gamma-aminobutyric acid has been researched along with Demyelinating Diseases in 7 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Demyelinating Diseases: Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pyridoxine-dependent seizures are a disorder of GABA metabolism probably due to a defective binding of pyridoxal phosphate coenzyme (PALP) with glutamate decarboxylase (GAD), the rate-limiting enzyme in GABA synthesis." | 7.69 | Pyridoxine-dependent seizures associated with white matter abnormalities. ( Giugliani, R; Jardim, LB; Kliemann, FA; Martins, CE; Pires, RF; Vargas, CR; Vizioli, J, 1994) |
| "Pyridoxine-dependent seizures are a disorder of GABA metabolism probably due to a defective binding of pyridoxal phosphate coenzyme (PALP) with glutamate decarboxylase (GAD), the rate-limiting enzyme in GABA synthesis." | 5.29 | Pyridoxine-dependent seizures associated with white matter abnormalities. ( Giugliani, R; Jardim, LB; Kliemann, FA; Martins, CE; Pires, RF; Vargas, CR; Vizioli, J, 1994) |
| "Pyridoxine-dependent seizures are a disorder of GABA metabolism probably due to a defective binding of pyridoxal phosphate coenzyme (PALP) with glutamate decarboxylase (GAD), the rate-limiting enzyme in GABA synthesis." | 3.69 | Pyridoxine-dependent seizures associated with white matter abnormalities. ( Giugliani, R; Jardim, LB; Kliemann, FA; Martins, CE; Pires, RF; Vargas, CR; Vizioli, J, 1994) |
| "Although mouse models of experimental autoimmune encephalomyelitis (EAE) have provided insight on the pathobiology of MS-induced neuropathic pain, concurrent severe motor impairments confound quantitative assessment of pain behaviors over the disease course." | 1.40 | Establishment and characterization of an optimized mouse model of multiple sclerosis-induced neuropathic pain using behavioral, pharmacologic, histologic and immunohistochemical methods. ( Khan, N; Smith, MT; Woodruff, TM, 2014) |
| "Mechanical allodynia was fully developed by 28-30days post-immunization (p." | 1.40 | Establishment and characterization of an optimized mouse model of multiple sclerosis-induced neuropathic pain using behavioral, pharmacologic, histologic and immunohistochemical methods. ( Khan, N; Smith, MT; Woodruff, TM, 2014) |
| "In ethidium bromide treated rats, gabapentin administered at 300 mg/kg increased cortical MDA by 66%." | 1.38 | The effect of gabapentin on oxidative stress in a model of toxic demyelination in rat brain. ( Abdel-Salam, OM; Khadrawy, YA; Mohammed, NA; Youness, ER, 2012) |
| "Pyridoxine-dependent seizures are a disorder of GABA metabolism probably due to a defective binding of pyridoxal phosphate coenzyme (PALP) with glutamate decarboxylase (GAD), the rate-limiting enzyme in GABA synthesis." | 1.29 | Pyridoxine-dependent seizures associated with white matter abnormalities. ( Giugliani, R; Jardim, LB; Kliemann, FA; Martins, CE; Pires, RF; Vargas, CR; Vizioli, J, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kiljan, S | 1 |
| Prins, M | 1 |
| Baselmans, BM | 1 |
| Bol, JGJM | 1 |
| Schenk, GJ | 1 |
| van Dam, AM | 1 |
| Khan, N | 1 |
| Woodruff, TM | 1 |
| Smith, MT | 1 |
| Zonouzi, M | 1 |
| Scafidi, J | 1 |
| Li, P | 1 |
| McEllin, B | 1 |
| Edwards, J | 1 |
| Dupree, JL | 1 |
| Harvey, L | 1 |
| Sun, D | 1 |
| Hübner, CA | 1 |
| Cull-Candy, SG | 1 |
| Farrant, M | 1 |
| Gallo, V | 1 |
| Abdel-Salam, OM | 1 |
| Khadrawy, YA | 1 |
| Mohammed, NA | 1 |
| Youness, ER | 1 |
| Baumann, N | 1 |
| Maurin, Y | 1 |
| Puech, A | 1 |
| Chauvel, P | 1 |
| Simon, P | 1 |
| Jardim, LB | 1 |
| Pires, RF | 1 |
| Martins, CE | 1 |
| Vargas, CR | 1 |
| Vizioli, J | 1 |
| Kliemann, FA | 1 |
| Giugliani, R | 1 |
| Pozdniakov, AV | 1 |
| Tiutin, LA | 1 |
| Bisaga, GN | 1 |
| Odinak, MM | 1 |
7 other studies available for gamma-aminobutyric acid and Demyelinating Diseases
| Article | Year |
|---|---|
Enhanced GABAergic Immunoreactivity in Hippocampal Neurons and Astroglia of Multiple Sclerosis Patients.
Topics: Adult; Aged; Aged, 80 and over; Astrocytes; Demyelinating Diseases; Female; gamma-Aminobutyric Acid; | 2019 |
Establishment and characterization of an optimized mouse model of multiple sclerosis-induced neuropathic pain using behavioral, pharmacologic, histologic and immunohistochemical methods.
Topics: Amines; Amitriptyline; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cyclohexanecarboxyli | 2014 |
GABAergic regulation of cerebellar NG2 cell development is altered in perinatal white matter injury.
Topics: Action Potentials; Animals; Animals, Newborn; Asphyxia Neonatorum; Carbachol; Cell Count; Cells, Cul | 2015 |
The effect of gabapentin on oxidative stress in a model of toxic demyelination in rat brain.
Topics: Amines; Animals; Antioxidants; Cerebral Cortex; Cyclohexanecarboxylic Acids; Demyelinating Diseases; | 2012 |
[Biochemical and pharmacological approach to the functional disorders observed in demyelination mutants (GABAergic and noradrenergic systems)].
Topics: Animals; Central Nervous System; Demyelinating Diseases; gamma-Aminobutyric Acid; Membrane Proteins; | 1980 |
Pyridoxine-dependent seizures associated with white matter abnormalities.
Topics: Brain; Child, Preschool; Demyelinating Diseases; gamma-Aminobutyric Acid; Humans; Male; Nerve Tissue | 1994 |
[Proton magnetic-resonance spectroscopy in remitting and secondary-progressive multiple sclerosis].
Topics: Adolescent; Adult; Aspartic Acid; Brain; Choline; Creatine; Demyelinating Diseases; Female; gamma-Am | 2001 |