gamma-aminobutyric acid has been researched along with Catatonic Rigidity in 21 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "GABA levels were unaltered by Parkinson's disease, clinical phenotype, or medication." | 1.56 | GABAergic changes in the thalamocortical circuit in Parkinson's disease. ( Cools, R; den Ouden, HEM; Dirkx, MFM; Helmich, RC; Scheenen, TWJ; Toni, I; van Asten, JJA; van Nuland, AJM; Zach, H, 2020) |
| "Parkinson's disease is characterized by bradykinesia, rigidity, and tremor." | 1.56 | GABAergic changes in the thalamocortical circuit in Parkinson's disease. ( Cools, R; den Ouden, HEM; Dirkx, MFM; Helmich, RC; Scheenen, TWJ; Toni, I; van Asten, JJA; van Nuland, AJM; Zach, H, 2020) |
| " In addition the optimal time frame for cell grafting after ischemia and the optimal dosing of grafted cells were also studied." | 1.34 | Functional recovery in rats with ischemic paraplegia after spinal grafting of human spinal stem cells. ( Cizkova, D; Hazel, T; Hefferan, MP; Johe, K; Kakinohana, O; Kucharova, K; Marsala, M; Marsala, S, 2007) |
| "Transient spinal cord ischemia in humans can lead to the development of permanent paraplegia with prominent spasticity and rigidity." | 1.34 | Functional recovery in rats with ischemic paraplegia after spinal grafting of human spinal stem cells. ( Cizkova, D; Hazel, T; Hefferan, MP; Johe, K; Kakinohana, O; Kucharova, K; Marsala, M; Marsala, S, 2007) |
| "Spinal cord ischemia was induced for 10 min using aortic occlusion and systemic hypotension." | 1.34 | Functional recovery in rats with ischemic paraplegia after spinal grafting of human spinal stem cells. ( Cizkova, D; Hazel, T; Hefferan, MP; Johe, K; Kakinohana, O; Kucharova, K; Marsala, M; Marsala, S, 2007) |
| "We report the successful management of anesthesia in a patient with stiff-person syndrome (SPS) undergoing a thymectomy using a volatile anesthetic combined with epidural anesthesia." | 1.34 | Considerations for general anesthesia combined with epidural anesthesia in a patient with stiff-person syndrome. ( Hara, K; Horishita, T; Sata, T; Yamamoto, K, 2007) |
| "Transient spinal cord ischemia may lead to a progressive degeneration of spinal interneurons and subsequently to increased hind limb motor tone." | 1.33 | Development of GABA-sensitive spasticity and rigidity in rats after transient spinal cord ischemia: a qualitative and quantitative electrophysiological and histopathological study. ( Galik, J; Hefferan, MP; Kakinohana, M; Kakinohana, O; Marsala, J; Marsala, M; Nakamura, S; Tomori, Z; Yaksh, TL, 2006) |
| "We also characterized changes in the Huntington's disease patients according to pathological grade, since this may be a confounding factor." | 1.29 | Neurochemical substrates of rigidity and chorea in Huntington's disease. ( Beal, MF; Storey, E, 1993) |
| "Huntington's disease is a progressive degenerative neurological disorder which produces a characteristic movement disorder termed chorea." | 1.29 | Neurochemical substrates of rigidity and chorea in Huntington's disease. ( Beal, MF; Storey, E, 1993) |
| "The loss of this action would cause muscular rigidity and motor asymmetry." | 1.29 | Appearance of EMG activity and motor asymmetry after unilateral lesions of the dopaminergic innervation to the subthalamic nucleus in the rat. ( Aceves, J; Flores, G; Rosales, MG; Sierra, A; Valencia, J, 1993) |
