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gamma-aminobutyric acid and Deficiency, Pyridoxine

gamma-aminobutyric acid has been researched along with Deficiency, Pyridoxine in 29 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Research Excerpts

ExcerptRelevanceReference
"An 8-year-old girl treated at our facility for superrefractory status epilepticus was found to have a low pyridoxine level at 5 μg/L."7.81Pyridoxine deficiency in adult patients with status epilepticus. ( Dave, HN; Eugene Ramsay, R; Irland, M; Khan, F; Sabharwal, V, 2015)
" Adult male Sprague-Dawley rats placed on a pyridoxine-deficient diet for 8 weeks showed significant hypertension compared with pyridoxine-supplemented controls."7.67Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat. ( Dakshinamurti, K; Packer, S; Paulose, CS; Stephens, NL, 1988)
"Pyridoxine-dependent seizures occur as a result of an increased requirement of the vitamin within the central nervous system."7.66Pyridoxine-dependent seizures. ( Crowell, GF; Roach, ES, 1983)
"A selective pyridoxine deficiency was seen in 94% of patients with status epilepticus (compared to 39."5.42Pyridoxine deficiency in adult patients with status epilepticus. ( Dave, HN; Eugene Ramsay, R; Irland, M; Khan, F; Sabharwal, V, 2015)
"Pyridoxine-dependent seizures occur as a result of an increased requirement of the vitamin within the central nervous system."5.27Pyridoxine-dependent seizures. ( Crowell, GF; Roach, ES, 1983)
"Treatment of pyridoxine-deficient rats with a single dose of pyridoxine (10 mg/kg body weight) reversed the blood pressure to normal levels within 24 hours, with concomitant restorations of hypothalamic serotonin and gamma-aminobutyric acid as well as the return of plasma norepinephrine and epinephrine to normal levels."5.27Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat. ( Dakshinamurti, K; Packer, S; Paulose, CS; Stephens, NL, 1988)
"Hypertension was associated with sympathetic stimulation."5.27Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat. ( Dakshinamurti, K; Packer, S; Paulose, CS; Stephens, NL, 1988)
"An 8-year-old girl treated at our facility for superrefractory status epilepticus was found to have a low pyridoxine level at 5 μg/L."3.81Pyridoxine deficiency in adult patients with status epilepticus. ( Dave, HN; Eugene Ramsay, R; Irland, M; Khan, F; Sabharwal, V, 2015)
" Adult male Sprague-Dawley rats placed on a pyridoxine-deficient diet for 8 weeks showed significant hypertension compared with pyridoxine-supplemented controls."3.67Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat. ( Dakshinamurti, K; Packer, S; Paulose, CS; Stephens, NL, 1988)
"Pyridoxine-dependent seizures occur as a result of an increased requirement of the vitamin within the central nervous system."3.66Pyridoxine-dependent seizures. ( Crowell, GF; Roach, ES, 1983)
"A selective pyridoxine deficiency was seen in 94% of patients with status epilepticus (compared to 39."1.42Pyridoxine deficiency in adult patients with status epilepticus. ( Dave, HN; Eugene Ramsay, R; Irland, M; Khan, F; Sabharwal, V, 2015)
"They also exhibited severe seizure discharge activity of prolonged duration at any given dose of either picrotoxin or pentylene tetrazole."1.29Picrotoxin and pentylene tetrazole induced seizure activity in pyridoxine-deficient rats. ( Bolster, B; Dakshinamurti, K; Sharma, SK, 1994)
"Pyridoxine-dependent seizures occur as a result of an increased requirement of the vitamin within the central nervous system."1.27Pyridoxine-dependent seizures. ( Crowell, GF; Roach, ES, 1983)
"Treatment of pyridoxine-deficient rats with a single dose of pyridoxine (10 mg/kg body weight) reversed the blood pressure to normal levels within 24 hours, with concomitant restorations of hypothalamic serotonin and gamma-aminobutyric acid as well as the return of plasma norepinephrine and epinephrine to normal levels."1.27Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat. ( Dakshinamurti, K; Packer, S; Paulose, CS; Stephens, NL, 1988)
"Hypertension was associated with sympathetic stimulation."1.27Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat. ( Dakshinamurti, K; Packer, S; Paulose, CS; Stephens, NL, 1988)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199014 (48.28)18.7374
1990's8 (27.59)18.2507
2000's2 (6.90)29.6817
2010's5 (17.24)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kumrungsee, T1
Nirmagustina, DE1
Arima, T1
Onishi, K1
Sato, K1
Kato, N1
Yanaka, N1
Mayengbam, S1
House, JD1
Aliani, M1
Kobayashi, D1
Yoshimura, T1
Johno, A1
Ishikawa, M1
Sasaki, K1
Wada, K1
Dave, HN1
Eugene Ramsay, R1
Khan, F1
Sabharwal, V1
Irland, M1
Almeida, MR1
Mabasa, L1
Crane, C1
Park, CS1
Venâncio, VP1
Bianchi, ML1
Antunes, LM1
Alkan, A1
Kutlu, R1
Aslan, M1
Sigirci, A1
Orkan, I1
Yakinci, C1
Paulose, CS3
Dakshinamurti, K6
Bonkowsky, HL1
Schady, W1
Crowell, GF1
Roach, ES1
Wasynczuk, A1
Kirksey, A1
Morré, DM1
Waymire, KG1
Mahuren, JD1
Jaje, JM1
Guilarte, TR5
Coburn, SP1
MacGregor, GR1
Sharma, SK1
Bolster, B1
Pilachowski, J1
Gerster, H1
Tanase, S1
McCarty, MF1
Martin, SB1
Martin, DL1
Ota, K1
Ackroyd, B1
Smith, WR1
Kurlemann, G1
Menges, EM1
Palm, DG1
Korinthenberg, R1
Schultze, C1
Block, LD1
Wagner, HN1
Packer, S1
Stephens, NL1
Wiechert, P1

