gamma-aminobutyric acid has been researched along with Developmental Psychomotor Disorders in 12 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The association of macrocephaly, dystonia, and bilateral temporal arachnoid cysts, shown either by computed tomography or magnetic resonance imaging, seems to be diagnostic of glutaric aciduria type 1." | 5.29 | Macrocephaly, dystonia, and bilateral temporal arachnoid cysts: glutaric aciduria type 1. ( Casas, C; Fernández, MA; Martínez-Lage, JF; Poza, M; Puche, A; Rodriguez Costa, T, 1994) |
| "The initial diagnosis was of hydrocephalus and bilateral temporal cerebrospinal fluid collections." | 5.29 | Macrocephaly, dystonia, and bilateral temporal arachnoid cysts: glutaric aciduria type 1. ( Casas, C; Fernández, MA; Martínez-Lage, JF; Poza, M; Puche, A; Rodriguez Costa, T, 1994) |
| "To review and summarize the currently available data on the use of anticonvulsant mood stabilizers (carbamazepine, valproic acid, gabapentin, lamotrigine, topiramate) in the treatment of behavioral and psychological symptoms of dementia (BPSD); to determine whether these medications can be recommended for routine clinical use." | 4.84 | Anticonvulsants for the treatment of behavioral and psychological symptoms of dementia: a literature review. ( Konovalov, S; Muralee, S; Tampi, RR, 2008) |
| "After adolescence, recurrent affective psychoses are relatively frequent, especially in patients with uniparental disomy." | 2.43 | Prader-Willi syndrome: atypical psychoses and motor dysfunctions. ( Tuinier, S; Verhoeven, WM, 2006) |
| "A 24-year-old woman with major depressive disorder (MDD) with reduced psychomotor activity was identified with unusually high serum GAD65 and Ro52 autoantibody titers." | 1.36 | High levels of Anti-GAD65 and Anti-Ro52 autoantibodies in a patient with major depressive disorder showing psychomotor disturbance. ( Burbelo, PD; Carlson, PJ; Ching, KH; Drevets, WC; Iadarola, MJ, 2010) |
| "We have generated a FTLD-U mouse model (CaMKII-TDP-43 Tg) in which TDP-43 is transgenically overexpressed in the forebrain resulting in phenotypic characteristics mimicking those of FTLD-U." | 1.36 | Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U. ( Chien, WL; Cho, KH; Fang, YH; Fu, WM; Lin, CP; Shen, CK; Tsai, KJ; Wang, WT; Wu, TW; Yang, CH, 2010) |
| "Rett syndrome is characterized by apparently normal early development followed by regression, motor abnormalities, seizures and features of autism, especially stereotyped behaviours." | 1.36 | Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes. ( Chahrour, M; Chao, HT; Chen, H; Ekker, M; Gong, S; Heintz, N; Lu, HC; Neul, JL; Noebels, JL; Rosenmund, C; Rubenstein, JL; Samaco, RC; Xue, M; Yoo, J; Zoghbi, HY, 2010) |
| "Patients with hepatic encephalopathy show altered motor function, psychomotor slowing and hypokinesia." | 1.33 | Hypolocomotion in rats with chronic liver failure is due to increased glutamate and activation of metabotropic glutamate receptors in substantia nigra. ( Cauli, O; Erceg, S; Felipo, V; Llansola, M, 2006) |
| "Vigabatrin (VGB) was specifically synthesized to enhance inhibitory GABAergic transmission by elevating GABA levels via irreversible inhibition of GABA transaminase." | 1.30 | [Monotherapy with vigabatrin in the treatment of West's syndrome]. ( Castro, E; Ocaña, O; Rufo, M; Santiago, C, 1997) |
| "The association of macrocephaly, dystonia, and bilateral temporal arachnoid cysts, shown either by computed tomography or magnetic resonance imaging, seems to be diagnostic of glutaric aciduria type 1." | 1.29 | Macrocephaly, dystonia, and bilateral temporal arachnoid cysts: glutaric aciduria type 1. ( Casas, C; Fernández, MA; Martínez-Lage, JF; Poza, M; Puche, A; Rodriguez Costa, T, 1994) |
| "The initial diagnosis was of hydrocephalus and bilateral temporal cerebrospinal fluid collections." | 1.29 | Macrocephaly, dystonia, and bilateral temporal arachnoid cysts: glutaric aciduria type 1. ( Casas, C; Fernández, MA; Martínez-Lage, JF; Poza, M; Puche, A; Rodriguez Costa, T, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dadsetan, S | 1 |
| Balzano, T | 1 |
| Forteza, J | 1 |
| Agusti, A | 1 |
| Cabrera-Pastor, A | 1 |
| Taoro-Gonzalez, L | 1 |
| Hernandez-Rabaza, V | 1 |
| Gomez-Gimenez, B | 1 |
| ElMlili, N | 1 |
