gamma-aminobutyric acid has been researched along with Complication, Postoperative in 37 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Excerpt | Relevance | Reference |
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"Although postoperative opioid use was reduced, perioperative administration of gabapentin did not result in a reduction of postoperative delirium or hospital length of stay." | 9.24 | Perioperative Gabapentin Does Not Reduce Postoperative Delirium in Older Surgical Patients: A Randomized Clinical Trial. ( Ames, C; Berven, S; Bozic, K; Burch, S; Chang, S; Chen, N; Chou, D; Covinsky, K; Deviren, V; Kinjo, S; Kramer, JH; Leung, JM; Meckler, G; Newman, S; Ries, M; Sands, LP; Tay, B; Tsai, T; Vail, T; Voss, V; Weinstein, P; Youngblom, E, 2017) |
"Adolescent patients undergoing idiopathic scoliosis surgery were randomized to receive a single preoperative dose of gabapentin 600 mg or placebo." | 9.19 | Analgesic effects of gabapentin after scoliosis surgery in children: a randomized controlled trial. ( Campbell, F; Mayell, A; Peliowski, A; Srinivasan, I, 2014) |
"A single preoperative dose of gabapentin did not show a significant difference in opioid consumption or pain scores in adolescents undergoing idiopathic scoliosis surgery." | 9.19 | Analgesic effects of gabapentin after scoliosis surgery in children: a randomized controlled trial. ( Campbell, F; Mayell, A; Peliowski, A; Srinivasan, I, 2014) |
" Pre-operative anxiety was significantly lower in the pregabalin group (2." | 9.15 | Effect of a single dose of pregabalin on post-operative pain and pre-operative anxiety in patients undergoing discectomy. ( Dahl, V; Raeder, J; Spreng, UJ, 2011) |
" The secondary outcomes were morphine consumption, pre-operative anxiety (VAS) and the occurrence of side effects." | 9.15 | Effect of a single dose of pregabalin on post-operative pain and pre-operative anxiety in patients undergoing discectomy. ( Dahl, V; Raeder, J; Spreng, UJ, 2011) |
"The VAS scores indicated that patients in the pregabalin group had significantly less shoulder pain on postoperative day (POD) 2 than those in the control group (control: 27." | 7.81 | Evaluation of postoperative pregabalin for attenuation of postoperative shoulder pain after thoracotomy in patients with lung cancer, a preliminary result. ( Goyagi, T; Horiguchi, T; Imai, K; Imai, Y; Kimura, T; Minamiya, Y; Motoyama, S; Nishikawa, T; Saito, H; Sato, Y, 2015) |
"Postoperative administration of pregabalin provided significant relief of postoperative shoulder pain during earlier POD after thoracic surgery for lung cancer when received multimodal analgesia in combination with NSAIDs." | 7.81 | Evaluation of postoperative pregabalin for attenuation of postoperative shoulder pain after thoracotomy in patients with lung cancer, a preliminary result. ( Goyagi, T; Horiguchi, T; Imai, K; Imai, Y; Kimura, T; Minamiya, Y; Motoyama, S; Nishikawa, T; Saito, H; Sato, Y, 2015) |
"Gabapentin was shown to be opioid sparing, with lower doses for the intervention group versus the control group." | 6.84 | Perioperative Gabapentin Does Not Reduce Postoperative Delirium in Older Surgical Patients: A Randomized Clinical Trial. ( Ames, C; Berven, S; Bozic, K; Burch, S; Chang, S; Chen, N; Chou, D; Covinsky, K; Deviren, V; Kinjo, S; Kramer, JH; Leung, JM; Meckler, G; Newman, S; Ries, M; Sands, LP; Tay, B; Tsai, T; Vail, T; Voss, V; Weinstein, P; Youngblom, E, 2017) |
"Gabapentin has antihyperalgesic and potential anxiolytic effects." | 6.77 | Effects of a single 1200-mg preoperative dose of gabapentin on anxiety and memory. ( Adam, F; Bordenave, L; Chauvin, M; Sessler, DI, 2012) |
"Delirium is a common complication in postoperative, critically ill patients." | 5.40 | The association of plasma gamma-aminobutyric acid concentration with postoperative delirium in critically ill patients. ( Egi, M; Kanazawa, T; Morita, K; Toda, Y; Yoshitaka, S, 2014) |
"Epidural fibrosis is among the most common causes of FBSS, and it is often recalcitrant to treatment." | 5.31 | Using gabapentin to treat failed back surgery syndrome caused by epidural fibrosis: A report of 2 cases. ( Braverman, DL; Lenrow, DA; Slipman, CW, 2001) |
