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gamma-aminobutyric acid and Cerebral Palsy

gamma-aminobutyric acid has been researched along with Cerebral Palsy in 16 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Cerebral Palsy: A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)

Research Excerpts

ExcerptRelevanceReference
"Cerebral palsy is among the most frequent disorders of the growing locomotor apparatus during childhood."2.41[Botulinum toxin type A in the treatment plan for cerebral palsy]. ( Strobl, W, 2001)
"Weakness as well as spasticity due to lack of selective neuronal control causes functional impairment and additional mechanisms of compensation, retardation of motor development, secondary deformities of muscles and soft tissues due to a failure of muscle growth, subluxation/dislocation of joints, early osteoarthritis, and pain."2.41[Botulinum toxin type A in the treatment plan for cerebral palsy]. ( Strobl, W, 2001)
"Epilepsy is common in individuals who are mentally retarded and/or otherwise multiply handicapped."2.39The role of the old and the new antiepileptic drugs in special populations: mental and multiple handicaps. ( Mattson, RH, 1996)
"An animal model of chronic spasticity would be valuable."2.38The spastic mouse. And the search for an animal model of spasticity in human beings. ( Rang, M; Wright, J, 1990)
"Mean pre-withdrawal pregabalin dosage was 386 mg/day, decreasing to 70 mg/day at mean lowest dosage."1.39Spasticity increases during pregabalin withdrawal. ( Baguley, IJ; Braid, JJ; Kirker, SG, 2013)
"Median subjective spasticity scores increased from 4 at baseline to 6 at lowest dose (p < 0."1.39Spasticity increases during pregabalin withdrawal. ( Baguley, IJ; Braid, JJ; Kirker, SG, 2013)
"Six children with cerebral palsy are presented who developed neuropathic pain following multilevel orthopedic surgery."1.33Neuropathic pain following multilevel surgery in children with cerebral palsy: a case series and review. ( Lauder, GR; White, MC, 2005)
"Twenty children had spastic diplegia and three had quadriplegia."1.33Metabolite profile in the basal ganglia of children with cerebral palsy: a proton magnetic resonance spectroscopy study. ( Kubas, B; Kulak, W; Smigielska-Kuzia, J; Sobaniec, W; Walecki, J, 2006)
"EEG showed typical hypsarrhythmia in 8 cases, asymmetrical hypsarrhythmia in 1 case and modified hypsarrhythmia in another case."1.30[West's syndrome in patients with cerebral paralysis and periventricular leukomalacia: a good response to treatment]. ( Caraballo, R; Cersósimo, R; Fejerman, N; Intruvini, S; Pociecha, J, 1997)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19905 (31.25)18.7374
1990's3 (18.75)18.2507
2000's6 (37.50)29.6817
2010's2 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Batysheva, TT1
Platonova, AN1
Chebanenko, NV1
Bykova, OV1
Braid, JJ1
Kirker, SG1
Baguley, IJ1
Arvio, M1
Merikanto, J1
SHIMIZU, S1
BERTAMINO, F1
VENTO, R1
Strobl, W1
Lauder, GR2
White, MC1
Nordmann, GR1
Grier, DJ1
Kulak, W1
Sobaniec, W1
Smigielska-Kuzia, J1
Kubas, B1
Walecki, J1
Mattson, RH1
Caraballo, R1
Cersósimo, R1
Intruvini, S1
Pociecha, J1
Fejerman, N1
Krach, LE1
Gershman, RN1
Vasilenko, MA1
Iliushina, GG1
Iakimenko, GD1
Iakovleva, SM1
Wright, J1
Rang, M1
Lipkin, PH1
Roe, CR1
Goodman, SI1
Batshaw, ML1
Sazonova, NS1
Balashova, EG1

Reviews

4 reviews available for gamma-aminobutyric acid and Cerebral Palsy

ArticleYear
[Botulinum toxin type A in the treatment plan for cerebral palsy].
    Wiener klinische Wochenschrift, 2001, Volume: 113 Suppl 4

    Topics: Activities of Daily Living; Adolescent; Adult; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; C

2001
The role of the old and the new antiepileptic drugs in special populations: mental and multiple handicaps.
    Epilepsia, 1996, Volume: 37 Suppl 6

    Topics: Acetates; Amines; Anticonvulsants; Cerebral Palsy; Cyclohexanecarboxylic Acids; Disabled Persons; Dr

