Page last updated: 2024-10-16

gamma-aminobutyric acid and Catatonia

gamma-aminobutyric acid has been researched along with Catatonia in 17 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Catatonia: A neuropsychiatric disorder characterized by one or more of the following essential features: immobility, mutism, negativism (active or passive refusal to follow commands), mannerisms, stereotypies, posturing, grimacing, excitement, echolalia, echopraxia, muscular rigidity, and stupor; sometimes punctuated by sudden violent outbursts, panic, or hallucinations. This condition may be associated with psychiatric illnesses (e.g., SCHIZOPHRENIA; MOOD DISORDERS) or organic disorders (NEUROLEPTIC MALIGNANT SYNDROME; ENCEPHALITIS, etc.). (From DSM-IV, 4th ed, 1994; APA, Thesaurus of Psychological Index Terms, 1994)

Research Excerpts

ExcerptRelevanceReference
" valproate) were studied in rats against perphenazine-induced catatonia."7.67GABAergic, dopaminergic and cholinergic interactions in perphenazine-induced catatonia in rats. ( Garg, SK; Kulkarni, SK; Mathur, VS; Shukla, VK, 1985)
" The effects of electroconvulsive seizures--the experimental analogue of ECT--should also be tested in gamma-aminobutyric acid-ergic animal models of autistic regression, autism, catatonia, and other neurodevelopmental disorders."4.83Are autistic and catatonic regression related? A few working hypotheses involving gaba, Purkinje cell survival, neurogenesis, and ECT. ( Dhossche, DM; Rout, U, 2006)
" valproate) were studied in rats against perphenazine-induced catatonia."3.67GABAergic, dopaminergic and cholinergic interactions in perphenazine-induced catatonia in rats. ( Garg, SK; Kulkarni, SK; Mathur, VS; Shukla, VK, 1985)
"In DSM-5, catatonia syndrome may be diagnosed as a specifier to major mood disorders, psychotic disorders, general medical conditions, and as catatonia not otherwise specified."2.53Catatonia. ( Strik, W; Walther, S, 2016)
"Catatonia is potentially life threatening."2.53Catatonia. ( Strik, W; Walther, S, 2016)
"The blueprint for the future study of catatonia in ASDs describes promising clinical and preclinical research avenues."2.43Blueprints for the assessment, treatment, and future study of catatonia in autism spectrum disorders. ( Dhossche, DM; Shah, A; Wing, L, 2006)
"Modern classificatory schemes define autism and catatonia separately and are not conducive to study areas of overlap."2.42Autism as early expression of catatonia. ( Dhossche, DM, 2004)
"The literature on autism and catatonia are reviewed to identify areas of overlap."2.42Autism as early expression of catatonia. ( Dhossche, DM, 2004)
"Several areas of overlap between autism and catatonia are found."2.42Autism as early expression of catatonia. ( Dhossche, DM, 2004)
"Reports indicate that catatonia often occurs in autism."2.42Autism as early expression of catatonia. ( Dhossche, DM, 2004)
"Differences between autism and catatonia of age-of-onset, symptoms, and illness course, do not exclude a common genetic etiology."2.42Autism as early expression of catatonia. ( Dhossche, DM, 2004)
"Catatonia is a motor syndrome with abnormalities in neuroendocrine regulation."1.31Catatonia and ECT: Meduna's biological antagonism hypothesis reconsidered. ( Fink, M, 2002)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19905 (29.41)18.7374
1990's0 (0.00)18.2507
2000's6 (35.29)29.6817
2010's3 (17.65)24.3611
2020's3 (17.65)2.80

Authors

AuthorsStudies
Hirjak, D2
Wolf, RC2
Northoff, G2
Gouse, BM1
Spears, WE1
Nieves Archibald, A1
Montalvo, C1
Cooper, JJ1
Ross, DA1
Taylor, SF1
Plevin, D1
Mohan, T1
Bastiampillai, T1
Walther, S1
Strik, W1
Fink, M1
SIEROSLAWSKA, J1
Dhossche, DM4
Jibiki, T1
Song, Y1
Liu, Y1
Rout, U1
Shah, A1
Wing, L1
Izumi, K1
Munekata, E1
Yamamoto, H1
Yoshida, M1
Nakanishi, T1
Wong, P1
Barbeau, A1
Di Chiara, G1
Morelli, M1
Porceddu, ML1
Gessa, GL1
Lipcsey, A1
Kardos, J1
Prinz, G1
Simonyi, M1
Shukla, VK1
Garg, SK1
Mathur, VS1
Kulkarni, SK1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Use of Electroconvulsive Therapy to Treat Self-Injurious Behavior in Adults With Autism Spectrum Disorders[NCT03980366]1 participants (Actual)Interventional2019-03-15Terminated (stopped due to We have not obtained additional subjects and chose to terminate/close this study.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for gamma-aminobutyric acid and Catatonia

ArticleYear
Catatonia.
    CNS spectrums, 2016, Volume: 21, Issue:4

    Topics: Benzodiazepines; Catatonia; Diagnostic and Statistical Manual of Mental Disorders; Electroconvulsive

