Page last updated: 2024-10-16

gamma-aminobutyric acid and Delirium of Mixed Origin

gamma-aminobutyric acid has been researched along with Delirium of Mixed Origin in 23 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Research Excerpts

ExcerptRelevanceReference
"Although postoperative opioid use was reduced, perioperative administration of gabapentin did not result in a reduction of postoperative delirium or hospital length of stay."9.24Perioperative Gabapentin Does Not Reduce Postoperative Delirium in Older Surgical Patients: A Randomized Clinical Trial. ( Ames, C; Berven, S; Bozic, K; Burch, S; Chang, S; Chen, N; Chou, D; Covinsky, K; Deviren, V; Kinjo, S; Kramer, JH; Leung, JM; Meckler, G; Newman, S; Ries, M; Sands, LP; Tay, B; Tsai, T; Vail, T; Voss, V; Weinstein, P; Youngblom, E, 2017)
"In this randomized pilot clinical trial, the authors tested the hypothesis that using gabapentin as an add-on agent in the treatment of postoperative pain reduces the occurrence of postoperative delirium."9.12Pilot clinical trial of gabapentin to decrease postoperative delirium in older patients. ( Ames, C; Chou, D; Dahl, JB; Leung, JM; Petersen, KL; Rico, M; Rowbotham, MC; Sands, LP; Weinstein, P, 2006)
"Gabapentin (Neurontin) is approved by the US Food and Drug Administration for treatment of epilepsy and post-herpetic neuralgia."7.75Gabapentin-induced delirium and dependence. ( Kahn, DA; Kruszewski, SP; Paczynski, RP, 2009)
"Gabapentin was shown to be opioid sparing, with lower doses for the intervention group versus the control group."6.84Perioperative Gabapentin Does Not Reduce Postoperative Delirium in Older Surgical Patients: A Randomized Clinical Trial. ( Ames, C; Berven, S; Bozic, K; Burch, S; Chang, S; Chen, N; Chou, D; Covinsky, K; Deviren, V; Kinjo, S; Kramer, JH; Leung, JM; Meckler, G; Newman, S; Ries, M; Sands, LP; Tay, B; Tsai, T; Vail, T; Voss, V; Weinstein, P; Youngblom, E, 2017)
"Delirium is a common complication in postoperative, critically ill patients."5.40The association of plasma gamma-aminobutyric acid concentration with postoperative delirium in critically ill patients. ( Egi, M; Kanazawa, T; Morita, K; Toda, Y; Yoshitaka, S, 2014)
"Gabapentin is a central nervous system inhibitory agent with likely gamma-aminobutyric acid (GABA)-ergic and non-GABAergic mechanisms of action."5.35Gabapentin-induced delirium and dependence. ( Kahn, DA; Kruszewski, SP; Paczynski, RP, 2009)
"Although postoperative opioid use was reduced, perioperative administration of gabapentin did not result in a reduction of postoperative delirium or hospital length of stay."5.24Perioperative Gabapentin Does Not Reduce Postoperative Delirium in Older Surgical Patients: A Randomized Clinical Trial. ( Ames, C; Berven, S; Bozic, K; Burch, S; Chang, S; Chen, N; Chou, D; Covinsky, K; Deviren, V; Kinjo, S; Kramer, JH; Leung, JM; Meckler, G; Newman, S; Ries, M; Sands, LP; Tay, B; Tsai, T; Vail, T; Voss, V; Weinstein, P; Youngblom, E, 2017)
"In this randomized pilot clinical trial, the authors tested the hypothesis that using gabapentin as an add-on agent in the treatment of postoperative pain reduces the occurrence of postoperative delirium."5.12Pilot clinical trial of gabapentin to decrease postoperative delirium in older patients. ( Ames, C; Chou, D; Dahl, JB; Leung, JM; Petersen, KL; Rico, M; Rowbotham, MC; Sands, LP; Weinstein, P, 2006)
"Gabapentin (Neurontin) is approved by the US Food and Drug Administration for treatment of epilepsy and post-herpetic neuralgia."3.75Gabapentin-induced delirium and dependence. ( Kahn, DA; Kruszewski, SP; Paczynski, RP, 2009)
"Gabapentin was shown to be opioid sparing, with lower doses for the intervention group versus the control group."2.84Perioperative Gabapentin Does Not Reduce Postoperative Delirium in Older Surgical Patients: A Randomized Clinical Trial. ( Ames, C; Berven, S; Bozic, K; Burch, S; Chang, S; Chen, N; Chou, D; Covinsky, K; Deviren, V; Kinjo, S; Kramer, JH; Leung, JM; Meckler, G; Newman, S; Ries, M; Sands, LP; Tay, B; Tsai, T; Vail, T; Voss, V; Weinstein, P; Youngblom, E, 2017)
"Delirium is a very common and serious disorder with high morbidity and mortality."2.45Pharmacological treatment for the prevention of delirium: review of current evidence. ( Howard, R; Tabet, N, 2009)
"However, delirium is underrecognized and undertreated because of its heterogeneous and fluctuating presentation and due to the limitations in resources and training in contemporary clinical settings."2.44Delirium: where do we stand? ( Han, C; Marks, DM; Masand, P; Pae, CU; Patkar, AA, 2008)
