Page last updated: 2024-10-16

gamma-aminobutyric acid and Encephalomyopathies, Mitochondrial

gamma-aminobutyric acid has been researched along with Encephalomyopathies, Mitochondrial in 2 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dager, SR1
Friedman, SD1
Parow, A1
Demopulos, C1
Stoll, AL1
Lyoo, IK1
Dunner, DL1
Renshaw, PF1
Celebi, N1
Sahin, A1
Canbay, O1
Uzümcügil, F1
Aypar, U1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Imaging Framework for Testing GABAergic/Glutamatergic Drugs in Bipolar Alcoholics[NCT03220776]Phase 254 participants (Actual)Interventional2017-08-07Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Prefrontal GABA+ Concentrations

Concentrations of GABA+, referenced to unsuppressed water and corrected for within-voxel CSF proportion, in dorsal anterior cingulate cortex measured via Proton Magnetic Resonance Spectroscopy (i.e., MEGA-PRESS). (NCT03220776)
Timeframe: Day 5 of each experimental condition

Interventionmmol/kg (Mean)
N-Acetylcysteine3.90
Gabapentin3.93
Placebo Oral Tablet3.73

Prefrontal Glx Concentrations

Concentrations of Glx (i.e., glutamate + glutamine), referenced to unsuppressed water and corrected for within-voxel CSF proportion, in dorsal anterior cingulate cortex measured via Proton Magnetic Resonance Spectroscopy. (NCT03220776)
Timeframe: Day 5 of each experimental condition

Interventionmmol/kg (Mean)
N-Acetylcysteine21.59
Gabapentin21.69
Placebo Oral Tablet22.25

Other Studies

2 other studies available for gamma-aminobutyric acid and Encephalomyopathies, Mitochondrial

ArticleYear
Brain metabolic alterations in medication-free patients with bipolar disorder.
    Archives of general psychiatry, 2004, Volume: 61, Issue:5

    Topics: Adult; Ambulatory Care; Bipolar Disorder; Brain; Brain Chemistry; Creatine; Echo-Planar Imaging; Fem

2004
Abdominal pain related to mitochondrial neurogastrointestinal encephalomyopathy syndrome may benefit from splanchnic nerve blockade.
    Paediatric anaesthesia, 2006, Volume: 16, Issue:10

    Topics: Abdominal Pain; Adolescent; Amines; Analgesics; Anesthetics, Local; Cyclohexanecarboxylic Acids; Ele

2006