gamma-aminobutyric acid has been researched along with Constipation in 8 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Constipation: Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess effects of pregabalin on colonic compliance, sensory and motor functions in patients with constipation-predominant irritable bowel syndrome." | 9.19 | Pilot trial: pregabalin on colonic sensorimotor functions in irritable bowel syndrome. ( Burton, D; Busciglio, I; Camilleri, M; Iturrino, J; Zinsmeister, AR, 2014) |
| "In a pilot, double-blind, placebo-controlled, parallel-group study, we tested oral pregabalin, 200mg, in 18 patients with constipation-predominant irritable bowel syndrome." | 9.19 | Pilot trial: pregabalin on colonic sensorimotor functions in irritable bowel syndrome. ( Burton, D; Busciglio, I; Camilleri, M; Iturrino, J; Zinsmeister, AR, 2014) |
| "Pregabalin, 200mg, might not reduce distension-related colonic pain in constipation-predominant irritable bowel syndrome patients." | 9.19 | Pilot trial: pregabalin on colonic sensorimotor functions in irritable bowel syndrome. ( Burton, D; Busciglio, I; Camilleri, M; Iturrino, J; Zinsmeister, AR, 2014) |
| "In prior studies, pregabalin reduced rectal or colonic pain in patients with irritable bowel syndrome and healthy adults, suggesting reduction of afferent function." | 9.19 | Pilot trial: pregabalin on colonic sensorimotor functions in irritable bowel syndrome. ( Burton, D; Busciglio, I; Camilleri, M; Iturrino, J; Zinsmeister, AR, 2014) |
| "The incidence of constipation as an adverse effect of pregabalin has previously been reported as low, with all cases described as either mild or moderate." | 7.76 | Severe and disabling constipation: an adverse effect of pregabalin. ( Cook, MJ; D'Souza, WJ; Kamel, JT, 2010) |
| "The incidence of constipation as an adverse effect of pregabalin has previously been reported as low, with all cases described as either mild or moderate." | 5.36 | Severe and disabling constipation: an adverse effect of pregabalin. ( Cook, MJ; D'Souza, WJ; Kamel, JT, 2010) |
| "Constipation was the most frequent adverse effect that required pregabalin to be withdrawn (6." | 5.36 | Severe and disabling constipation: an adverse effect of pregabalin. ( Cook, MJ; D'Souza, WJ; Kamel, JT, 2010) |
| "To assess effects of pregabalin on colonic compliance, sensory and motor functions in patients with constipation-predominant irritable bowel syndrome." | 5.19 | Pilot trial: pregabalin on colonic sensorimotor functions in irritable bowel syndrome. ( Burton, D; Busciglio, I; Camilleri, M; Iturrino, J; Zinsmeister, AR, 2014) |
| "In a pilot, double-blind, placebo-controlled, parallel-group study, we tested oral pregabalin, 200mg, in 18 patients with constipation-predominant irritable bowel syndrome." | 5.19 | Pilot trial: pregabalin on colonic sensorimotor functions in irritable bowel syndrome. ( Burton, D; Busciglio, I; Camilleri, M; Iturrino, J; Zinsmeister, AR, 2014) |
| "Pregabalin, 200mg, might not reduce distension-related colonic pain in constipation-predominant irritable bowel syndrome patients." | 5.19 | Pilot trial: pregabalin on colonic sensorimotor functions in irritable bowel syndrome. ( Burton, D; Busciglio, I; Camilleri, M; Iturrino, J; Zinsmeister, AR, 2014) |
| "In prior studies, pregabalin reduced rectal or colonic pain in patients with irritable bowel syndrome and healthy adults, suggesting reduction of afferent function." | 5.19 | Pilot trial: pregabalin on colonic sensorimotor functions in irritable bowel syndrome. ( Burton, D; Busciglio, I; Camilleri, M; Iturrino, J; Zinsmeister, AR, 2014) |
| "The incidence of constipation as an adverse effect of pregabalin has previously been reported as low, with all cases described as either mild or moderate." | 3.76 | Severe and disabling constipation: an adverse effect of pregabalin. ( Cook, MJ; D'Souza, WJ; Kamel, JT, 2010) |