Reviews

5 reviews available for gamma-aminobutyric acid and Deficiency, Pyridoxine

ArticleYear
Neurobiology of Pyridoxine.
    Advances in nutritional research, 1982, Volume: 4

    Topics: Animals; Brain; Carboxy-Lyases; Cats; Crustacea; gamma-Aminobutyric Acid; Glutamate Decarboxylase; H

1982
Neurologic manifestations of acute porphyria.
    Seminars in liver disease, 1982, Volume: 2, Issue:2

    Topics: Acute Disease; Aminolevulinic Acid; Animals; Central Nervous System; Depression; Electrophysiology;

1982
[The importance of vitamin B 6 for development of the infant. Human medical and animal experiment studies].
    Zeitschrift fur Ernahrungswissenschaft, 1996, Volume: 35, Issue:4

    Topics: Animals; Central Nervous System; Central Nervous System Diseases; Dopamine; Female; gamma-Aminobutyr

1996
[Vitamin B6 dependency syndrome (vitamin B6 dependent seizures, convulsions)].
    Ryoikibetsu shokogun shirizu, 1998, Issue:19 Pt 2

    Topics: Biomarkers; Electroencephalography; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Prognosis; Pyr

1998
[Vitamin dependency].
    Horumon to rinsho. Clinical endocrinology, 1975, Volume: 23, Issue:9

    Topics: Anemia, Sideroblastic; Animals; Biotin; Crotonates; Cystathionine; gamma-Aminobutyric Acid; Glutamat

1975

Other Studies

24 other studies available for gamma-aminobutyric acid and Deficiency, Pyridoxine

ArticleYear
Novel metabolic disturbances in marginal vitamin B
    The Journal of nutritional biochemistry, 2019, Volume: 65

    Topics: Animals; Body Weight; Carboxy-Lyases; Eating; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hear

2019
Investigation of vitamin B₆ inadequacy, induced by exposure to the anti-B₆ factor 1-amino D-proline, on plasma lipophilic metabolites of rats: a metabolomics approach.
    European journal of nutrition, 2016, Volume: 55, Issue:3

    Topics: Animals; Biomarkers; Cystamine; Flax; gamma-Aminobutyric Acid; Glycocholic Acid; Indoles; Male; Meta

2016
Decrease in pyridoxal-5'-phosphate concentration and increase in pyridoxal concentration in rat plasma by 4'-O-methylpyridoxine administration.
    Nutrition research (New York, N.Y.), 2015, Volume: 35, Issue:7

    Topics: Animals; Brain; Disease Models, Animal; Foodborne Diseases; gamma-Aminobutyric Acid; Ginkgo biloba;

2015
Pyridoxine deficiency in adult patients with status epilepticus.
    Epilepsy & behavior : E&B, 2015, Volume: 52, Issue:Pt A

    Topics: Adult; Child; Electroencephalography; Female; gamma-Aminobutyric Acid; Humans; Pyridoxine; Seizures;

2015
Maternal vitamin B6 deficient or supplemented diets on expression of genes related to GABAergic, serotonergic, or glutamatergic pathways in hippocampus of rat dams and their offspring.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:7

    Topics: Animals; Animals, Newborn; Dietary Supplements; DNA Methylation; Female; Fibroblast Growth Factor 2;

2016
Pyridoxine-dependent seizures: magnetic resonance spectroscopy findings.
    Journal of child neurology, 2004, Volume: 19, Issue:1

    Topics: Aspartic Acid; Brain Damage, Chronic; Child; Choline; Consanguinity; Creatine; Diagnosis, Differenti

2004
Enhancement of high affinity gamma-aminobutyric acid receptor binding in cerebellum of pyridoxine-deficient rat.
    Neuroscience letters, 1984, Aug-10, Volume: 48, Issue:3

    Topics: Animals; Baclofen; Cerebellum; gamma-Aminobutyric Acid; Kinetics; Rats; Rats, Inbred Strains; Recept

1984
Consequences of brain monoamine changes in the pyridoxine-deficient young rat.
    Progress in clinical and biological research, 1984, Volume: 144A

