gamma-aminobutyric acid has been researched along with Delayed Effects, Prenatal Exposure in 141 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, based on the excitatory/inhibitory imbalance theory of autism, the time window of GABA switch, the role of K-Cl co-transporter 2 (KCC2) in adjustment GABA switch, and brain permeability to erythropoietin (EPO), the effects of postnatal -EPO and- nano- erythropoietin (NEPO) have been evaluated in the valproic acid (VPA) rat model of autism." | 8.31 | The effects of postnatal erythropoietin and nano-erythropoietin on behavioral alterations by mediating K-Cl co-transporter 2 in the valproic acid-induced rat model of autism. ( Basiri, M; Darvishzadeh-Mahani, F; Haratizadeh, S; Nozari, M; Ranjbar, M, 2023) |
| "The role of gamma-aminobutyric acid (GABA) in attenuates insulin resistance (IR) in type 2 diabetic (T2D) patients and the reduction of the risk of IR in their offspring, and the function of GLUT4, IRS1 and Akt2 genes expression were investigated." | 8.02 | Gamma-aminobutyric acid attenuates insulin resistance in type 2 diabetic patients and reduces the risk of insulin resistance in their offspring. ( Rezazadeh, H; Sharifi, M; Sharifi, MR; Soltani, N, 2021) |
| "Environmental factors have been associated with psychiatric disorders and recent epidemiological studies suggest an association between prenatal lead (Pb(2+)) exposure and schizophrenia (SZ)." | 7.81 | Early-life lead exposure recapitulates the selective loss of parvalbumin-positive GABAergic interneurons and subcortical dopamine system hyperactivity present in schizophrenia. ( Guilarte, TR; Liu, X; McGlothan, JL; Ruby, KN; Soares, BD; Stansfield, KH, 2015) |
| " We have shown that perinatal exposure to bisphenol A (BPA) at environmental dose level causes long-term anxiety-like behaviors in rats." | 7.79 | Persistent overexpression of DNA methyltransferase 1 attenuating GABAergic inhibition in basolateral amygdala accounts for anxiety in rat offspring exposed perinatally to low-dose bisphenol A. ( Bai, Y; Chang, F; Chen, F; Chen, L; Zhou, R, 2013) |
| " Inhibitory gamma-aminobutyric acid (GABA) and excitatory N-methyl-D-aspartate (NMDA) systems play a role in the effect of stimulants in the genesis of epileptic seizures." | 7.76 | Effect of cross-fostering on seizures in adult male offspring of methamphetamine-treated rat mothers. ( Bernásková, K; Hrubá, L; Matejovská, I; Rokyta, R; Slamberová, R, 2010) |
| " Male offsprings were injected with EPO and NEPO in a clinically proper postnatal dosing regimen on postnatal days (PND) 1-5, and autistic-like behaviors were tested at the end of the first month." | 5.91 | The effects of postnatal erythropoietin and nano-erythropoietin on behavioral alterations by mediating K-Cl co-transporter 2 in the valproic acid-induced rat model of autism. ( Basiri, M; Darvishzadeh-Mahani, F; Haratizadeh, S; Nozari, M; Ranjbar, M, 2023) |
| " Pregnant C57BL/6 J mice were intraperitoneally injected with a dosage of 500 mg/kg valproic acid (VPA) on embryonic day 10." | 5.72 | Size anomaly and alteration of GABAergic enzymes expressions in cerebellum of a valproic acid mouse model of autism. ( Kwan, KM; Ma, SY, 2022) |
| "Bicuculline was used to investigate seizure susceptibility in pre- and peripubertal male and female rats exposed prenatally to morphine." | 5.31 | Prenatal morphine exposure alters susceptibility to bicuculline seizures in a sex- and age-specific manner. ( Schindler, CJ; Slamberová, R; Vathy, I; Velísková, J, 2000) |
| "In this study, based on the excitatory/inhibitory imbalance theory of autism, the time window of GABA switch, the role of K-Cl co-transporter 2 (KCC2) in adjustment GABA switch, and brain permeability to erythropoietin (EPO), the effects of postnatal -EPO and- nano- erythropoietin (NEPO) have been evaluated in the valproic acid (VPA) rat model of autism." | 4.31 | The effects of postnatal erythropoietin and nano-erythropoietin on behavioral alterations by mediating K-Cl co-transporter 2 in the valproic acid-induced rat model of autism. ( Basiri, M; Darvishzadeh-Mahani, F; Haratizadeh, S; Nozari, M; Ranjbar, M, 2023) |
| "The role of gamma-aminobutyric acid (GABA) in attenuates insulin resistance (IR) in type 2 diabetic (T2D) patients and the reduction of the risk of IR in their offspring, and the function of GLUT4, IRS1 and Akt2 genes expression were investigated." | 4.02 | Gamma-aminobutyric acid attenuates insulin resistance in type 2 diabetic patients and reduces the risk of insulin resistance in their offspring. ( Rezazadeh, H; Sharifi, M; Sharifi, MR; Soltani, N, 2021) |
| "Environmental factors have been associated with psychiatric disorders and recent epidemiological studies suggest an association between prenatal lead (Pb(2+)) exposure and schizophrenia (SZ)." | 3.81 | Early-life lead exposure recapitulates the selective loss of parvalbumin-positive GABAergic interneurons and subcortical dopamine system hyperactivity present in schizophrenia. ( Guilarte, TR; Liu, X; McGlothan, JL; Ruby, KN; Soares, BD; Stansfield, KH, 2015) |
| "Sulfur dioxide (SO₂) is an air pollutant that impedes neonatal development and induces adverse cardiorespiratory health effects, including tachycardia." | 3.79 | Perinatal sulfur dioxide exposure alters brainstem parasympathetic control of heart rate. ( Mendelowitz, D; Woerman, AL, 2013) |
| " We have shown that perinatal exposure to bisphenol A (BPA) at environmental dose level causes long-term anxiety-like behaviors in rats." | 3.79 | Persistent overexpression of DNA methyltransferase 1 attenuating GABAergic inhibition in basolateral amygdala accounts for anxiety in rat offspring exposed perinatally to low-dose bisphenol A. ( Bai, Y; Chang, F; Chen, F; Chen, L; Zhou, R, 2013) |
| "Cocaine abuse during pregnancy produces harmful effects not only on the mother but also on the unborn child." | 3.78 | Prenatal cocaine exposure decreases parvalbumin-immunoreactive neurons and GABA-to-projection neuron ratio in the medial prefrontal cortex. ( Bhide, PG; McCarthy, DM, 2012) |
| "Rats exposed to isoflurane in utero at a time that corresponds to the second trimester in humans have impaired spatial memory acquisition and reduced anxiety, compared with controls." | 3.77 | Rats exposed to isoflurane in utero during early gestation are behaviorally abnormal as adults. ( Baxter, MG; Crosby, G; Culley, DJ; Keel, PK; Palanisamy, A; Xie, Z, 2011) |
