epilepsy. ( Boehrer, A; Brailowsky, S; Marescaux, C; Montiel, T; Vergnes, M, 1999) |
| "Paradoxically, GABA agonists increased seizure occurrence while GABA antagonists decreased seizure occurrence." | 1.28 | Paradoxical role of GABA in a chronic model of petit mal (absence)-like epilepsy in the rat. ( Bierkamper, GG; Smith, KA, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (9.09) | 18.7374 |
| 1990's | 33 (30.00) | 18.2507 |
| 2000's | 43 (39.09) | 29.6817 |
| 2010's | 14 (12.73) | 24.3611 |
| 2020's | 10 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Korkmaz, OT | 1 |
| Arkan, S | 1 |
| Öncü-Kaya, EM | 1 |
| Ateş, N | 1 |
| Tunçel, N | 1 |
| Mermer, F | 2 |
| Poliquin, S | 2 |
| Zhou, S | 1 |
| Wang, X | 2 |
| Ding, Y | 1 |
| Yin, F | 1 |
| Shen, W | 2 |
| Wang, J | 3 |
| Rigsby, K | 1 |
| Xu, D | 2 |
| Mack, T | 1 |
| Nwosu, G | 2 |
| Flamm, C | 2 |
| Stein, M | 1 |
| Kang, JQ | 2 |
| Hassan, M | 2 |
| Adotevi, NK | 1 |
| Leitch, B | 3 |
| Grattan, DR | 1 |
| Eissman, J | 1 |
| Delpire, E | 1 |
| Cai, K | 1 |
| Li, BM | 1 |
| Li, ZY | 1 |
| Liao, WP | 1 |
| Shi, YW | 1 |
| Sirvanci, S | 7 |
| Akakin, D | 4 |
| Gulcebi İdrizoglu, M | 1 |
| Kaya, OT | 1 |
| Karamahmutoglu, T | 1 |
| Turgan Aşık, ZN | 1 |
| Onat, F | 9 |
| Myers, KA | 1 |
| Bennett, MF | 1 |
| Grinton, BE | 1 |
| Dabscheck, G | 1 |
| Chan, EK | 1 |
| Bello-Espinosa, LE | 1 |
| Sadleir, LG | 1 |
| D'Alfonso, S | 1 |
| Schneider, AL | 1 |
| Damiano, JA | 1 |
| Hildebrand, MS | 1 |
| Bahlo, M | 1 |
| Berkovic, SF | 1 |
| Buchhalter, J | 1 |
| Scheffer, IE | 1 |
| Cilingir-Kaya, OT | 1 |
| Moore, C | 1 |
| Meshul, CK | 3 |
| Gursoy, D | 1 |
| Akyuz, E | 1 |
| Ozenen, C | 1 |
| Pinyazhko, OR | 1 |
| Poshyvak, OB | 1 |
| Godlevsky, LS | 1 |
| Panthi, S | 1 |
| Lyons, NMA | 1 |
| Bombardi, C | 1 |
| Venzi, M | 1 |
| Crunelli, V | 4 |
| Di Giovanni, G | 1 |
| Çavdar, S | 4 |
| Bay, HH | 2 |
| Kirazlı, Ö | 1 |
| Çakmak, YÖ | 2 |
| Zhou, C | 1 |
| Huang, Z | 1 |
| Ding, L | 1 |
| Deel, ME | 1 |
| Arain, FM | 1 |
| Murray, CR | 1 |
| Patel, RS | 1 |
| Flanagan, CD | 1 |
| Gallagher, MJ | 1 |
| Yildiz, SD | 2 |
| Hammad, M | 1 |
| Schmidt, SL | 1 |
| Zhang, X | 1 |
| Bray, R | 1 |
| Frohlich, F | 1 |
| Ghashghaei, HT | 1 |
| Chen, M | 1 |
| Guo, D | 1 |
| Li, M | 1 |
| Ma, T | 1 |
| Wu, S | 1 |
| Ma, J | 1 |
| Cui, Y | 1 |
| Xia, Y | 1 |
| Xu, P | 1 |
| Yao, D | 1 |
| Tanaka, M | 1 |
| Olsen, RW | 2 |
| Medina, MT | 1 |
| Schwartz, E | 1 |
| Alonso, ME | 1 |
| Duron, RM | 1 |
| Castro-Ortega, R | 1 |
| Martinez-Juarez, IE | 1 |
| Pascual-Castroviejo, I | 1 |
| Machado-Salas, J | 1 |
| Silva, R | 1 |
| Bailey, JN | 1 |
| Bai, D | 1 |
| Ochoa, A | 1 |
| Jara-Prado, A | 1 |
| Pineda, G | 1 |
| Macdonald, RL | 2 |
| Delgado-Escueta, AV | 1 |
| Pisu, MG | 1 |
| Mostallino, MC | 1 |
| Dore, R | 1 |
| Mura, ML | 1 |
| Maciocco, E | 1 |
| Russo, E | 1 |
| De Sarro, G | 1 |
| Serra, M | 1 |
| Castillo, CG | 1 |
| Mendoza, S | 1 |
| Saavedra, J | 1 |
| Giordano, M | 1 |
