gamma-aminobutyric acid has been researched along with Edema-Proteinuria-Hypertension Gestosis in 11 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Gabapentin is currently FDA-approved for treating RLS and preliminary results have shown it may be effective for treating the most severe form of NVP, hyperemesis gravidarum (HG)." | 8.90 | Potential maternal symptomatic benefit of gabapentin and review of its safety in pregnancy. ( Guttuso, T; Shaman, M; Thornburg, LL, 2014) |
| " If future pregnancy registry data confirm this positive safety profile, gabapentin therapy would likely be a safe and effective treatment for RLS during pregnancy." | 6.50 | Potential maternal symptomatic benefit of gabapentin and review of its safety in pregnancy. ( Guttuso, T; Shaman, M; Thornburg, LL, 2014) |
| " Gabapentin is currently FDA-approved for treating RLS and preliminary results have shown it may be effective for treating the most severe form of NVP, hyperemesis gravidarum (HG)." | 4.90 | Potential maternal symptomatic benefit of gabapentin and review of its safety in pregnancy. ( Guttuso, T; Shaman, M; Thornburg, LL, 2014) |
| " The concentration of homocysteine in blood plasma of rats with complicated pregnancy 4." | 3.80 | GABA derivatives citrocard and salifen reduce the intensity of experimental gestosis. ( Kuznetsov, KA; Lova, VN; Reznikova, LB; Ryabukha, AF; Smirnova, LA; Suchkov, EA; Tyurenkov, IN, 2014) |
| " If future pregnancy registry data confirm this positive safety profile, gabapentin therapy would likely be a safe and effective treatment for RLS during pregnancy." | 2.50 | Potential maternal symptomatic benefit of gabapentin and review of its safety in pregnancy. ( Guttuso, T; Shaman, M; Thornburg, LL, 2014) |
| "Experimental preeclampsia was modeled by replacing the drinking water by 1." | 1.40 | [Comparative study of the effects of new neuroactive amino acid derivatives on the postnatal development of the rat's offspring with experimental preeclampsia]. ( Lebedeva, SA; Mikhailova, LI; Perfilova, VN; Tyurenkov, IN; Zhakupova, GA, 2014) |
| "It was found that the experimental preeclampsia causes a delay in physical development and maturation of sensory-motor reflexes in the offspring, as indicated by the later periods of eruption of the incisors and eye opening, response to the emergence of audio and olfactory stimuli, forming vestibular stability and coordination of movements compared to pups from females with physiological pregnancy." | 1.40 | [Comparative study of the effects of new neuroactive amino acid derivatives on the postnatal development of the rat's offspring with experimental preeclampsia]. ( Lebedeva, SA; Mikhailova, LI; Perfilova, VN; Tyurenkov, IN; Zhakupova, GA, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (72.73) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Muzyko, EA | 1 |
| Tkacheva, GA | 1 |
| Perfilova, VN | 7 |
| Matvienko, LS | 1 |
| Naumenko, LV | 1 |
| Vasil'eva, OS | 3 |
| Tyurenkov, IN | 5 |
| Popova, TA | 3 |
| Ivanova, LB | 2 |
| Prokofiev, II | 1 |
| Gulyaeva, OV | 1 |
| Stepa, LI | 1 |
| Tiurenkov, IN | 2 |
| Karamysheva, VI | 4 |
| Reznikova, LB | 3 |
| Prokof'ev, II | 1 |
| Mokrousov, IS | 2 |
| Gridin, EI | 1 |
| Mikhaĭlova, LI | 4 |
| Berestovitskaia, VM | 1 |
| Lova, VN | 1 |
| Smirnova, LA | 1 |
| Ryabukha, AF | 1 |
| Suchkov, EA | 1 |
| Kuznetsov, KA | 1 |
| Guttuso, T | 1 |
| Shaman, M | 1 |
| Thornburg, LL | 1 |
| Berestovitskaya, VM | 1 |
| Lebedeva, SA | 2 |
| Zhakupova, GA | 2 |
| Borodin, DD | 1 |
| Brophy, MH | 1 |