| "Isoflurane anesthesia was physiologically well tolerated by the dams." | 3.77 | Rats exposed to isoflurane in utero during early gestation are behaviorally abnormal as adults. ( Baxter, MG; Crosby, G; Culley, DJ; Keel, PK; Palanisamy, A; Xie, Z, 2011) |
| " Inhibitory gamma-aminobutyric acid (GABA) and excitatory N-methyl-D-aspartate (NMDA) systems play a role in the effect of stimulants in the genesis of epileptic seizures." | 3.76 | Effect of cross-fostering on seizures in adult male offspring of methamphetamine-treated rat mothers. ( Bernásková, K; Hrubá, L; Matejovská, I; Rokyta, R; Slamberová, R, 2010) |
| "Neurodevelopmental deficits of parvalbumin-immunoreactive gamma-aminobutyric acid (GABA)ergic interneurons in prefrontal cortex have been reported in schizophrenia." | 3.74 | Prenatal exposure to an NMDA receptor antagonist, MK-801 reduces density of parvalbumin-immunoreactive GABAergic neurons in the medial prefrontal cortex and enhances phencyclidine-induced hyperlocomotion but not behavioral sensitization to methamphetamine ( Abekawa, T; Ito, K; Koyama, T; Nakagawa, S, 2007) |
| "The aim of this study was to assess the effects of prenatal exposures to cannabinoids or carbon monoxide (CO) in an animal experimental model reproducing the environmental conditions in which a fetus develops whose mother, during pregnancy, ingests by smoking low doses of cannabinoids or CO." | 3.74 | Effects of prenatal exposure to the CB-1 receptor agonist WIN 55212-2 or CO on the GABAergic neuronal systems of rat cerebellar cortex. ( Ambrosi, G; Auteri, P; Benagiano, V; Bosco, L; Cagiano, R; Flace, P; Girolamo, F; Lorusso, L; Rizzi, A; Sabatini, R, 2007) |
| "Wistar rat pups were administered either a high dose of lead acetate (400 micrograms lead/g body weight/day) or a low dose (100 micrograms lead/g body weight/day) by gastric intubation, from 2 days through 60 days of age." | 3.68 | Regional alterations of brain biogenic amines and GABA/glutamate levels in rats following chronic lead exposure during neonatal development. ( Desiraju, T; Shailesh Kumar, MV, 1990) |
| "The effect of maternal alcohol consumption during pregnancy and lactation on gamma-aminobutyric acid (GABA) levels in different rat brain regions of 3-week-old pups was investigated." | 3.67 | Effect of pre- and postnatal alcohol consumption on GABA levels of various brain regions in the rat offspring. ( Ciesielski, L; Ledig, M; Lorentz, JG; Mandel, P; Simler, S, 1988) |
| " Male offsprings were injected with EPO and NEPO in a clinically proper postnatal dosing regimen on postnatal days (PND) 1-5, and autistic-like behaviors were tested at the end of the first month." | 1.91 | The effects of postnatal erythropoietin and nano-erythropoietin on behavioral alterations by mediating K-Cl co-transporter 2 in the valproic acid-induced rat model of autism. ( Basiri, M; Darvishzadeh-Mahani, F; Haratizadeh, S; Nozari, M; Ranjbar, M, 2023) |
| " Pregnant C57BL/6 J mice were intraperitoneally injected with a dosage of 500 mg/kg valproic acid (VPA) on embryonic day 10." | 1.72 | Size anomaly and alteration of GABAergic enzymes expressions in cerebellum of a valproic acid mouse model of autism. ( Kwan, KM; Ma, SY, 2022) |
| "Bisphenol A (BPA) is a well-recognized endocrine disruptor and is globally used in the manufacture of many plastic items." | 1.62 | Gamma aminobutyric acid signaling disturbances and altered astrocytic morphology associated with Bisphenol A induced cognitive impairments in rat offspring. ( Kazi, SAF; Memon, S; Nizamani, GS; Singha, SP, 2021) |
| "Depression during pregnancy has been linked to in utero stress and is associated with long-lasting symptoms in offspring, including anxiety, helplessness, attentional deficits, and social withdrawal." | 1.42 | Prenatal stress, regardless of concurrent escitalopram treatment, alters behavior and amygdala gene expression of adolescent female rats. ( Bourke, CH; Ehrlich, DE; Hazra, R; Jairam, N; Neigh, GN; Nemeth, CL; Owens, MJ; Rainnie, DG; Rowson, S; Ryan, SJ; Sholar, CA; Stowe, ZN, 2015) |
| "It was found that the experimental preeclampsia causes a delay in physical development and maturation of sensory-motor reflexes in the offspring, as indicated by the later periods of eruption of the incisors and eye opening, response to the emergence of audio and olfactory stimuli, forming vestibular stability and coordination of movements compared to pups from females with physiological pregnancy." | 1.40 | [Comparative study of the effects of new neuroactive amino acid derivatives on the postnatal development of the rat's offspring with experimental preeclampsia]. ( Lebedeva, SA; Mikhailova, LI; Perfilova, VN; Tyurenkov, IN; Zhakupova, GA, 2014) |
| "Experimental preeclampsia was modeled by replacing the drinking water by 1." | 1.40 | [Comparative study of the effects of new neuroactive amino acid derivatives on the postnatal development of the rat's offspring with experimental preeclampsia]. ( Lebedeva, SA; Mikhailova, LI; Perfilova, VN; Tyurenkov, IN; Zhakupova, GA, 2014) |
| "Sulfur dioxide (SO₂) is an air pollutant that impedes neonatal development and induces adverse cardiorespiratory health effects, including tachycardia." | 1.39 | Perinatal sulfur dioxide exposure alters brainstem parasympathetic control of heart rate. ( Mendelowitz, D; Woerman, AL, 2013) |
| "Hypothyroidism affects neurogenesis." | 1.38 | Similar distribution changes of GABAergic interneuron subpopulations in contrast to the different impact on neurogenesis between developmental and adult-stage hypothyroidism in the hippocampal dentate gyrus in rats. ( Akane, H; Mitsumori, K; Morita, R; Ohishi, T; Shibutani, M; Shiraki, A; Suzuki, K; Wang, L, 2012) |
| "Isoflurane anesthesia was physiologically well tolerated by the dams." | 1.37 | Rats exposed to isoflurane in utero during early gestation are behaviorally abnormal as adults. ( Baxter, MG; Crosby, G; Culley, DJ; Keel, PK; Palanisamy, A; Xie, Z, 2011) |
| "The nicotine-induced increase in glutamatic acid decarboxylase (GAD) and GABA(A) receptor mRNA resulted in increased GABA-induced currents and increased expression of mucin." | 1.37 | Prenatal nicotine exposure increases GABA signaling and mucin expression in airway epithelium. ( Fu, XW; Spindel, ER; Wood, K, 2011) |
| "Bicuculline was used to investigate seizure susceptibility in pre- and peripubertal male and female rats exposed prenatally to morphine." | 1.31 | Prenatal morphine exposure alters susceptibility to bicuculline seizures in a sex- and age-specific manner. ( Schindler, CJ; Slamberová, R; Vathy, I; Velísková, J, 2000) |