| Brockhaus, J | 1 |
| Pape, HC | 2 |
| Gurbanova, A | 1 |
| Aker, R | 1 |
| San, T | 4 |
| Hacıoğlu, H | 1 |
| Doğukan, SY | 1 |
| Koppert, MM | 1 |
| Kalitzin, S | 1 |
| Lopes da Silva, FH | 2 |
| Viergever, MA | 1 |
| Canillioglu, Y | 1 |
| Midillioglu, S | 1 |
| Yalçın, O | 1 |
| Gurba, KN | 1 |
| Hernandez, CC | 1 |
| Hu, N | 1 |
| Gralewicz, S | 1 |
| Lin, SH | 1 |
| Arai, AC | 1 |
| España, RA | 1 |
| Berridge, CW | 1 |
| Leslie, FM | 1 |
| Huguenard, JR | 3 |
| Vergnes, M | 7 |
| Civelli, O | 1 |
| Posner, E | 4 |
| Destexhe, A | 1 |
| Sejnowski, TJ | 1 |
| Steriade, M | 1 |
| Amzica, F | 1 |
| French, JA | 1 |
| Kanner, AM | 1 |
| Bautista, J | 1 |
| Abou-Khalil, B | 1 |
| Browne, T | 1 |
| Harden, CL | 1 |
| Theodore, WH | 1 |
| Bazil, C | 1 |
| Stern, J | 1 |
| Schachter, SC | 1 |
| Bergen, D | 1 |
| Hirtz, D | 1 |
| Montouris, GD | 1 |
| Nespeca, M | 1 |
| Gidal, B | 1 |
| Marks, WJ | 1 |
| Turk, WR | 1 |
| Fischer, JH | 1 |
| Bourgeois, B | 1 |
| Wilner, A | 1 |
| Faught, RE | 1 |
| Sachdeo, RC | 1 |
| Beydoun, A | 1 |
| Glauser, TA | 1 |
| Wu, J | 1 |
| Ellsworth, K | 1 |
| Ellsworth, M | 1 |
| Schroeder, KM | 1 |
| Smith, K | 1 |
| Fisher, RS | 1 |
| Slaght, SJ | 1 |
| Paz, T | 1 |
| Chavez, M | 1 |
| Deniau, JM | 1 |
| Mahon, S | 1 |
| Charpier, S | 1 |
| Badiu, CI | 2 |
| Rainesalo, S | 1 |
| Eriksson, K | 1 |
| Saransaari, P | 1 |
| Keränen, T | 1 |
| Nail-Boucherie, K | 1 |
| Lê-Pham, BT | 2 |
| Gobaille, S | 1 |
| Maitre, M | 2 |
| Aunis, D | 1 |
| Depaulis, A | 7 |
| Ai, J | 1 |
| Hampson, DR | 1 |
| Snead, OC | 9 |
| Maris, E | 2 |
| Bouwman, BM | 2 |
| Suffczynski, P | 2 |
| van Rijn, CM | 2 |
| Gibson, KM | 1 |
| Jakobs, C | 1 |
| Pearl, PL | 1 |
| Emri, Z | 1 |
| Leresche, N | 3 |
| Marrosu, F | 1 |
| Santoni, F | 1 |
| Fà, M | 1 |
| Puligheddu, M | 1 |
| Barberini, L | 1 |
| Genugu, F | 1 |
| Frau, R | 1 |
| Manunta, M | 1 |
| Mereu, G | 1 |
| Terzioğlu, B | 2 |
| Aypak, C | 2 |
| Onat, FY | 3 |
| Küçükibrahimoğlu, E | 1 |
| Ozkaynakçi, AE | 2 |
| Gören, MZ | 2 |
| Melø, TM | 2 |
| Sonnewald, U | 2 |
| Touret, M | 1 |
| Nehlig, A | 3 |
| Payne, HL | 1 |
| Donoghue, PS | 1 |
| Connelly, WM | 1 |
| Hinterreiter, S | 1 |
| Tiwari, P | 1 |
| Ives, JH | 1 |
| Hann, V | 1 |
| Sieghart, W | 1 |
| Lees, G | 1 |
| Thompson, CL | 1 |
| Aker, RG | 2 |
| Ozyurt, HB | 1 |
| Yananli, HR | 2 |
| Sehirli, U | 1 |
| Saka, E | 1 |
| Bessaïh, T | 2 |
| Bourgeais, L | 1 |
| Carter, DA | 1 |
| Toth, TI | 2 |
| Ruano, D | 1 |
| Lambolez, B | 1 |
| Mares, P | 1 |
| Slamberová, R | 1 |
| Tolmacheva, EA | 1 |
| van Luijtelaar, G | 2 |
| Wu, Y | 1 |
| Chan, KF | 1 |
| Eubanks, JH | 1 |
| Guin Ting Wong, C | 1 |
| Cortez, MA | 2 |
| Shen, L | 1 |
| Che Liu, C | 1 |
| Perez Velazquez, J | 1 |
| Tian Wang, Y | 1 |
| Jia, Z | 2 |
| Carter Snead, O | 1 |
| Bastholm, IA | 1 |
| Tan, HO | 1 |
| Reid, CA | 1 |
| Chiu, C | 1 |
| Jones, MV | 1 |
| Petrou, S | 1 |
| Spero, L | 1 |
| Marescaux, C | 9 |
| Micheletti, G | 1 |
| Rumbach, L | 1 |