"Gabapentin has an established, favorable safety profile and has been shown to be effective in various animal models and human studies of chronic neuropathic pain." | 5.31 | Using gabapentin to treat failed back surgery syndrome caused by epidural fibrosis: A report of 2 cases. ( Braverman, DL; Lenrow, DA; Slipman, CW, 2001) |
"A variety of treatments for the pain were ineffective." | 5.30 | Gabapentin for treatment of neuropathic pain in a 12-year-old girl. ( McGraw, T; Stacey, BR, 1998) |
"Although postoperative opioid use was reduced, perioperative administration of gabapentin did not result in a reduction of postoperative delirium or hospital length of stay." | 5.24 | Perioperative Gabapentin Does Not Reduce Postoperative Delirium in Older Surgical Patients: A Randomized Clinical Trial. ( Ames, C; Berven, S; Bozic, K; Burch, S; Chang, S; Chen, N; Chou, D; Covinsky, K; Deviren, V; Kinjo, S; Kramer, JH; Leung, JM; Meckler, G; Newman, S; Ries, M; Sands, LP; Tay, B; Tsai, T; Vail, T; Voss, V; Weinstein, P; Youngblom, E, 2017) |
"Adolescent patients undergoing idiopathic scoliosis surgery were randomized to receive a single preoperative dose of gabapentin 600 mg or placebo." | 5.19 | Analgesic effects of gabapentin after scoliosis surgery in children: a randomized controlled trial. ( Campbell, F; Mayell, A; Peliowski, A; Srinivasan, I, 2014) |
"A single preoperative dose of gabapentin did not show a significant difference in opioid consumption or pain scores in adolescents undergoing idiopathic scoliosis surgery." | 5.19 | Analgesic effects of gabapentin after scoliosis surgery in children: a randomized controlled trial. ( Campbell, F; Mayell, A; Peliowski, A; Srinivasan, I, 2014) |
" Pre-operative anxiety was significantly lower in the pregabalin group (2." | 5.15 | Effect of a single dose of pregabalin on post-operative pain and pre-operative anxiety in patients undergoing discectomy. ( Dahl, V; Raeder, J; Spreng, UJ, 2011) |
" The secondary outcomes were morphine consumption, pre-operative anxiety (VAS) and the occurrence of side effects." | 5.15 | Effect of a single dose of pregabalin on post-operative pain and pre-operative anxiety in patients undergoing discectomy. ( Dahl, V; Raeder, J; Spreng, UJ, 2011) |
"The VAS scores indicated that patients in the pregabalin group had significantly less shoulder pain on postoperative day (POD) 2 than those in the control group (control: 27." | 3.81 | Evaluation of postoperative pregabalin for attenuation of postoperative shoulder pain after thoracotomy in patients with lung cancer, a preliminary result. ( Goyagi, T; Horiguchi, T; Imai, K; Imai, Y; Kimura, T; Minamiya, Y; Motoyama, S; Nishikawa, T; Saito, H; Sato, Y, 2015) |
"Postoperative administration of pregabalin provided significant relief of postoperative shoulder pain during earlier POD after thoracic surgery for lung cancer when received multimodal analgesia in combination with NSAIDs." | 3.81 | Evaluation of postoperative pregabalin for attenuation of postoperative shoulder pain after thoracotomy in patients with lung cancer, a preliminary result. ( Goyagi, T; Horiguchi, T; Imai, K; Imai, Y; Kimura, T; Minamiya, Y; Motoyama, S; Nishikawa, T; Saito, H; Sato, Y, 2015) |
"Gabapentin is an antiepileptic medication that also has been used for restless legs syndrome." | 3.73 | Gabapentin-induced myopathy in 2 patients on short daily hemodialysis. ( Lavoie, S; Lipson, J; Zimmerman, D, 2005) |
"Gabapentin was shown to be opioid sparing, with lower doses for the intervention group versus the control group." | 2.84 | Perioperative Gabapentin Does Not Reduce Postoperative Delirium in Older Surgical Patients: A Randomized Clinical Trial. ( Ames, C; Berven, S; Bozic, K; Burch, S; Chang, S; Chen, N; Chou, D; Covinsky, K; Deviren, V; Kinjo, S; Kramer, JH; Leung, JM; Meckler, G; Newman, S; Ries, M; Sands, LP; Tay, B; Tsai, T; Vail, T; Voss, V; Weinstein, P; Youngblom, E, 2017) |
"Gabapentin has antihyperalgesic and potential anxiolytic effects." | 2.77 | Effects of a single 1200-mg preoperative dose of gabapentin on anxiety and memory. ( Adam, F; Bordenave, L; Chauvin, M; Sessler, DI, 2012) |
"Gabapentin is a gamma aminobutyric acid analogue that is known as an anticonvulsant drug." | 2.77 | Effect of gabapentin on postoperative pain and operation complications: a randomized placebo controlled trial. ( Abrishamkar, M; Ayatollahi, V; Bafghi, AT; Behdad, S; Tezerjani, MD, 2012) |
