gamma-aminobutyric acid has been researched along with Diathesis in 49 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was focused to characterize the effects of intrahippocampal application of R-verapamil, a P-glycoprotein blocker, and High Frequency Electrical Stimulation (HFS) at 130 Hz, on seizure susceptibility and extracellular concentrations of glutamate and γ-aminobutyric acid (GABA) in hippocampus of kindled rats with drug-resistant seizures." | 7.77 | Effects of high frequency electrical stimulation and R-verapamil on seizure susceptibility and glutamate and GABA release in a model of phenytoin-resistant seizures. ( Luna-Munguia, H; Orozco-Suarez, S; Rocha, L, 2011) |
| "Immature rats are more susceptible to clonic seizures induced by aminooxyacetic acid (AOAA) than mature and senile rats." | 7.68 | Age dependency of the susceptibility of rats to aminooxyacetic acid seizures. ( Cavalheiro, EA; Dziki, M; Kleinrok, Z; Parada, J; Turski, W, 1992) |
| "Intraperitoneal injection of ethanol (1-2 g/kg) and chlordiazepoxide (2-16 mg/kg) suppressed susceptibility to audiogenically induced, clonic-tonic seizures and antagonized forelimb tremor in rats undergoing ethanol withdrawal, 30 min after treatment." | 7.66 | Differential sensitivity of ethanol withdrawal signs in the rat to gamma-aminobutyric acid (GABA)mimetics: blockade of audiogenic seizures but not forelimb tremors. ( Breese, GR; Frye, GD; McCown, TJ, 1983) |
| "Bicuculline was used to investigate seizure susceptibility in pre- and peripubertal male and female rats exposed prenatally to morphine." | 5.31 | Prenatal morphine exposure alters susceptibility to bicuculline seizures in a sex- and age-specific manner. ( Schindler, CJ; Slamberová, R; Vathy, I; Velísková, J, 2000) |
| "Immature rats are more susceptible to clonic seizures induced by aminooxyacetic acid (AOAA) than mature and senile rats." | 5.28 | Age dependency of the susceptibility of rats to aminooxyacetic acid seizures. ( Cavalheiro, EA; Dziki, M; Kleinrok, Z; Parada, J; Turski, W, 1992) |
| "The present study was focused to characterize the effects of intrahippocampal application of R-verapamil, a P-glycoprotein blocker, and High Frequency Electrical Stimulation (HFS) at 130 Hz, on seizure susceptibility and extracellular concentrations of glutamate and γ-aminobutyric acid (GABA) in hippocampus of kindled rats with drug-resistant seizures." | 3.77 | Effects of high frequency electrical stimulation and R-verapamil on seizure susceptibility and glutamate and GABA release in a model of phenytoin-resistant seizures. ( Luna-Munguia, H; Orozco-Suarez, S; Rocha, L, 2011) |
| "This study aims to determine the expression of Gamma-aminobutyric acid (GABA) following hypoxia in neonatal rats and explore how it may increase susceptibility to epilepsy later in life." | 3.77 | Downregulation of hippocampal GABA after hypoxia-induced seizures in neonatal rats. ( Li, K; Sun, W; Wang, Y; Xu, E; Xu, ZC; Zeng, W; Zhan, L, 2011) |
| "The effects of valproate on CNS concentrations of gamma-aminobutyric acid (GABA), glulamate (GLU), glutamine (GLN); dopamine (DA), serotonin (5-HT), and metabolites were examined in tissue extracts of caudate nucleus of genetic substrains of Balb/c mice susceptible (EP) or resistant (ER) to audiogenic seizures." | 3.69 | Effects of valproate on amino acid and monoamine concentrations in striatum of audiogenic seizure-prone Balb/c mice. ( Alexiuk, NA; Vriend, JP, 1996) |
