gamma-aminobutyric acid has been researched along with Diarrhea in 6 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effects of gabapentin on sensory and motor function of the rectum in patients with diarrhoea-predominant irritable bowel syndrome." | 9.11 | Gabapentin reduces rectal mechanosensitivity and increases rectal compliance in patients with diarrhoea-predominant irritable bowel syndrome. ( Cho, SW; Kim, JH; Lee, KJ, 2005) |
| "Our results show that gabapentin reduces rectal sensory thresholds through attenuating rectal sensitivity to distension and enhancing rectal compliance in diarrhoea-predominant irritable bowel syndrome patients." | 9.11 | Gabapentin reduces rectal mechanosensitivity and increases rectal compliance in patients with diarrhoea-predominant irritable bowel syndrome. ( Cho, SW; Kim, JH; Lee, KJ, 2005) |
| "Gabapentin has been shown to reduce elements of central sensitization in human experimental hyperalgesia." | 6.71 | Gabapentin reduces rectal mechanosensitivity and increases rectal compliance in patients with diarrhoea-predominant irritable bowel syndrome. ( Cho, SW; Kim, JH; Lee, KJ, 2005) |
| "To evaluate the effects of gabapentin on sensory and motor function of the rectum in patients with diarrhoea-predominant irritable bowel syndrome." | 5.11 | Gabapentin reduces rectal mechanosensitivity and increases rectal compliance in patients with diarrhoea-predominant irritable bowel syndrome. ( Cho, SW; Kim, JH; Lee, KJ, 2005) |
| "Our results show that gabapentin reduces rectal sensory thresholds through attenuating rectal sensitivity to distension and enhancing rectal compliance in diarrhoea-predominant irritable bowel syndrome patients." | 5.11 | Gabapentin reduces rectal mechanosensitivity and increases rectal compliance in patients with diarrhoea-predominant irritable bowel syndrome. ( Cho, SW; Kim, JH; Lee, KJ, 2005) |
| "Fifty patients with refractory partial seizures took part in a prospective, observational study of adjuvant gabapentin (GBP) in increasing doses." | 5.08 | High dose gabapentin in refractory partial epilepsy: clinical observations in 50 patients. ( Brodie, MJ; Forrest, G; Sills, GJ; Wilson, EA, 1998) |
| "Gabapentin has been shown to reduce elements of central sensitization in human experimental hyperalgesia." | 2.71 | Gabapentin reduces rectal mechanosensitivity and increases rectal compliance in patients with diarrhoea-predominant irritable bowel syndrome. ( Cho, SW; Kim, JH; Lee, KJ, 2005) |
| " In six patients, including three taking 6000 mg daily, GBP concentrations continued to rise linearly at each dosage increment." | 2.69 | High dose gabapentin in refractory partial epilepsy: clinical observations in 50 patients. ( Brodie, MJ; Forrest, G; Sills, GJ; Wilson, EA, 1998) |
| "Fifty patients with refractory partial seizures took part in a prospective, observational study of adjuvant gabapentin (GBP) in increasing doses." | 2.69 | High dose gabapentin in refractory partial epilepsy: clinical observations in 50 patients. ( Brodie, MJ; Forrest, G; Sills, GJ; Wilson, EA, 1998) |
| "The fecal microbiota during IBS symptom exacerbation exhibited significant differences in the phylogenic pattern and short-chain fatty acid compared with fecal samples during defecation when symptoms were not exacerbated." | 1.72 | Omics profiles of fecal and oral microbiota change in irritable bowel syndrome patients with diarrhea and symptom exacerbation. ( Fukuda, S; Fukudo, S; Gotoh, Y; Hayashi, T; Kasahara, Y; Kawashima, J; Kurokawa, K; Mori, H; Nakamura, K; Sato, Y; Tanaka, Y; Yamashita, R, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Tanaka, Y | 1 |
| Yamashita, R | 1 |
| Kawashima, J | 1 |
| Mori, H | 1 |
| Kurokawa, K | 1 |
| Fukuda, S | 1 |
| Gotoh, Y | 1 |
| Nakamura, K | 1 |
| Hayashi, T | 1 |
| Kasahara, Y | 1 |
| Sato, Y | 1 |
| Fukudo, S | 1 |
| Zhang, M | 1 |
| Zheng, Y | 1 |
| Li, X | 1 |
| Wu, H | 1 |
| Liu, P | 1 |
| Zhang, K | 1 |
| Shi, Z | 1 |
| Lv, M | 1 |
| Wang, F | 1 |
| Tang, X | 1 |
| Li, Y | 1 |
| Xiang, YY | 1 |
| Lu, WY | 1 |
| Liu, C | 1 |
| Li, J | 1 |
| Lee, KJ | 1 |
| Kim, JH | 1 |
| Cho, SW | 1 |
| Mohammadi, M | 1 |
| Ghani, E | 1 |
| Ghasemi, A | 1 |
| Khoshbaten, A | 1 |
| Asgari, A | 1 |
| Wilson, EA | 1 |
| Sills, GJ | 1 |
| Forrest, G | 1 |
| Brodie, MJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Gabapentin Treatment of Postural Tachycardia Syndrome (PoTS): a Pilot Study[NCT04345432] | 10 participants (Actual) | Interventional | 2014-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for gamma-aminobutyric acid and Diarrhea
| Article | Year |
|---|---|
Gabapentin reduces rectal mechanosensitivity and increases rectal compliance in patients with diarrhoea-predominant irritable bowel syndrome.
Topics: Adult; Amines; Analgesics; Compliance; Cyclohexanecarboxylic Acids; Diarrhea; Double-Blind Method; G | 2005 |
High dose gabapentin in refractory partial epilepsy: clinical observations in 50 patients.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Diarrhea; D | 1998 |
4 other studies available for gamma-aminobutyric acid and Diarrhea
| Article | Year |
|---|---|
Omics profiles of fecal and oral microbiota change in irritable bowel syndrome patients with diarrhea and symptom exacerbation.
Topics: Butyrates; Diarrhea; Fatty Acids, Volatile; Feces; gamma-Aminobutyric Acid; Glutamine; Humans; Hydro | 2022 |
Tong-Xie-Yao-Fang alleviates diarrhea-predominant irritable bowel syndrome in rats via the GCN2/PERK-eIF2α-ATF4 signaling pathway.
Topics: Activating Transcription Factor 4; Animals; Body Weight; Caspase 3; Cysteine; Diarrhea; Drugs, Chine | 2022 |
A novel role of intestine epithelial GABAergic signaling in regulating intestinal fluid secretion.
Topics: Adult; Animals; Autocrine Communication; Blotting, Western; Cell Line; Diarrhea; Disease Models, Ani | 2012 |
Synaptosomal GABA uptake decreases in paraoxon-treated rat brain.
Topics: Acetylcholinesterase; Animals; beta-Alanine; Brain; Cerebral Cortex; Cholinesterase Inhibitors; Diar | 2008 |