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gamma-aminobutyric acid and Deficiency, Thiamine

gamma-aminobutyric acid has been researched along with Deficiency, Thiamine in 13 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Research Excerpts

ExcerptRelevanceReference
"Maternal thiamine deficiency causes changes in cellular energy metabolism that can interfere with offspring brain development."3.76Maternal thiamine restriction during lactation induces cognitive impairments and changes in glutamate and GABA concentrations in brain of rat offspring. ( de Freitas-Silva, DM; Franco, GC; Pereira, SR; Resende, Lde S; Ribeiro, AM, 2010)
" In Wernicke-Korsakoff's syndrome (WKS) and the animal model of the disorder, pyrithiamine-induced thiamine deficiency (PTD), there is both diencephalic damage and basal forebrain cell loss that could contribute to the amnesic state."3.75The role of cholinergic and GABAergic medial septal/diagonal band cell populations in the emergence of diencephalic amnesia. ( Roland, JJ; Savage, LM, 2009)
"Thiamine deficiency is a recognized cause of Wernicke's encephalopathy (WE), a condition in which small necrotic lesions are found in close proximity to the third and fourth ventricles and the Sylvian aqueduct."2.40Wernicke's encephalopathy: an excitotoxicity hypothesis. ( McEntee, WJ, 1997)
" Neurons in the thiamine-deficient animals were more sensitive to the inhibitory effects of 5-HT, as demonstrated by a significant parallel shift to the left of the dose-response curve."1.27Enhanced sensitivity of cerebellar Purkinje cells to iontophoretically-applied serotonin in thiamine deficiency. ( Lee, RS; Strahlendorf, HK; Strahlendorf, JC, 1985)
"Thiamine-deficient encephalopathy in the rat is characterized by ataxic gait, loss of righting reflex and curvature of the spine."1.26Amino acid changes in thiamine-deficient encephalopathy: some implications for the pathogenesis of Friedreich's ataxia. ( Barbeau, A; Butterworth, RF; Hamel, E; Landreville, F, 1979)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's3 (23.08)18.2507
2000's2 (15.38)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ferreira-Vieira, TH1
de Freitas-Silva, DM2
Ribeiro, AF1
Pereira, SR2
Ribeiro, ÂM2
Roland, JJ1
Savage, LM1
Bunik, VI1
Fernie, AR1
Resende, Lde S1
Franco, GC1
MONFOORT, CH1
Dodd, PR1
Thomas, GJ1
McCloskey, A1
Crane, DI1
Smith, ID1
McEntee, WJ1
Fadda, F1
Rossetti, ZL1
Hamel, E2
Butterworth, RF2
Barbeau, A2
Landreville, F1
Chan, AW1
Page, MG1
Ankoma-Sey, V1
Coulson, WF1
Bender, DA1
Lee, RS1
Strahlendorf, HK1
Strahlendorf, JC1

Reviews

3 reviews available for gamma-aminobutyric acid and Deficiency, Thiamine

ArticleYear
Metabolic control exerted by the 2-oxoglutarate dehydrogenase reaction: a cross-kingdom comparison of the crossroad between energy production and nitrogen assimilation.
    The Biochemical journal, 2009, Aug-27, Volume: 422, Issue:3

    Topics: Animals; Energy Metabolism; gamma-Aminobutyric Acid; Humans; Ketoglutarate Dehydrogenase Complex; Ke

2009
Wernicke's encephalopathy: an excitotoxicity hypothesis.
    Metabolic brain disease, 1997, Volume: 12, Issue:3

    Topics: Animals; Brain; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Models, Neurological; Neurotoxins; T

1997
Chronic ethanol consumption: from neuroadaptation to neurodegeneration.
    Progress in neurobiology, 1998, Volume: 56, Issue:4

    Topics: Acetylcholine; Adaptation, Physiological; Alcohol Amnestic Disorder; Alcohol Drinking; Alcohol-Relat

1998

Other Studies

10 other studies available for gamma-aminobutyric acid and Deficiency, Thiamine

ArticleYear
Perinatal thiamine restriction affects central GABA and glutamate concentrations and motor behavior of adult rat offspring.
    Neuroscience letters, 2016, Mar-23, Volume: 617

    Topics: Animals; Brain; Cerebellar Cortex; Female; gamma-Aminobutyric Acid; Glutamic Acid; Maternal-Fetal Ex

2016
The role of cholinergic and GABAergic medial septal/diagonal band cell populations in the emergence of diencephalic amnesia.
    Neuroscience, 2009, Apr-21, Volume: 160, Issue:1

    Topics: Acetylcholine; Amnesia; Animals; Brain; Calbindins; Cell Death; Choline O-Acetyltransferase; Disease

2009
Maternal thiamine restriction during lactation induces cognitive impairments and changes in glutamate and GABA concentrations in brain of rat offspring.
    Behavioural brain research, 2010, Jul-29, Volume: 211, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Suckling; Brain; Cognition Disorders; Energy Metabolism; Fem

2010
Restoration of acetoin and succinic semialdehyde formation in pigeon muscle homogenates impaired by thiamine deficiency.
    Biochimica et biophysica acta, 1954, Volume: 14, Issue:2

    Topics: Acetoin; Animals; Columbidae; gamma-Aminobutyric Acid; Ketones; Muscles; Succinates; Thiamine; Thiam

1954
The neurochemical pathology of thiamine deficiency: GABAA and glutamateNMDA receptor binding sites in a goat model.
    Metabolic brain disease, 1996, Volume: 11, Issue:1

    Topics: Alcoholism; Amprolium; Animals; Brain Chemistry; Diazepam; Disease Models, Animal; Dizocilpine Malea

1996
Effect of thiamine deficiency on levels of putative amino acid transmitters in affected regions of the rat brain.
    Journal of neurochemistry, 1979, Volume: 33, Issue:2

    Topics: Animals; Aspartic Acid; Brain Chemistry; Cerebellum; gamma-Aminobutyric Acid; Glutamine; Glycine; Ma

1979
Amino acid changes in thiamine-deficient encephalopathy: some implications for the pathogenesis of Friedreich's ataxia.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1979, Volume: 6, Issue:2

    Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Diseases; Friedreich Ataxia; gamma-Aminobutyric Ac

1979
Combined metabolic effects of ethanol and thiamine deficiency in the central nervous system.
    Biochemical pharmacology, 1978, Volume: 27, Issue:8

    Topics: Adenosine Triphosphate; Animals; Brain; Ethanol; gamma-Aminobutyric Acid; Gluconates; Glucose; Gluco

1978
Brain glutamate and gamma-aminobutyrate (GABA) metabolism in thiamin-deficient rats.
    The British journal of nutrition, 1989, Volume: 62, Issue:2

    Topics: Animals; Brain; gamma-Aminobutyric Acid; Glutamates; Male; Rats; Rats, Inbred Strains; Thiamine Defi

1989
Enhanced sensitivity of cerebellar Purkinje cells to iontophoretically-applied serotonin in thiamine deficiency.
    Brain research, 1985, Feb-18, Volume: 327, Issue:1-2

    Topics: Animals; Differential Threshold; Dose-Response Relationship, Drug; Electrophysiology; gamma-Aminobut

1985