gamma-aminobutyric acid has been researched along with Diabetic Retinopathy in 13 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to investigate whether taurine ameliorate the diabetic retinopathy, and to further explore the underlying mechanisms." | 7.74 | Dietary taurine supplementation ameliorates diabetic retinopathy via anti-excitotoxicity of glutamate in streptozotocin-induced Sprague-Dawley rats. ( Chen, F; Chen, K; Mi, M; Tang, Y; Wang, J; Wei, N; Xu, H; Xu, Z; Yu, X; Zeng, K; Zhang, Q; Zhu, J, 2008) |
| "To study the levels of glutamate and gamma-aminobutyric acid (GABA) in vitreous of patients with proliferative diabetic retinopathy (PDR) and to investigate their roles in retinal ischemia." | 7.70 | Detection of glutamate and gamma-aminobutyric acid in vitreous of patients with proliferative diabetic retinopathy. ( Deng, J; Gao, R; Wu, DZ, 2000) |
| "Charles Bonnet syndrome is a condition characterised by the presence of visual hallucinations in patients having visual impairment most commonly reported in the seventh decade." | 5.39 | Pregabalin in the treatment of Charles Bonnet syndrome. ( Bokdawala, RA; Sawant, NS, 2013) |
| "The purpose of this study was to investigate whether taurine ameliorate the diabetic retinopathy, and to further explore the underlying mechanisms." | 3.74 | Dietary taurine supplementation ameliorates diabetic retinopathy via anti-excitotoxicity of glutamate in streptozotocin-induced Sprague-Dawley rats. ( Chen, F; Chen, K; Mi, M; Tang, Y; Wang, J; Wei, N; Xu, H; Xu, Z; Yu, X; Zeng, K; Zhang, Q; Zhu, J, 2008) |
| "To study the levels of glutamate and gamma-aminobutyric acid (GABA) in vitreous of patients with proliferative diabetic retinopathy (PDR) and to investigate their roles in retinal ischemia." | 3.70 | Detection of glutamate and gamma-aminobutyric acid in vitreous of patients with proliferative diabetic retinopathy. ( Deng, J; Gao, R; Wu, DZ, 2000) |
| "Diabetic retinopathy is a severe retinal complication that diabetic patients are susceptible to present." | 1.46 | Retinal exposure to high glucose condition modifies the GABAergic system: Regulation by nitric oxide. ( Calaza, KC; Carpi-Santos, R; Maggesissi, RS; von Seehausen, MP, 2017) |
| "Charles Bonnet syndrome is a condition characterised by the presence of visual hallucinations in patients having visual impairment most commonly reported in the seventh decade." | 1.39 | Pregabalin in the treatment of Charles Bonnet syndrome. ( Bokdawala, RA; Sawant, NS, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (38.46) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Moore-Dotson, JM | 1 |
| Eggers, ED | 1 |
| Shivashankar, G | 1 |
| Lim, JC | 1 |
| Acosta, ML | 1 |
| Carpi-Santos, R | 1 |
| Maggesissi, RS | 1 |
| von Seehausen, MP | 1 |
| Calaza, KC | 1 |
| Sawant, NS | 1 |
| Bokdawala, RA | 1 |
| Deng, J | 1 |
| Wu, DZ | 1 |
| Gao, R | 1 |
| Yu, X | 1 |
| Xu, Z | 1 |
| Mi, M | 1 |
| Xu, H | 1 |
| Zhu, J | 1 |
| Wei, N | 1 |
| Chen, K | 1 |
| Zhang, Q | 1 |
| Zeng, K | 1 |
| Wang, J | 1 |
| Chen, F | 1 |
| Tang, Y | 1 |
| Hayreh, SS | 1 |
| Raman, R | 1 |
| Choudhari, NS | 1 |
| Kajiura, Y | 1 |
| Inoue, M | 2 |
| Yamamoto, M | 2 |
| Okada, Y | 2 |
| Ishikawa, A | 2 |
| Ishiguro, S | 2 |
| Tamai, M | 2 |
| Ambati, J | 1 |
| Chalam, KV | 1 |
| Chawla, DK | 1 |
| D'Angio, CT | 1 |
| Guillet, EG | 1 |
| Rose, SJ | 1 |
| Vanderlinde, RE | 1 |
| Ambati, BK | 1 |
| Honda, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Reducing the Intraocular Pressure by Using Alphagan Drops and Macular Edema in Patients With Diabetic Macular Edema[NCT02718547] | 25 participants (Anticipated) | Interventional | 2017-03-26 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
13 other studies available for gamma-aminobutyric acid and Diabetic Retinopathy
| Article | Year |
|---|---|
Reductions in Calcium Signaling Limit Inhibition to Diabetic Retinal Rod Bipolar Cells.
Topics: Amacrine Cells; Animals; Blood Glucose; Calcium Signaling; Diabetes Mellitus, Experimental; Diabetes | 2019 |
Proinflammatory cytokines trigger biochemical and neurochemical changes in mouse retinal explants exposed to hyperglycemic conditions.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Cytokines; Diabetic Retinopathy; Energy Metabolism | 2020 |
Retinal exposure to high glucose condition modifies the GABAergic system: Regulation by nitric oxide.
Topics: Animals; Chickens; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dose-Response Relationship | 2017 |
Pregabalin in the treatment of Charles Bonnet syndrome.
Topics: Analgesics; Diabetic Neuropathies; Diabetic Retinopathy; Female; gamma-Aminobutyric Acid; Hallucinat | 2013 |
Detection of glutamate and gamma-aminobutyric acid in vitreous of patients with proliferative diabetic retinopathy.
Topics: Diabetic Retinopathy; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Ischemia; Male; Middle | 2000 |
Dietary taurine supplementation ameliorates diabetic retinopathy via anti-excitotoxicity of glutamate in streptozotocin-induced Sprague-Dawley rats.
Topics: Amino Acid Transport System X-AG; Animals; Blood Glucose; Blotting, Western; Body Weight; Diabetes M | 2008 |
Role of retinal hypoxia in diabetic macular edema: a new concept.
Topics: Adult; Blood Pressure; Diabetic Nephropathies; Diabetic Retinopathy; Female; Fluorescein Angiography | 2008 |
Central retinal vein occlusion with non-arteritic ischemic optic neuropathy and cystoid macular edema.
Topics: Blood Pressure; Diabetic Retinopathy; Fluorescein Angiography; gamma-Aminobutyric Acid; Humans; Hypo | 2008 |
[Alteration of gamma-aminobutyric acid in streptozotocin-induced diabetic rat retina].
Topics: Action Potentials; Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Electroretinograp | 1994 |
Changes in GABA metabolism in streptozotocin-induced diabetic rat retinas.
Topics: 4-Aminobutyrate Transaminase; Amino Acids; Animals; Diabetes Mellitus, Experimental; Diabetic Retino | 1996 |
Accumulation of gamma-aminobutyric acid in diabetic rat retinal Müller cells evidenced by electron microscopic immunocytochemistry.
Topics: Animals; Antibody Specificity; Cross Reactions; Diabetes Mellitus, Experimental; Diabetic Retinopath | 1996 |
Elevated gamma-aminobutyric acid, glutamate, and vascular endothelial growth factor levels in the vitreous of patients with proliferative diabetic retinopathy.
Topics: Chromatography, High Pressure Liquid; Diabetic Retinopathy; Endothelial Growth Factors; Enzyme-Linke | 1997 |
Alteration of the GABAergic neuronal system of the retina and superior colliculus in streptozotocin-induced diabetic rat.
Topics: 4-Aminobutyrate Transaminase; Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Diseas | 1998 |