| Warter, JM | 1 |
| Richards, DA | 1 |
| Lemos, T | 1 |
| Whitton, PS | 1 |
| Bowery, NG | 2 |
| Lin, FH | 1 |
| Wang, Y | 2 |
| Lin, S | 1 |
| Cao, Z | 1 |
| Hosford, DA | 4 |
| Banerjee, PK | 4 |
| Vogt, H | 1 |
| Krämer, G | 1 |
| Wallenstein, GV | 1 |
| Fromm, GH | 1 |
| Kishi, K | 1 |
| Ito, M | 1 |
| Tsuda, A | 1 |
| Tsuda, H | 1 |
| Shiraishi, H | 1 |
| Sejima, H | 1 |
| Mori, C | 1 |
| Serikawa, T | 1 |
| Yamada, J | 1 |
| Luhmann, HJ | 1 |
| Mittmann, T | 1 |
| Heinemann, U | 1 |
| Caddick, SJ | 2 |
| Avanzini, G | 1 |
| de Curtis, M | 1 |
| Franceschetti, S | 1 |
| Sancini, G | 1 |
| Spreafico, R | 1 |
| Trudeau, V | 1 |
| Myers, S | 1 |
| LaMoreaux, L | 1 |
| Anhut, H | 1 |
| Garofalo, E | 1 |
| Ebersole, J | 1 |
| Panayiotopoulos, CP | 2 |
| Agathonikou, A | 2 |
| Sharoqi, IA | 1 |
| Parker, AP | 2 |
| Robinson, RO | 1 |
| Deransart, C | 2 |
| Vercueil, L | 1 |
| Tillakaratne, NJ | 1 |
| Brailowsky, S | 2 |
| Tobin, AJ | 1 |
| Cocito, L | 2 |
| Primavera, A | 1 |
| Liu, CC | 1 |
| de Toffol, B | 1 |
| Hommet, C | 1 |
| Corcia, P | 1 |
| Autret, A | 1 |
| Wang, C | 1 |
| Fletcher, CF | 1 |
| Jenkins, NA | 1 |
| Copeland, NG | 1 |
| Montiel, T | 1 |
| Boehrer, A | 3 |
| Parry, K | 1 |
| Mathivet, P | 1 |
| Bernasconi, R | 1 |
| Reibel, S | 1 |
| Simler, S | 1 |
| Hu, RQ | 2 |
| Staak, R | 1 |
| Man, HY | 1 |
| Roder, J | 1 |
| Wang, YT | 1 |
| Hirsch, E | 1 |
| Bassilios, N | 1 |
| Launay-Vacher, V | 1 |
| Khoury, N | 1 |
| Rondeau, E | 1 |
| Deray, G | 1 |
| Sraer, JD | 1 |
| Dufour, F | 1 |
| Nalecz, KA | 1 |
| Nalecz, MJ | 1 |
| King, GA | 1 |
| Bruni, J | 1 |
| Wilder, BJ | 1 |
| Pinder, RM | 1 |
| Brogden, RN | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Liu, Z | 2 |
| Ortiz, JG | 2 |
| Negrón, AE | 2 |
| Thomas, AP | 2 |
| Cordero, ML | 2 |
| García, MT | 1 |
| Maldonado, CS | 1 |
| Heimer, H | 2 |
| Moreira, JA | 2 |
| Aranda, J | 2 |
| Santiago, G | 1 |
| Bruno, MS | 1 |
| Smith, KA | 2 |
| Bierkamper, GG | 2 |
| Jobe, PC | 1 |
| Mishra, PK | 1 |
| Ludvig, N | 1 |
| Dailey, JW | 1 |
| Hechler, V | 1 |
| Coulter, DA | 2 |
| Prince, DA | 2 |
| Kurlemann, G | 1 |
| Palm, DG | 1 |
| Mirsky, AF | 1 |
| Duncan, CC | 1 |
| Myslobodsky, MS | 1 |
| Loeb, C | 1 |
| Benassi, E | 1 |
| Bo, GP | 1 |
| Maffini, M | 1 |
| Scotto, P | 1 |
| Yamamoto, M | 1 |
| Takahashi, S | 1 |
| Otsuki, S | 1 |
| Kugoh, T | 1 |
| Hosokawa, K | 1 |
| Ogawa, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phenylbutyrate for Monogenetic Developmental and Epileptic Encephalopathy[NCT04937062] | Early Phase 1 | 50 participants (Anticipated) | Interventional | 2021-03-01 | Enrolling by invitation | ||
| Phase 3: Metabolism of Lamotrigine During Treatment With Oral Contraceptives[NCT00266149] | Phase 3 | 10 participants | Interventional | 2003-06-30 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
19 reviews available for gamma-aminobutyric acid and Epilepsy, Absence
| Article | Year |
|---|---|
Cerebellar contribution to absence epilepsy.