| "Heptachlor is a cyclodiene pesticide that was widely used for many years, and for which inadvertent exposure to children and fetuses took place in the early 1980s; yet little is known regarding the developmental neurotoxicity of it and other cyclodienes." | 1.31 | Neurotoxicological outcomes of perinatal heptachlor exposure in the rat. ( Chapin, RE; Harris, MW; Meacham, CA; Moser, VC; Shafer, TJ; Ward, TR, 2001) |
| " Pregnant Sprague-Dawley dams were dosed from gestational day (GD) 12 to postnatal day (PND) 7, whereupon the rat pups were dosed directly until PND 21 (group A) or PND 42 (group B)." | 1.31 | Neurotoxicological outcomes of perinatal heptachlor exposure in the rat. ( Chapin, RE; Harris, MW; Meacham, CA; Moser, VC; Shafer, TJ; Ward, TR, 2001) |
| "0 mg/kg dosage of 3 alpha,5 alpha-THP." | 1.30 | Prenatal stress reduces the effectiveness of the neurosteroid 3 alpha,5 alpha-THP to block kainic-acid-induced seizures. ( Bayon, LE; Frye, CA, 1999) |
| "One week after seizures, there were no differences in the water maze performance of the remaining animals." | 1.30 | Prenatal stress reduces the effectiveness of the neurosteroid 3 alpha,5 alpha-THP to block kainic-acid-induced seizures. ( Bayon, LE; Frye, CA, 1999) |
| "Phenobarbital (PB) was administered to pregnant mice during days 9-21 of gestation." | 1.27 | Effects of prenatal phenobarbital on benzodiazepine receptor development. ( Garrett, KM; Tabakoff, B, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (4.26) | 18.7374 |
| 1990's | 11 (7.80) | 18.2507 |
| 2000's | 51 (36.17) | 29.6817 |
| 2010's | 52 (36.88) | 24.3611 |
| 2020's | 21 (14.89) | 2.80 |
| Authors | Studies |
|---|---|
| Santrač, A | 1 |
| Bijelić, D | 1 |
| Stevanović, V | 1 |
| Banićević, M | 1 |
| Aranđelović, J | 1 |
| Batinić, B | 1 |
| Sharmin, D | 1 |
| Cook, JM | 1 |
| Savić, MM | 1 |
| Ma, SY | 1 |
| Kwan, KM | 1 |
| Lu, M | 1 |
| He, X | 4 |
| Jiao, Z | 3 |
| Hu, Z | 1 |
| Guo, Z | 2 |
| Dai, S | 1 |
| Wang, H | 8 |
| Xu, D | 5 |
| Singla, R | 2 |
| Mishra, A | 2 |
| Joshi, R | 1 |
| Sarma, P | 1 |
| Kumar, R | 1 |
| Kaur, G | 1 |
| Sharma, AR | 2 |
| Jain, A | 2 |
| Prakash, A | 1 |
| Bhatia, A | 1 |
| Medhi, B | 2 |
| Biosca-Brull, J | 1 |
| Guardia-Escote, L | 1 |
| Blanco, J | 1 |
| Basaure, P | 1 |
| Cabré, M | 1 |
| Sánchez-Santed, F | 1 |
| Domingo, JL | 1 |
| Colomina, MT | 1 |
| Haratizadeh, S | 1 |
| Ranjbar, M | 1 |
| Darvishzadeh-Mahani, F | 1 |
| Basiri, M | 1 |
| Nozari, M | 1 |
| Fu, Y | 1 |
| Lei, F | 1 |
| Wang, J | 1 |
| Wang, W | 1 |
| Zheng, Y | 1 |
| Muzyko, EA | 1 |
| Tkacheva, GA | 1 |
| Perfilova, VN | 2 |
| Matvienko, LS | 1 |
| Naumenko, LV | 1 |
| Vasil'eva, OS | 1 |
| Tyurenkov, IN | 2 |
| Lenart, J | 1 |
| Augustyniak, J | 1 |
| Lazarewicz, JW | 1 |
| Zieminska, E | 1 |
| Lu, J | 5 |
| Li, Q | 3 |
| Ma, G | 1 |
| Hong, C | 1 |
| Zhang, W | 1 |
| Wang, Y | 1 |
| Liao, Y | 1 |
| Solmaz, V | 1 |
| Tekatas, A | 1 |
| Erdoğan, MA | 1 |
| Erbaş, O | 1 |
| Mshaty, A | 1 |
| Haijima, A | 1 |
| Takatsuru, Y | 1 |
| Ninomiya, A | 1 |
| Yajima, H | 1 |
| Kokubo, M | 1 |
| Khairinisa, MA | 1 |
| Miyazaki, W | 1 |
| Amano, I | 1 |
| Koibuchi, N | 1 |
| Shang, Y | 1 |
| Chen, R | 1 |
| Li, F | 1 |
| Zhang, H | 1 |
| Zhang, T | 1 |
| Kim, YB | 1 |
| Jung, WW | 1 |
| Lee, SW | 1 |
| Jin, X | 1 |
| Kang, HK | 1 |
| Hong, EH | 1 |
| Min, SS | 1 |
| Kim, YS | 1 |
| Han, HC | 1 |
| Colwell, CS | 1 |
| Kim, YI | 1 |
| Pozzi, D | 1 |
| Rasile, M | 1 |
| Corradini, I | 1 |
| Matteoli, M | 1 |
| Marguet, F | 1 |
| Friocourt, G | 1 |
| Brosolo, M | 1 |
| Sauvestre, F | 1 |
| Marcorelles, P | 1 |
| Lesueur, C | 1 |
| Marret, S | 2 |
| Gonzalez, BJ | 2 |
| Laquerrière, A | 1 |
| Yang, JQ | 1 |
| Yang, CH | 1 |
| Yin, BQ | 1 |
| Singha, SP | 1 |
| Memon, S | 1 |
| Kazi, SAF | 1 |
| Nizamani, GS | 1 |
| Rezazadeh, H | 1 |
| Sharifi, MR | 1 |
| Sharifi, M | 1 |
| Soltani, N | 1 |
| Batra, G | 1 |
| Saini, L | 1 |
| Sharma, S | 1 |
| Singh, A | 1 |
| Singh, RS | 1 |
| Bansal, S | 1 |
| Modi, M | 1 |
| Adamu, HA | 1 |
| Imam, MU | 1 |
| Der-Jiun, O | 1 |
| Ismail, M | 1 |
| Fujáková-Lipski, M | 1 |
| Kaping, D | 1 |
| Šírová, J | 1 |
| Horáček, J | 1 |
| Páleníček, T | 1 |
| Zach, P | 1 |
| Klaschka, J | 1 |
| Kačer, P | 1 |
| Syslová, K | 1 |
| Vrajová, M | 1 |
| Bubenikova-Valešová, V | 1 |
| Beste, C | 1 |
| Šlamberová, R | 4 |
| Dong, W | 1 |
| Zhang, C | 3 |
| Yu, Y | 2 |
| Zhang, Z | 1 |
| Fazeli, W | 1 |
| Zappettini, S | 1 |
| Marguet, SL | 1 |
| Grendel, J | 1 |
| Esclapez, M | 1 |
| Bernard, C | 1 |
| Isbrandt, D | 1 |
| Li, Y | 2 |
| Zhou, Y | 2 |
| Peng, L | 1 |
| Zhao, Y | 1 |
| Coimbra, B | 1 |
| Soares-Cunha, C | 1 |
| Borges, S | 1 |
| Vasconcelos, NA | 1 |
| Sousa, N | 1 |
| Rodrigues, AJ | 1 |
| Hu, D | 1 |
| Cheng, S | 1 |
| Watanabe, Y | 1 |
| Abe, H | 2 |
| Nakajima, K | 2 |
| Ideta-Otsuka, M | 1 |
| Igarashi, K | 1 |
| Woo, GH | 1 |
| Yoshida, T | 3 |
| Shibutani, M | 4 |
| Wollman, LB | 1 |
| Levine, RB | 1 |
| Fregosi, RF | 2 |
| Cunha-Rodrigues, MC | 1 |
| Balduci, CTDN | 1 |
| Tenório, F | 1 |
| Barradas, PC | 1 |
| Masubuchi, Y | 1 |
| Ito, Y | 1 |
| Inohana, M | 1 |
| Takino, M | 1 |
| Saegusa, Y | 1 |
| Sugita-Konishi, Y | 1 |
| Varman, DR | 1 |
| Soria-Ortíz, MB | 1 |
| Martínez-Torres, A | 1 |
| Reyes-Haro, D | 1 |
| Dunn, GA | 1 |
| Nigg, JT | 1 |
| Sullivan, EL | 1 |
| Fontaine, CJ | 1 |
| Pinar, C | 1 |
| Yang, W | 1 |
| Pang, AF | 1 |
| Suesser, KE | 1 |
| Choi, JSJ | 1 |
| Christie, BR | 1 |
| Woerman, AL | 1 |
| Mendelowitz, D | 2 |
| Valenzuela, CF | 3 |
| Puglia, MP | 1 |
| Zucca, S | 1 |
| DuBois, DW | 2 |
| Tobery, AN | 1 |
| Griffith, WH | 1 |
| Brandt, P | 1 |
| Frye, GD | 2 |
| Zhou, R | 2 |
| Chen, F | 1 |
| Chang, F | 1 |
| Bai, Y | 1 |
| Chen, L | 1 |
| Delhaes, F | 1 |
| Fournier, S | 1 |
| Tolsa, JF | 1 |
| Peyter, AC | 1 |
| Bairam, A | 1 |
| Kinkead, R | 1 |
| Aligny, C | 1 |
| Roux, C | 1 |
| Dourmap, N | 1 |
| Ramdani, Y | 1 |
| Do-Rego, JC | 1 |
| Jégou, S | 1 |
| Leroux, P | 1 |
| Leroux-Nicollet, I | 1 |
| Cusmano, DM | 1 |
| Mong, JA | 1 |
| Rideau Batista Novais, A | 1 |
| Crouzin, N | 1 |
| Cavalier, M | 1 |
| Boubal, M | 1 |
| Guiramand, J | 1 |
| Cohen-Solal, C | 1 |
| de Jesus Ferreira, MC | 1 |
| Cambonie, G | 1 |
| Vignes, M | 1 |
| Barbanel, G | 1 |
| Ogi, H | 1 |
| Itoh, K | 1 |
| Ikegaya, H | 1 |
| Fushiki, S | 1 |
| Stansfield, KH | 1 |