"Gabapentin is a second generation anticonvulsant that is effective in the treatment of chronic neuropathic pain."2.44Gabapentin: a multimodal perioperative drug? ( Irwin, MG; Kong, VK, 2007)
"Infant delirium is an under-recognized clinical entity in neonatal intensive care, and earlier identification and treatment could minimize morbidities associated with this condition."1.46A case of infant delirium in the neonatal intensive care unit. ( Bidegain, M; Cotten, CM; Edwards, LE; Hornik, CD; Hutchison, LB; Smith, PB, 2017)
"Delirium is a common complication in postoperative, critically ill patients."1.40The association of plasma gamma-aminobutyric acid concentration with postoperative delirium in critically ill patients. ( Egi, M; Kanazawa, T; Morita, K; Toda, Y; Yoshitaka, S, 2014)
"Delirium is still one of the most common and distressing symptoms in palliative care patients."1.38Reversible delirium in an advanced cancer patient. ( Jagsch, C; Kierner, KA; Watzke, HH, 2012)
"Gabapentin is a central nervous system inhibitory agent with likely gamma-aminobutyric acid (GABA)-ergic and non-GABAergic mechanisms of action."1.35Gabapentin-induced delirium and dependence. ( Kahn, DA; Kruszewski, SP; Paczynski, RP, 2009)
"Delirium is thought to be a temporary psychiatric disorder resulting from a reduced central cholinergic transmission, combined with an increased dopaminergic transmission."1.33Psychotogenic drugs and delirium pathogenesis: the central role of the thalamus. ( Gagnon, P; Gaudreau, JD, 2005)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.70)18.7374
1990's0 (0.00)18.2507
2000's8 (34.78)29.6817
2010's12 (52.17)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Cooper, JJ1
Ross, DA1
Joshi, YB1
Friend, SF1
Jimenez, B1
Steiger, LR1
Leung, JM2
Sands, LP2
Chen, N1
Ames, C2
Berven, S1
Bozic, K1
Burch, S1
Chou, D2
Covinsky, K1
Deviren, V1
Kinjo, S1
Kramer, JH1
Ries, M1
Tay, B1
Vail, T1
Weinstein, P2
Chang, S1
Meckler, G1
Newman, S1
Tsai, T1
Voss, V1
Youngblom, E1
Regan, DW1
Kashiwagi, D1
Dougan, B1
Sundsted, K1
Mauck, K1
Di Fabio, R1
D'Agostino, C1
Baldi, G1
Pierelli, F1
Salman, AE1
Camkıran, A1
Oğuz, S1
Dönmez, A1
Dighe, K1
Clarke, H1
McCartney, CJ1
Wong, CL1
Yoshitaka, S1
Egi, M1
Kanazawa, T1
Toda, Y1
Morita, K1
Downes, MA1
Berling, IL1
Mostafa, A1
Grice, J1
Roberts, MS1
Isbister, GK1
Lee, YI1
Chen, L1
Smith, RL1
Edwards, LE1
Hutchison, LB1
Hornik, CD1
Smith, PB1
Cotten, CM1
Bidegain, M1
Pae, CU1
Marks, DM1
Han, C1
Patkar, AA1
Masand, P1
Tabet, N1
Howard, R1
Kruszewski, SP1
Paczynski, RP1
Kahn, DA1
Kierner, KA1
Jagsch, C1
Watzke, HH1
Pedroso, JL1
Nakama, GY1
Carneiro Filho, M1
Barsottini, OG1
MORRONI, OB1
Kaneko, Y1
Yanagihara, K1
Kohno, S1
Gaudreau, JD1
Gagnon, P1
Rico, M1
Petersen, KL1
Rowbotham, MC1
Dahl, JB1
Bhat, R1
Rockwood, K1
Kong, VK1
Irwin, MG1
Cowen, PJ1
Nutt, DJ1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clinical Trial of Gabapentin to Decrease Postoperative Delirium and Pain in Surgical Patients[NCT00221338]Phase 3750 participants (Actual)Interventional2006-01-31Completed
The Preventative Role of Exogenous Melatonin Administration in Patients With Advanced Cancer Who Are at Risk of Delirium: a Feasibility Study Prior to a Larger Randomized Controlled Trial[NCT02200172]Phase 260 participants (Actual)Interventional2014-12-31Completed
A Randomized, Double-blind, Placebo-controlled Trial to Assess the Safety and Efficacy of the Perioperative Administration of Pregabalin in Reducing the Incidence of Postoperative Delirium and Improving Acute Postoperative Pain Management[NCT00819988]Phase 3240 participants (Actual)Interventional2009-05-31Completed
Usefulness of Bright Light Therapy in the Prevention of Delirium in Patients Undergoing Hematopoietic Stem Cell Transplant (HSCT)[NCT01700816]40 participants (Actual)Interventional2012-10-31Terminated (stopped due to Low incidence of delirium.)
The Impact of Perioperative Gabapentin on Chronic Groin Pain After Inguinal Hernia Repair[NCT02419443]Phase 4100 participants (Anticipated)Interventional2011-08-31Active, not recruiting
Effect of Preoperative Pregabalin on Propofol Induction Dose[NCT01158859]Phase 450 participants (Anticipated)Interventional2010-04-30Completed
The Effect of Gabapentin on Acute Pain and PONV in Bariatric Surgical Patients[NCT00886236]62 participants (Actual)Interventional2008-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Hospital Length of Stay