| "Immature rats are more susceptible to clonic seizures induced by aminooxyacetic acid (AOAA) than mature and senile rats." | 3.68 | Age dependency of the susceptibility of rats to aminooxyacetic acid seizures. ( Cavalheiro, EA; Dziki, M; Kleinrok, Z; Parada, J; Turski, W, 1992) |
| "Intraperitoneal injection of ethanol (1-2 g/kg) and chlordiazepoxide (2-16 mg/kg) suppressed susceptibility to audiogenically induced, clonic-tonic seizures and antagonized forelimb tremor in rats undergoing ethanol withdrawal, 30 min after treatment." | 3.66 | Differential sensitivity of ethanol withdrawal signs in the rat to gamma-aminobutyric acid (GABA)mimetics: blockade of audiogenic seizures but not forelimb tremors. ( Breese, GR; Frye, GD; McCown, TJ, 1983) |
| "Epilepsy is characterized by recurrent seizures due to abnormal hyperexcitation of neurons." | 2.72 | The Role of Phospholipase C in GABAergic Inhibition and Its Relevance to Epilepsy. ( Kim, HY; Kim, JI; Suh, PG, 2021) |
| "Epilepsy or seizure disorder is one of the most common neurological diseases in humans." | 2.48 | Methylmercury: a potential environmental risk factor contributing to epileptogenesis. ( Yuan, Y, 2012) |
| "Testosterone levels in PTSD patients differed neither from that observed in PTSD resistant nor control groups." | 1.72 | Biomarkers in PTSD-susceptible and resistant veterans with war experience of more than ten years ago: FOCUS ON cortisol, thyroid hormones, testosterone and GABA. ( Boks, MP; Chipeeva, N; de Kloet, ER; Feklicheva, I; Komelkova, M; Korobova, S; Kuznetsova, Y; Mamonova, M; Maslennikova, E; Pashkov, A; Platkovski, P; Sidorenko, O; Tseilikman, O; Tseilikman, V; Vasilenko, T, 2022) |
| "elegans allows our electroconvulsive seizure (ES) assay to be used as a behavioral readout of the locomotor circuit and neuronal function." | 1.62 | O-GlcNAc transferase OGT-1 and the ubiquitin ligase EEL-1 modulate seizure susceptibility in C. elegans. ( Dawson-Scully, K; Giles, A; Grill, B; Opperman, KJ; Suthakaran, N; Wiggins, J, 2021) |
| "Gamma-aminobutyric acid was significantly upregulated in susceptible group but downregulated in resilient group." | 1.62 | Alterations of neurotransmitters and related metabolites in the habenula from CUMS-susceptible and -resilient rats. ( Bai, M; Chen, C; Chen, X; Chen, Z; Cheng, K; He, Y; Lan, T; Li, Y; Tian, Y; Wang, Y; Wu, Z; Xie, P; Yu, H, 2021) |
| "Complex febrile seizures (FSs) lead to a high risk of intractable temporal lobe epilepsy during adulthood, yet the pathological process of complex FSs is largely unknown." | 1.56 | Microglial Displacement of GABAergic Synapses Is a Protective Event during Complex Febrile Seizures. ( Chen, Z; Dai, H; Feng, B; Hu, W; Shi, P; Trapp, BD; Wan, Y; Xu, C; You, Y; Yu, J, 2020) |
| " Results of the study indicate that 1) Early SIS could be considered as an animal model of psychosocial stress to investigate the psychiatric comorbidities in seizure disorders, 2) Chronic administration of low dose GBP prevented the shaping of behavioral abnormalities in adulthood, 3) Chronic administration of low dose GBP produced no negative behavioral effects in socially conditioned mice suggesting the safety of the drug, 4) Gabapentin at low doses may be considered as an agent for management of epilepsy in individuals with psychiatric comorbidities." | 1.46 | Protective effects of gabapentin against the seizure susceptibility and comorbid behavioral abnormalities in the early socially isolated mice. ( Amini-Khoei, H; Amiri, S; Ghazi-Khansari, M; Haj-Mirzaian, A; Mohsenzadeh, A; Olson, CO; Rahimi-Balaei, M; Rastegar, M; Razmi, A; Shirzadian, A; Zarrindast, MR, 2017) |