Topics: Action Potentials; Animals; Cerebellum; Epilepsy, Absence; gamma-Aminobutyric Acid; Humans | 2021 |
Genes and molecular mechanisms involved in the epileptogenesis of idiopathic absence epilepsies.
Topics: Adolescent; Alleles; Animals; Calcium Channels; Child; Disease Models, Animal; Epilepsy, Absence; ga | 2012 |
[Petit-mal epilepsy in laboratory rats, issues that an experimenter should be remember].
Topics: Animals; Disease Models, Animal; Electroencephalography; Energy Metabolism; Epilepsy, Absence; Evoke | 2002 |
Absence seizures in children.
Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximi | 2002 |
Efficacy and tolerability of the new antiepileptic drugs, I: Treatment of new-onset epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society.
Topics: Acetates; Adolescent; Adult; Age Factors; Amines; Antipsychotic Agents; Carbamazepine; Child; Clinic | 2004 |
Absence seizures in children.
Topics: Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabape | 2003 |
Absence seizures in children.
Topics: Adolescent; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuxi | 2004 |
Absence seizures in children.
Topics: Adolescent; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy, | 2005 |
Murine succinate semialdehyde dehydrogenase (SSADH) deficiency, a heritable disorder of GABA metabolism with epileptic phenotype.
Topics: Animals; Disease Models, Animal; Epilepsy, Absence; gamma-Aminobutyric Acid; Humans; Metabolism, Inb | 2005 |
Unravelling the brain targets of gamma-hydroxybutyric acid.
Topics: Animals; Brain; Epilepsy, Absence; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Humans; Hydrox | 2006 |
[Vigabatrin and lamotrigin: experiences with 2 new anticonvulsants in the Swiss epilepsy clinic].
Topics: 4-Aminobutyrate Transaminase; Adult; Anticonvulsants; Child; Drug Therapy, Combination; Epilepsies, | 1995 |
Gabapentin: discussion.
Topics: Acetates; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drugs, Inv | 1994 |
The role of GABAB mechanisms in animal models of absence seizures.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Epilepsy, Absence; GABA Agonists; GABA Antagonists; gamma | 1996 |
The role of basal ganglia in the control of generalized absence seizures.
Topics: Animals; Basal Ganglia; Brain; Epilepsy, Absence; gamma-Aminobutyric Acid; Humans; Models, Neurologi | 1998 |
[Anticonvulsants can aggravate idiopathic generalized epilepsy].
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Epilepsies, Myoclonic; Epilepsy, Ab | 1998 |
Valproic acid. Review of a new antiepileptic drug.
Topics: Adolescent; Adult; Animals; Brain Chemistry; Drug Interactions; Electric Stimulation; Electroencepha | 1979 |
Sodium valproate: a review of its pharmacological properties and therapeutic efficacy in epilepsy.
Topics: Administration, Oral; Adult; Animals; Anticonvulsants; Behavior; Blood Platelets; Child; Clinical Tr | 1977 |
Scope and contribution of genetic models to an understanding of the epilepsies.
Topics: Animals; Catecholamines; Disease Models, Animal; Epilepsy; Epilepsy, Absence; gamma-Aminobutyric Aci | 1991 |
Petit mal epilepsy: a review and integration of recent information.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Brain; Cognition; Dementia; Electroencephalogra | 1986 |
2 trials available for gamma-aminobutyric acid and Epilepsy, Absence
| Article | Year |
|---|---|
Gabapentin in naive childhood absence epilepsy: results from two double-blind, placebo-controlled, multicenter studies.
Topics: Acetates; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Dose-Respon | 1996 |
Sodium valproate: a review of its pharmacological properties and therapeutic efficacy in epilepsy.
Topics: Administration, Oral; Adult; Animals; Anticonvulsants; Behavior; Blood Platelets; Child; Clinical Tr | 1977 |
90 other studies available for gamma-aminobutyric acid and Epilepsy, Absence
| Article | Year |
|---|---|
Vasoactive intestinal peptide (VIP) conducts the neuronal activity during absence seizures: GABA seems to be the main mediator of VIP.
Topics: Animals; Epilepsy, Absence; Female; gamma-Aminobutyric Acid; Rats; Rats, Wistar; Seizures; Somatosen | 2021 |
Astrocytic GABA transporter 1 deficit in novel SLC6A1 variants mediated epilepsy: Connected from protein destabilization to seizures in mice and humans.
Topics: Animals; Astrocytes; Epilepsies, Myoclonic; Epilepsy, Absence; GABA Plasma Membrane Transport Protei | 2022 |
Altered GABA
Topics: Animals; Disease Models, Animal; Epilepsy, Absence; gamma-Aminobutyric Acid; Mice; Receptors, GABA-A | 2022 |
Developmental Inhibitory Changes in the Primary Somatosensory Cortex of the Stargazer Mouse Model of Absence Epilepsy.
Topics: Animals; Epilepsy, Absence; gamma-Aminobutyric Acid; Mice; Receptors, GABA-A; Seizures; Somatosensor | 2023 |
Endoplasmic reticulum retention and degradation of a mutation in SLC6A1 associated with epilepsy and autism.