"Prevention and treatment of postoperative pain and operation complications such as nausea and vomiting are most important concerns in postoperative care." | 2.77 | Effect of gabapentin on postoperative pain and operation complications: a randomized placebo controlled trial. ( Abrishamkar, M; Ayatollahi, V; Bafghi, AT; Behdad, S; Tezerjani, MD, 2012) |
"Postoperative pain was assessed by a telephone interview 1 and 3 months after operation." | 2.76 | Pregabalin has an opioid-sparing effect in elderly patients after cardiac surgery: a randomized placebo-controlled trial. ( Hammarén, E; Kontinen, VK; Pesonen, A; Raivio, P; Rosenberg, PH; Suojaranta-Ylinen, R; Tarkkila, P, 2011) |
"Postoperative confusion was measured with the Confusion Assessment Method for the intensive care unit (CAM-ICU)." | 2.76 | Pregabalin has an opioid-sparing effect in elderly patients after cardiac surgery: a randomized placebo-controlled trial. ( Hammarén, E; Kontinen, VK; Pesonen, A; Raivio, P; Rosenberg, PH; Suojaranta-Ylinen, R; Tarkkila, P, 2011) |
"Infant delirium is an under-recognized clinical entity in neonatal intensive care, and earlier identification and treatment could minimize morbidities associated with this condition." | 1.46 | A case of infant delirium in the neonatal intensive care unit. ( Bidegain, M; Cotten, CM; Edwards, LE; Hornik, CD; Hutchison, LB; Smith, PB, 2017) |
"The incidence of respiratory depression was 153 (95% confidence interval [CI], 146-161) episodes per 1000 cases." | 1.46 | Multimodal Analgesic Therapy With Gabapentin and Its Association With Postoperative Respiratory Depression. ( Cavalcante, AN; Schroeder, DR; Sprung, J; Weingarten, TN, 2017) |
"Outcome measures were postsurgical pain at rest and during walking, consumption of opioids for pain rescue, knee swelling and knee range of motion, and complications." | 1.46 | Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty. ( Hansen, TB; Munk, S; Rytter, S; Stilling, M, 2017) |
"Delirium is a common complication in postoperative, critically ill patients." | 1.40 | The association of plasma gamma-aminobutyric acid concentration with postoperative delirium in critically ill patients. ( Egi, M; Kanazawa, T; Morita, K; Toda, Y; Yoshitaka, S, 2014) |
"Neuropathic and/or neuralgic facial pain occurred in 50% (n = 7)." | 1.35 | The trigeminal trophic syndrome: an unusual cause of face pain, dysaesthesias, anaesthesia and skin/soft tissue lesions. ( Garza, I, 2008) |
"Gabapentin appeared to be a safe, effective, and economical treatment for neuropathic pain in this horse." | 1.34 | Gabapentin for the treatment of neuropathic pain in a pregnant horse. ( Davis, JL; Elce, Y; Posner, LP, 2007) |
" Treatment was continued for 6 days, during which the dosage was progressively decreased, and the mare was discharged." | 1.34 | Gabapentin for the treatment of neuropathic pain in a pregnant horse. ( Davis, JL; Elce, Y; Posner, LP, 2007) |
"Following recovery from colic surgery to treat compression of the small and large intestines because of a large fetus, the mare was noticed to have signs of femoral neuropathy involving the left hind limb." | 1.34 | Gabapentin for the treatment of neuropathic pain in a pregnant horse. ( Davis, JL; Elce, Y; Posner, LP, 2007) |
"Gabapentin is an antiepileptic medication that also has been used for restless legs syndrome." | 1.33 | Gabapentin-induced myopathy in 2 patients on short daily hemodialysis. ( Lavoie, S; Lipson, J; Zimmerman, D, 2005) |
"The severe burning pain, deep pressure-like pain, and deep mechanical allodynia, which presented over the contralateral side to the TBI, were successfully relieved with motor cortex stimulation (MCS)." | 1.33 | Motor cortex stimulation for central pain following a traumatic brain injury. ( Choi, ES; Hong, JT; Lee, SW; Son, BC; Sung, JH, 2006) |
"Gabapentin has an established, favorable safety profile and has been shown to be effective in various animal models and human studies of chronic neuropathic pain." | 1.31 | Using gabapentin to treat failed back surgery syndrome caused by epidural fibrosis: A report of 2 cases. ( Braverman, DL; Lenrow, DA; Slipman, CW, 2001) |
"Epidural fibrosis is among the most common causes of FBSS, and it is often recalcitrant to treatment." | 1.31 | Using gabapentin to treat failed back surgery syndrome caused by epidural fibrosis: A report of 2 cases. ( Braverman, DL; Lenrow, DA; Slipman, CW, 2001) |