2016
Autism as early expression of catatonia.
    Medical science monitor : international medical journal of experimental and clinical research, 2004, Volume: 10, Issue:3

    Topics: Adolescent; Age of Onset; Autistic Disorder; Catatonia; Cerebellum; Child; gamma-Aminobutyric Acid;

2004
[Malignant catatonia and late-onset catatonia].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2004, Volume: 106, Issue:2

    Topics: Adult; Aged; Catatonia; Cerebral Cortex; Corpus Striatum; Dopamine; Electroconvulsive Therapy; Femal

2004
Is there a connection between autism, Prader-Willi syndrome, catatonia, and GABA?
    International review of neurobiology, 2005, Volume: 71

    Topics: Animals; Autistic Disorder; Catatonia; gamma-Aminobutyric Acid; Genetic Markers; Humans; Prader-Will

2005
Are autistic and catatonic regression related? A few working hypotheses involving gaba, Purkinje cell survival, neurogenesis, and ECT.
    International review of neurobiology, 2006, Volume: 72

    Topics: Adolescent; Animals; Autistic Disorder; Catatonia; Cell Survival; Child; Electroconvulsive Therapy;

2006
Blueprints for the assessment, treatment, and future study of catatonia in autism spectrum disorders.
    International review of neurobiology, 2006, Volume: 72

    Topics: Adult; Animals; Autistic Disorder; Catatonia; Central Nervous System Agents; Child; Electroconvulsiv

2006

Other Studies

11 other studies available for gamma-aminobutyric acid and Catatonia

ArticleYear
GABA and Negative Affect-Catatonia as Model of RDoC-Based Investigation in Psychiatry.
    Schizophrenia bulletin, 2019, 10-24, Volume: 45, Issue:6

    Topics: Affect; Catatonia; gamma-Aminobutyric Acid; Humans; Mental Disorders; Psychiatry

2019
Catatonia in a hospitalized patient with COVID-19 and proposed immune-mediated mechanism.
    Brain, behavior, and immunity, 2020, Volume: 89

    Topics: Aged; Atrial Fibrillation; Basal Ganglia; Betacoronavirus; C-Reactive Protein; Catatonia; Coronaviru

2020
COVID-19 Catatonia-Would We Even Know?
    Biological psychiatry, 2020, 09-01, Volume: 88, Issue:5

    Topics: Akinetic Mutism; Basal Ganglia; Benzodiazepines; Betacoronavirus; Catatonia; Coronavirus Infections;

2020
GABA
    Molecular psychiatry, 2021, Volume: 26, Issue:7

    Topics: Antipsychotic Agents; Catatonia; Clozapine; gamma-Aminobutyric Acid; Humans; Receptors, GABA-B

2021
The role of the GABAergic system in catatonia-Insights from clozapine and benzodiazepines.
    Asian journal of psychiatry, 2018, Volume: 32

    Topics: Antipsychotic Agents; Benzodiazepines; Catatonia; Clozapine; GABAergic Neurons; gamma-Aminobutyric A

2018
Catatonia and ECT: Meduna's biological antagonism hypothesis reconsidered.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2002, Volume: 3, Issue:2

    Topics: Amobarbital; Brain; Catatonia; Electroconvulsive Therapy; gamma-Aminobutyric Acid; Humans; Hypnotics

2002
PHARMACOLOGIC PROPERTIES OF GAMMA-AMINOBUTYRIC ACID AND ITS DERIVATIVES. II. EFFECT ON THE CENTRAL AND PERIPHERAL NERVOUS SYSTEM.
    Archivum immunologiae et therapiae experimentalis, 1965, Volume: 13

    Topics: Aminobutyrates; Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Behavior, Animal; Birds

1965
Central neuropharmacology of D-Ala2-Met-enkephalinamide and its interactions with taurine in rats.
    Advances in experimental medicine and biology, 1981, Volume: 139

    Topics: Analgesia; Animals; Catatonia; Corpus Striatum; Dopamine; Endorphins; Enkephalin, Methionine; Enkeph

1981
Evidence that nigral GABA mediates behavioural responses elicited by striatal dopamine receptor stimulation.
    Life sciences, 1978, Nov-13, Volume: 23, Issue:20

    Topics: Animals; Apomorphine; Behavior, Animal; Bicuculline; Catatonia; Corpus Striatum; Drug Interactions;

1978
[Effect of electroconvulsive therapy on the GABA level in the cerebrospinal fluid].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1986, Volume: 38, Issue:9

    Topics: Adult; Catatonia; Combined Modality Therapy; Electroconvulsive Therapy; Female; gamma-Aminobutyric A

1986
GABAergic, dopaminergic and cholinergic interactions in perphenazine-induced catatonia in rats.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 278, Issue:2

    Topics: Animals; Bromocriptine; Catatonia; Dopamine; Drug Synergism; GABA Antagonists; gamma-Aminobutyric Ac

1985