Page last updated: 2024-10-16

gamma-aminobutyric acid and Carpal Tunnel Syndrome

gamma-aminobutyric acid has been researched along with Carpal Tunnel Syndrome in 4 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Carpal Tunnel Syndrome: Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45)

Research Excerpts

ExcerptRelevanceReference
"Based on its efficacy in treating neuropathic pain, gabapentin may be effective for the treatment of carpal tunnel syndrome (CTS)."9.15Gabapentin for the treatment of carpal tunnel syndrome: a randomized controlled trial. ( Hui, AC; Leung, HW; Man, BL; Wong, LK; Wong, SM; Yu, E, 2011)
"To evaluate the analgesic efficacy and safety of gabapentin in the treatment of carpal tunnel syndrome (CTS), as well as the electromyographic (EMG) evolution after 6 months."7.74[Efficacy of gabapentin in the treatment of carpal tunnel syndrome]. ( Benito, P; Calvet, J; Castro, S; Docampo, E; Lisbona, MP; Segalés, N; Taverner, D, 2008)
"Gabapentin did not produce a significant reduction in symptom severity compared with placebo over an eight-week period."6.76Gabapentin for the treatment of carpal tunnel syndrome: a randomized controlled trial. ( Hui, AC; Leung, HW; Man, BL; Wong, LK; Wong, SM; Yu, E, 2011)
"Based on its efficacy in treating neuropathic pain, gabapentin may be effective for the treatment of carpal tunnel syndrome (CTS)."5.15Gabapentin for the treatment of carpal tunnel syndrome: a randomized controlled trial. ( Hui, AC; Leung, HW; Man, BL; Wong, LK; Wong, SM; Yu, E, 2011)
"To evaluate the analgesic efficacy and safety of gabapentin in the treatment of carpal tunnel syndrome (CTS), as well as the electromyographic (EMG) evolution after 6 months."3.74[Efficacy of gabapentin in the treatment of carpal tunnel syndrome]. ( Benito, P; Calvet, J; Castro, S; Docampo, E; Lisbona, MP; Segalés, N; Taverner, D, 2008)
"Gabapentin did not produce a significant reduction in symptom severity compared with placebo over an eight-week period."2.76Gabapentin for the treatment of carpal tunnel syndrome: a randomized controlled trial. ( Hui, AC; Leung, HW; Man, BL; Wong, LK; Wong, SM; Yu, E, 2011)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duman, I1
Aydemir, K1
Ozgul, A1
Kalyon, TA1
Hui, AC1
Wong, SM1
Leung, HW1
Man, BL1
Yu, E1
Wong, LK1
Ackerman, WE1
Ahmad, M1
Taverner, D1
Lisbona, MP1
Segalés, N1
Docampo, E1
Calvet, J1
Castro, S1
Benito, P1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pain Reduction and Changes in Upper Limb Function Produced by Physiotherapy, Ibuprofen Arginine, Gabapentin and the Absence of Treatment, in Carpal Tunnel Syndrome[NCT04025203]Phase 480 participants (Anticipated)Interventional2019-08-01Recruiting
Oral Gabapentin Versus Control in the Treatment of Carpal Tunnel Syndrome[NCT04285281]Phase 450 participants (Anticipated)Interventional2020-03-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for gamma-aminobutyric acid and Carpal Tunnel Syndrome

ArticleYear
Assessment of the efficacy of gabapentin in carpal tunnel syndrome.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2008, Volume: 14, Issue:3

    Topics: Adult; Amines; Analgesics; Carpal Tunnel Syndrome; Cyclohexanecarboxylic Acids; Female; Gabapentin;

2008
Gabapentin for the treatment of carpal tunnel syndrome: a randomized controlled trial.
    European journal of neurology, 2011, Volume: 18, Issue:5

    Topics: Adult; Amines; Analgesics; Carpal Tunnel Syndrome; Cyclohexanecarboxylic Acids; Double-Blind Method;

2011

Other Studies

2 other studies available for gamma-aminobutyric acid and Carpal Tunnel Syndrome

ArticleYear
Recurrent postoperative CRPS I in patients with abnormal preoperative sympathetic function.
    The Journal of hand surgery, 2008, Volume: 33, Issue:2

    Topics: Adult; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Autonomic Nerve Block; Carpal Tu

2008
[Efficacy of gabapentin in the treatment of carpal tunnel syndrome].
    Medicina clinica, 2008, Mar-22, Volume: 130, Issue:10

    Topics: Amines; Analgesics; Carpal Tunnel Syndrome; Cyclohexanecarboxylic Acids; Electromyography; Female; G

2008
[Efficacy of gabapentin in the treatment of carpal tunnel syndrome].
    Medicina clinica, 2008, Mar-22, Volume: 130, Issue:10

    Topics: Amines; Analgesics; Carpal Tunnel Syndrome; Cyclohexanecarboxylic Acids; Electromyography; Female; G

2008
[Efficacy of gabapentin in the treatment of carpal tunnel syndrome].
    Medicina clinica, 2008, Mar-22, Volume: 130, Issue:10

    Topics: Amines; Analgesics; Carpal Tunnel Syndrome; Cyclohexanecarboxylic Acids; Electromyography; Female; G

2008
[Efficacy of gabapentin in the treatment of carpal tunnel syndrome].
    Medicina clinica, 2008, Mar-22, Volume: 130, Issue:10

    Topics: Amines; Analgesics; Carpal Tunnel Syndrome; Cyclohexanecarboxylic Acids; Electromyography; Female; G

2008