| "To study MPTP-induced muscular rigidity, we try to detect the changes of both dopamine (DA) and GABA within rat striatums by immunohistochemical means." | 1.28 | Immunohistochemical detection of GABA in rat striatum by intraperitoneal injection of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine). ( Kawana, E; Yamamoto, C, 1991) |
| "Stiff-man syndrome is a rare disorder of the central nervous system consisting of progressive, fluctuating muscle rigidity with painful spasms." | 1.27 | Autoantibodies to glutamic acid decarboxylase in a patient with stiff-man syndrome, epilepsy, and type I diabetes mellitus. ( Comi, GC; De Camilli, P; Denis-Donini, S; Folli, F; Pozza, G; Solimena, M; Vicari, AM, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (33.33) | 18.7374 |
| 1990's | 6 (28.57) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| van Nuland, AJM | 1 |
| den Ouden, HEM | 1 |
| Zach, H | 1 |
| Dirkx, MFM | 1 |
| van Asten, JJA | 1 |
| Scheenen, TWJ | 1 |
| Toni, I | 1 |
| Cools, R | 1 |
| Helmich, RC | 1 |
| Dayalu, P | 1 |
| Teener, JW | 1 |
| Ali, F | 1 |
| Rowley, M | 1 |
| Jayakrishnan, B | 1 |
| Teuber, S | 1 |
| Gershwin, ME | 1 |
| Mackay, IR | 1 |
| Gazulla Abío, J | 2 |
| Benavente Aguilar, I | 2 |
| Capablo Liesa, JL | 2 |
| Kakinohana, O | 2 |
| Hefferan, MP | 2 |
| Nakamura, S | 1 |
| Kakinohana, M | 1 |
| Galik, J | 1 |
| Tomori, Z | 1 |
| Marsala, J | 1 |
| Yaksh, TL | 1 |
| Marsala, M | 2 |
| Cizkova, D | 1 |
| Kucharova, K | 1 |
| Marsala, S | 1 |
| Johe, K | 1 |
| Hazel, T | 1 |
| Yamamoto, K | 1 |
| Hara, K | 1 |
| Horishita, T | 1 |
| Sata, T | 1 |
| Turski, L | 4 |
| Havemann, U | 2 |
| Kuschinsky, K | 2 |
| Storey, E | 1 |
| Beal, MF | 1 |
| Berthier, M | 1 |
| Oriot, D | 1 |
| Bonneau, D | 1 |
| Jaeken, J | 1 |
| Flores, G | 1 |
| Valencia, J | 1 |
| Rosales, MG | 1 |
| Sierra, A | 1 |
| Aceves, J | 1 |
| Tijssen, MA | 1 |
| Schoemaker, HC | 1 |
| Edelbroek, PJ | 1 |
| Roos, RA | 1 |
| Cohen, AF | 1 |
| van Dijk, JG | 1 |
| Yamamoto, C | 1 |
| Kawana, E | 1 |
| Solimena, M | 2 |
| Folli, F | 2 |
| Aparisi, R | 1 |
| Pozza, G | 2 |
| De Camilli, P | 2 |
| Schwarz, M | 3 |
| Ikonomidou, C | 1 |
| Klockgether, T | 2 |
| Ellenbroek, B | 3 |
| Sontag, KH | 2 |
| Cools, A | 1 |
| Denis-Donini, S | 1 |
| Comi, GC | 1 |
| Vicari, AM | 1 |
| Gol'dblat, IuV | 1 |
| Lapin, IP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Efficacy of High-Dose Intravenous Immunoglobulin Therapy in Patients With Stiff-Man Syndrome: A Double-Blind, Placebo-Controlled Trial[NCT00001550] | Phase 1 | 20 participants | Interventional | 1996-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for gamma-aminobutyric acid and Catatonic Rigidity
| Article | Year |
|---|---|
Stiff Person syndrome and other anti-GAD-associated neurologic disorders.
Topics: Autoantibodies; Central Nervous System; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hu | 2012 |
Stiff-person syndrome (SPS) and anti-GAD-related CNS degenerations: protean additions to the autoimmune central neuropathies.
Topics: Autoantibodies; Central Nervous System; Diabetes Mellitus, Type 1; Epilepsy; GABAergic Neurons; gamm | 2011 |
1 trial available for gamma-aminobutyric acid and Catatonic Rigidity
| Article | Year |
|---|---|
The effects of clonazepam and vigabatrin in hyperekplexia.
Topics: Acoustic Stimulation; Adult; Anticonvulsants; Clonazepam; Cross-Over Studies; Double-Blind Method; E | 1997 |
18 other studies available for gamma-aminobutyric acid and Catatonic Rigidity
| Article | Year |
|---|---|
GABAergic changes in the thalamocortical circuit in Parkinson's disease.