"A variety of treatments for the pain were ineffective." | 1.30 | Gabapentin for treatment of neuropathic pain in a 12-year-old girl. ( McGraw, T; Stacey, BR, 1998) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (5.41) | 18.7374 |
1990's | 2 (5.41) | 18.2507 |
2000's | 11 (29.73) | 29.6817 |
2010's | 21 (56.76) | 24.3611 |
2020's | 1 (2.70) | 2.80 |
Authors | Studies |
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Chan, JCY | 1 |
Waddell, TK | 1 |
Yasufuku, K | 1 |
Keshavjee, S | 1 |
Donahoe, LL | 1 |
Levenbrown, Y | 1 |
Hossain, MJ | 1 |
Keith, JP | 1 |
Burr, K | 1 |
Hesek, A | 1 |
Shaffer, TH | 1 |
Yao, LL | 1 |
Cao, JR | 1 |
Lyu, CJ | 1 |
Fan, FF | 1 |
Wang, HP | 1 |
Cao, HW | 1 |
Huang, J | 1 |
Mei, LH | 1 |
He, P | 1 |
Li, Y | 1 |
Zhang, R | 1 |
Ren, M | 1 |
Liu, H | 1 |
Yang, M | 1 |
Liu, X | 1 |
Wang, Z | 1 |
Xu, C | 1 |
Guan, J | 1 |
Wei, B | 1 |
Liu, Y | 1 |
Swinkels, BM | 1 |
Ten Berg, JM | 1 |
Kelder, JC | 1 |
Vermeulen, FE | 1 |
van Boven, WJ | 1 |
de Mol, BA | 1 |
Huang, K | 1 |
Yang, X | 1 |
Ma, Y | 1 |
Sun, G | 1 |
Nitin, N | 1 |
Wickramasinghe, A | 1 |
Xiao, Y | 1 |
Kobayashi, N | 1 |
Wang, S | 1 |
Scherpelz, KP | 1 |
Yamazaki, T | 1 |
Meredith, SC | 1 |
Ishii, Y | 1 |
Phoonsawat, K | 1 |
Khachornsakkul, K | 1 |
Ratnarathorn, N | 1 |
Henry, CS | 1 |
Dungchai, W | 1 |
Zareena, B | 1 |
Khadim, A | 1 |
Jeelani, SUY | 1 |
Hussain, S | 1 |
Ali, A | 1 |
Musharraf, SG | 1 |
Zhuo, X | 1 |
Jiang, W | 1 |
Qian, G | 1 |
Chen, J | 1 |
Yu, T | 1 |
Luo, L | 1 |
Lu, L | 1 |
Chen, Y | 1 |
Yin, S | 1 |
Hong, NJ | 1 |
Gonzalez-Vicente, A | 1 |
Saez, F | 1 |
Garvin, JL | 1 |
Hede, KTC | 1 |
Christensen, BB | 1 |
Olesen, ML | 1 |
Thomsen, JS | 1 |
Foldager, CB | 1 |
Toh, WS | 1 |
Lim, SK | 1 |
Lind, MC | 1 |
Woods, LM | 1 |
Connelly, CD | 1 |
Doğan, MF | 1 |
Başak Türkmen, N | 1 |
Taşlıdere, A | 1 |
Şahin, Y | 1 |
Çiftçi, O | 1 |
Parsa, FD | 1 |
Cheng, J | 1 |
Stephan, B | 1 |
Castel, N | 1 |
Kim, L | 1 |
Murariu, D | 1 |
Parsa, AA | 1 |
Mulier, J | 1 |
Leung, JM | 1 |
Sands, LP | 1 |
Chen, N | 1 |
Ames, C | 1 |
Berven, S | 1 |
Bozic, K | 1 |
Burch, S | 1 |
Chou, D | 1 |
Covinsky, K | 1 |
Deviren, V | 1 |
Kinjo, S | 1 |
Kramer, JH | 1 |
Ries, M | 1 |
Tay, B | 1 |
Vail, T | 1 |
Weinstein, P | 1 |
Chang, S | 1 |
Meckler, G | 1 |
Newman, S | 1 |
Tsai, T | 1 |
Voss, V | 1 |
Youngblom, E | 1 |
Regan, DW | 1 |
Kashiwagi, D | 1 |
Dougan, B | 1 |
Sundsted, K | 1 |
Mauck, K | 1 |
López-López, J | 1 |
Estrugo-Devesa, A | 1 |
Jane-Salas, E | 1 |
Segura-Egea, JJ | 1 |
Chang, TI | 1 |
Salman, AE | 1 |
Camkıran, A | 1 |
Oğuz, S | 1 |
Dönmez, A | 1 |
Imai, Y | 1 |
Imai, K | 1 |
Kimura, T | 1 |
Horiguchi, T | 1 |
Goyagi, T | 1 |
Saito, H | 1 |
Sato, Y | 1 |
Motoyama, S | 1 |
Nishikawa, T | 1 |
Minamiya, Y | 1 |
Dighe, K | 1 |
Clarke, H | 1 |
McCartney, CJ | 1 |
Wong, CL | 1 |
Mayell, A | 1 |
Srinivasan, I | 1 |
Campbell, F | 1 |
Peliowski, A | 1 |
Yoshitaka, S | 1 |
Egi, M | 1 |
Kanazawa, T | 1 |
Toda, Y | 1 |
Morita, K | 1 |
Rytter, S | 1 |
Stilling, M | 1 |
Munk, S | 1 |
Hansen, TB | 1 |
Park, IJ | 1 |
Kim, G | 1 |
Ko, G | 1 |
Lee, YJ | 1 |
Hwang, SH | 1 |
Guo, R | 1 |
Jacobs, RE | 1 |
Cavalcante, AN | 1 |
Sprung, J | 1 |
Schroeder, DR | 1 |
Weingarten, TN | 1 |
Edwards, LE | 1 |
Hutchison, LB | 1 |
Hornik, CD | 1 |
Smith, PB | 1 |
Cotten, CM | 1 |
Bidegain, M | 1 |
Jacob, S | 1 |
Saha, A | 1 |
Rajabally, Y | 1 |
Garza, I | 1 |
Bang, SR | 1 |
Yu, SK | 1 |
Kim, TH | 1 |
Spreng, UJ | 1 |
Dahl, V | 1 |
Raeder, J | 1 |
Pesonen, A | 1 |
Suojaranta-Ylinen, R | 1 |
Hammarén, E | 1 |
Kontinen, VK | 1 |
Raivio, P | 1 |
Tarkkila, P | 1 |
Rosenberg, PH | 1 |
Silverman, A | 1 |
Samuels, Q | 1 |
Gikas, H | 1 |
Nawras, A | 1 |
Adam, F | 1 |
Bordenave, L | 1 |
Sessler, DI | 1 |
Chauvin, M | 1 |
Behdad, S | 1 |
Ayatollahi, V | 1 |
Bafghi, AT | 1 |
Tezerjani, MD | 1 |
Abrishamkar, M | 1 |
Penumalee, S | 1 |
Kissner, PZ | 1 |
Migdal, SD | 1 |
Guttuso, T | 1 |
Vitticore, P | 1 |
Holloway, RG | 1 |
Lipson, J | 1 |
Lavoie, S | 1 |
Zimmerman, D | 1 |
Son, BC | 1 |
Lee, SW | 1 |
Choi, ES | 1 |
Sung, JH | 1 |
Hong, JT | 1 |
Villevieille, T | 1 |
Boulland, P | 1 |
Plancade, D | 1 |
Steiner, T | 1 |
Chapus, JJ | 1 |
Lagauche, D | 1 |
Allford, MA | 1 |
Davis, JL | 1 |
Posner, LP | 1 |
Elce, Y | 1 |
Ackerman, WE | 1 |
Ahmad, M | 1 |
McGraw, T | 1 |
Stacey, BR | 1 |
Averbuch-Heller, L | 1 |