| "Using a rat model of complex febrile seizures, which are thought to be a precipitating insult of TLE later in life, we report that aberrant migration of neonatal-generated granule cells results in granule cell ectopia that persists into adulthood." | 1.38 | GABAergic excitation after febrile seizures induces ectopic granule cells and adult epilepsy. ( Ichikawa, J; Ikegaya, Y; Koyama, R; Matsuki, N; Miyamoto, D; Muramatsu, R; Sasaki, T; Tao, K, 2012) |
| "We show that kcc(DHS1) seizure sensitivity in MB neurons acts via a weakening of chemical synaptic inhibition by GABAergic transmission and suggest that this is due to disruption of intracellular Cl(-) gradients in MB neurons." | 1.36 | Seizure sensitivity is ameliorated by targeted expression of K+-Cl- cotransporter function in the mushroom body of the Drosophila brain. ( Fajilan, AA; Hekmat-Scafe, DS; Hsu, R; Lee, AW; Mercado, A; Mount, DB; Tanouye, MA, 2010) |
| "FGF22-deficient mice are resistant to epileptic seizures, and FGF7-deficient mice are prone to them, as expected from the alterations in excitatory/inhibitory balance." | 1.36 | Distinct FGFs promote differentiation of excitatory and inhibitory synapses. ( Javed, D; Johnson-Venkatesh, EM; Sutton, MA; Terauchi, A; Toth, AB; Umemori, H, 2010) |
| "The heightened susceptibility to seizures appears to be due, at least in part, to developmental changes that skew the balance between excitatory and inhibitory neurotransmitter systems in the brain in favor of a state of excitation." | 1.33 | Rearranging receptors. ( Brooks-Kayal, AR, 2005) |
| "The immature brain is prone to seizures but the underlying mechanisms are poorly understood." | 1.32 | Developmental changes in GABAergic actions and seizure susceptibility in the rat hippocampus. ( Ben-Ari, Y; Holmes, GL; Khalilov, I; Khazipov, R; Morozova, E; Tyzio, R, 2004) |
| "Bicuculline was used to investigate seizure susceptibility in pre- and peripubertal male and female rats exposed prenatally to morphine." | 1.31 | Prenatal morphine exposure alters susceptibility to bicuculline seizures in a sex- and age-specific manner. ( Schindler, CJ; Slamberová, R; Vathy, I; Velísková, J, 2000) |
| "Kindled seizures were produced on day 16 of life by repeatedly applying an electrical current stimulus to the amygdala electrode." | 1.31 | Anticonvulsant efficacy of gabapentin on kindling in the immature brain. ( Lado, FA; Moshé, SL; Sperber, EF, 2001) |
| "Susceptibility to audiogenic seizures (AGS) was investigated in Sprague-Dawley rats subjected to cardiac arrest cerebral ischemia (CACI), produced by compression of the major cardiac vessels." | 1.29 | Development of susceptibility to audiogenic seizures following cardiac arrest cerebral ischemia in rats. ( Kawahara, N; Kawai, K; Klatzo, I; Penix, LP; Ruetzler, CA, 1995) |
| " Generalized tonic-clonic seizures observed in EP mice were inhibited by valproate, administered 1 h prior to testing, in a dose-response fashion." | 1.29 | Effects of valproate on amino acid and monoamine concentrations in striatum of audiogenic seizure-prone Balb/c mice. ( Alexiuk, NA; Vriend, JP, 1996) |