| Ruby, KN | 1 |
| Soares, BD | 1 |
| McGlothan, JL | 1 |
| Liu, X | 1 |
| Guilarte, TR | 1 |
| Mikhailova, LI | 1 |
| Zhakupova, GA | 1 |
| Lebedeva, SA | 1 |
| Ehrlich, DE | 1 |
| Neigh, GN | 1 |
| Bourke, CH | 1 |
| Nemeth, CL | 1 |
| Hazra, R | 1 |
| Ryan, SJ | 1 |
| Rowson, S | 1 |
| Jairam, N | 1 |
| Sholar, CA | 1 |
| Rainnie, DG | 1 |
| Stowe, ZN | 1 |
| Owens, MJ | 1 |
| Aoyama, Y | 1 |
| Toriumi, K | 2 |
| Mouri, A | 2 |
| Hattori, T | 1 |
| Ueda, E | 1 |
| Shimato, A | 1 |
| Sakakibara, N | 1 |
| Soh, Y | 1 |
| Mamiya, T | 2 |
| Nagai, T | 1 |
| Kim, HC | 2 |
| Hiramatsu, M | 1 |
| Nabeshima, T | 2 |
| Yamada, K | 1 |
| Saito, F | 1 |
| Tanaka, T | 1 |
| Mizukami, S | 1 |
| Hasegawa-Baba, Y | 1 |
| Imatanaka, N | 1 |
| Akahori, Y | 1 |
| Canetta, S | 1 |
| Bolkan, S | 1 |
| Padilla-Coreano, N | 1 |
| Song, LJ | 1 |
| Sahn, R | 1 |
| Harrison, NL | 1 |
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| Brown, A | 1 |
| Kellendonk, C | 1 |
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| Allan, AM | 2 |
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| Werthammer, J | 1 |
| Boksa, P | 1 |
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| Middleton, FA | 1 |
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| Felipo, V | 1 |
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| Wood, K | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Open Label Study for the Use of Transcranial Ultrasound Treatment of Attention Deficit Hyperactive Disorder[NCT04497363] | 100 participants (Anticipated) | Interventional | 2020-07-01 | Enrolling by invitation | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for gamma-aminobutyric acid and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Environmental regulation of the chloride transporter KCC2: switching inflammation off to switch the GABA on?
Topics: Chlorides; Developmental Disabilities; Female; gamma-Aminobutyric Acid; Humans; Inflammation; Matern | 2020 |
Valproic Acid and Propionic Acid Modulated Mechanical Pathways Associated with Autism Spectrum Disorder at Prenatal and Neonatal Exposure.
Topics: Animals; Autism Spectrum Disorder; Behavior, Animal; Disease Models, Animal; Female; Food Preservati | 2022 |
Neuroinflammation as a risk factor for attention deficit hyperactivity disorder.
Topics: Adolescent; Animals; Attention Deficit Disorder with Hyperactivity; Central Nervous System; Child; C | 2019 |
Focus on: neurotransmitter systems.
Topics: Alcohol Drinking; Animals; Biogenic Amines; Female; Fetal Alcohol Spectrum Disorders; gamma-Aminobut | 2011 |
Epigenetic mediation of environmental influences in major psychotic disorders.
Topics: Alleles; Bipolar Disorder; Child; Child Abuse; Diseases in Twins; DNA Methylation; Epigenesis, Genet | 2009 |
The aryl hydrocarbon receptor pathway and sexual differentiation of neuroendocrine functions.
Topics: Animals; Dioxins; Environmental Exposure; Estradiol; Female; gamma-Aminobutyric Acid; Glutamic Acid; | 2006 |
Benzodiazepines and the developing rat: a critical review.
Topics: Aging; Animals; Animals, Newborn; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepines; Brain; Bra | 1985 |
134 other studies available for gamma-aminobutyric acid and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Postweaning positive modulation of α5GABAA receptors improves autism-like features in prenatal valproate rat model in a sex-specific manner.
Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Behavior, Animal; Calcium; Disease Models, Ani | 2022 |
Size anomaly and alteration of GABAergic enzymes expressions in cerebellum of a valproic acid mouse model of autism.
Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Cerebellum; Disease Models, Animal; Female; ga | 2022 |
The upregulation of glutamate decarboxylase 67 against hippocampal excitability damage in male fetal rats by prenatal caffeine exposure.
Topics: Adenylyl Cyclases; Animals; Brain-Derived Neurotrophic Factor; Caffeine; Colforsin; Female; gamma-Am | 2022 |
Homotaurine ameliorates the core ASD symptomatology in VPA rats through GABAergic signaling: Role of GAD67.
Topics: Animals; Autism Spectrum Disorder; Behavior, Animal; Disease Models, Animal; Female; gamma-Aminobuty | 2022 |
Prenatal, but not postnatal exposure to chlorpyrifos affects social behavior of mice and the excitatory-inhibitory balance in a sex-dependent manner.
Topics: Animals; Behavior, Animal; Chlorpyrifos; Corn Oil; Female; gamma-Aminobutyric Acid; Humans; Male; Mi | 2022 |
The effects of postnatal erythropoietin and nano-erythropoietin on behavioral alterations by mediating K-Cl co-transporter 2 in the valproic acid-induced rat model of autism.
Topics: Animals; Autistic Disorder; Behavior, Animal; Disease Models, Animal; Erythropoietin; Female; gamma- | 2023 |
Maternal cigarette smoke exposure disturbs glutamate/GABA balance in pFRG of neonatal rats.
Topics: Animals; Animals, Newborn; Biological Clocks; Chemoreceptor Cells; Cigarette Smoking; Female; gamma- | 2020 |
Effects of Gaba Derivatives on Anxious and Compulsive Behavior in Offspring of Rats with Experimental Preeclampsia.
Topics: Animals; Animals, Outbred Strains; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Female; GABA Agon | 2020 |
Altered expression of glutamatergic and GABAergic genes in the valproic acid-induced rat model of autism: A screening test.
Topics: Animals; Autistic Disorder; Cerebellum; Cerebral Cortex; Female; GABA Agents; gamma-Aminobutyric Aci | 2020 |
Prenatal ethanol exposure-induced hypothalamic an imbalance of glutamatergic/GABAergic projections and low functional expression in male offspring rats.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Ethanol; Female; Fetal Weight; GABAergic Neuro | 2020 |
Programming of a developmental imbalance in hypothalamic glutamatergic/GABAergic afferents mediates low basal activity of the hypothalamic-pituitary-adrenal axis induced by prenatal dexamethasone exposure in male offspring rats.
Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Arginine Vasopressin; Corticosterone; Dexame | 2020 |
Exenatide, a GLP-1 analog, has healing effects on LPS-induced autism model: Inflammation, oxidative stress, gliosis, cerebral GABA, and serotonin interactions.
Topics: Animals; Autistic Disorder; Cerebral Cortex; Exenatide; Female; gamma-Aminobutyric Acid; Inflammatio | 2020 |
Neurotoxic effects of lactational exposure to perfluorooctane sulfonate on learning and memory in adult male mouse.