(NCT00221338)
Timeframe: Typically within the first week after surgery

Interventiondays (Mean)
Gabapentin4.4
Placebo4.1

Incidence of Postoperative Delirium by Study Group

Number of subjects who developed postoperative delirium, as measured by the Confusion Assessment Method, a validated tool for assessing delirium based on DSM-III-R, on any of the first three postoperative days. (NCT00221338)
Timeframe: postoperative days 1, 2 and 3

InterventionParticipants (Count of Participants)
Gabapentin84
Placebo72

Median Postoperative Opioid Doses Across Study Follow up Period

Postoperative intravenous opioid doses converted to morphine equivalents. Median derived from total opioid doses on first, second and third postoperative days. (NCT00221338)
Timeframe: Study follow up period: postoperative days 1, 2 and 3

Interventionmorphine equivalents, mg (Median)
Gabapentin6.7
Placebo6.7

Postoperative Pain Score - Postoperative Day 1

Postoperative pain as measured by Visual Analog Pain scale (0=no pain, 10=worst pain imaginable). (NCT00221338)
Timeframe: Postoperative day 1

Interventionscore on a scale (Mean)
Gabapentin4
Placebo4

Postoperative Pain Score - Postoperative Day 2

Postoperative pain as measured by Visual Analog Pain scale (0=no pain, 10=worst pain imaginable). (NCT00221338)
Timeframe: Postoperative day 2

Interventionscore on a scale (Mean)
Gabapentin3
Placebo4

Postoperative Pain Score - Postoperative Day 3

Postoperative pain as measured by Visual Analog Pain scale (0=no pain, 10=worst pain imaginable). (NCT00221338)
Timeframe: Postoperative day 3

Interventionscore on a scale (Mean)
Gabapentin3
Placebo3

Hematocrit (HCT)

Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant

Interventionvolume percentage (vol%) of red blood ce (Median)
Bright Light Therapy28.20
Sham Light26.70

Hemoglobin (HGB)

Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant

Interventiong/dl (Median)
Bright Light Therapy9.70
Sham Light9.55

Hospital Length of Stay

(NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant

Interventiondays (Median)
Bright Light Therapy18
Sham Light18.5

Number of Participants Who Developed Delirium Based on Meeting Criteria on the Delirium Rating Scale and/or Memorial Delirium Assessment Scale

Monday, Wednesday, and Friday assessments will begin after beginning light therapy and include the Delirium Rating Scale-Revised-98 (DRS-98)and Memorial Delirium Assessment Scale (MDAS) (NCT01700816)
Timeframe: From hospital admission until the date of first documented delirium, assessed up to 28 days post-transplant