Topics: Amino Acid Sequence; Animals; Autistic Disorder; Cell Line; Child; Electroencephalography; Endoplasm | 2020 |
Ultrastructural GABA immunogold labeling in the substantia nigra pars reticulata of kindled genetic absence epilepsy rats.
Topics: Animals; Disease Models, Animal; Epilepsy, Absence; gamma-Aminobutyric Acid; Immunohistochemistry; K | 2020 |
Contribution of rare genetic variants to drug response in absence epilepsy.
Topics: Anticonvulsants; Epilepsy, Absence; Ethosuximide; gamma-Aminobutyric Acid; Humans; Pharmaceutical Pr | 2021 |
Neurogenesis is Enhanced in Young Rats with Genetic Absence Epilepsy: An Immuno-electron Microscopic Study.
Topics: Animals; Doublecortin Protein; Epilepsy, Absence; gamma-Aminobutyric Acid; Hippocampus; Immunohistoc | 2021 |
Impact of Dysfunctional Feed-Forward Inhibition on Glutamate Decarboxylase Isoforms and γ-Aminobutyric Acid Transporters.
Topics: Animals; Disease Models, Animal; Epilepsy, Absence; Female; gamma-Aminobutyric Acid; Glutamate Decar | 2021 |
Developmental changes of GABA immunoreactivity in cortico-thalamic networks of an absence seizure model.
Topics: Animals; Cerebral Cortex; Disease Models, Animal; Epilepsy, Absence; GABAergic Neurons; gamma-Aminob | 2018 |
Comparing GABAergic cell populations in the thalamic reticular nucleus of normal and genetic absence epilepsy rats from Strasbourg (GAERS).
Topics: Animals; Cell Count; Disease Models, Animal; Epilepsy, Absence; GABAergic Neurons; gamma-Aminobutyri | 2013 |
Altered cortical GABAA receptor composition, physiology, and endocytosis in a mouse model of a human genetic absence epilepsy syndrome.
Topics: Alleles; Animals; Benzodiazepines; Cell Membrane; Cerebral Cortex; Chlorocebus aethiops; COS Cells; | 2013 |
Comparison of numbers of interneurons in three thalamic nuclei of normal and epileptic rats.
Topics: Animals; Cell Count; Disease Models, Animal; Epilepsy, Absence; gamma-Aminobutyric Acid; Interneuron | 2014 |
Transplantation of GABAergic Interneurons into the Neonatal Primary Visual Cortex Reduces Absence Seizures in Stargazer Mice.
Topics: Animals; Calcium Channels; Disease Models, Animal; Embryo, Mammalian; Epilepsy, Absence; GABAergic N | 2015 |
Critical Roles of the Direct GABAergic Pallido-cortical Pathway in Controlling Absence Seizures.
Topics: Biological Clocks; Cerebral Cortex; Computer Simulation; Epilepsy, Absence; Feedback, Physiological; | 2015 |
Hyperglycosylation and reduced GABA currents of mutated GABRB3 polypeptide in remitting childhood absence epilepsy.
Topics: Amino Acid Sequence; Cell Line; Child; Child, Preschool; DNA Mutational Analysis; DNA, Complementary | 2008 |
Neuroactive steroids and GABAA receptor plasticity in the brain of the WAG/Rij rat, a model of absence epilepsy.
Topics: Aging; Animals; Animals, Genetically Modified; Brain; Brain Chemistry; Cerebral Cortex; Desoxycortic | 2008 |
Lack of effect of intranigral transplants of a GABAergic cell line on absence seizures.
Topics: Animals; Body Weight; Cell Line; Cell Transplantation; Disease Models, Animal; Epilepsy, Absence; ga | 2010 |
Abnormalities in GABAergic synaptic transmission of intralaminar thalamic neurons in a genetic rat model of absence epilepsy.
Topics: Animals; Disease Models, Animal; Epilepsy, Absence; gamma-Aminobutyric Acid; Inhibitory Postsynaptic | 2011 |
Ultrastructural GABA immunocytochemistry in the mossy fiber terminals of Wistar and genetic absence epileptic rats receiving amygdaloid kindling stimulations.
Topics: Amygdala; Animals; Dentate Gyrus; Disease Models, Animal; Epilepsy, Absence; Epilepsy, Temporal Lobe | 2011 |
Do the quantitative relationships of synaptic junctions and terminals in the thalamus of genetic absence epilepsy rats from Strasbourg (GAERS) differ from those in normal control Wistar rats.
Topics: Animals; Disease Models, Animal; Epilepsy, Absence; gamma-Aminobutyric Acid; Microscopy, Electron, T | 2012 |
Plasticity-modulated seizure dynamics for seizure termination in realistic neuronal models.
Topics: Algorithms; Animals; Cyclic Nucleotide-Gated Cation Channels; Epilepsy, Absence; gamma-Aminobutyric | 2011 |
Glutamic acid decarboxylase immunoreactivity in the mossy fiber terminals of the hippocampus of genetic absence epileptic rats.
Topics: Animals; CA3 Region, Hippocampal; Dentate Gyrus; Disease Models, Animal; Epilepsy, Absence; gamma-Am | 2011 |
GABRB3 mutation, G32R, associated with childhood absence epilepsy alters α1β3γ2L γ-aminobutyric acid type A (GABAA) receptor expression and channel gating.