Topics: Aged; Creatine; Dopamine Agents; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectro | 2020 |
[Progressive encephalomyelitis with rigidity responsive to gabapentin: a pharmacological update].
Topics: Amines; Antiparkinson Agents; Clonidine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Dr | 2004 |
Development of GABA-sensitive spasticity and rigidity in rats after transient spinal cord ischemia: a qualitative and quantitative electrophysiological and histopathological study.
Topics: Acetyltransferases; Analysis of Variance; Animals; Baclofen; Dose-Response Relationship, Radiation; | 2006 |
Functional recovery in rats with ischemic paraplegia after spinal grafting of human spinal stem cells.
Topics: Adult; Animals; Astrocytes; Cell Proliferation; Cell Survival; Cells, Cultured; Evoked Potentials, M | 2007 |
Considerations for general anesthesia combined with epidural anesthesia in a patient with stiff-person syndrome.
Topics: Aged; Anesthesia, Epidural; Anesthesia, General; gamma-Aminobutyric Acid; Humans; Male; Muscle Rigid | 2007 |
Evidence for functional interactions of morphine in substantia nigra and striatum in relation to muscular rigidity in rats.
Topics: Animals; Corpus Striatum; Electromyography; gamma-Aminobutyric Acid; Male; Morphine; Muscle Rigidity | 1982 |
GABAergic mechanisms in mediating muscular rigidity, catalepsy and postural asymmetry in rats: differences between dorsal and ventral striatum.
Topics: Animals; Catalepsy; Corpus Striatum; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Muscle Rigidit | 1984 |
Neurochemical substrates of rigidity and chorea in Huntington's disease.
Topics: Adolescent; Adult; Aged; Basal Ganglia; Child; Enkephalin, Methionine; Female; gamma-Aminobutyric Ac | 1993 |
Does a mutation of the glycine receptor modify GABA metabolism in startle disease?
Topics: gamma-Aminobutyric Acid; Humans; Infant; Muscle Rigidity; Point Mutation; Receptors, Glycine; Reflex | 1995 |
Appearance of EMG activity and motor asymmetry after unilateral lesions of the dopaminergic innervation to the subthalamic nucleus in the rat.
Topics: Animals; Bicuculline; Dopamine; Electromyography; gamma-Aminobutyric Acid; Male; Methamphetamine; Mo | 1993 |
[Progressive encephalomyelitis with rigidity. Clinical and electrophysiological aspects].
Topics: Acetates; Aged; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Electrophysiology; Enceph | 2001 |
Immunohistochemical detection of GABA in rat striatum by intraperitoneal injection of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine).
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dopamine; gamma-Aminobutyric Acid; Immunoenzy | 1991 |
Autoantibodies to GABA-ergic neurons and pancreatic beta cells in stiff-man syndrome.
Topics: Autoantibodies; Autoantigens; Autoimmune Diseases; Brain; Central Nervous System Diseases; Cerebrosp | 1990 |
The role of striatal cholinergic mechanisms for the development of limb rigidity: an electromyographic study in rats.
Topics: Animals; Bethanechol; Bethanechol Compounds; Brain Mapping; Cholinergic Fibers; Corpus Striatum; Ele | 1986 |
The importance of the striato-nigro-collicular pathway in the expression of haloperidol-induced tonic electromyographic activity.
Topics: Animals; Brain Mapping; Corpus Striatum; Electromyography; gamma-Aminobutyric Acid; Haloperidol; Mal | 1985 |
Distinct sites of functional interaction between dopamine, acetylcholine and gamma-aminobutyrate within the neostriatum: an electromyographic study in rats.
Topics: Acetylcholine; Animals; Corpus Striatum; Dopamine; Electromyography; gamma-Aminobutyric Acid; Male; | 1986 |
Autoantibodies to glutamic acid decarboxylase in a patient with stiff-man syndrome, epilepsy, and type I diabetes mellitus.
Topics: Autoantibodies; Autoimmune Diseases; Brain; Diabetes Mellitus, Type 1; Epilepsy; Female; gamma-Amino | 1988 |
[Phenibut potentiation of the therapeutic action of antiparkinson agents].
Topics: Adult; Aged; Antiparkinson Agents; Basal Ganglia Diseases; Drug Therapy, Combination; Follow-Up Stud | 1986 |