InterventionParticipants (Count of Participants)
Bright Light Therapy1
Sham Light0

Platelet Count

Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant

Interventionthousand cells/uL (Median)
Bright Light Therapy39
Sham Light33.5

Red Blood Cells (RBC)

Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant

InterventionM/uL (Median)
Bright Light Therapy3.21
Sham Light2.93

Severity of Delirium Episodes: Memorial Delirium Assessment Scale (MDAS)

"Monday, Wednesday, and Friday assessments of the Memorial Delirium Assessment Scale (MDAS); Patients will receive assessments after beginning light therapy until day 28 post-transplant or discharge, whichever comes first.~10 item scale Items are rated on a four-point scale from 0 (none) to 3 (severe) depending on the level of impairment, rendering a maximum possible score of 30.~A score of 13 has been recommended as a cut-off for establishing the diagnosis of delirium" (NCT01700816)
Timeframe: From first documented episode of delirium until discharge from the hospital, assessed up to 28 days post-transplant

Interventionunits on a scale (Number)
Bright Light Therapy18

White Blood Cells (WBC)

Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant

InterventionK/uL (Median)
Bright Light Therapy2.30
Sham Light4.75

Serum Creatinine and Blood Urea Nitrogen (BUN)

Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant

,
Interventionmg/dl (Median)
Serum CreatinineBlood Urea Nitrogen (BUN)
Bright Light Therapy0.669
Sham Light0.758.5

Sodium (Na), Potassium (K), Chloride (Cl), and Carbon Dioxide (CO2)

Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT (Hematopoietic Stem Cell Transplantation). (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant

,
Interventionmmol/L (Median)
Sodium (Na)Potassium (K)Chloride (Cl)Carbon Dioxide (CO2)
Bright Light Therapy1393.610524.9
Sham Light138.03.80103.025.10

Evaluate Incidence of Respiratory Depression as Evidenced by Pulse Oximetry Data

(NCT00886236)
Timeframe: 48 hours

Intervention% oxygen saturation (Mean)
1 Preoperative Gabapentin Liquid93
2 Preoperative and Postoperative Gabapentin Liquid94
3 Preoperative and Postoperative Placebo Liquid95

Evaluate the Amount of Diluadid Given Postoperatively

The amount of intraoperative and postoperative opioids used will be collected and analyzed for the three different arms. (NCT00886236)
Timeframe: 120 hours

Interventionml (Mean)
1 Preoperative Gabapentin Liquid11.035
2 Preoperative and Postoperative Gabapentin Liquid8.7
3 Preoperative and Postoperative Placebo Liquid12.4

Number of Participants Who Experience Incidence of Postoperative Nausea.

(NCT00886236)
Timeframe: 120 hours

InterventionParticipants (Count of Participants)
1 Preoperative Gabapentin Liquid12
2 Preoperative and Postoperative Gabapentin Liquid11
3 Preoperative and Postoperative Placebo Liquid12

Reviews

5 reviews available for gamma-aminobutyric acid and Delirium of Mixed Origin

ArticleYear
Update in perioperative medicine: practice changing evidence published in 2016.
    Hospital practice (1995), 2017, Volume: 45, Issue:4

    Topics: Amines; Analgesics; Anticoagulants; Antipsychotic Agents; Arthritis, Rheumatoid; Blood Transfusion;

2017
Delirium: where do we stand?
    Current psychiatry reports, 2008, Volume: 10, Issue:3

    Topics: Delirium; Diagnostic and Statistical Manual of Mental Disorders; gamma-Aminobutyric Acid; Humans; Ri

2008
Pharmacological treatment for the prevention of delirium: review of current evidence.
    International journal of geriatric psychiatry, 2009, Volume: 24, Issue:10

    Topics: Amines; Anti-Inflammatory Agents; Anticonvulsants; Antipsychotic Agents; Central Nervous System Depr

2009
[Delirium induced by antimicrobial agents].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl

    Topics: Animals; Anti-Infective Agents; Binding, Competitive; Delirium; Diagnosis, Differential; Dose-Respon

2004
Gabapentin: a multimodal perioperative drug?
    British journal of anaesthesia, 2007, Volume: 99, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Blood Pressure; Chronic Disease; Cyclohexanec

