gamma-aminobutyric acid has been researched along with DiGeorge Syndrome in 7 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
DiGeorge Syndrome: Congenital syndrome characterized by a wide spectrum of characteristics including the absence of the THYMUS and PARATHYROID GLANDS resulting in T-cell immunodeficiency, HYPOCALCEMIA, defects in the outflow tract of the heart, and craniofacial anomalies.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here we discuss this disease concept in the context of our recent findings demonstrating that neural dysfunction arising from accumulation of the schizophrenia-associated metabolite l-proline is due to its structural mimicry of the neurotransmitter GABA that leads to alterations in GABA-ergic short-term synaptic plasticity." | 3.88 | Role of Endogenous Metabolite Alterations in Neuropsychiatric Disease. ( Crabtree, GW; Gogos, JA, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Larsen, KM | 1 |
| Mancini, V | 1 |
| Saleh, MG | 1 |
| Delavari, F | 1 |
| Bagautdinova, J | 1 |
| Eliez, S | 1 |
| Vingerhoets, C | 1 |
| Tse, DH | 1 |
| van Oudenaren, M | 1 |
| Hernaus, D | 1 |
| van Duin, E | 1 |
| Zinkstok, J | 1 |
| Ramaekers, JG | 1 |
| Jansen, JF | 1 |
| McAlonan, G | 1 |
| van Amelsvoort, T | 1 |
| Amin, H | 1 |
| Marinaro, F | 1 |
| De Pietri Tonelli, D | 1 |
| Berdondini, L | 1 |
| Crabtree, GW | 1 |
| Gogos, JA | 1 |
| Mori, T | 1 |
| Mori, K | 1 |
| Fujii, E | 1 |
| Toda, Y | 1 |
| Miyazaki, M | 1 |
| Harada, M | 1 |
| Kagami, S | 1 |
| Kimoto, S | 1 |
| Muraki, K | 1 |
| Toritsuka, M | 1 |
| Mugikura, S | 1 |
| Kajiwara, K | 1 |
| Kishimoto, T | 1 |
| Illingworth, E | 1 |
| Tanigaki, K | 1 |
1 trial available for gamma-aminobutyric acid and DiGeorge Syndrome
| Article | Year |
|---|---|
Glutamatergic and GABAergic reactivity and cognition in 22q11.2 deletion syndrome and healthy volunteers: A randomized double-blind 7-Tesla pharmacological MRS study.
Topics: Adult; Attention; Cognition; Corpus Striatum; Cross-Over Studies; DiGeorge Syndrome; Double-Blind Me | 2020 |
6 other studies available for gamma-aminobutyric acid and DiGeorge Syndrome
| Article | Year |
|---|---|
Auditory Steady-State Responses Probe GABA-Related Oscillatory Cortical Circuits and Their Relation to Neurodevelopmental Mental Disorders.
Topics: Adolescent; Communication; DiGeorge Syndrome; Evoked Potentials, Auditory; gamma-Aminobutyric Acid; | 2022 |
Excitatory/Inhibitory Imbalance Underlies Hippocampal Atrophy in Individuals With 22q11.2 Deletion Syndrome With Psychotic Symptoms.
Topics: Atrophy; DiGeorge Syndrome; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hippocampus; Humans; | 2023 |
Developmental excitatory-to-inhibitory GABA-polarity switch is disrupted in 22q11.2 deletion syndrome: a potential target for clinical therapeutics.
Topics: Animals; Bumetanide; DiGeorge Syndrome; Disease Models, Animal; gamma-Aminobutyric Acid; Hippocampus | 2017 |
Role of Endogenous Metabolite Alterations in Neuropsychiatric Disease.
Topics: DiGeorge Syndrome; gamma-Aminobutyric Acid; Humans; Metabolism, Inborn Errors; Metabolomics; Molecul | 2018 |
Neuroradiological and neurofunctional examinations for patients with 22q11.2 deletion.
Topics: Case-Control Studies; Child; Child, Preschool; DiGeorge Syndrome; Electroencephalography; Epilepsy; | 2011 |
Selective overexpression of Comt in prefrontal cortex rescues schizophrenia-like phenotypes in a mouse model of 22q11 deletion syndrome.
Topics: Animals; Benzodiazepinones; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; DiGe | 2012 |