1996
Pharmacotherapy of spasticity: oral medications and intrathecal baclofen.
    Journal of child neurology, 2001, Volume: 16, Issue:1

    Topics: Acetates; Administration, Oral; Amines; Anti-Anxiety Agents; Baclofen; Benzodiazepines; Cerebral Pal

2001
The spastic mouse. And the search for an animal model of spasticity in human beings.
    Clinical orthopaedics and related research, 1990, Issue:253

    Topics: Animals; Cerebral Palsy; Disease Models, Animal; Electric Stimulation; gamma-Aminobutyric Acid; Huma

1990

Trials

2 trials available for gamma-aminobutyric acid and Cerebral Palsy

ArticleYear
[Management of cognitive impairment in children and adolescents with cerebral palsy treated with pantocalcin].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2013, Volume: 113, Issue:9

    Topics: Adolescent; Anxiety; Attention; Cerebral Palsy; Child; Cognition; Female; gamma-Aminobutyric Acid; H

2013
[Gammalon in the rehabilitation in infantile cerebral palsy].
    Pediatriia akusherstvo i ginekologiia, 1977, Issue:6

    Topics: Aminobutyrates; Cerebral Palsy; Child; Clinical Trials as Topic; Drug Evaluation; Electroencephalogr

1977

Other Studies

10 other studies available for gamma-aminobutyric acid and Cerebral Palsy

ArticleYear
Spasticity increases during pregabalin withdrawal.
    Brain injury, 2013, Volume: 27, Issue:1

    Topics: Analgesics; Anticonvulsants; Brain Injuries; Cerebral Palsy; Drug Administration Schedule; Female; g

2013
[A relief from neural pain--gabapentin helped against hip ache in a girl with cerebral palsy].
    Duodecim; laaketieteellinen aikakauskirja, 2001, Volume: 117, Issue:14

    Topics: Acetates; Adolescent; Amines; Analgesics; Arthralgia; Cerebral Palsy; Cyclohexanecarboxylic Acids; F

2001
[Use of aminobutyric acid (GABA) in congenital oligophrenia and in infantile cerebral paralysis].
    Revista brasileira de cirurgia, 1961, Volume: 42

    Topics: Amino Acids; Aminobutyrates; Antifibrinolytic Agents; Cerebral Palsy; Diet, Reducing; gamma-Aminobut

1961
[GABOB IN PEDIATRICS. CLINICAL AND ELECTROENCEPHALOGRAPHIC STUDY OF 28 CASES].
    Minerva pediatrica, 1964, Jun-30, Volume: 16

    Topics: Adolescent; Aminobutyrates; Barbiturates; Brain Injuries; Cerebral Palsy; Child; Electroencephalogra

1964
Neuropathic pain following multilevel surgery in children with cerebral palsy: a case series and review.
    Paediatric anaesthesia, 2005, Volume: 15, Issue:5

    Topics: Adolescent; Amines; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Cerebral Palsy; Chi

2005
Computed tomography guided lumbar sympathetic block for complex regional pain syndrome in a child: a case report and review.
    European journal of pain (London, England), 2006, Volume: 10, Issue:5

    Topics: Amines; Amitriptyline; Analgesics; Anesthetics, Local; Antidepressive Agents, Tricyclic; Autonomic N

2006
Metabolite profile in the basal ganglia of children with cerebral palsy: a proton magnetic resonance spectroscopy study.
    Developmental medicine and child neurology, 2006, Volume: 48, Issue:4

    Topics: Adolescent; Apgar Score; Aspartic Acid; Basal Ganglia; Cerebral Palsy; Child; Child, Preschool; Chol

2006
[West's syndrome in patients with cerebral paralysis and periventricular leukomalacia: a good response to treatment].
    Revista de neurologia, 1997, Volume: 25, Issue:145

    Topics: Anticonvulsants; Atrophy; Cerebral Palsy; Cerebral Ventricles; Child; Child, Preschool; Female; gamm

1997
A case of glutaric acidemia type I: effect of riboflavin and carnitine.
    The Journal of pediatrics, 1988, Volume: 112, Issue:1

    Topics: Amino Acid Metabolism, Inborn Errors; Basal Ganglia Diseases; Carnitine; Cerebral Palsy; Child, Pres

1988
[Experience with clinical use of the drug gammalon in children with cerebral palsy].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1974, Volume: 74, Issue:10

    Topics: Adolescent; Aminobutyrates; Cerebral Palsy; Child; Child, Preschool; Electromyography; Feeding and E

1974