| "Generalized tonic-clonic seizures observed in EP mice were inhibited by valproate, administered 1 h prior to testing, in a dose-response fashion." | 1.29 | Effects of valproate on amino acid and monoamine concentrations in striatum of audiogenic seizure-prone Balb/c mice. ( Alexiuk, NA; Vriend, JP, 1996) |
| "Immature rats are more susceptible to clonic seizures induced by aminooxyacetic acid (AOAA) than mature and senile rats." | 1.28 | Age dependency of the susceptibility of rats to aminooxyacetic acid seizures. ( Cavalheiro, EA; Dziki, M; Kleinrok, Z; Parada, J; Turski, W, 1992) |
| "Utilizing audiogenic seizure-prone P77PMC rats, the effects of cholecystokinin octapeptide (CCK-8) on genetic seizure susceptibility were studied in vivo, in cerebral cortical synaptosomes, and in cortical neuronal cell cultures." | 1.28 | Effects of cholecystokinin octapeptide on genetically determined seizure susceptibility. ( Lin, PX; Wu, XR, 1992) |
| "Thus, the seizure-facilitating nigral efferents may be subject to inhibition by both GABA and opiates and may normally be driven by substance P." | 1.27 | Role of the substantia nigra in GABA-mediated anticonvulsant actions. ( Gale, K, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (12.24) | 18.7374 |
| 1990's | 10 (20.41) | 18.2507 |
| 2000's | 10 (20.41) | 29.6817 |
| 2010's | 14 (28.57) | 24.3611 |
| 2020's | 9 (18.37) | 2.80 |
| Authors | Studies |
|---|---|
| Suthakaran, N | 1 |
| Wiggins, J | 1 |
| Giles, A | 1 |
| Opperman, KJ | 1 |
| Grill, B | 1 |
| Dawson-Scully, K | 1 |
| Feklicheva, I | 1 |
| Boks, MP | 1 |
| de Kloet, ER | 1 |
| Chipeeva, N | 1 |
| Maslennikova, E | 1 |
| Pashkov, A | 1 |
| Korobova, S | 1 |
| Komelkova, M | 1 |
| Kuznetsova, Y | 1 |
| Platkovski, P | 1 |
| Mamonova, M | 1 |
| Sidorenko, O | 1 |
| Vasilenko, T | 1 |
| Tseilikman, O | 1 |
| Tseilikman, V | 1 |
| Liu, X | 1 |
| van Beek, N | 1 |
| Cepic, A | 1 |
| Andreani, NA | 1 |
| Chung, CJ | 1 |
| Hermes, BM | 1 |
| Yilmaz, K | 1 |
| Benoit, S | 1 |
| Drenovska, K | 1 |
| Gerdes, S | 1 |
| Gläser, R | 1 |
| Goebeler, M | 1 |
| Günther, C | 1 |
| von Georg, A | 1 |
| Hammers, CM | 1 |
| Holtsche, MM | 1 |
| Hübner, F | 1 |
| Kiritsi, D | 1 |
| Schauer, F | 1 |
| Linnenmann, B | 1 |
| Huilaja, L | 1 |
| Tasanen-Määttä, K | 1 |
| Vassileva, S | 1 |
| Zillikens, D | 1 |
| Sadik, CD | 1 |
| Schmidt, E | 1 |
| Ibrahim, S | 1 |
| Baines, JF | 1 |
| Sun, MY | 1 |
| Ziolkowski, L | 1 |
| Lambert, P | 1 |
| Shu, HJ | 1 |
| Keiser, M | 1 |
| Rensing, N | 1 |
| Warikoo, N | 1 |
| Martinek, M | 1 |
| Platnick, C | 1 |
| Benz, A | 1 |
| Bracamontes, J | 1 |
| Akk, G | 1 |
| Steinbach, JH | 1 |
| Zorumski, CF | 1 |
| Wong, M | 1 |
| Mennerick, S | 1 |
| Fukuyama, K | 1 |
| Fukuzawa, M | 1 |
| Shiroyama, T | 1 |
| Okada, M | 1 |
| Khom, S | 1 |
| Steinkellner, T | 1 |
| Hnasko, TS | 1 |
| Roberto, M | 1 |
| Wan, Y | 1 |
| Feng, B | 1 |
| You, Y | 1 |
| Yu, J | 1 |
| Xu, C | 1 |
| Dai, H | 1 |
| Trapp, BD | 1 |
| Shi, P | 1 |
| Chen, Z | 3 |
| Hu, W | 1 |
| Tian, Y | 1 |
| Wu, Z | 1 |
| Wang, Y | 3 |
| Chen, C | 1 |
| He, Y | 1 |
| Lan, T | 1 |
| Li, Y | 2 |
| Bai, M | 1 |
| Yu, H | 2 |
| Chen, X | 1 |
| Cheng, K | 1 |
| Xie, P | 1 |
| Kim, HY | 1 |
| Suh, PG | 1 |
| Kim, JI | 1 |
| Ren, E | 1 |
| Curia, G | 1 |
| Baizabal-Carvallo, JF | 1 |
| Li, X | 1 |
| Qin, L | 1 |
| Zhang, Z | 1 |
| Tao, C | 1 |