Topics: Alkanesulfonic Acids; Animals; Female; Fluorocarbons; gamma-Aminobutyric Acid; Glutamic Acid; Hippoc | 2020 |
Prenatal stress impairs memory function in the early development of male-offspring associated with the gaba function.
Topics: Animals; Female; gamma-Aminobutyric Acid; Hippocampus; Male; Memory; Neuronal Plasticity; Pregnancy; | 2021 |
Excessive maternal salt intake gives rise to vasopressin-dependent salt sensitivity of blood pressure in male offspring.
Topics: Animals; Benzazepines; Blood Pressure; Female; gamma-Aminobutyric Acid; Lactation; Male; Neurons; Pr | 2021 |
Prenatal alcohol exposure is a leading cause of interneuronopathy in humans.
Topics: Alcohol Drinking; Alcoholism; Binge Drinking; Brain; Calbindin 2; Case-Control Studies; Cell Movemen | 2020 |
Combined the GABA-A and GABA-B receptor agonists attenuates autistic behaviors in a prenatal valproic acid-induced mouse model of autism.
Topics: Animals; Anticonvulsants; Autism Spectrum Disorder; Behavior, Animal; Disease Models, Animal; Drug T | 2021 |
Gamma aminobutyric acid signaling disturbances and altered astrocytic morphology associated with Bisphenol A induced cognitive impairments in rat offspring.
Topics: Animals; Astrocytes; Benzhydryl Compounds; Cognitive Dysfunction; Female; gamma-Aminobutyric Acid; P | 2021 |
Gamma-aminobutyric acid attenuates insulin resistance in type 2 diabetic patients and reduces the risk of insulin resistance in their offspring.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Female; GABA Agents; gamma-Aminobutyric Acid; Hum | 2021 |
In utero Exposure to Germinated Brown Rice and Its GABA Extract Attenuates High-Fat-Diet-Induced Insulin Resistance in Rat Offspring.
Topics: Animals; Diet, High-Fat; Female; gamma-Aminobutyric Acid; Germination; Insulin Resistance; Interleuk | 2017 |
Trans-generational neurochemical modulation of methamphetamine in the adult brain of the Wistar rat.
Topics: Animals; Brain; Dopamine; Female; gamma-Aminobutyric Acid; Glutamic Acid; Methamphetamine; Pregnancy | 2017 |
Prenatal nicotine exposure induces HPA axis-hypersensitivity in offspring rats via the intrauterine programming of up-regulation of hippocampal GAD67.
Topics: Adrenocorticotropic Hormone; Animals; Birth Weight; Corticosterone; DNA (Cytosine-5-)-Methyltransfer | 2017 |
Early-life exposure to caffeine affects the construction and activity of cortical networks in mice.
Topics: Animals; Animals, Newborn; Caffeine; Central Nervous System Stimulants; Cerebral Cortex; Dendrites; | 2017 |
Reduced protein expressions of cytomembrane GABA
Topics: Animals; Autism Spectrum Disorder; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; | 2017 |
Impairments in laterodorsal tegmentum to VTA projections underlie glucocorticoid-triggered reward deficits.
Topics: Animals; Cognitive Dysfunction; Dexamethasone; Dopamine; Female; gamma-Aminobutyric Acid; Glucocorti | 2017 |
High expression of hippocampal glutamic acid decarboxylase 67 mediates hypersensitivity of the hypothalamic-pituitary-adrenal axis in response to prenatal caffeine exposure in rats.
Topics: Adrenocorticotropic Hormone; Animals; Caffeine; Cells, Cultured; Corticosterone; Female; gamma-Amino | 2018 |
Aberrant Epigenetic Gene Regulation in GABAergic Interneuron Subpopulations in the Hippocampal Dentate Gyrus of Mouse Offspring Following Developmental Exposure to Hexachlorophene.
Topics: Animals; Animals, Newborn; Dentate Gyrus; Epigenesis, Genetic; Female; GABAergic Neurons; gamma-Amin | 2018 |
Developmental plasticity of GABAergic neurotransmission to brainstem motoneurons.
Topics: Animals; Animals, Newborn; Brain Stem; Female; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Pote | 2018 |
GABA function may be related to the impairment of learning and memory caused by systemic prenatal hypoxia-ischemia.
Topics: Animals; Female; gamma-Aminobutyric Acid; Hippocampus; Hypoxia-Ischemia, Brain; Learning; Maze Learn | 2018 |
Programming for increased expression of hippocampal GAD67 mediated the hypersensitivity of the hypothalamic-pituitary-adrenal axis in male offspring rats with prenatal ethanol exposure.
Topics: Animals; Cell Line; Ethanol; Female; Fetus; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippoc | 2018 |
Developmental exposure of citreoviridin transiently affects hippocampal neurogenesis targeting multiple regulatory functions in mice.
Topics: Animals; Apoptosis; Aurovertins; Brain-Derived Neurotrophic Factor; Cell Proliferation; Dose-Respons | 2018 |
GABAρ3 expression in lobule X of the cerebellum is reduced in the valproate model of autism.
Topics: Animals; Autism Spectrum Disorder; Behavior, Animal; Cerebellum; Disease Models, Animal; Female; gam | 2018 |
Impaired Bidirectional Synaptic Plasticity in Juvenile Offspring Following Prenatal Ethanol Exposure.
Topics: Animals; Bicuculline; Body Weight; Dentate Gyrus; Female; Fetal Alcohol Spectrum Disorders; GABA Ant | 2019 |
Perinatal sulfur dioxide exposure alters brainstem parasympathetic control of heart rate.
Topics: Animals; Animals, Newborn; Brain Stem; Diving; Environmental Pollutants; Female; gamma-Aminobutyric | 2013 |
Long-lasting distortion of GABA signaling in MS/DB neurons after binge-like ethanol exposure during initial synaptogenesis.
Topics: Animals; Animals, Newborn; Binge Drinking; Central Nervous System Depressants; Diagonal Band of Broc | 2013 |
Persistent overexpression of DNA methyltransferase 1 attenuating GABAergic inhibition in basolateral amygdala accounts for anxiety in rat offspring exposed perinatally to low-dose bisphenol A.
Topics: Air Pollutants, Occupational; Amygdala; Animals; Anxiety; Benzhydryl Compounds; Disease Models, Anim | 2013 |
Consequences of gestational stress on GABAergic modulation of respiratory activity in developing newborn pups.
Topics: Animals; Animals, Newborn; Brain Stem; Cervical Vertebrae; Dose-Response Relationship, Drug; Female; | 2014 |
Ketamine alters cortical integration of GABAergic interneurons and induces long-term sex-dependent impairments in transgenic Gad67-GFP mice.
Topics: Animals; Apoptosis; Calcium; Cell Differentiation; Cerebral Cortex; Female; gamma-Aminobutyric Acid; | 2014 |
In utero exposure to valproic acid changes sleep in juvenile rats: a model for sleep disturbances in autism.
Topics: Aging; Animals; Arousal; Child Development Disorders, Pervasive; Circadian Rhythm; Disease Models, A | 2014 |
Tiagabine improves hippocampal long-term depression in rat pups subjected to prenatal inflammation.
Topics: Animals; Child Development Disorders, Pervasive; Female; GABAergic Neurons; gamma-Aminobutyric Acid; | 2014 |
Alterations of neurotransmitter norepinephrine and gamma-aminobutyric acid correlate with murine behavioral perturbations related to bisphenol A exposure.
Topics: Animals; Behavior, Animal; Benzhydryl Compounds; Female; gamma-Aminobutyric Acid; Glutamic Acid; Lac | 2015 |
Early-life lead exposure recapitulates the selective loss of parvalbumin-positive GABAergic interneurons and subcortical dopamine system hyperactivity present in schizophrenia.
Topics: Animals; Blotting, Western; Brain; Chromatography, High Pressure Liquid; Dopamine; Female; gamma-Ami | 2015 |
[Comparative study of the effects of new neuroactive amino acid derivatives on the postnatal development of the rat's offspring with experimental preeclampsia].