Stahl, JS | 1 |
Hlavin, ML | 1 |
Leigh, RJ | 1 |
Braverman, DL | 1 |
Slipman, CW | 1 |
Lenrow, DA | 1 |
Pezzuoli, G | 1 |
Spina, GP | 1 |
Vassanelli, P | 1 |
Knutsson, E | 1 |
Lindblom, U | 1 |
Mårtensson, A | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Efficiency of Opioid-free Anesthesia (OFA) in Maxillofacial Surgery[NCT05031676] | 66 participants (Actual) | Interventional | 2019-02-15 | Completed | |||
Opioid-free Anesthesia With a Mixture of Dexmedetomidine-lidocaine-ketamine in Laparoscopic Cholecystectomies[NCT05089526] | 70 participants (Anticipated) | Interventional | 2021-10-11 | Recruiting | |||
Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERies - the PATHFINDER II Study[NCT05279898] | 70 participants (Anticipated) | Interventional | 2023-02-28 | Recruiting | |||
Perioperative Multimodal General Anesthesia Focusing on Specific CNS Targets in Patients Undergoing Cardiac Surgeries[NCT04016740] | Early Phase 1 | 22 participants (Actual) | Interventional | 2019-08-20 | Completed | ||
The Effect of a Mixture of Dexmedetomidine-lidocaine-ketamine in One Syringe Versus Opioids on Recovery Profile and Postoperative Pain After Gynecological Laparoscopic Surgery[NCT04858711] | 60 participants (Anticipated) | Interventional | 2021-04-01 | Recruiting | |||
Clinical Trial of Gabapentin to Decrease Postoperative Delirium and Pain in Surgical Patients[NCT00221338] | Phase 3 | 750 participants (Actual) | Interventional | 2006-01-31 | Completed | ||
Use of Gabapentin as Preanesthetic Medication in Oncologic Children Undergoing in Fast Procedures With Sevofluran[NCT03681574] | Phase 4 | 135 participants (Actual) | Interventional | 2017-07-01 | Completed | ||
Placebo Controlled, Randomized,Gabapentin as Adjuvant for Postoperative Pain in Pediatric Orthopedic Surgery[NCT03005483] | Phase 4 | 40 participants (Actual) | Interventional | 2014-01-31 | Completed | ||
Efficacy of Gabapentin as Adjuvant for Postoperative Pain in Pediatric Thoracic Surgery - a Randomized Quadruple Blind Study[NCT03393702] | Phase 4 | 104 participants (Actual) | Interventional | 2017-05-09 | Completed | ||
The Effect of Preoperative Steroids Injection on Pain and Oedema After Total Knee Arthroplasty . A Double -Blinded Randomized Controlled Study.[NCT04084912] | Phase 3 | 86 participants (Anticipated) | Interventional | 2020-01-01 | Not yet recruiting | ||
Efficacy of Steroids on Functional Outcomes After Musculoskeletal Injuries of the Hand[NCT05003596] | Phase 2/Phase 3 | 60 participants (Anticipated) | Interventional | 2021-09-01 | Not yet recruiting | ||
Analgetic and Anxiolytic Effect of Preoperative Pregabalin in Patients Undergoing Surgery of the Vertebral Columna[NCT00353704] | Phase 4 | 50 participants (Actual) | Interventional | 2005-11-30 | Completed | ||
Peri-Operative Pregabalin for Reducing opIoid Consumption AfTer Cardiac surgEry: A Randomized Trial[NCT04517110] | Phase 3 | 17 participants (Actual) | Interventional | 2021-04-09 | Terminated (stopped due to The COVID-19 pandemic has reduced recruitment such that the study is no longer feasible) | ||
Comparison of Periosteal and Subcutaneous Infusions of Articaine and Bupivacaine in Treatment of Acute Pain After Sternotomy[NCT01536717] | Phase 4 | 36 participants (Actual) | Interventional | 2012-03-31 | Suspended | ||
Pregabalin for the Treatment of Abdominal Pain From Adhesions: Placebo Controlled Trial[NCT00310765] | Phase 4 | 18 participants (Actual) | Interventional | 2006-03-31 | Terminated (stopped due to Study was terminated by the sponsor due to low accrual.) | ||
The Use of Penile Vibratory Stimulation to Decrease Spasticity Following Spinal Cord Injury[NCT00223873] | 30 participants | Interventional | 2002-11-30 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
(NCT00221338)
Timeframe: Typically within the first week after surgery
Intervention | days (Mean) |
---|---|
Gabapentin | 4.4 |
Placebo | 4.1 |
Number of subjects who developed postoperative delirium, as measured by the Confusion Assessment Method, a validated tool for assessing delirium based on DSM-III-R, on any of the first three postoperative days. (NCT00221338)
Timeframe: postoperative days 1, 2 and 3
Intervention | Participants (Count of Participants) |
---|---|
Gabapentin | 84 |
Placebo | 72 |