Topics: Amino Acid Sequence; Cell Membrane; Epilepsy, Absence; gamma-Aminobutyric Acid; Glycosylation; HEK29 | 2012 |
Prolactin-releasing peptide (PrRP) promotes awakening and suppresses absence seizures.
Topics: Action Potentials; Animals; Biological Clocks; Electroencephalography; Epilepsy, Absence; gamma-Amin | 2002 |
The initiation of bursts in thalamic neurons and the cortical control of thalamic sensitivity.
Topics: Action Potentials; Animals; Cerebral Cortex; Epilepsy, Absence; gamma-Aminobutyric Acid; Glutamic Ac | 2002 |
Immunocytochemical analysis of glutamate and GABA in hippocampus of genetic absence epilepsy rats (GAERS).
Topics: Animals; Epilepsy, Absence; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Immunohistochemistr | 2003 |
Sleep oscillations developing into seizures in corticothalamic systems.
Topics: Animals; Cats; Cerebral Cortex; Diagnosis, Differential; Electroencephalography; Epilepsy, Absence; | 2003 |
Abnormal benzodiazepine and zinc modulation of GABAA receptors in an acquired absence epilepsy model.
Topics: Androstenes; Animals; Anticonvulsants; Benzodiazepines; Diazepam; Disease Models, Animal; Enzyme Inh | 2004 |
On the activity of the corticostriatal networks during spike-and-wave discharges in a genetic model of absence epilepsy.
Topics: Action Potentials; Afferent Pathways; Animals; Basal Ganglia; Cerebral Cortex; Chlorides; Corpus Str | 2004 |
Sensitivity of thalamic GABAergic currents to clonazepam does not differ between control and genetic absence epilepsy rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Antic | 2004 |
Uptake of GABA and activity of GABA transaminase in blood platelets from children with absence epilepsy.
Topics: 4-Aminobutyrate Transaminase; Adolescent; Blood Platelets; Child; Child, Preschool; Dose-Response Re | 2004 |
Evidence for a role of the parafascicular nucleus of the thalamus in the control of epileptic seizures by the superior colliculus.
Topics: Animals; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Excitatory Amino Acid Ag | 2005 |
Glutamate and GABA immunocytochemical electron microscopy in the hippocampal dentate gyrus of normal and genetic absence epilepsy rats.
Topics: Animals; Dentate Gyrus; Epilepsy, Absence; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemis | 2005 |
Altered glutamate and GABA release within thalamocortical circuitry in metabotropic glutamate receptor 4 knockout mice.
Topics: Animals; Cerebral Cortex; Epilepsy, Absence; gamma-Aminobutyric Acid; Glutamic Acid; Mice; Mice, Kno | 2005 |
Starting and stopping mechanisms of absence epileptic seizures are revealed by hazard functions.
Topics: Algorithms; Animals; Anticonvulsants; Data Interpretation, Statistical; Electroencephalography; Epil | 2006 |
Beta and gamma range EEG power-spectrum correlation with spiking discharges in DBA/2J mice absence model: role of GABA receptors.
Topics: Alpha Rhythm; Animals; Baclofen; Beta Rhythm; Cerebral Cortex; Cognition; Cortical Synchronization; | 2006 |
The effects of ethosuximide on amino acids in genetic absence epilepsy rat model.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Ethosux | 2006 |
Cortical glutamate metabolism is enhanced in a genetic model of absence epilepsy.
Topics: Animals; Astrocytes; Brain; Epilepsy, Absence; gamma-Aminobutyric Acid; Glutamic Acid; Learning; Mag | 2006 |
Aberrant GABA(A) receptor expression in the dentate gyrus of the epileptic mutant mouse stargazer.
Topics: Animals; Calcium Channels; Cells, Cultured; Dentate Gyrus; Electrophysiology; Epilepsy, Absence; gam | 2006 |
GABA(A) receptor mediated transmission in the thalamic reticular nucleus of rats with genetic absence epilepsy shows regional differences: functional implications.
Topics: Action Potentials; Afferent Pathways; Animals; Basal Ganglia; Bicuculline; Cerebral Cortex; Disease | 2006 |
Nucleus-specific abnormalities of GABAergic synaptic transmission in a genetic model of absence seizures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Epilepsy, Absence; Excitatory Postsynaptic | 2006 |
Opposite effects of a GABA(B) antagonist in two models of epileptic seizures in developing rats.
Topics: Action Potentials; Aging; Animals; Animals, Newborn; Cerebral Cortex; Convulsants; Disease Models, A | 2006 |
Absence seizures are reduced by the enhancement of GABA-ergic inhibition in the hippocampus in WAG/Rij rats.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; Epi | 2007 |
Transgenic mice over-expressing GABA(B)R1a receptors acquire an atypical absence epilepsy-like phenotype.
Topics: Action Potentials; Animals; Behavior, Animal; Brain; Brain Chemistry; Disease Models, Animal; Epilep | 2007 |
GABAergic mechanisms in absence epilepsy: a computational model of absence epilepsy simulating spike and wave discharges after vigabatrin in WAG/Rij rats.
