gamma-aminobutyric acid has been researched along with Complications, Pregnancy in 24 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vigabatrin was specifically designed to enhance gamma-aminobutyric acid (GABA) function in the CNS." | 7.77 | Vigabatrin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy and disorders of motor control. ( Grant, SM; Heel, RC, 1991) |
| "The objective of this study was to assess the safety of gabapentin (Neurontin) exposure in human pregnancy." | 7.72 | Gabapentin exposure in human pregnancy: results from the Gabapentin Pregnancy Registry. ( Montouris, G, 2003) |
| "In a previous paper, I have proposed that the deficiency of an endogenous caffeine-like substance is the underlying pathogenic mechanism in schizophrenia (1)." | 7.68 | Exploring the role of an endogenous caffeine-like substance in the pathogenesis of schizophrenia. ( Missak, SS, 1991) |
| " GBP plasma concentrations in the neonates declined with an estimated half-life of 14 h." | 5.33 | Pharmacokinetics of gabapentin during delivery, in the neonatal period, and lactation: does a fetal accumulation occur during pregnancy? ( Ohman, I; Tomson, T; Vitols, S, 2005) |
| "Vigabatrin was specifically designed to enhance gamma-aminobutyric acid (GABA) function in the CNS." | 3.77 | Vigabatrin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy and disorders of motor control. ( Grant, SM; Heel, RC, 1991) |
| " By contrast, offspring of rats exposed to carbamazepine (which at the dose used produced low plasma concentrations) or to generalized convulsive seizures showed no clear-cut evidence of dysplasias." | 3.74 | Fetal exposure to GABA-acting antiepileptic drugs generates hippocampal and cortical dysplasias. ( Ben-Ari, Y; Depaulis, A; Jorquera, I; Manent, JB; Mazzucchelli, I; Perucca, E; Represa, A, 2007) |
| "The objective of this study was to assess the safety of gabapentin (Neurontin) exposure in human pregnancy." | 3.72 | Gabapentin exposure in human pregnancy: results from the Gabapentin Pregnancy Registry. ( Montouris, G, 2003) |
| " In the last decade, pregnancy registries have been activated by collaborative groups of physicians in Europe (EURAP), North America (NAREP), Australia and India (the latter two recently merged into EURAP), to enroll a large number of exposed women to be monitored prospectively with standardized methods, and by three pharmaceutical companies marketing lamotrigine, gabapentin and vigabatrin, as part of their post-marketing surveillance." | 3.71 | Pregnancy registries in epilepsy. ( Annegers, JF; Beghi, E, 2001) |
| "5 months of pregnancy then carbamazepine 400 mg LP x 2/day, raised to 600 mg LP x 2/day at the 25th week of gestation because of epileptic crisis." | 3.69 | [Carbamazepine and vigabatrin in epileptic pregnant woman and side effects in the newborn infant]. ( Aboulghit, H; Beust, M; Kayemba Kay'S, S; Mourtada, A; Voisin, M, 1997) |
| "Newborns of epileptic mothers treated with carbamazepine and/or vigabatrin during pregnancy should be placed under clinical observation during their first postnatal week." | 3.69 | [Carbamazepine and vigabatrin in epileptic pregnant woman and side effects in the newborn infant]. ( Aboulghit, H; Beust, M; Kayemba Kay'S, S; Mourtada, A; Voisin, M, 1997) |
| "In a previous paper, I have proposed that the deficiency of an endogenous caffeine-like substance is the underlying pathogenic mechanism in schizophrenia (1)." | 3.68 | Exploring the role of an endogenous caffeine-like substance in the pathogenesis of schizophrenia. ( Missak, SS, 1991) |
| "Idiopathic restless legs syndrome (RLS) can severely affect quality of life and disturb sleep, so that pharmacological treatment is necessary, especially for elderly patients." | 2.52 | Restless legs syndrome-current therapies and management of augmentation. ( Inoue, Y; Paulus, W; Trenkwalder, C; Winkelmann, J, 2015) |