| Liu, Y | 1 |
| Xue, Y | 1 |
| Zhang, X | 1 |
| Xu, Z | 1 |
| Lou, H | 1 |
| Tan, Z | 1 |
| Saftig, P | 1 |
| Xu, T | 1 |
| Bi, G | 1 |
| Duan, S | 1 |
| Gao, Z | 1 |
| Petruccelli, E | 1 |
| Lansdon, P | 1 |
| Kitamoto, T | 1 |
| Amiri, S | 1 |
| Haj-Mirzaian, A | 1 |
| Amini-Khoei, H | 1 |
| Razmi, A | 1 |
| Shirzadian, A | 1 |
| Rahimi-Balaei, M | 1 |
| Olson, CO | 1 |
| Mohsenzadeh, A | 1 |
| Rastegar, M | 1 |
| Zarrindast, MR | 1 |
| Ghazi-Khansari, M | 1 |
| Bae, MH | 1 |
| Bissonette, GB | 1 |
| Mars, WM | 1 |
| Michalopoulos, GK | 1 |
| Achim, CL | 1 |
| Depireux, DA | 1 |
| Powell, EM | 1 |
| Hekmat-Scafe, DS | 1 |
| Mercado, A | 1 |
| Fajilan, AA | 1 |
| Lee, AW | 1 |
| Hsu, R | 1 |
| Mount, DB | 1 |
| Tanouye, MA | 1 |
| Terauchi, A | 1 |
| Johnson-Venkatesh, EM | 1 |
| Toth, AB | 1 |
| Javed, D | 1 |
| Sutton, MA | 1 |
| Umemori, H | 1 |
| Luna-Munguia, H | 1 |
| Orozco-Suarez, S | 1 |
| Rocha, L | 1 |
| Zhan, L | 1 |
| Zeng, W | 1 |
| Li, K | 1 |
| Sun, W | 1 |
| Xu, ZC | 1 |
| Xu, E | 1 |
| Yuan, Y | 1 |
| Kim, JY | 1 |
| Liu, CY | 1 |
| Zhang, F | 1 |
| Duan, X | 1 |
| Wen, Z | 1 |
| Song, J | 1 |
| Feighery, E | 1 |
| Lu, B | 1 |
| Rujescu, D | 1 |
| St Clair, D | 1 |
| Christian, K | 1 |
| Callicott, JH | 1 |
| Weinberger, DR | 1 |
| Song, H | 1 |
| Ming, GL | 1 |
| Portelli, J | 1 |
| Thielemans, L | 1 |
| Ver Donck, L | 1 |
| Loyens, E | 1 |
| Coppens, J | 1 |
| Aourz, N | 1 |
| Aerssens, J | 1 |
| Vermoesen, K | 1 |
| Clinckers, R | 1 |
| Schallier, A | 1 |
| Michotte, Y | 1 |
| Moechars, D | 1 |
| Collingridge, GL | 1 |
| Bortolotto, ZA | 1 |
| Smolders, I | 1 |
| Koyama, R | 1 |
| Tao, K | 1 |
| Sasaki, T | 1 |
| Ichikawa, J | 1 |
| Miyamoto, D | 1 |
| Muramatsu, R | 1 |
| Matsuki, N | 1 |
| Ikegaya, Y | 1 |
| Takeda, A | 1 |
| Hirate, M | 1 |
| Tamano, H | 1 |
| Nisibaba, D | 1 |
| Oku, N | 1 |
| BAXTER, CF | 1 |
| ROBERTS, E | 1 |
| EIDELBERG, E | 1 |
| Khazipov, R | 1 |
| Khalilov, I | 1 |
| Tyzio, R | 1 |
| Morozova, E | 1 |
| Ben-Ari, Y | 1 |
| Holmes, GL | 1 |
| Brooks-Kayal, AR | 1 |
| Locke, CJ | 1 |
| Williams, SN | 1 |
| Schwarz, EM | 1 |
| Caldwell, GA | 1 |
| Caldwell, KA | 1 |
| Frye, GD | 1 |
| McCown, TJ | 1 |
| Breese, GR | 1 |
| Ribak, CE | 1 |
| Morin, CL | 1 |
| Faingold, CL | 2 |
| Riaz, A | 1 |
| Kawai, K | 1 |
| Penix, LP | 1 |
| Kawahara, N | 1 |
| Ruetzler, CA | 1 |
| Klatzo, I | 1 |
| Gould, EM | 1 |
| Curto, KA | 1 |
| Craig, CR | 1 |
| Fleming, WW | 1 |
| Taylor, DA | 1 |
| Vriend, JP | 1 |
| Alexiuk, NA | 1 |
| Schindler, CJ | 2 |
| Velísková, J | 2 |
| Slamberová, R | 2 |
| Vathy, I | 2 |
| Lado, FA | 1 |
| Sperber, EF | 1 |
| Moshé, SL | 3 |
| Yang, L | 1 |
| Long, C | 1 |
| Santer, RM | 1 |
| Dering, MA | 1 |
| Ranson, RN | 1 |
| Waboso, HN | 1 |
| Watson, AH | 1 |
| Turski, W | 1 |
| Dziki, M | 1 |
| Parada, J | 1 |
| Kleinrok, Z | 1 |
| Cavalheiro, EA | 1 |
| Wu, XR | 1 |
| Lin, PX | 1 |
| Arias, C | 1 |
| Valero, H | 1 |
| Tapia, R | 1 |
| Sieklucka, M | 1 |
| Bortolotto, Z | 1 |
| Heim, C | 1 |
| Block, F | 1 |
| Sontag, KH | 1 |
| Nakamura, J | 1 |
| Mine, K | 1 |
| Yamada, S | 1 |
| Cocchi, R | 1 |
| Okada, R | 1 |
| Albala, BJ | 1 |
| Gale, K | 1 |
| Olsen, RW | 1 |
| Wamsley, JK | 1 |
| Lee, RJ | 1 |
| Lomax, P | 1 |
6 reviews available for gamma-aminobutyric acid and Diathesis
| Article | Year |
|---|---|
The Role of Phospholipase C in GABAergic Inhibition and Its Relevance to Epilepsy.
