gamma-aminobutyric acid has been researched along with Carpal Tunnel Syndrome in 4 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Carpal Tunnel Syndrome: Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Based on its efficacy in treating neuropathic pain, gabapentin may be effective for the treatment of carpal tunnel syndrome (CTS)." | 9.15 | Gabapentin for the treatment of carpal tunnel syndrome: a randomized controlled trial. ( Hui, AC; Leung, HW; Man, BL; Wong, LK; Wong, SM; Yu, E, 2011) |
| "To evaluate the analgesic efficacy and safety of gabapentin in the treatment of carpal tunnel syndrome (CTS), as well as the electromyographic (EMG) evolution after 6 months." | 7.74 | [Efficacy of gabapentin in the treatment of carpal tunnel syndrome]. ( Benito, P; Calvet, J; Castro, S; Docampo, E; Lisbona, MP; Segalés, N; Taverner, D, 2008) |
| "Gabapentin did not produce a significant reduction in symptom severity compared with placebo over an eight-week period." | 6.76 | Gabapentin for the treatment of carpal tunnel syndrome: a randomized controlled trial. ( Hui, AC; Leung, HW; Man, BL; Wong, LK; Wong, SM; Yu, E, 2011) |
| "Based on its efficacy in treating neuropathic pain, gabapentin may be effective for the treatment of carpal tunnel syndrome (CTS)." | 5.15 | Gabapentin for the treatment of carpal tunnel syndrome: a randomized controlled trial. ( Hui, AC; Leung, HW; Man, BL; Wong, LK; Wong, SM; Yu, E, 2011) |
| "To evaluate the analgesic efficacy and safety of gabapentin in the treatment of carpal tunnel syndrome (CTS), as well as the electromyographic (EMG) evolution after 6 months." | 3.74 | [Efficacy of gabapentin in the treatment of carpal tunnel syndrome]. ( Benito, P; Calvet, J; Castro, S; Docampo, E; Lisbona, MP; Segalés, N; Taverner, D, 2008) |
| "Gabapentin did not produce a significant reduction in symptom severity compared with placebo over an eight-week period." | 2.76 | Gabapentin for the treatment of carpal tunnel syndrome: a randomized controlled trial. ( Hui, AC; Leung, HW; Man, BL; Wong, LK; Wong, SM; Yu, E, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duman, I | 1 |
| Aydemir, K | 1 |
| Ozgul, A | 1 |
| Kalyon, TA | 1 |
| Hui, AC | 1 |
| Wong, SM | 1 |
| Leung, HW | 1 |
| Man, BL | 1 |
| Yu, E | 1 |
| Wong, LK | 1 |
| Ackerman, WE | 1 |
| Ahmad, M | 1 |
| Taverner, D | 1 |
| Lisbona, MP | 1 |
| Segalés, N | 1 |
| Docampo, E | 1 |
| Calvet, J | 1 |
| Castro, S | 1 |
| Benito, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pain Reduction and Changes in Upper Limb Function Produced by Physiotherapy, Ibuprofen Arginine, Gabapentin and the Absence of Treatment, in Carpal Tunnel Syndrome[NCT04025203] | Phase 4 | 80 participants (Anticipated) | Interventional | 2019-08-01 | Recruiting | ||
| Oral Gabapentin Versus Control in the Treatment of Carpal Tunnel Syndrome[NCT04285281] | Phase 4 | 50 participants (Anticipated) | Interventional | 2020-03-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for gamma-aminobutyric acid and Carpal Tunnel Syndrome
| Article | Year |
|---|---|
Assessment of the efficacy of gabapentin in carpal tunnel syndrome.
Topics: Adult; Amines; Analgesics; Carpal Tunnel Syndrome; Cyclohexanecarboxylic Acids; Female; Gabapentin; | 2008 |
Gabapentin for the treatment of carpal tunnel syndrome: a randomized controlled trial.
Topics: Adult; Amines; Analgesics; Carpal Tunnel Syndrome; Cyclohexanecarboxylic Acids; Double-Blind Method; | 2011 |
2 other studies available for gamma-aminobutyric acid and Carpal Tunnel Syndrome
| Article | Year |
|---|---|
Recurrent postoperative CRPS I in patients with abnormal preoperative sympathetic function.
Topics: Adult; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Autonomic Nerve Block; Carpal Tu | 2008 |
[Efficacy of gabapentin in the treatment of carpal tunnel syndrome].
Topics: Amines; Analgesics; Carpal Tunnel Syndrome; Cyclohexanecarboxylic Acids; Electromyography; Female; G | 2008 |
[Efficacy of gabapentin in the treatment of carpal tunnel syndrome].
Topics: Amines; Analgesics; Carpal Tunnel Syndrome; Cyclohexanecarboxylic Acids; Electromyography; Female; G | 2008 |
[Efficacy of gabapentin in the treatment of carpal tunnel syndrome].
Topics: Amines; Analgesics; Carpal Tunnel Syndrome; Cyclohexanecarboxylic Acids; Electromyography; Female; G | 2008 |
[Efficacy of gabapentin in the treatment of carpal tunnel syndrome].
Topics: Amines; Analgesics; Carpal Tunnel Syndrome; Cyclohexanecarboxylic Acids; Electromyography; Female; G | 2008 |