2007
Gabapentin: a multimodal perioperative drug?
    British journal of anaesthesia, 2007, Volume: 99, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Blood Pressure; Chronic Disease; Cyclohexanec

2007
Gabapentin: a multimodal perioperative drug?
    British journal of anaesthesia, 2007, Volume: 99, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Blood Pressure; Chronic Disease; Cyclohexanec

2007
Gabapentin: a multimodal perioperative drug?
    British journal of anaesthesia, 2007, Volume: 99, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Blood Pressure; Chronic Disease; Cyclohexanec

2007
Gabapentin: a multimodal perioperative drug?
    British journal of anaesthesia, 2007, Volume: 99, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Blood Pressure; Chronic Disease; Cyclohexanec

2007
Gabapentin: a multimodal perioperative drug?
    British journal of anaesthesia, 2007, Volume: 99, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Blood Pressure; Chronic Disease; Cyclohexanec

2007
Gabapentin: a multimodal perioperative drug?
    British journal of anaesthesia, 2007, Volume: 99, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Blood Pressure; Chronic Disease; Cyclohexanec

2007
Gabapentin: a multimodal perioperative drug?
    British journal of anaesthesia, 2007, Volume: 99, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Blood Pressure; Chronic Disease; Cyclohexanec

2007
Gabapentin: a multimodal perioperative drug?
    British journal of anaesthesia, 2007, Volume: 99, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Blood Pressure; Chronic Disease; Cyclohexanec

2007

Trials

4 trials available for gamma-aminobutyric acid and Delirium of Mixed Origin

ArticleYear
Perioperative Gabapentin Does Not Reduce Postoperative Delirium in Older Surgical Patients: A Randomized Clinical Trial.
    Anesthesiology, 2017, Volume: 127, Issue:4

    Topics: Aged; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Delirium; Double-Blind Me

2017
Gabapentin premedication for postoperative analgesia and emergence agitation after sevoflurane anesthesia in pediatric patients.
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2013, Volume: 25, Issue:4

    Topics: Amines; Anesthesia, General; Anesthetics, Inhalation; Anti-Anxiety Agents; Child; Child, Preschool;

2013
Perioperative gabapentin and delirium following total knee arthroplasty: a post-hoc analysis of a double-blind randomized placebo-controlled trial.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2014, Volume: 61, Issue:12

    Topics: Aged; Amines; Analgesics; Arthroplasty, Replacement, Knee; Cyclohexanecarboxylic Acids; Delirium; Do

2014
Pilot clinical trial of gabapentin to decrease postoperative delirium in older patients.
    Neurology, 2006, Oct-10, Volume: 67, Issue:7

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Delirium; Feasibility Studies; Female; Gabapentin;

2006
Pilot clinical trial of gabapentin to decrease postoperative delirium in older patients.
    Neurology, 2006, Oct-10, Volume: 67, Issue:7

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Delirium; Feasibility Studies; Female; Gabapentin;

2006
Pilot clinical trial of gabapentin to decrease postoperative delirium in older patients.
    Neurology, 2006, Oct-10, Volume: 67, Issue:7

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Delirium; Feasibility Studies; Female; Gabapentin;

2006
Pilot clinical trial of gabapentin to decrease postoperative delirium in older patients.
    Neurology, 2006, Oct-10, Volume: 67, Issue:7

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Delirium; Feasibility Studies; Female; Gabapentin;

2006
Pilot clinical trial of gabapentin to decrease postoperative delirium in older patients.
    Neurology, 2006, Oct-10, Volume: 67, Issue:7

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Delirium; Feasibility Studies; Female; Gabapentin;

2006
Pilot clinical trial of gabapentin to decrease postoperative delirium in older patients.
    Neurology, 2006, Oct-10, Volume: 67, Issue:7

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Delirium; Feasibility Studies; Female; Gabapentin;

2006
Pilot clinical trial of gabapentin to decrease postoperative delirium in older patients.
    Neurology, 2006, Oct-10, Volume: 67, Issue:7

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Delirium; Feasibility Studies; Female; Gabapentin;

2006
Pilot clinical trial of gabapentin to decrease postoperative delirium in older patients.
    Neurology, 2006, Oct-10, Volume: 67, Issue:7

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Delirium; Feasibility Studies; Female; Gabapentin;

2006
Pilot clinical trial of gabapentin to decrease postoperative delirium in older patients.
    Neurology, 2006, Oct-10, Volume: 67, Issue:7