Topics: Animals; Anticonvulsants; Biomarkers; Disease Susceptibility; Epilepsy; GABA Antagonists; gamma-Amin | 2021 |
Synaptic Reshaping and Neuronal Outcomes in the Temporal Lobe Epilepsy.
Topics: Animals; Astrocytes; Disease Susceptibility; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Gluta | 2021 |
The neurological syndromes associated with glutamic acid decarboxylase antibodies.
Topics: Autoantibodies; Autoimmune Diseases; Autoimmunity; Brain; Combined Modality Therapy; Disease Suscept | 2019 |
Methylmercury: a potential environmental risk factor contributing to epileptogenesis.
Topics: Animals; Disease Models, Animal; Disease Susceptibility; Environmental Exposure; Epilepsy; gamma-Ami | 2012 |
The role of the inferior colliculus in a genetic model of audiogenic seizures.
Topics: Acoustic Stimulation; Animals; Disease Models, Animal; Disease Susceptibility; Epilepsy; gamma-Amino | 1995 |
Benzodiazepine/barbiturate/GABA receptor-chloride ionophore complex in a genetic model for generalized epilepsy.
Topics: Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Binding Sites; Chlorides; Disease Models, A | 1986 |
43 other studies available for gamma-aminobutyric acid and Diathesis
| Article | Year |
|---|---|
O-GlcNAc transferase OGT-1 and the ubiquitin ligase EEL-1 modulate seizure susceptibility in C. elegans.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Susceptibility; GABAergic | 2021 |
Biomarkers in PTSD-susceptible and resistant veterans with war experience of more than ten years ago: FOCUS ON cortisol, thyroid hormones, testosterone and GABA.
Topics: Biomarkers; Disease Susceptibility; gamma-Aminobutyric Acid; Humans; Hydrocortisone; Stress Disorder | 2022 |
The gut microbiome in bullous pemphigoid: implications of the gut-skin axis for disease susceptibility.
Topics: Aged; Disease Susceptibility; gamma-Aminobutyric Acid; Gastrointestinal Microbiome; Humans; Pemphigo | 2023 |
Mild chronic perturbation of inhibition severely alters hippocampal function.
Topics: Animals; Biomarkers; Cell Line; Diazepam; Disease Susceptibility; Electroencephalography; Excitatory | 2019 |
Pathomechanism of nocturnal paroxysmal dystonia in autosomal dominant sleep-related hypermotor epilepsy with S284L-mutant α4 subunit of nicotinic ACh receptor.
Topics: Alleles; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Substitution; Animals; | 2020 |
Alcohol dependence potentiates substance P/neurokinin-1 receptor signaling in the rat central nucleus of amygdala.
Topics: Adaptation, Physiological; Alcoholism; Animals; Central Amygdaloid Nucleus; Disease Models, Animal; | 2020 |
Microglial Displacement of GABAergic Synapses Is a Protective Event during Complex Febrile Seizures.
Topics: Animals; Cerebral Cortex; Disease Susceptibility; gamma-Aminobutyric Acid; Imaging, Three-Dimensiona | 2020 |
Alterations of neurotransmitters and related metabolites in the habenula from CUMS-susceptible and -resilient rats.