Postoperative intravenous opioid doses converted to morphine equivalents. Median derived from total opioid doses on first, second and third postoperative days. (NCT00221338)
Timeframe: Study follow up period: postoperative days 1, 2 and 3
Intervention | morphine equivalents, mg (Median) |
---|---|
Gabapentin | 6.7 |
Placebo | 6.7 |
Postoperative pain as measured by Visual Analog Pain scale (0=no pain, 10=worst pain imaginable). (NCT00221338)
Timeframe: Postoperative day 1
Intervention | score on a scale (Mean) |
---|---|
Gabapentin | 4 |
Placebo | 4 |
Postoperative pain as measured by Visual Analog Pain scale (0=no pain, 10=worst pain imaginable). (NCT00221338)
Timeframe: Postoperative day 2
Intervention | score on a scale (Mean) |
---|---|
Gabapentin | 3 |
Placebo | 4 |
Postoperative pain as measured by Visual Analog Pain scale (0=no pain, 10=worst pain imaginable). (NCT00221338)
Timeframe: Postoperative day 3
Intervention | score on a scale (Mean) |
---|---|
Gabapentin | 3 |
Placebo | 3 |
The visual analogue scale (VAS) was used for registration of the pain intensity at rest. The score ranges from 0-100, where 0 means no pain and 100 means maximal pain. Higher values represent a worse outcome. (NCT00353704)
Timeframe: 120 minutes after surgery
Intervention | Units on a scale (Mean) |
---|---|
Pregabalin | 11.7 |
Placebo | 22.5 |
"Patients were equipped with a morphine PCA (patient controlled analgesia) for 24 hours after surgery. So they could administrate morphine intravenously by pressing a button. The sum of morphine was registered as cumulated opioid consumption (milligram)" (NCT00353704)
Timeframe: 240 minutes
Intervention | mg (Mean) |
---|---|
Pregabalin | 7.3 |
Placebo | 16.0 |
Patients were randomized to pregabalin or placebo 75 mg twice a day. Patients were allowed to double the dose on day 3 if adequate pain relief was not obtained. Abdominal pain reduction was measured on a Likert scale. A Likert scale assumes the intensity of pain is linear on a continuum from no pain at level 0 to severe pain at level 10. Patients were required to complete a daily dairy recording pain using the Likert 11-point numeric scale. The primary end point was a positive change in the daily pain diary of 2 points from each patient's baseline at weeks 8 after the completion of the blinded study and at week 12 during the open label portion of the study. After 7 weeks all patients are randomized to study drug pregabalin 150 to 300 mg daily for 4 additional weeks after a one week wash out with no medication. (NCT00310765)
Timeframe: Baseline and week 2 through week 12
Intervention | units on a scale (Mean) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
baseline pain score | week 2 | week 3 | week 4 | week 5 | week 6 | week 7 | week 8 open label with no study medication | week 9 open label | week 10 open label | week 11 open label | week 12 open label | |
Patients Treated With Placebo | 5.8 | 5.22 | 4.64 | 4.84 | 4.32 | 3.88 | 3.92 | 4.13 | 2.21 | 2.27 | 2.23 | 1.13 |
Patients Treated With Pregabalin | 6.15 | 2.87 | 1.88 | 3.31 | 2.72 | 2.49 | 2.53 | 2.46 | 2.06 | 1.84 | 1.46 | 1.68 |
Absolute Improvement in Sleep by assessing Mean Daily sleep interference scores as measured weekly starting at baseline and reported weekly through week 12 excluding the first week. This score is an 11 point scale the documents the pain interference in sleep in the preceding 24 hours. 0 is no interference and 10 is pain completely disrupted sleep in the previous 24 hours. During the study patients recorded a daily sleep interference score based on 11 point scale (0-10) with the higher number being the most sleep interference (NCT00310765)
Timeframe: Baseline and week 2 through week 12
Intervention | units on a scale (Mean) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
baseline | week 2 | week 3 | week 4 | week 5 | week 6 | week 7 | week 8 open label no study medication | week 9 open label | week 10 open label | week 11 open label | week 12 open label | |
Placebo | 4.66 | 3.4 | 3.26 | 3.54 | 3.06 | 2.74 | 3.18 | 3.30 | 1.70 | 1.25 | 1.18 | 0.56 |
Pregabalin | 3.94 | 2.20 | 1.60 | 1.68 | 1.68 | 1.55 | 1.6 | 1.82 | 1.31 | 1.37 | 1.39 | 1.01 |
2 reviews available for gamma-aminobutyric acid and Complication, Postoperative
Article | Year |
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Update in perioperative medicine: practice changing evidence published in 2016.