| " The most commonly used dosage was 450 mg/d." | 1.36 | [Lyrica (pregabalin) in the treatment of focal refractory epilepsy in adults]. ( Andreeva, OV; Iakunina, AV; Kalinin, VA; Vlasov, PN, 2010) |
| "While seizures may affect adversely maternal and fetal outcome, antiepileptic drugs (AEDs) may increase the incidence of congenital abnormalities and possibly affect postnatal cognitive development in the offspring." | 1.34 | Fetal exposure to GABA-acting antiepileptic drugs generates hippocampal and cortical dysplasias. ( Ben-Ari, Y; Depaulis, A; Jorquera, I; Manent, JB; Mazzucchelli, I; Perucca, E; Represa, A, 2007) |
| " GBP plasma concentrations in the neonates declined with an estimated half-life of 14 h." | 1.33 | Pharmacokinetics of gabapentin during delivery, in the neonatal period, and lactation: does a fetal accumulation occur during pregnancy? ( Ohman, I; Tomson, T; Vitols, S, 2005) |
| "Vigabatrin is a new antiepileptic medication consisting of a racemic mixture of 50% active S enantiomer and 50% inactive R enantiomer." | 1.30 | Vigabatrin: placental transfer in vivo and excretion into breast milk of the enantiomers. ( Mai, J; Mumford, JP; O'Mahoney, T; Olive, G; Rey, E; Tran, A, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.17) | 18.7374 |
| 1990's | 4 (16.67) | 18.2507 |
| 2000's | 9 (37.50) | 29.6817 |
| 2010's | 9 (37.50) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Skorput, AG | 1 |
| Lee, SM | 1 |
| Yeh, PW | 1 |
| Yeh, HH | 1 |
| Marguet, F | 1 |
| Friocourt, G | 1 |
| Brosolo, M | 1 |
| Sauvestre, F | 1 |
| Marcorelles, P | 1 |
| Lesueur, C | 1 |
| Marret, S | 1 |
| Gonzalez, BJ | 1 |
| Laquerrière, A | 1 |
| Konen, C | 1 |
| Niederst, E | 1 |
| Milstein, R | 1 |
| Amital, D | 1 |
| Arnson, Y | 1 |
| Amital, H | 1 |
| Nagandla, K | 1 |
| De, S | 1 |
| Lonstein, JS | 1 |
| Maguire, J | 1 |
| Meinlschmidt, G | 1 |
| Neumann, ID | 1 |
| Trenkwalder, C | 1 |
| Winkelmann, J | 1 |
| Inoue, Y | 2 |
| Paulus, W | 1 |
| Vanya, M | 1 |
| Devosa, I | 1 |
| Szok, D | 1 |
| Bártfai, G | 1 |
| Cerimagic, D | 1 |
| Bilic, E | 1 |
| Vlasov, PN | 1 |
| Andreeva, OV | 1 |
| Iakunina, AV | 1 |
| Kalinin, VA | 1 |
| Terada, K | 1 |
| Montouris, G | 1 |
| Wu, SP | 1 |
| Shyu, MK | 1 |
| Liou, HH | 1 |
| Gau, CS | 1 |
| Lin, CJ | 1 |
| Ohman, I | 1 |
| Vitols, S | 1 |
| Tomson, T | 1 |
| Amin, Z | 1 |
| Mason, GF | 1 |
| Cavus, I | 1 |
| Krystal, JH | 1 |
| Rothman, DL | 1 |
| Epperson, CN | 1 |
| Manent, JB | 1 |
| Jorquera, I | 1 |
| Mazzucchelli, I | 1 |
| Depaulis, A | 1 |
| Perucca, E | 1 |
| Ben-Ari, Y | 1 |
| Represa, A | 1 |
| Taéron, C | 1 |
| Wasynczuk, A | 1 |
| Kirksey, A | 1 |
| Morré, DM | 1 |
| Kayemba Kay'S, S | 1 |
| Beust, M | 1 |
| Aboulghit, H | 1 |
| Voisin, M | 1 |
| Mourtada, A | 1 |
| Tran, A | 1 |
| O'Mahoney, T | 1 |
| Rey, E | 1 |
| Mai, J | 1 |
| Mumford, JP | 1 |
| Olive, G | 1 |
| Chaudron, LH | 1 |
| Jefferson, JW | 1 |
| Beghi, E | 1 |
| Annegers, JF | 1 |
| Grant, SM | 1 |
| Heel, RC | 1 |
| Missak, SS | 1 |
7 reviews available for gamma-aminobutyric acid and Complications, Pregnancy
| Article | Year |
|---|---|
Restless legs syndrome: pathophysiology and modern management.
Topics: Amines; Anemia; Anticonvulsants; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Dopamine Agon | 2013 |
Emotion and mood adaptations in the peripartum female:complementary contributions of GABA and oxytocin.
Topics: Adaptation, Psychological; Affect; Animals; Anxiety; Depression; Emotions; Female; gamma-Aminobutyri | 2014 |
Restless legs syndrome-current therapies and management of augmentation.
Topics: Amines; Analgesics, Opioid; Anticonvulsants; Cyclohexanecarboxylic Acids; Dopamine Agonists; Drug Sy | 2015 |
[Preconceptional and perinatal challenges of pregnancy in women with epilepsy].