| Llansola, M | 2 |
| Felipo, V | 2 |
| Ching, KH | 1 |
| Burbelo, PD | 1 |
| Carlson, PJ | 1 |
| Drevets, WC | 1 |
| Iadarola, MJ | 1 |
| Tsai, KJ | 1 |
| Yang, CH | 1 |
| Fang, YH | 1 |
| Cho, KH | 1 |
| Chien, WL | 1 |
| Wang, WT | 1 |
| Wu, TW | 1 |
| Lin, CP | 1 |
| Fu, WM | 1 |
| Shen, CK | 1 |
| Chao, HT | 1 |
| Chen, H | 1 |
| Samaco, RC | 1 |
| Xue, M | 1 |
| Chahrour, M | 1 |
| Yoo, J | 1 |
| Neul, JL | 1 |
| Gong, S | 1 |
| Lu, HC | 1 |
| Heintz, N | 1 |
| Ekker, M | 1 |
| Rubenstein, JL | 1 |
| Noebels, JL | 1 |
| Rosenmund, C | 1 |
| Zoghbi, HY | 1 |
| Arvio, M | 1 |
| Sipilä, I | 1 |
| White, HS | 1 |
| Watson, WP | 1 |
| Hansen, SL | 1 |
| Slough, S | 1 |
| Perregaard, J | 1 |
| Sarup, A | 1 |
| Bolvig, T | 1 |
| Petersen, G | 1 |
| Larsson, OM | 1 |
| Clausen, RP | 1 |
| Frølund, B | 1 |
| Falch, E | 1 |
| Krogsgaard-Larsen, P | 1 |
| Schousboe, A | 1 |
| Verhoeven, WM | 1 |
| Tuinier, S | 1 |
| Cauli, O | 1 |
| Erceg, S | 1 |
| Konovalov, S | 1 |
| Muralee, S | 1 |
| Tampi, RR | 1 |
| Martínez-Lage, JF | 1 |
| Casas, C | 1 |
| Fernández, MA | 1 |
| Puche, A | 1 |
| Rodriguez Costa, T | 1 |
| Poza, M | 1 |
| Rufo, M | 1 |
| Santiago, C | 1 |
| Castro, E | 1 |
| Ocaña, O | 1 |
| Ishiguro, Y | 1 |
| Kajita, M | 1 |
| Aoshima, T | 1 |
| Watanabe, K | 1 |
| Kimura, M | 1 |
| Yamaguchi, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Magnetic Resonance Imaging of the Brain in Children With Autism Spectrum Disorder (ASD)[NCT05758220] | 25 participants (Anticipated) | Observational [Patient Registry] | 2023-04-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for gamma-aminobutyric acid and Developmental Psychomotor Disorders
| Article | Year |
|---|---|
Prader-Willi syndrome: atypical psychoses and motor dysfunctions.
Topics: Adolescent; Adult; Female; gamma-Aminobutyric Acid; Humans; Male; Prader-Willi Syndrome; Psychomotor | 2006 |
Anticonvulsants for the treatment of behavioral and psychological symptoms of dementia: a literature review.
Topics: Aggression; Amines; Anticonvulsants; Carbamazepine; Cognition Disorders; Cyclohexanecarboxylic Acids | 2008 |
10 other studies available for gamma-aminobutyric acid and Developmental Psychomotor Disorders
| Article | Year |
|---|---|
Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy.
Topics: Animals; Anti-Inflammatory Agents; Cerebellum; Cyclic GMP; Cytokines; Dinoprostone; Disease Models, | 2016 |
High levels of Anti-GAD65 and Anti-Ro52 autoantibodies in a patient with major depressive disorder showing psychomotor disturbance.
Topics: Adult; Autoantibodies; Autoimmunity; Biomarkers; Brain; Brain Chemistry; Depressive Disorder, Major; | 2010 |
Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U.
Topics: Animals; Apoptosis; Atrophy; Brain; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Caspase 3; C | 2010 |
Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes.
Topics: Animals; Autistic Disorder; Brain; Compulsive Behavior; Disease Models, Animal; Electroencephalograp | 2010 |
[Psychomotor slowness of a mentally retarded woman].
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Clobazam; Cyclohexan | 2001 |
First demonstration of a functional role for central nervous system betaine/{gamma}-aminobutyric acid transporter (mGAT2) based on synergistic anticonvulsant action among inhibitors of mGAT1 and mGAT2.
Topics: Acoustic Stimulation; Acyltransferases; Amygdala; Animals; Anticonvulsants; Behavior, Animal; Cells, | 2005 |
Hypolocomotion in rats with chronic liver failure is due to increased glutamate and activation of metabotropic glutamate receptors in substantia nigra.
Topics: Animals; Basal Ganglia; Chromones; Chronic Disease; GABA Antagonists; gamma-Aminobutyric Acid; Gluta | 2006 |
Macrocephaly, dystonia, and bilateral temporal arachnoid cysts: glutaric aciduria type 1.
Topics: Arachnoid Cysts; Brain; Brain Diseases; Carnitine; Dystonia; Female; gamma-Aminobutyric Acid; Glutar | 1994 |
[Monotherapy with vigabatrin in the treatment of West's syndrome].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Female; gamma-Aminobutyric Acid; Humans; Infant; Male; | 1997 |
The first case of 4-hydroxybutyric aciduria in Japan.
Topics: Aldehyde Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Brain; gamma-Aminobutyric Acid; Huma | 2001 |