Topics: Amines; Analgesics; Anticoagulants; Antipsychotic Agents; Arthritis, Rheumatoid; Blood Transfusion; | 2017 |
Does preoperative administration of gabapentin/pregabalin improve postoperative nasal surgery pain?
Topics: Adolescent; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminob | 2016 |
10 trials available for gamma-aminobutyric acid and Complication, Postoperative
Article | Year |
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Perioperative Gabapentin Does Not Reduce Postoperative Delirium in Older Surgical Patients: A Randomized Clinical Trial.
Topics: Aged; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Delirium; Double-Blind Me | 2017 |
Gabapentin premedication for postoperative analgesia and emergence agitation after sevoflurane anesthesia in pediatric patients.
Topics: Amines; Anesthesia, General; Anesthetics, Inhalation; Anti-Anxiety Agents; Child; Child, Preschool; | 2013 |
Perioperative gabapentin and delirium following total knee arthroplasty: a post-hoc analysis of a double-blind randomized placebo-controlled trial.
Topics: Aged; Amines; Analgesics; Arthroplasty, Replacement, Knee; Cyclohexanecarboxylic Acids; Delirium; Do | 2014 |
Analgesic effects of gabapentin after scoliosis surgery in children: a randomized controlled trial.
Topics: Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Cyclohexanecarbox | 2014 |
Analgesic effects of gabapentin after scoliosis surgery in children: a randomized controlled trial.
Topics: Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Cyclohexanecarbox | 2014 |
Analgesic effects of gabapentin after scoliosis surgery in children: a randomized controlled trial.
Topics: Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Cyclohexanecarbox | 2014 |
Analgesic effects of gabapentin after scoliosis surgery in children: a randomized controlled trial.
Topics: Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Cyclohexanecarbox | 2014 |
Analgesic effects of gabapentin after scoliosis surgery in children: a randomized controlled trial.
Topics: Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Cyclohexanecarbox | 2014 |
Analgesic effects of gabapentin after scoliosis surgery in children: a randomized controlled trial.
Topics: Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Cyclohexanecarbox | 2014 |
Analgesic effects of gabapentin after scoliosis surgery in children: a randomized controlled trial.
Topics: Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Cyclohexanecarbox | 2014 |
Analgesic effects of gabapentin after scoliosis surgery in children: a randomized controlled trial.
Topics: Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Cyclohexanecarbox | 2014 |
Analgesic effects of gabapentin after scoliosis surgery in children: a randomized controlled trial.
Topics: Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Cyclohexanecarbox | 2014 |
Can gabapentin help reduce postoperative pain in arthroscopic rotator cuff repair? A prospective, randomized, double-blind study.
Topics: Aged; Amines; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Arthrosc | 2010 |
Effect of a single dose of pregabalin on post-operative pain and pre-operative anxiety in patients undergoing discectomy.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, Intravenous; Anxie | 2011 |
Pregabalin has an opioid-sparing effect in elderly patients after cardiac surgery: a randomized placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Cardiac Surgical Procedures; | 2011 |
Pregabalin has an opioid-sparing effect in elderly patients after cardiac surgery: a randomized placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Cardiac Surgical Procedures; | 2011 |
Pregabalin has an opioid-sparing effect in elderly patients after cardiac surgery: a randomized placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Cardiac Surgical Procedures; | 2011 |
Pregabalin has an opioid-sparing effect in elderly patients after cardiac surgery: a randomized placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Cardiac Surgical Procedures; | 2011 |
Pregabalin has an opioid-sparing effect in elderly patients after cardiac surgery: a randomized placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Cardiac Surgical Procedures; | 2011 |
Pregabalin has an opioid-sparing effect in elderly patients after cardiac surgery: a randomized placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Cardiac Surgical Procedures; | 2011 |
Pregabalin has an opioid-sparing effect in elderly patients after cardiac surgery: a randomized placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Cardiac Surgical Procedures; | 2011 |
Pregabalin has an opioid-sparing effect in elderly patients after cardiac surgery: a randomized placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Cardiac Surgical Procedures; | 2011 |
Pregabalin has an opioid-sparing effect in elderly patients after cardiac surgery: a randomized placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Cardiac Surgical Procedures; | 2011 |
Pregabalin for the treatment of abdominal adhesion pain: a randomized, double-blind, placebo-controlled trial.
Topics: Abdomen; Abdominal Pain; Adult; Analgesics; Chronic Pain; Double-Blind Method; Female; gamma-Aminobu | 2012 |
Effects of a single 1200-mg preoperative dose of gabapentin on anxiety and memory.