Topics: Adult; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epileps | 2016 |
The interaction of neuroactive steroids and GABA in the development of neuropsychiatric disorders in women.
Topics: Affect; Depression, Postpartum; Female; gamma-Aminobutyric Acid; Humans; Menstruation; Mental Disord | 2006 |
Mood stabilizers during breastfeeding: a review.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Breast Feeding; Carbamazepine; Cyclohexanecarbo | 2000 |
Vigabatrin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy and disorders of motor control.
Topics: 4-Aminobutyrate Transaminase; Adult; Aged; Aminocaproates; Animals; Ataxia; Child; Dyskinesia, Drug- | 1991 |
1 trial available for gamma-aminobutyric acid and Complications, Pregnancy
| Article | Year |
|---|---|
Vigabatrin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy and disorders of motor control.
Topics: 4-Aminobutyrate Transaminase; Adult; Aged; Aminocaproates; Animals; Ataxia; Child; Dyskinesia, Drug- | 1991 |
17 other studies available for gamma-aminobutyric acid and Complications, Pregnancy
| Article | Year |
|---|---|
The NKCC1 antagonist bumetanide mitigates interneuronopathy associated with ethanol exposure in utero.
Topics: Alcohol Drinking; Animals; Bumetanide; Cerebral Cortex; Disease Models, Animal; Female; Fetal Alcoho | 2019 |
Prenatal alcohol exposure is a leading cause of interneuronopathy in humans.
Topics: Alcohol Drinking; Alcoholism; Binge Drinking; Brain; Calbindin 2; Case-Control Studies; Cell Movemen | 2020 |
Special Issue on Disease: New Advances in Psychiatry.
Topics: Animals; Brain; Cerebellum; Depression, Postpartum; Depressive Disorder; Female; gamma-Aminobutyric | 2019 |
Retraumatization eliciting the presentation of fibromyalgia.
Topics: Adult; Analgesics; Antidepressive Agents; Cannabinoids; Duloxetine Hydrochloride; Female; Fibromyalg | 2013 |
Stiff-person syndrome first manifesting in pregnancy.
Topics: Adult; Autoantibodies; Autoimmune Diseases; Cesarean Section; Electromyography; Female; Follow-Up St | 2009 |
[Lyrica (pregabalin) in the treatment of focal refractory epilepsy in adults].
Topics: Adolescent; Adult; Anticonvulsants; Combined Modality Therapy; Epilepsies, Partial; Female; gamma-Am | 2010 |
[Clinical application of newer anti-epileptic drugs].
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma- | 2012 |
Gabapentin exposure in human pregnancy: results from the Gabapentin Pregnancy Registry.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; | 2003 |
Interaction between anticonvulsants and human placental carnitine transporter.
Topics: Acetates; Amines; Aminoisobutyric Acids; Anticonvulsants; Carnitine; Carrier Proteins; Culture Techn | 2004 |
Pharmacokinetics of gabapentin during delivery, in the neonatal period, and lactation: does a fetal accumulation occur during pregnancy?
Topics: Amines; Anticonvulsants; Breast Feeding; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fetal Blood; | 2005 |
Fetal exposure to GABA-acting antiepileptic drugs generates hippocampal and cortical dysplasias.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Female; Fetus | 2007 |
[Pregabalin].
Topics: Administration, Oral; Analgesics; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; | 2007 |
Effects of maternal vitamin B-6 deficiency on specific regions of developing rat brain: the extrapyramidal motor system.
Topics: Amino Acids; Animals; Basal Ganglia; Brain; Cell Count; Cerebral Cortex; Dopamine; Female; gamma-Ami | 1983 |
[Carbamazepine and vigabatrin in epileptic pregnant woman and side effects in the newborn infant].
Topics: Alkaline Phosphatase; Anticonvulsants; Carbamazepine; Chlorine; Drug Therapy, Combination; Epilepsy; | 1997 |
Vigabatrin: placental transfer in vivo and excretion into breast milk of the enantiomers.
Topics: Adult; Anticonvulsants; Central Nervous System; Female; Fetal Blood; gamma-Aminobutyric Acid; Humans | 1998 |
Pregnancy registries in epilepsy.
Topics: Abnormalities, Drug-Induced; Acetates; Amines; Anticonvulsants; Australia; Cross-Cultural Comparison | 2001 |
Exploring the role of an endogenous caffeine-like substance in the pathogenesis of schizophrenia.
Topics: Brain; Caffeine; Female; gamma-Aminobutyric Acid; Humans; Pregnancy; Pregnancy Complications; Recept | 1991 |