    Topics: Animals; Brain; Dopamine; gamma-Aminobutyric Acid; Kinetics; Male; Pyridoxal Phosphate; Rats; Rats,

1984
Pyridoxine-dependent seizures.
    American family physician, 1983, Volume: 27, Issue:3

    Topics: Electroencephalography; gamma-Aminobutyric Acid; Humans; Infant; Infant, Newborn; Infant, Newborn, D

1983
Effects of maternal vitamin B-6 deficiency on specific regions of developing rat brain: the extrapyramidal motor system.
    The Journal of nutrition, 1983, Volume: 113, Issue:4

    Topics: Amino Acids; Animals; Basal Ganglia; Brain; Cell Count; Cerebral Cortex; Dopamine; Female; gamma-Ami

1983
Mice lacking tissue non-specific alkaline phosphatase die from seizures due to defective metabolism of vitamin B-6.
    Nature genetics, 1995, Volume: 11, Issue:1

    Topics: Alkaline Phosphatase; Animals; Brain Chemistry; Calcification, Physiologic; Disease Models, Animal;

1995
Picrotoxin and pentylene tetrazole induced seizure activity in pyridoxine-deficient rats.
    Journal of the neurological sciences, 1994, Volume: 121, Issue:1

    Topics: Animals; Cerebral Cortex; Differential Threshold; Electroencephalography; Electronic Data Processing

1994
Postnatal development and GABA allosteric modulation of benzodiazepine receptor binding in the vitamin B-6 deficient rat brain.
    Neurochemical research, 1993, Volume: 18, Issue:12

    Topics: Aging; Allosteric Regulation; Animals; Brain; Cell Membrane; Cerebellum; Cerebral Cortex; Female; Fl

1993
High-dose pyridoxine as an 'anti-stress' strategy.
    Medical hypotheses, 2000, Volume: 54, Issue:5

    Topics: Animals; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Humans; Pyridoxine; Serotonin; S

2000
Brain neurotransmitters in pyridoxine deficiency [proceedings].
    Biochemical Society transactions, 1978, Volume: 6, Issue:1

    Topics: Animals; Biogenic Amines; Brain; gamma-Aminobutyric Acid; Neurotransmitter Agents; Rats; Vitamin B 6

1978
Stimulation by phosphate on the activation of glutamate apodecarboxylase by pyridoxyl-5'-phosphate and its implications for the control of GABA synthesis.
    Journal of neurochemistry, 1979, Volume: 33, Issue:6

    Topics: Animals; Apoenzymes; Apoproteins; Brain; Carboxy-Lyases; Enzyme Activation; gamma-Aminobutyric Acid;

1979
Further studies on brain gamma-aminobutyric acid metabolism after administration of pyridoxine to vitamin B-6-deficient suckling rats.
    Biochemical Society transactions, 1975, Volume: 3, Issue:5

    Topics: Aminobutyrates; Animals; Aspartate Aminotransferases; Brain; Female; gamma-Aminobutyric Acid; Glutam

1975
Abnormal endogenous amino acid release in brain slices from vitamin B-6 restricted neonatal rats.
    Neuroscience letters, 1991, Jan-02, Volume: 121, Issue:1-2

    Topics: Amino Acids; Animals; Animals, Newborn; Brain Chemistry; Chromatography, High Pressure Liquid; Elect

1991
Low level of GABA in CSF in vitamin B6-dependent seizures.
    Developmental medicine and child neurology, 1991, Volume: 33, Issue:8

    Topics: Electroencephalography; gamma-Aminobutyric Acid; Humans; Infant; Male; Pyridoxine; Spasms, Infantile

1991
[Pyridoxine-dependent seizures. Remarks on clinical variability and pathogenesis].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1990, Volume: 138, Issue:11

    Topics: Anticonvulsants; Electroencephalography; Follow-Up Studies; gamma-Aminobutyric Acid; Humans; Infant;

1990
Regional changes in the concentrations of glutamate, glycine, taurine, and GABA in the vitamin B-6 deficient developing rat brain: association with neonatal seizures.
    Neurochemical research, 1989, Volume: 14, Issue:9

    Topics: Amino Acids; Animals; Animals, Newborn; Brain; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic

1989
The putative endogenous convulsant 3-hydroxykynurenine decreases benzodiazepine receptor binding affinity: implications to seizures associated with neonatal vitamin B-6 deficiency.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 30, Issue:3

    Topics: Animals; Brain; Convulsants; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Kynurenine; Male; Rat

1988
Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat.
    Hypertension (Dallas, Tex. : 1979), 1988, Volume: 11, Issue:4

    Topics: Animals; Blood Pressure; Dopamine; gamma-Aminobutyric Acid; Hypertension; Hypothalamus; Male; Norepi

1988
[Significance of pyridoxine and gamma-aminobutyric acid in cerebral seizures].
    Zeitschrift fur arztliche Fortbildung, 1971, Apr-15, Volume: 65, Issue:8

    Topics: Animals; Epilepsy; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Pyridoxine; Vitamin B 6 Deficie

1971