Topics: Adult; Aged; Amines; Analgesics; Anesthesia, General; Anti-Anxiety Agents; Anxiety; Cyclohexanecarbo | 2012 |
Effect of gabapentin on postoperative pain and operation complications: a randomized placebo controlled trial.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Amin | 2012 |
25 other studies available for gamma-aminobutyric acid and Complication, Postoperative
Article | Year |
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Topics: Acetic Acid; Albumins; Alkaline Phosphatase; Alkaloids; Amyloid beta-Peptides; Analgesics, Opioid; A | 2021 |
Bilateral Breast Reduction Without Opioid Analgesics: A Comparative Study.
Topics: Adult; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthesia, Local; | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2017 |
Medical treatment of post-dental extraction peripheral painful traumatic trigeminal neuropathy.
Topics: Adrenal Cortex Hormones; Anticonvulsants; Diagnosis, Differential; Drug Therapy, Combination; Female | 2013 |
Evaluation of postoperative pregabalin for attenuation of postoperative shoulder pain after thoracotomy in patients with lung cancer, a preliminary result.
Topics: Adult; Aged; Analgesics; Female; gamma-Aminobutyric Acid; Humans; Lung Neoplasms; Male; Middle Aged; | 2015 |
The association of plasma gamma-aminobutyric acid concentration with postoperative delirium in critically ill patients.
Topics: Critical Illness; Delirium; gamma-Aminobutyric Acid; Humans; Multivariate Analysis; Postoperative Co | 2014 |
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, | 2017 |
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, | 2017 |
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, | 2017 |
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, | 2017 |
Management of Peripheral Entrapment Neuropathy Following Abdominoplasty: A Case Report.
Topics: Abdominal Pain; Abdominoplasty; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Foll | 2016 |
Multimodal Analgesic Therapy With Gabapentin and Its Association With Postoperative Respiratory Depression.
Topics: Adult; Aged; Amines; Analgesia; Analgesics; Analgesics, Opioid; Combined Modality Therapy; Critical | 2017 |
A case of infant delirium in the neonatal intensive care unit.
Topics: Amines; Analgesics, Opioid; Anti-Anxiety Agents; Cardiac Catheterization; Cyclohexanecarboxylic Acid | 2017 |
Post-traumatic short-lasting unilateral headache with cranial autonomic symptoms (SUNA).
Topics: Accidents, Traffic; Adult; Amines; Carbamazepine; Conjunctiva; Cyclohexanecarboxylic Acids; Facial P | 2008 |
The trigeminal trophic syndrome: an unusual cause of face pain, dysaesthesias, anaesthesia and skin/soft tissue lesions.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Child; Cyclohexanecarboxylic Acids; Erythema; Fa | 2008 |
Gabapentin-induced hypoglycemia in a long-term peritoneal dialysis patient.
Topics: Acetates; Amines; C-Peptide; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Aci | 2003 |
Responsiveness of life-threatening refractory emesis to gabapentin-scopolamine therapy following posterior fossa surgery. Case report.
Topics: Amines; Antiemetics; Cholesteatoma; Cranial Fossa, Posterior; Cyclohexanecarboxylic Acids; Drug Ther | 2005 |
Gabapentin-induced myopathy in 2 patients on short daily hemodialysis.
Topics: Adult; Amines; Anticonvulsants; Atorvastatin; Calcium Channels; Comorbidity; Cyclohexanecarboxylic A | 2005 |
Motor cortex stimulation for central pain following a traumatic brain injury.
Topics: Accidental Falls; Adult; Amines; Amitriptyline; Analgesics, Non-Narcotic; Aphasia, Broca; Brain Inju | 2006 |
[This is the anaesthetist's fault! (About the post-anaesthetic consultation)].
Topics: Accidental Falls; Acromioclavicular Joint; Adult; Amines; Analgesia; Anesthesia, Local; Anesthesiolo | 2007 |
Prolonged myotonia and dystonia after general anaesthesia in a patient taking gabapentin.
Topics: Amines; Analgesics; Anesthetics, General; Cyclohexanecarboxylic Acids; Drug Interactions; Dystonia; | 2007 |
Gabapentin for the treatment of neuropathic pain in a pregnant horse.
Topics: Amines; Analgesics; Animals; Colic; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobuty | 2007 |
Recurrent postoperative CRPS I in patients with abnormal preoperative sympathetic function.
Topics: Adult; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Autonomic Nerve Block; Carpal Tu | 2008 |
Gabapentin for treatment of neuropathic pain in a 12-year-old girl.
Topics: Acetates; Amines; Child; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; H | 1998 |
Square-wave jerks induced by pallidotomy in parkinsonian patients.
Topics: Adult; Aged; Female; Fixation, Ocular; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Male; Neura | 1999 |
Using gabapentin to treat failed back surgery syndrome caused by epidural fibrosis: A report of 2 cases.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diagnosis | 2001 |
[Current aspects of the surgery of portal hypertension (PH)].
Topics: Animals; Brain; Brain Diseases; Catecholamines; Enzymes; Esophageal and Gastric Varices; gamma-Amino | 1975 |
Plasma and cerebrospinal fluid levels of baclofen (Lioresal) at optimal therapeutic responses in spastic paresis.
Topics: Adolescent; Adult; Aged; Aminobutyrates; Cold Temperature; Female; gamma-Aminobutyric Acid; Humans; | 1974 |