Topics: Action Potentials; Animals; Animals, Genetically Modified; Anticonvulsants; Brain; Computer Simulati | 2007 |
Astrocytes may play a role in the etiology of absence epilepsy: a comparison between immature GAERS not yet expressing seizures and adults.
Topics: Acetic Acid; Aging; Animals; Astrocytes; Brain; Cell Communication; Cell Differentiation; Disease Mo | 2007 |
The properties of reticular thalamic neuron GABA(A) IPSCs of absence epilepsy rats lead to enhanced network excitability.
Topics: Action Potentials; Animals; Disease Models, Animal; Dose-Response Relationship, Radiation; Electric | 2007 |
Extracellular hypothalamic gamma-aminobutyric acid (GABA) and L-glutamic acid concentrations in response to bicuculline in a genetic absence epilepsy rat model.
Topics: Animals; Bicuculline; Blood Pressure; Convulsants; Disease Models, Animal; Electroencephalography; E | 2008 |
Increased thalamic inhibition in the absence seizure prone DBA/2J mouse.
Topics: Animals; Brain Mapping; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Epilepsy, A | 2008 |
Epilepsy.
Topics: Anticonvulsants; Brain; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; gamma-Aminobutyric Acid | 1982 |
Enhancement of spike and wave discharges by GABAmimetic drugs in rats with spontaneous petit-mal-like epilepsy.
Topics: Action Potentials; Aminocaproates; Animals; Baclofen; Epilepsy, Absence; gamma-Aminobutyric Acid; Is | 1984 |
Extracellular GABA in the ventrolateral thalamus of rats exhibiting spontaneous absence epilepsy: a microdialysis study.
Topics: Animals; Baclofen; Electroencephalography; Epilepsy, Absence; Extracellular Space; GABA Antagonists; | 1995 |
GABAB receptor-mediated effects in synaptosomes of lethargic (lh/lh) mice.
Topics: Animals; Calcium; Cerebral Cortex; Colforsin; Cyclic AMP; Epilepsy; Epilepsy, Absence; gamma-Aminobu | 1995 |
Presynaptic gamma-hydroxybutyric acid (GHB) and gamma-aminobutyric acidB (GABAB) receptor-mediated release of GABA and glutamate (GLU) in rat thalamic ventrobasal nucleus (VB): a possible mechanism for the generation of absence-like seizures induced by GH
Topics: Action Potentials; Animals; Baclofen; Epilepsy, Absence; Extracellular Space; GABA-B Receptor Antago | 1995 |
The ontogeny of [3H]gamma-hydroxybutyrate and [3H]GABAB binding sites: relation to the development of experimental absence seizures.
Topics: 4-Butyrolactone; Animals; Animals, Newborn; Binding Sites; Electrophysiology; Epilepsy, Absence; gam | 1994 |
The role of thalamic IGABAB in generating spike-wave discharges during petit mal seizures.
Topics: Animals; Bicuculline; Cats; Computer Simulation; Electroencephalography; Epilepsy, Absence; gamma-Am | 1994 |
GABA-gated chloride ion influx in brains of tremor rats.
Topics: Animals; Brain; Cerebral Cortex; Chlorides; Epilepsy, Absence; Frontal Lobe; gamma-Aminobutyric Acid | 1993 |
Impairment of intracortical GABAergic inhibition in a rat model of absence epilepsy.
Topics: Animals; Cerebral Cortex; Electroencephalography; Electrophysiology; Epilepsy, Absence; gamma-Aminob | 1995 |
Cortical versus thalamic mechanisms underlying spike and wave discharges in GAERS.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cerebral Cortex; Disease | 1996 |
Utility of the lethargic (lh/lh) mouse model of absence seizures in predicting the effects of lamotrigine, vigabatrin, tiagabine, gabapentin, and topiramate against human absence seizures.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dru | 1997 |
Vigabatrin aggravates absences and absence status.
Topics: Adult; Anticonvulsants; Electroencephalography; Epilepsy, Absence; Epilepsy, Generalized; gamma-Amin | 1997 |
Inappropriate use of carbamazepine and vigabatrin in typical absence seizures.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsies, Myoclon | 1998 |
Absence seizures decrease steroid modulation of t-[35S]butylbicyclophosphorothionate binding in thalamic relay nuclei.
Topics: Action Potentials; Animals; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Desoxycorticoste | 1998 |
Vigabatrin aggravates absences and absence status.
Topics: Adult; Anticonvulsants; Asphyxia; Brain Damage, Chronic; Carbamazepine; Drug Therapy, Combination; E | 1998 |
Steroid-inhibition of [3H]gamma-hydroxybutyric acid (GHB) binding in thalamic relay nuclei increases during absence seizures.
Topics: Anesthetics; Animals; Binding, Competitive; Cerebral Cortex; Desoxycorticosterone; Epilepsy, Absence | 1998 |
Excitatory but not inhibitory synaptic transmission is reduced in lethargic (Cacnb4(lh)) and tottering (Cacna1atg) mouse thalami.
Topics: Animals; Calcium Channels; Calcium Channels, N-Type; Calcium Channels, P-Type; Calcium Channels, Q-T | 1999 |
Susceptibility to focal and generalized seizures in Wistar rats with genetic absence-like epilepsy.