| "Pain was rated on a scale from 0 (no pain) to 10 (maximum pain)." | 2.52 | Pharmacological treatment for pain in Guillain-Barré syndrome. ( Liu, J; McNicol, ED; Wang, LN, 2015) |
| "Pain was rated on a scale from 0 (no pain) to 10 (maximum pain)." | 2.49 | Pharmacological treatment for pain in Guillain-Barré syndrome. ( Liu, J; McNicol, ED; Wang, LN, 2013) |
| "The incidence of constipation as an adverse effect of pregabalin has previously been reported as low, with all cases described as either mild or moderate." | 1.36 | Severe and disabling constipation: an adverse effect of pregabalin. ( Cook, MJ; D'Souza, WJ; Kamel, JT, 2010) |
| "Constipation was the most frequent adverse effect that required pregabalin to be withdrawn (6." | 1.36 | Severe and disabling constipation: an adverse effect of pregabalin. ( Cook, MJ; D'Souza, WJ; Kamel, JT, 2010) |
| " To examine the potential for drug-drug interactions at these two transporters, the pharmacokinetics of gabapentin enacarbil were evaluated in healthy adults after administration alone or in combination with either naproxen (an MCT-1 substrate) or cimetidine (an OCT2 substrate)." | 1.36 | Clinical pharmacokinetic drug interaction studies of gabapentin enacarbil, a novel transported prodrug of gabapentin, with naproxen and cimetidine. ( Blumenthal, R; Cundy, KC; Ho, J; Lal, R; Luo, W; Sukbuntherng, J; Vicente, V, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (87.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iturrino, J | 1 |
| Camilleri, M | 1 |
| Busciglio, I | 1 |
| Burton, D | 1 |
| Zinsmeister, AR | 1 |
| Liu, J | 2 |
| Wang, LN | 2 |
| McNicol, ED | 2 |
| Takii, Y | 1 |
| Nishimura, S | 1 |
| Yoshida-Yamamoto, S | 1 |
| Kobayashi, Y | 1 |
| Nagayoshi, E | 1 |
| Kamel, JT | 1 |
| D'Souza, WJ | 1 |
| Cook, MJ | 1 |
| Lal, R | 1 |
| Sukbuntherng, J | 1 |
| Luo, W | 1 |
| Vicente, V | 1 |
| Blumenthal, R | 1 |
| Ho, J | 1 |
| Cundy, KC | 1 |
| Sarkissian, A | 1 |
| Neher, JO | 1 |
| Singh, R | 1 |
| St Anna, L | 1 |
| Reiner, DJ | 1 |
| Thomas, JH | 1 |
3 reviews available for gamma-aminobutyric acid and Constipation
| Article | Year |
|---|---|
Pharmacological treatment for pain in Guillain-Barré syndrome.
Topics: Amines; Analgesics; Carbamazepine; Constipation; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Amin | 2013 |
Pharmacological treatment for pain in Guillain-Barré syndrome.
Topics: Amines; Analgesics; Carbamazepine; Constipation; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Amin | 2015 |
Clinical Inquiry: Do venlafaxine and gabapentin control hot flashes in women with a history of breast cancer?
Topics: Amines; Anti-Anxiety Agents; Breast Neoplasms; Constipation; Cyclohexanecarboxylic Acids; Cyclohexan | 2012 |
2 trials available for gamma-aminobutyric acid and Constipation
| Article | Year |
|---|---|
Pilot trial: pregabalin on colonic sensorimotor functions in irritable bowel syndrome.
Topics: Adult; Analgesics; Colon; Compliance; Constipation; Double-Blind Method; Female; gamma-Aminobutyric | 2014 |
Effects of intake of pickles containing Lactobacillus brevis on immune activity and bowel symptoms in female students.
Topics: Adult; Constipation; Diet; Feces; Female; Food, Preserved; Functional Food; gamma-Aminobutyric Acid; | 2013 |
3 other studies available for gamma-aminobutyric acid and Constipation
| Article | Year |
|---|---|
Severe and disabling constipation: an adverse effect of pregabalin.
Topics: Adult; Ambulatory Care; Constipation; Epilepsy; Female; Follow-Up Studies; gamma-Aminobutyric Acid; | 2010 |
Clinical pharmacokinetic drug interaction studies of gabapentin enacarbil, a novel transported prodrug of gabapentin, with naproxen and cimetidine.
Topics: Adolescent; Adult; Biological Transport; Carbamates; Cimetidine; Constipation; Dose-Response Relatio | 2010 |
Reversal of a muscle response to GABA during C. elegans male development.
Topics: Aging; Anal Canal; Animals; Caenorhabditis elegans; Constipation; Defecation; gamma-Aminobutyric Aci | 1995 |