Topics: Animals; Animals, Newborn; Behavior, Animal; Cognition; Disease Models, Animal; Female; gamma-Aminob | 2014 |
Prenatal stress, regardless of concurrent escitalopram treatment, alters behavior and amygdala gene expression of adolescent female rats.
Topics: Amygdala; Animals; Anxiety; Citalopram; Corticosterone; Disease Models, Animal; Estradiol; Female; g | 2015 |
Prenatal Nicotine Exposure Impairs the Proliferation of Neuronal Progenitors, Leading to Fewer Glutamatergic Neurons in the Medial Prefrontal Cortex.
Topics: Animals; Cell Cycle; Cell Movement; Cognition Disorders; Disease Models, Animal; Female; gamma-Amino | 2016 |
Developmental cuprizone exposure impairs oligodendrocyte lineages differentially in cortical and white matter tissues and suppresses glutamatergic neurogenesis signals and synaptic plasticity in the hippocampal dentate gyrus of rats.
Topics: Animals; Animals, Newborn; Apoptosis; Cell Lineage; Cuprizone; Dentate Gyrus; Down-Regulation; Femal | 2016 |
Maternal immune activation leads to selective functional deficits in offspring parvalbumin interneurons.
Topics: Animals; Disease Models, Animal; Female; GABAergic Neurons; gamma-Aminobutyric Acid; Humans; Immunit | 2016 |
Prenatal alcohol exposure alters synaptic activity of adult hippocampal dentate granule cells under conditions of enriched environment.
Topics: Animals; Dentate Gyrus; Disease Models, Animal; Environment; Ethanol; Female; Fetal Alcohol Spectrum | 2016 |
Prenatal phencyclidine treatment induces behavioral deficits through impairment of GABAergic interneurons in the prefrontal cortex.
Topics: Animals; Behavior, Animal; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Gluta | 2016 |
Exposure of mother rats to chronic unpredictable stress before pregnancy alters the metabolism of gamma-aminobutyric acid and glutamate in the right hippocampus of offspring in early adolescence in a sexually dimorphic manner.
Topics: Animals; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Mothers; Pregnancy; Pren | 2016 |
The effects of prenatal H1N1 infection at E16 on FMRP, glutamate, GABA, and reelin signaling systems in developing murine cerebellum.
Topics: Age Factors; Animals; Cell Adhesion Molecules, Neuronal; Cerebellum; Extracellular Matrix Proteins; | 2017 |
An Atypical Withdrawal Syndrome in Neonates Prenatally Exposed to Gabapentin and Opioids.
Topics: Amines; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid | 2017 |
Early Development of Parvalbumin-, Somatostatin-, and Cholecystokinin-Expressing Neurons in Rat Brain following Prenatal Immune Activation and Maternal Iron Deficiency.
Topics: Animals; Brain; Cholecystokinin; Dopamine; Female; gamma-Aminobutyric Acid; Iron Deficiencies; Neuro | 2016 |
Moderate perinatal arsenic exposure alters neuroendocrine markers associated with depression and increases depressive-like behaviors in adult mouse offspring.
Topics: Analysis of Variance; Animals; Animals, Newborn; Arsenic; Behavior, Animal; Corticosterone; Depressi | 2008 |
Prenatal immune activation leads to multiple changes in basal neurotransmitter levels in the adult brain: implications for brain disorders of neurodevelopmental origin such as schizophrenia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Brain Diseases; Chromatography, High Press | 2009 |
Gestational ethanol exposure alters the behavioral response to ethanol odor and the expression of neurotransmission genes in the olfactory bulb of adolescent rats.
Topics: Alcohol Drinking; Animals; Behavior, Animal; Ethanol; Female; Fetus; gamma-Aminobutyric Acid; Gene E | 2009 |
Impaired in vivo synaptic plasticity in dentate gyrus and spatial memory in juvenile rats induced by prenatal morphine exposure.
Topics: Action Potentials; Animals; Cell Death; Dentate Gyrus; Excitatory Postsynaptic Potentials; Female; g | 2009 |
Neural basis of psychosis-related behaviour in the infection model of schizophrenia.
Topics: Animals; Avoidance Learning; Brain; Disease Models, Animal; Dopamine; Female; gamma-Aminobutyric Aci | 2009 |
Effect of gabapentin on cognitive processes in rats not exposed and exposed to tobacco smoke during fetal life.
Topics: Amines; Animals; Anticonvulsants; Antidepressive Agents; Behavior, Animal; Cognition; Cyclohexanecar | 2008 |
Impact of 4-methylbenzylidene-camphor (4-MBC) during embryonic and fetal development in the neuroendocrine regulation of testicular axis in prepubertal and peripubertal male rats.
Topics: Analysis of Variance; Animals; Aspartic Acid; Camphor; Chromatography, High Pressure Liquid; Dose-Re | 2009 |
Impact of ethanol on the developing GABAergic system.
Topics: Alcohol-Induced Disorders, Nervous System; Animals; Cell Movement; Cell Proliferation; Central Nervo | 2009 |
Developmental exposure to polychlorinated biphenyls 52, 138 or 180 affects differentially learning or motor coordination in adult rats. Mechanisms involved.
Topics: Animals; Cerebellum; Cyclic GMP; Discrimination, Psychological; Environmental Pollutants; Extracellu | 2010 |
Prenatal nicotine exposure increases GABA signaling and mucin expression in airway epithelium.
Topics: Animals; Base Sequence; Bronchi; Cells, Cultured; DNA Primers; Epithelial Cells; Female; gamma-Amino | 2011 |
Densities of glutamatergic and GABAergic presynaptic terminals are altered in experimental cortical dysplasia.
Topics: Analysis of Variance; Animals; Animals, Newborn; Cerebral Cortex; Disease Models, Animal; Embryo, Ma | 2010 |
Effect of cross-fostering on seizures in adult male offspring of methamphetamine-treated rat mothers.
Topics: Amphetamine-Related Disorders; Animals; Female; gamma-Aminobutyric Acid; Male; Maternal Behavior; Me | 2010 |
Impact of gestational and lactational phthalate exposure on hypothalamic content of amino acid neurotransmitters and FSH secretion in peripubertal male rats.
Topics: Amino Acids; Animals; Aspartic Acid; Diethylhexyl Phthalate; Female; Follicle Stimulating Hormone; g | 2010 |
Prenatal ethanol exposure attenuates GABAergic inhibition in basolateral amygdala leading to neuronal hyperexcitability and anxiety-like behavior of adult rat offspring.
Topics: Amygdala; Animals; Anxiety; Cornified Envelope Proline-Rich Proteins; Disease Models, Animal; Ethano | 2010 |
Late prenatal immune activation in mice leads to behavioral and neurochemical abnormalities relevant to the negative symptoms of schizophrenia.
Topics: Animals; Behavior, Animal; Central Nervous System Viral Diseases; Disease Models, Animal; Dopamine; | 2010 |
Prenatal exposure of ethanol induces increased glutamatergic neuronal differentiation of neural progenitor cells.
Topics: Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; Ethanol; Eye Proteins; Female; F | 2010 |
Rats exposed to isoflurane in utero during early gestation are behaviorally abnormal as adults.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Anxiety; Behavior, Animal; Blood Pressure; Body Weight | 2011 |
Developmental GABAergic deficit enhances methamphetamine-induced apoptosis.
Topics: Animals; Apoptosis; Central Nervous System Stimulants; Disease Models, Animal; Dizocilpine Maleate; | 2011 |
Probable gamma-aminobutyric acid involvement in bisphenol A effect at the hypothalamic level in adult male rats.
Topics: Animals; Benzhydryl Compounds; Female; Follicle Stimulating Hormone; gamma-Aminobutyric Acid; Gonado | 2011 |
Cocaine alters BDNF expression and neuronal migration in the embryonic mouse forebrain.