Topics: Animals; Depression; Disease Susceptibility; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Haben | 2021 |
Presynaptic Endosomal Cathepsin D Regulates the Biogenesis of GABAergic Synaptic Vesicles.
Topics: Adolescent; Aged; Animals; Cathepsin D; Disease Susceptibility; Endocytosis; Endosomes; gamma-Aminob | 2019 |
Exaggerated Nighttime Sleep and Defective Sleep Homeostasis in a Drosophila Knock-In Model of Human Epilepsy.
Topics: Animals; Animals, Genetically Modified; Circadian Rhythm; Disease Models, Animal; Disease Susceptibi | 2015 |
Protective effects of gabapentin against the seizure susceptibility and comorbid behavioral abnormalities in the early socially isolated mice.
Topics: Aggression; Amines; Animals; Anticonvulsants; Anxiety; Behavior, Animal; Comorbidity; Cyclohexanecar | 2017 |
Hepatocyte growth factor (HGF) modulates GABAergic inhibition and seizure susceptibility.
Topics: Action Potentials; Analysis of Variance; Animals; Animals, Genetically Modified; Animals, Newborn; A | 2010 |
Seizure sensitivity is ameliorated by targeted expression of K+-Cl- cotransporter function in the mushroom body of the Drosophila brain.
Topics: Animals; Behavior, Animal; Brain; Disease Susceptibility; Drosophila melanogaster; Electrophysiologi | 2010 |
Distinct FGFs promote differentiation of excitatory and inhibitory synapses.
Topics: Animals; Cell Differentiation; Cells, Cultured; Dendrites; Disease Susceptibility; Epilepsy; Excitat | 2010 |
Effects of high frequency electrical stimulation and R-verapamil on seizure susceptibility and glutamate and GABA release in a model of phenytoin-resistant seizures.
Topics: Animals; Disease Models, Animal; Disease Susceptibility; Drug Resistance; Electric Stimulation; Extr | 2011 |
Downregulation of hippocampal GABA after hypoxia-induced seizures in neonatal rats.
Topics: Animals; Animals, Newborn; Disease Susceptibility; Down-Regulation; Epilepsy; gamma-Aminobutyric Aci | 2011 |
Interplay between DISC1 and GABA signaling regulates neurogenesis in mice and risk for schizophrenia.
Topics: Animals; Dendrites; Disease Susceptibility; Female; gamma-Aminobutyric Acid; Mice; Mice, Inbred C57B | 2012 |
Inactivation of the constitutively active ghrelin receptor attenuates limbic seizure activity in rodents.
Topics: Analysis of Variance; Animals; Anticonvulsants; Calcium; Disease Models, Animal; Disease Susceptibil | 2012 |
GABAergic excitation after febrile seizures induces ectopic granule cells and adult epilepsy.
Topics: Animals; Animals, Suckling; Brain Diseases; Bumetanide; Cell Lineage; Cell Movement; Choristoma; Den | 2012 |
Susceptibility to kainate-induced seizures under dietary zinc deficiency.
Topics: Animals; Brain; Brain Chemistry; Deficiency Diseases; Disease Susceptibility; Dose-Response Relation | 2003 |
gamma-Aminobutyric acid and seizure susceptibility in area of normal cat brain cortex.
Topics: Amino Acids; Animals; Brain; Cats; Cerebral Cortex; Disease Susceptibility; gamma-Aminobutyric Acid; | 1960 |
Developmental changes in GABAergic actions and seizure susceptibility in the rat hippocampus.
Topics: Aging; Animals; Animals, Newborn; Bicuculline; Disease Susceptibility; Excitatory Postsynaptic Poten | 2004 |
Rearranging receptors.
Topics: Animals; Brain; Cerebellum; Child, Preschool; Disease Models, Animal; Disease Susceptibility; Epilep | 2005 |
Genetic interactions among cortical malformation genes that influence susceptibility to convulsions in C. elegans.
Topics: Animals; Animals, Genetically Modified; Behavior, Animal; Caenorhabditis elegans; Caenorhabditis ele | 2006 |
Differential sensitivity of ethanol withdrawal signs in the rat to gamma-aminobutyric acid (GABA)mimetics: blockade of audiogenic seizures but not forelimb tremors.