| Volkov, AE | 1 |
| Kuzam, LN | 1 |
| Borsheva, AA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "Determining the Effect of an Alternate Recovery Protocol Versus Current Standard of Care After Cesarean Section"[NCT03330119] | Phase 3 | 1,494 participants (Actual) | Interventional | 2017-10-04 | Terminated (stopped due to Lack of Funding/ Resident in charge graduated) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"total narcotic utilization measured with Morphine Milligram Equivalent (MME)~The conversion scale being used will be the Center for Disease Control and Prevention Morphine Equivalent Score.~Lower scores represent less opioid use and a better outcome. Higher scores represent more opioid use and a worse outcome." (NCT03330119)
Timeframe: From time of consent until hospital discharge (3 days)
| Intervention | MME (Mean) |
|---|---|
| Alternate Management | 33.3 |
| Control | 47.2 |
1 review available for gamma-aminobutyric acid and Edema-Proteinuria-Hypertension Gestosis
| Article | Year |
|---|---|
Potential maternal symptomatic benefit of gabapentin and review of its safety in pregnancy.
Topics: Amines; Anticonvulsants; Birth Weight; Congenital Abnormalities; Cyclohexanecarboxylic Acids; Female | 2014 |
10 other studies available for gamma-aminobutyric acid and Edema-Proteinuria-Hypertension Gestosis
| Article | Year |
|---|---|
Effects of Gaba Derivatives on Anxious and Compulsive Behavior in Offspring of Rats with Experimental Preeclampsia.
Topics: Animals; Animals, Outbred Strains; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Female; GABA Agon | 2020 |
Changes in oxidant and antioxidant status of females with experimental gestosis under the effect of GABA derivatives.
Topics: Animals; Female; gamma-Aminobutyric Acid; Glutathione Peroxidase; Lipid Peroxidation; Oxidative Stre | 2013 |
[Effect of GABA derivative--RSMU-151 on the development of oxidative stress in rats with experimental gestosis].
Topics: Animals; Antioxidants; Brain; Disease Models, Animal; Female; GABA Agents; gamma-Aminobutyric Acid; | 2013 |
GABA derivatives citrocard and salifen reduce the intensity of experimental gestosis.
Topics: Animals; Blood Pressure; Brain; Female; GABA Agonists; gamma-Aminobutyric Acid; Glycosaminoglycans; | 2014 |
Effect of GABA derivatives on the rate of thrombus formation, platelet aggregation, and plasma coagulation capacity in rats with experimental gestosis.
Topics: Animals; Blood Coagulation; Dipeptides; Female; gamma-Aminobutyric Acid; Glycosaminoglycans; Nicotin | 2014 |
[Gravidaprotective action of phenibut in experimental pre-eclampsia].
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Female; gamma-Aminobutyric A | 2014 |
[Comparative study of the effects of new neuroactive amino acid derivatives on the postnatal development of the rat's offspring with experimental preeclampsia].
Topics: Animals; Animals, Newborn; Behavior, Animal; Cognition; Disease Models, Animal; Female; gamma-Aminob | 2014 |
[Effect of new phenibut salts on psychic and physical development of posterity in rats with experimental gestosis].
Topics: Animals; Animals, Newborn; Behavior, Animal; Female; gamma-Aminobutyric Acid; Growth and Development | 2012 |
Zinc, preeclampsia, and gamma-aminobutyric acid.
Topics: Female; gamma-Aminobutyric Acid; Humans; Pre-Eclampsia; Pregnancy; Zinc | 1990 |
[Effect of fenibut on the fetus and newborn infant after the treatment of gestoses].
Topics: Apgar Score; Female; Fetal Monitoring; Fetus; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Pre- | 1989 |