gamma-aminobutyric acid has been researched along with Chromosome Deletion in 6 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Chromosome Deletion: Actual loss of portion of a chromosome.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Plasma gamma-aminobutyric acid (GABA) levels were measured in 14 subjects with Prader-Willi syndrome, 9 subjects with Angelman syndrome, and matched control subjects." | 9.08 | Elevated plasma gamma-aminobutyric acid (GABA) levels in individuals with either Prader-Willi syndrome or Angelman syndrome. ( Butler, MG; Ebert, MH; Schmidt, DE; Thompson, T, 1997) |
| "Plasma gamma-aminobutyric acid (GABA) levels were measured in 14 subjects with Prader-Willi syndrome, 9 subjects with Angelman syndrome, and matched control subjects." | 5.08 | Elevated plasma gamma-aminobutyric acid (GABA) levels in individuals with either Prader-Willi syndrome or Angelman syndrome. ( Butler, MG; Ebert, MH; Schmidt, DE; Thompson, T, 1997) |
| "Genetic predisposition to autism has been demonstrated from families and twin studies." | 2.44 | [Autism, chromosome 15 and the GAbaergic dysfunction hypothesis]. ( Delgado-Luengo, W; Hernández, ML; Solís-Añez, E, 2007) |
| "Autism is a complex neurodevelopmental disorder characterized by impairment of social interaction, language, communication, and stereotyped, repetitive behavior." | 2.44 | [Autism, chromosome 15 and the GAbaergic dysfunction hypothesis]. ( Delgado-Luengo, W; Hernández, ML; Solís-Añez, E, 2007) |
| " In contrast, biochemical study (based on dosage of plasma levels of GABA and diazepam binding inhibitor, an endogenous ligand of GABAA and peripheral benzodiazepine receptors, showed contradictory results: patients with Angelman's syndrome showed significantly higher levels of GABA and diazepam binding inhibitor than patients without neurologic impairment but significantly lower levels than epileptic controls." | 1.32 | Peripheral markers of the gamma-aminobutyric acid (GABA)ergic system in Angelman's syndrome. ( Borgatti, R; Cogliati, T; Elia, M; Ferrarese, C; Grasso, R; Musumeci, SA; Passoni, D; Piccinelli, P; Raggi, ME; Romeo, A; Valseriati, D; Viri, M, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Rein, B | 1 |
| Tan, T | 1 |
| Yang, F | 1 |
| Wang, W | 1 |
| Williams, J | 1 |
| Zhang, F | 1 |
| Mills, A | 1 |
| Yan, Z | 1 |
| Borgatti, R | 1 |
| Piccinelli, P | 1 |
| Passoni, D | 1 |
| Romeo, A | 1 |
| Viri, M | 1 |
| Musumeci, SA | 1 |
| Elia, M | 1 |
| Cogliati, T | 1 |
| Valseriati, D | 1 |
| Grasso, R | 1 |
| Raggi, ME | 1 |
| Ferrarese, C | 1 |
| Schuckit, MA | 1 |
| Kelsoe, JR | 1 |
| Braff, DL | 1 |
| Wilhelmsen, KC | 1 |
| Solís-Añez, E | 1 |
| Delgado-Luengo, W | 1 |
| Hernández, ML | 1 |
| Ebert, MH | 1 |
| Schmidt, DE | 1 |
| Thompson, T | 1 |
| Butler, MG | 1 |
| Jackson, FR | 1 |
| Newby, LM | 1 |
| Kulkarni, SJ | 1 |
1 review available for gamma-aminobutyric acid and Chromosome Deletion
| Article | Year |
|---|---|
[Autism, chromosome 15 and the GAbaergic dysfunction hypothesis].
Topics: Angelman Syndrome; Animals; Autistic Disorder; Chromosome Deletion; Chromosome Mapping; Chromosomes, | 2007 |
1 trial available for gamma-aminobutyric acid and Chromosome Deletion
| Article | Year |
|---|---|
Elevated plasma gamma-aminobutyric acid (GABA) levels in individuals with either Prader-Willi syndrome or Angelman syndrome.
Topics: Adolescent; Adult; Angelman Syndrome; Child; Child, Preschool; Chromosome Deletion; Chromosomes, Hum | 1997 |
4 other studies available for gamma-aminobutyric acid and Chromosome Deletion
| Article | Year |
|---|---|
Reversal of synaptic and behavioral deficits in a 16p11.2 duplication mouse model via restoration of the GABA synapse regulator Npas4.
Topics: Animals; Autism Spectrum Disorder; Basic Helix-Loop-Helix Transcription Factors; Chromosome Deletion | 2021 |
Peripheral markers of the gamma-aminobutyric acid (GABA)ergic system in Angelman's syndrome.
Topics: Adolescent; Adult; Angelman Syndrome; Child; Child, Preschool; Chromosome Banding; Chromosome Deleti | 2003 |
Some possible genetic parallels across alcoholism, bipolar disorder and schizophrenia.
Topics: Alcoholism; Bipolar Disorder; Catecholamines; Chromosome Deletion; Chromosomes, Human, Pair 10; Chro | 2003 |
Drosophila GABAergic systems: sequence and expression of glutamic acid decarboxylase.
Topics: Amino Acid Sequence; Animals; Base Sequence; Central Nervous System; Chromosome Deletion; Cloning, M | 1990 |