Topics: 4-Aminobutyrate Transaminase; Acoustic Stimulation; Aminobutyrates; Animals; Chlordiazepoxide; Disea | 1983 |
Ethanol withdrawal induces increased firing in inferior colliculus neurons associated with audiogenic seizure susceptibility.
Topics: Acoustic Stimulation; Animals; Behavior, Animal; Disease Susceptibility; Ethanol; gamma-Aminobutyric | 1995 |
Development of susceptibility to audiogenic seizures following cardiac arrest cerebral ischemia in rats.
Topics: Acoustic Stimulation; Animals; Brain Ischemia; Disease Susceptibility; gamma-Aminobutyric Acid; Glut | 1995 |
The role of GABAA receptors in the subsensitivity of Purkinje neurons to GABA in genetic epilepsy prone rats.
Topics: Animals; Disease Susceptibility; Epilepsy; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Purkin | 1995 |
Effects of valproate on amino acid and monoamine concentrations in striatum of audiogenic seizure-prone Balb/c mice.
Topics: Acoustic Stimulation; Amino Acids; Animals; Anticonvulsants; Biogenic Monoamines; Corpus Striatum; D | 1996 |
Prenatal morphine exposure alters susceptibility to bicuculline seizures in a sex- and age-specific manner.
Topics: Age Factors; Analgesics, Opioid; Animals; Bicuculline; Convulsants; Disease Susceptibility; Epilepsy | 2000 |
Anticonvulsant efficacy of gabapentin on kindling in the immature brain.
Topics: Acetates; Age Factors; Amines; Amygdala; Animals; Anticonvulsants; Behavior, Animal; Brain; Child; C | 2001 |
Audiogenic seizure susceptibility is induced by termination of continuous infusion of gamma-aminobutyric acid or an N-methyl-D-aspartic acid Antagonist into the inferior colliculus.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Animals; Behavior, Animal; Catheterization; Disea | 2001 |
Sexual dimorphism and developmental regulation of substantia nigra function.
Topics: Aging; Animals; Animals, Newborn; Castration; Convulsants; Disease Susceptibility; Female; GABA Agon | 2001 |
Prenatal morphine exposure decreases susceptibility of adult male rat offspring to bicuculline seizures.
Topics: Animals; Bicuculline; Brain; Disease Susceptibility; Epilepsy; Female; GABA Antagonists; gamma-Amino | 2001 |
Differential susceptibility to ageing of rat preganglionic neurones projecting to the major pelvic ganglion and of their afferent inputs.
Topics: Afferent Pathways; Aging; Animals; Dendrites; Disease Susceptibility; Efferent Pathways; gamma-Amino | 2002 |
Age dependency of the susceptibility of rats to aminooxyacetic acid seizures.
Topics: Aging; Aminooxyacetic Acid; Animals; Anticonvulsants; Body Temperature; Brain; Carbamazepine; Clonaz | 1992 |
Effects of cholecystokinin octapeptide on genetically determined seizure susceptibility.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Disease Susceptibility; gamma-Aminobutyric Acid; Injectio | 1992 |
Inhibition of brain glutamate decarboxylase activity is related to febrile seizures in rat pups.
Topics: Animals; Animals, Newborn; Brain; Chromatography, High Pressure Liquid; Disease Susceptibility; gamm | 1992 |
Decreased susceptibility to seizures induced by bicuculline after transient bilateral clamping of the carotid arteries in rats.
Topics: Animals; Bicuculline; Brain Chemistry; Carotid Arteries; Constriction; Disease Susceptibility; Femal | 1991 |
Effects of anticonvulsants on the electroconvulsive threshold lowered by DA, 5-HT or GABA depletion.
Topics: Animals; Anticonvulsants; Disease Susceptibility; Dopamine; Electroshock; gamma-Aminobutyric Acid; M | 1990 |
Reduction of susceptibility to upper respiratory tract infections in Down syndrome children following treatment with GABAergic drugs: report of 70 cases.
Topics: Benzodiazepines; Child; Disease Susceptibility; Down Syndrome; Female; gamma-Aminobutyric Acid; Glut | 1987 |
Ventromedial thalamic lesions and seizure susceptibility.
Topics: Animals; Disease Susceptibility; Flurothyl; gamma-Aminobutyric Acid; Male; Neural Pathways; Rats; Ra | 1985 |
Role of the substantia nigra in GABA-mediated anticonvulsant actions.
Topics: Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Brain Diseases; Denervation; D | 1986 |