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Delirium; Feasibility Studies; Female; Gabapentin;

2006

Other Studies

14 other studies available for gamma-aminobutyric acid and Delirium of Mixed Origin

ArticleYear
COVID-19 Catatonia-Would We Even Know?
    Biological psychiatry, 2020, 09-01, Volume: 88, Issue:5

    Topics: Akinetic Mutism; Basal Ganglia; Benzodiazepines; Betacoronavirus; Catatonia; Coronavirus Infections;

2020
Dissociative Intoxication and Prolonged Withdrawal Associated With Phenibut: A Case Report.
    Journal of clinical psychopharmacology, 2017, Volume: 37, Issue:4

    Topics: Adult; Baclofen; Delirium; GABA Agonists; gamma-Aminobutyric Acid; Humans; Male; Substance Withdrawa

2017
Delirium after gabapentin withdrawal. Case report.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2013, Volume: 40, Issue:1

    Topics: Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Delirium; Electroencephalography; Epilep

2013
The association of plasma gamma-aminobutyric acid concentration with postoperative delirium in critically ill patients.
    Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 2014, Volume: 16, Issue:4

    Topics: Critical Illness; Delirium; gamma-Aminobutyric Acid; Humans; Multivariate Analysis; Postoperative Co

2014
Acute behavioural disturbance associated with phenibut purchased via an internet supplier.
    Clinical toxicology (Philadelphia, Pa.), 2015, Volume: 53, Issue:7

    Topics: Adult; Alcohol Drinking; Delirium; Dronabinol; Emergency Service, Hospital; Female; gamma-Aminobutyr

2015
Enigmatic Fever and Delirium in a Critically Ill Patient.
    Annals of the American Thoracic Society, 2015, Volume: 12, Issue:9

    Topics: Adult; Amines; Critical Illness; Cyclohexanecarboxylic Acids; Delirium; Fever; Gabapentin; gamma-Ami

2015
A case of infant delirium in the neonatal intensive care unit.
    Journal of neonatal-perinatal medicine, 2017, Volume: 10, Issue:1

    Topics: Amines; Analgesics, Opioid; Anti-Anxiety Agents; Cardiac Catheterization; Cyclohexanecarboxylic Acid

2017
Gabapentin-induced delirium and dependence.
    Journal of psychiatric practice, 2009, Volume: 15, Issue:4

    Topics: Adult; Amines; Analgesics, Non-Narcotic; Cyclohexanecarboxylic Acids; Delirium; Gabapentin; gamma-Am

2009
Reversible delirium in an advanced cancer patient.
    Wiener medizinische Wochenschrift (1946), 2012, Volume: 162, Issue:1-2

    Topics: Amines; Analgesics; Analgesics, Opioid; Bone Neoplasms; Breast Neoplasms; Carcinoma, Intraductal, No

2012
Delirium, psychosis, and visual hallucinations induced by pregabalin.
    Arquivos de neuro-psiquiatria, 2012, Volume: 70, Issue:12

    Topics: Adult; Analgesics; Delirium; Female; gamma-Aminobutyric Acid; Hallucinations; Humans; Low Back Pain;

2012
[IMMEDIATE CLINICAL RESULTS WITH GAMMA AMINOBUTYRIC ACID B6 IN SCHIZOPHRENIAS AND DELIRIUMS].
    La Semana medica, 1963, Sep-16, Volume: 123

    Topics: Aminobutyrates; Biochemical Phenomena; Biochemistry; Delirium; gamma-Aminobutyric Acid; Mental Disor

1963
Psychotogenic drugs and delirium pathogenesis: the central role of the thalamus.
    Medical hypotheses, 2005, Volume: 64, Issue:3

    Topics: Cerebral Cortex; Corpus Striatum; Delirium; Dopamine; gamma-Aminobutyric Acid; Humans; Models, Neuro

2005
Delirium as a disorder of consciousness.
    Journal of neurology, neurosurgery, and psychiatry, 2007, Volume: 78, Issue:11

    Topics: Acetylcholine; Aged; Arousal; Attention; Awareness; Brain Stem; Cerebral Cortex; Child; Consciousnes

2007
Abstinence symptoms after withdrawal of tranquillising drugs: is there a common neurochemical mechanism?
    Lancet (London, England), 1982, Aug-14, Volume: 2, Issue:8294

    Topics: Anti-Anxiety Agents; Delirium; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Models, Biological

1982