Topics: Age Factors; Animals; Brain-Derived Neurotrophic Factor; Cell Death; Cell Movement; Cocaine; DNA-Bin | 2011 |
Different effects by sex on hypothalamic-pituitary axis of prepubertal offspring rats produced by in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP).
Topics: Animals; Aspartic Acid; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Female; Follicle S | 2012 |
Similar distribution changes of GABAergic interneuron subpopulations in contrast to the different impact on neurogenesis between developmental and adult-stage hypothyroidism in the hippocampal dentate gyrus in rats.
Topics: Age Factors; Animals; Antithyroid Agents; Apoptosis; Cell Proliferation; Dentate Gyrus; Dose-Respons | 2012 |
Prenatal cocaine exposure decreases parvalbumin-immunoreactive neurons and GABA-to-projection neuron ratio in the medial prefrontal cortex.
Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Female; gamma-Aminobutyric Acid; Male; Mice; Mice, Tra | 2012 |
Prenatal immune activation induces maturation-dependent alterations in the prefrontal GABAergic transcriptome.
Topics: Age Factors; Animals; Behavior, Animal; Disease Models, Animal; Female; GABAergic Neurons; gamma-Ami | 2014 |
Heterotopic neurons with altered inhibitory synaptic function in an animal model of malformation-associated epilepsy.
Topics: Animals; Carrier Proteins; Choristoma; Disease Models, Animal; Epilepsy; Female; GABA Plasma Membran | 2002 |
Effects of 8-OH-DPAT on open field performance of young and aged rats prenatally exposed to diazepam: a tool to reveal 5-HT1A receptor function.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Anti-Anxiety Agents; Behavior, Animal; Diaze | 2003 |
Axo-axonic structures in the medial prefrontal cortex of the rat: reduction by prenatal exposure to cocaine.
Topics: Animals; Axons; Carrier Proteins; Cell Count; Cocaine; Cognition Disorders; Dopamine Uptake Inhibito | 2003 |
Prenatal protein malnutrition results in increased frequency of miniature inhibitory postsynaptic currents in rat CA3 interneurons.
Topics: Action Potentials; Animals; Caseins; Dietary Proteins; Electric Conductivity; Female; GABA Agonists; | 2003 |
Perinatal iron deficiency alters the neurochemical profile of the developing rat hippocampus.
Topics: Aging; Animals; Aspartic Acid; Body Weight; Brain; Brain Chemistry; Creatine; Ethanolamines; Female; | 2003 |
Chronic prenatal ethanol exposure impairs conditioned responding and enhances GABA release in the hippocampus of the adult guinea pig.
Topics: Animals; Biological Transport; Central Nervous System Depressants; Conditioning, Psychological; Etha | 2004 |
Altered synaptic activities in cultures of neocortical neurons from prenatally X-irradiated rats.
Topics: Action Potentials; Animals; Biomarkers; Cell Death; Cells, Cultured; Coculture Techniques; Female; F | 2004 |
Role of maternal adrenal glands on the developing serotoninergic and aminoacidergic systems of the postnatal rat brain.
Topics: Adrenal Glands; Adrenalectomy; Animals; Brain; Down-Regulation; Female; gamma-Aminobutyric Acid; Glu | 2004 |
Prenatal androgens alter GABAergic drive to gonadotropin-releasing hormone neurons: implications for a common fertility disorder.
Topics: Androgens; Animals; Estrous Cycle; Female; gamma-Aminobutyric Acid; Gonadal Steroid Hormones; Gonado | 2004 |
Binge ethanol exposure delays development of GABAergic miniature postsynaptic currents in septal neurons.
Topics: Alcohol-Induced Disorders, Nervous System; Animals; Cell Differentiation; Cells, Cultured; Central N | 2004 |
Prenatal nicotine exposure alters central cardiorespiratory responses to hypoxia in rats: implications for sudden infant death syndrome.
Topics: Action Potentials; Animals; Autonomic Fibers, Preganglionic; Female; gamma-Aminobutyric Acid; Glycin | 2004 |
The GABAergic system of the developing neocortex has a reduced capacity to recover from in utero injury in experimental cortical dysplasia.
Topics: Animals; Animals, Newborn; Brain Injuries; Cell Count; Embryo, Mammalian; Female; gamma-Aminobutyric | 2004 |
Serum glutamic acid decarboxylase 65 antibody levels in people with schizophrenia and their families.
Topics: Antibodies; Central Nervous System; Coxsackievirus Infections; Diabetes Mellitus, Type 1; Female; Fe | 2005 |
Maternal exposure to the antiepileptic drug vigabatrin affects postnatal development in the rat.
Topics: Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Birth Weight; Body Weight; Brain Chemi | 2005 |
Alcohol is a potent stimulant of immature neuronal networks: implications for fetal alcohol spectrum disorder.
Topics: Alcohol-Induced Disorders, Nervous System; Animals; Animals, Newborn; Calcium Signaling; Central Ner | 2005 |
Remodeling of hippocampal GABAergic system in adult offspring after maternal hypoxia and magnesium sulfate load: immunohistochemical study.
Topics: Animals; Brain Injuries; Calbindins; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippo | 2005 |
Transient maternal hypothyroxinemia at onset of corticogenesis alters tangential migration of medial ganglionic eminence-derived neurons.
Topics: Animals; Brain Mapping; Calbindins; Cell Count; Cell Movement; Cells, Cultured; Cerebral Cortex; Emb | 2005 |
Chronic prenatal ethanol exposure alters glucocorticoid signalling in the hippocampus of the postnatal Guinea pig.
Topics: Amniotic Fluid; Animals; Animals, Newborn; Central Nervous System Depressants; Circadian Rhythm; Eth | 2005 |
Glutamic acid decarboxylase and GABA immunoreactivities in the cerebellar cortex of adult rat after prenatal exposure to a low concentration of carbon monoxide.
Topics: Animals; Carbon Monoxide; Carboxyhemoglobin; Cerebellar Cortex; Coloring Agents; Cytoplasmic Granule | 2005 |
Endogenous gamma-aminobutyric acid can excite gonadotropin-releasing hormone neurons.
Topics: Action Potentials; Androgens; Animals; Diestrus; Dihydrotestosterone; Electrophysiology; Excitatory | 2005 |
Effects of prenatal paraquat and mancozeb exposure on amino acid synaptic transmission in developing mouse cerebellar cortex.
Topics: Animals; Aspartic Acid; Cerebellar Cortex; Disease Models, Animal; Down-Regulation; Female; Fungicid | 2005 |
Cholinergic modulation of appetite-related synapses in mouse lateral hypothalamic slice.
Topics: Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Animals, Newborn; Appetite; Choline | 2005 |
Region-, age-, and sex-specific effects of fetal diazepam exposure on the postnatal development of neurosteroids.
Topics: Animals; Brain; Chlorides; Diazepam; Female; gamma-Aminobutyric Acid; Pregnancy; Prenatal Exposure D | 2006 |
Effect of prenatal exposure to ethanol on glutamate and GABA immunoreactivity in macaque somatosensory and motor cortices: critical timing of exposure.
Topics: Animals; Cell Count; Central Nervous System Depressants; Ethanol; Female; Fetal Alcohol Spectrum Dis | 2006 |
Microanatomy in 21 day rat brains exposed prenatally to cocaine.
Topics: Animals; Brain; Cell Differentiation; Cocaine; Cocaine-Related Disorders; Dendrites; Disease Models, | 2006 |
Prenatal stress and early adoption effects on benzodiazepine receptors and anxiogenic behavior in the adult rat brain.
Topics: Aging; Amygdala; Animals; Animals, Newborn; Anxiety Disorders; Binding Sites; Brain; Down-Regulation | 2006 |
Prenatal nicotine exposure alters glycinergic and GABAergic control of respiratory frequency in the neonatal rat brainstem-spinal cord preparation.