Topics: Animals; Convulsants; Electroencephalography; Epilepsies, Partial; Epilepsy, Absence; Epilepsy, Gene | 1999 |
Pertussis toxin decreases absence seizures and GABA(B) receptor binding in thalamus of a genetically prone rat (GAERS).
Topics: Animals; Electroencephalography; Epilepsy, Absence; gamma-Aminobutyric Acid; GTP-Binding Proteins; M | 1999 |
Selective susceptibility to inhibitors of GABA synthesis and antagonists of GABA(A) receptor in rats with genetic absence epilepsy.
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Carbolines; Convulsants; Electroencephalography; Epi | 2000 |
Regulation of gamma-aminobutyric acid (GABA) release in cerebral cortex in the gamma-hydroxybutyric acid (GHB) model of absence seizures in rat.
Topics: 4-Butyrolactone; Animals; Cerebral Cortex; Electroencephalography; Epilepsy, Absence; GABA Antagonis | 2000 |
Contribution of GABA(A) and GABA(B) receptors to thalamic neuronal activity during spontaneous absence seizures in rats.
Topics: Action Potentials; Animals; Bicuculline; Disease Models, Animal; Electroencephalography; Epilepsy, A | 2001 |
Gamma-hydroxybutyric acid-induced absence seizures in GluR2 null mutant mice.
Topics: Animals; Blotting, Western; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; gamma | 2001 |
Inhibition of the substantia nigra suppresses absences and clonic seizures in audiogenic rats, but not tonic seizures: evidence for seizure specificity of the nigral control.
Topics: Acoustic Stimulation; Animals; Auditory Pathways; Electroencephalography; Epilepsy, Absence; Epileps | 2001 |
Gabapentin neurotoxicity in a chronic haemodialysis patient.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Epilepsy, Absence; | 2001 |
Metabolic approach of absence seizures in a genetic model of absence epilepsy, the GAERS: study of the leucine-glutamate cycle.
Topics: Acetates; Amines; Amino Acids, Branched-Chain; Animals; Brain; Carbon Monoxide; Cells, Cultured; Cer | 2001 |
Effects of systemically applied GABA agonists and antagonists on wave-spike ECoG activity in rat.
Topics: Action Potentials; Animals; Behavior, Animal; Bicuculline; Electroencephalography; Epilepsy, Absence | 1979 |
Involvement of intrathalamic GABAB neurotransmission in the control of absence seizures in the rat.
Topics: Animals; Baclofen; Electroencephalography; Epilepsy, Absence; GABA-A Receptor Antagonists; gamma-Ami | 1992 |
The inhibitory control of the substantia nigra over generalized non-convulsive seizures in the rat.
Topics: Animals; Brain Mapping; Disease Models, Animal; Dopamine; Epilepsy, Absence; gamma-Aminobutyric Acid | 1992 |
GABA and glutamate neurotransmission in the C57BL/10 sps/sps mouse: a mutant with absence-like behavior.
Topics: Animals; Brain; Brain Mapping; Epilepsy, Absence; Female; gamma-Aminobutyric Acid; Glutamate Decarbo | 1992 |
Evidence for a critical role of GABAergic transmission within the thalamus in the genesis and control of absence seizures in the rat.
Topics: Aminocaproates; Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Epilepsy, | 1991 |
GABAergic neurotransmission in the C57BL/10 sps/sps mouse mutant: a model of absence seizures.
Topics: Animals; Brain; Epilepsy, Absence; gamma-Aminobutyric Acid; Mice; Mice, Mutant Strains; Synaptic Tra | 1991 |
Paradoxical role of GABA in a chronic model of petit mal (absence)-like epilepsy in the rat.
Topics: Animals; Anticonvulsants; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; | 1990 |
Increased gamma-hydroxybutyric acid receptors in thalamus of a genetic animal model of petit mal epilepsy.
Topics: Animals; Autoradiography; Binding Sites; Electroencephalography; Epilepsy, Absence; gamma-Aminobutyr | 1990 |
Differential effects of petit mal anticonvulsants and convulsants on thalamic neurones: GABA current blockade.
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Epilepsy, Absence; Ethosuximide; gamma-Aminobuty | 1990 |
Differential effects of petit mal anticonvulsants and convulsants on thalamic neurones: calcium current reduction.
Topics: Animals; Anticonvulsants; Calcium Channels; Convulsants; Epilepsy, Absence; Ethosuximide; gamma-Amin | 1990 |
[Decrease of plasma prolactin in valproate therapy--expression of an increase in the activity of the central GABAergic system].
Topics: Adolescent; Brain; Child; Child, Preschool; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Female; gamma | 1987 |
Anticonvulsant drug activity in a rat model of absence epilepsy.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsy, Absence; gamma-Aminobutyric Acid; Rats | 1987 |
Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Epilepsy; Epilepsy, Absence; Female; gamma-Aminobutyric Ac | 1987 |
GABA levels in cerebrospinal fluid of patients with epilepsy.
Topics: Adult; Cerebellar Ataxia; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Female; gamma-Aminobutyr | 1985 |