gamma-aminobutyric acid has been researched along with Colorectal Neoplasms in 4 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-Fluorouracil (5-FU) is an essential drug in systemic chemotherapy treatments for colorectal cancer (CRC)." | 4.02 | GABA-producing Lactobacillus plantarum inhibits metastatic properties and induces apoptosis of 5-FU-resistant colorectal cancer cells via GABA ( An, J; Ha, EM; Seok, H, 2021) |
| "Thirteen patients with metastatic colorectal cancer who suffered from oxaliplatin-induced sensory neuropathy were evaluated to determine the neuropathy Grade before and after the administration of pregabalin." | 3.79 | [Promising effects of pregabalin in the treatment of oxaliplatin-induced sensory neuropathy in patients with colorectal carcinoma]. ( Hasegawa, T; Hirakawa, K; Hirakawa, T; Inoue, T; Maeda, K; Nagahara, H; Noda, E; Shibutani, M, 2013) |
| "5-Fluorouracil (5-FU) is an essential drug in systemic chemotherapy treatments for colorectal cancer (CRC)." | 1.62 | GABA-producing Lactobacillus plantarum inhibits metastatic properties and induces apoptosis of 5-FU-resistant colorectal cancer cells via GABA ( An, J; Ha, EM; Seok, H, 2021) |
| " In this study, pregabalin was shown to positively impact sensory neuropathy resulting from oxaliplatin treatment and to enable the long-term use of oxaliplatin-based chemotherapy." | 1.39 | [Promising effects of pregabalin in the treatment of oxaliplatin-induced sensory neuropathy in patients with colorectal carcinoma]. ( Hasegawa, T; Hirakawa, K; Hirakawa, T; Inoue, T; Maeda, K; Nagahara, H; Noda, E; Shibutani, M, 2013) |
| "Thirteen patients with metastatic colorectal cancer who suffered from oxaliplatin-induced sensory neuropathy were evaluated to determine the neuropathy Grade before and after the administration of pregabalin." | 1.39 | [Promising effects of pregabalin in the treatment of oxaliplatin-induced sensory neuropathy in patients with colorectal carcinoma]. ( Hasegawa, T; Hirakawa, K; Hirakawa, T; Inoue, T; Maeda, K; Nagahara, H; Noda, E; Shibutani, M, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, H | 1 |
| Qin, XK | 1 |
| Yin, KW | 1 |
| Li, ZM | 1 |
| Ni, ED | 1 |
| Yang, JM | 1 |
| Liu, XH | 1 |
| Zhou, AJ | 1 |
| Li, SJ | 1 |
| Gao, TM | 1 |
| Li, Y | 1 |
| Li, JM | 1 |
| An, J | 1 |
| Seok, H | 1 |
| Ha, EM | 1 |
| Nagahara, H | 1 |
| Noda, E | 1 |
| Maeda, K | 1 |
| Inoue, T | 1 |
| Hirakawa, T | 1 |
| Hasegawa, T | 1 |
| Shibutani, M | 1 |
| Hirakawa, K | 1 |
| Mitchell, PL | 1 |
| Goldstein, D | 1 |
| Michael, M | 1 |
| Beale, P | 1 |
| Friedlander, M | 1 |
| Zalcberg, J | 1 |
| White, S | 1 |
| Thomson, JA | 1 |
| Clarke, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Kinetics of Endocannabinoids in Patients With Chemotherapy Induced Peripheral Neuropathy by Using a Portable Metered-Dose Cannabis Inhaler[NCT04376437] | 40 participants (Anticipated) | Interventional | 2022-03-15 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for gamma-aminobutyric acid and Colorectal Neoplasms
| Article | Year |
|---|---|
EphB6 deficiency in intestinal neurons promotes tumor growth in colorectal cancer by neurotransmitter GABA signaling.
Topics: Animals; Cell Communication; Colorectal Neoplasms; gamma-Aminobutyric Acid; Humans; Intestines; Mice | 2023 |
GABA-producing Lactobacillus plantarum inhibits metastatic properties and induces apoptosis of 5-FU-resistant colorectal cancer cells via GABA
Topics: Antineoplastic Agents; Apoptosis; Colorectal Neoplasms; Drug Resistance, Neoplasm; Fluorouracil; gam | 2021 |
[Promising effects of pregabalin in the treatment of oxaliplatin-induced sensory neuropathy in patients with colorectal carcinoma].
Topics: Adult; Aged; Antineoplastic Agents; Colorectal Neoplasms; Female; gamma-Aminobutyric Acid; Humans; M | 2013 |
Addition of gabapentin to a modified FOLFOX regimen does not reduce oxaliplatin-induced neurotoxicity.
Topics: Amines; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Cyclohexanecarboxylic | 2006 |