Topics: Analysis of Variance; Animals; Animals, Newborn; Brain Stem; Drug Interactions; Female; gamma-Aminob | 2007 |
Prenatal exposure to an NMDA receptor antagonist, MK-801 reduces density of parvalbumin-immunoreactive GABAergic neurons in the medial prefrontal cortex and enhances phencyclidine-induced hyperlocomotion but not behavioral sensitization to methamphetamine
Topics: Age Factors; Animals; Behavior, Animal; Central Nervous System Stimulants; Disease Models, Animal; D | 2007 |
Prenatal exposure to valproic acid disturbs the enkephalinergic system functioning, basal hedonic tone, and emotional responses in an animal model of autism.
Topics: Animals; Anticonvulsants; Anxiety; Autistic Disorder; Basal Ganglia; Conditioning, Classical; Diseas | 2007 |
Effects of prenatal exposure to the CB-1 receptor agonist WIN 55212-2 or CO on the GABAergic neuronal systems of rat cerebellar cortex.
Topics: Animals; Atmosphere Exposure Chambers; Benzoxazines; Birth Weight; Body Weight; Carbon Monoxide; Cer | 2007 |
Adult brain and behavioral pathological markers of prenatal immune challenge during early/middle and late fetal development in mice.
Topics: Acoustic Stimulation; Age Factors; Amphetamines; Animals; Autistic Disorder; Brain; Cell Adhesion Mo | 2008 |
Alteration of the morphology and neurochemistry of the developing mammalian nervous system by hydrogen sulphide.
Topics: Animals; Aspartic Acid; Brain; Cerebellum; Chromatography, High Pressure Liquid; Embryonic and Fetal | 1995 |
Prenatal lorazepam exposure: 4. Persistent alterations in pentylenetetrazole-induced seizure threshold and GABA-dependent chloride uptake after prenatal lorazepam exposure.
Topics: Animals; Brain Chemistry; Chlorides; Chlorine; Female; gamma-Aminobutyric Acid; Lorazepam; Mice; Mus | 1995 |
Intrauterine cocaine exposure of rabbits: persistent elevation of GABA-immunoreactive neurons in anterior cingulate cortex but not visual cortex.
Topics: Animals; Cell Count; Cocaine; Female; gamma-Aminobutyric Acid; Gyrus Cinguli; Immunohistochemistry; | 1995 |
Spatial learning in rats exposed to acute ethanol intoxication on gestational day 8.
Topics: Alcoholic Intoxication; Animals; Female; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Male; Maze | 1996 |
Presynaptic glutamatergic function in dentate gyrus in vivo is diminished by chronic exposure to inorganic lead.
Topics: Animals; Animals, Newborn; Animals, Suckling; Calcium; Dentate Gyrus; Dizocilpine Maleate; Electric | 1996 |
Prenatal ethanol exposure reduces parvalbumin-immunoreactive GABAergic neuronal number in the adult rat cingulate cortex.
Topics: Animals; Cell Count; Ethanol; Female; gamma-Aminobutyric Acid; Gyrus Cinguli; Immunohistochemistry; | 1998 |
Prenatal stress reduces the effectiveness of the neurosteroid 3 alpha,5 alpha-THP to block kainic-acid-induced seizures.
Topics: Analysis of Variance; Animals; Anticonvulsants; Corticosterone; Female; gamma-Aminobutyric Acid; Hip | 1999 |
Influence of fetal alcohol exposure on the GABAergic regulation of growth hormone release in postnatal rats.
Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Body Weight; Central Nervous System Depressants | 1999 |
Prenatal morphine exposure alters susceptibility to bicuculline seizures in a sex- and age-specific manner.
Topics: Age Factors; Analgesics, Opioid; Animals; Bicuculline; Convulsants; Disease Susceptibility; Epilepsy | 2000 |
Prenatal protein malnutrition results in increased frequency of miniature inhibitory synaptic currents in rat CA1 pyramidal cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animal Nutritional Physiological | 2000 |
Viral infection of developing GABAergic neurons in a model of hippocampal disinhibition.
Topics: Animals; Central Nervous System Viral Diseases; Dentate Gyrus; Disease Models, Animal; Epilepsy, Tem | 2000 |
Neurotoxicological outcomes of perinatal heptachlor exposure in the rat.
Topics: Animals; Animals, Newborn; Behavior, Animal; Body Weight; Brain; Brain Chemistry; Chlorides; Embryon | 2001 |
GABA promotes survival but not proliferation of parvalbumin-immunoreactive interneurons in rodent neostriatum: an in vivo study with stereology.
Topics: Animals; Animals, Newborn; Bicuculline; Cell Count; Cell Division; Cell Movement; Cell Survival; Emb | 2001 |
Identification of a sensitive period of prenatal cocaine exposure that alters the development of the anterior cingulate cortex.
Topics: Animals; Cerebral Cortex; Cocaine; Dendrites; Dopamine Uptake Inhibitors; Female; gamma-Aminobutyric | 2001 |
Prenatal cocaine exposure produces consistent developmental alterations in dopamine-rich regions of the cerebral cortex.
Topics: Animals; Animals, Newborn; Axons; Cerebral Cortex; Cocaine; Cocaine-Related Disorders; Dendrites; Do | 2001 |
[The effect of gamma-aminobutyric acid injected into lateral brain ventricle of rats after prenatal cadmium intoxication on flash visual evoked potentials (FVEP)].
Topics: Animals; Cadmium; Cerebral Ventricles; Evoked Potentials, Visual; Female; gamma-Aminobutyric Acid; I | 2001 |
Effects of pre- and postnatal corticosterone exposure on the rat hippocampal GABA system.
Topics: Animals; Anti-Inflammatory Agents; Corticosterone; Female; gamma-Aminobutyric Acid; Gene Expression; | 2001 |
Prenatal morphine exposure decreases susceptibility of adult male rat offspring to bicuculline seizures.
Topics: Animals; Bicuculline; Brain; Disease Susceptibility; Epilepsy; Female; GABA Antagonists; gamma-Amino | 2001 |
Sexually dimorphic influence of prenatal exposure to diazepam on behavioral responses to environmental challenge and on gamma-aminobutyric acid (GABA)-stimulated chloride uptake in the brain.
Topics: Animals; Behavior, Animal; Benzodiazepines; Brain; Cerebral Cortex; Chloride Channels; Chlorides; Di | 1991 |
Regional alterations of brain biogenic amines and GABA/glutamate levels in rats following chronic lead exposure during neonatal development.
Topics: Animals; Biogenic Amines; Body Weight; Brain; Dopamine; Dose-Response Relationship, Drug; Female; ga | 1990 |
Regionally specific alterations in the low-affinity GABAA receptor following perinatal exposure to diazepam.
Topics: Animals; Bicuculline; Binding, Competitive; Brain; Diazepam; Female; gamma-Aminobutyric Acid; Pregna | 1990 |
Operant behavior and reactivity to the anticonflict effect of diazepam in perinatally undernourished rats.
Topics: Animals; Behavior, Animal; Conditioning, Operant; Conflict, Psychological; Diazepam; Female; gamma-A | 1988 |
Some long-lasting neurochemical effects of prenatal or early postnatal exposure to diazepam.
Topics: Aging; Animals; Brain; Choline; Diazepam; Female; Frontal Lobe; gamma-Aminobutyric Acid; Hippocampus | 1985 |
Effects of prenatal phenobarbital on benzodiazepine receptor development.
Topics: Animals; Brain; Cerebellum; Diencephalon; Female; Flunitrazepam; gamma-Aminobutyric Acid; Male; Mice | 1986 |
Effects of prenatal exposure to 2,4-D/2,4,5-T mixture on postnatal changes in rat brain glutamate, GABA, protein, and nucleic acid levels.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; Brain Chemistry; Female; | 1988 |
Effect of pre- and postnatal alcohol consumption on GABA levels of various brain regions in the rat offspring.
Topics: Animals; Body Weight; Brain; Brain Chemistry; Disease Models, Animal; Ethanol; Female; Fetal Alcohol | 1988 |