Page last updated: 2024-10-16

gamma-aminobutyric acid and Cardiovascular Stroke

gamma-aminobutyric acid has been researched along with Cardiovascular Stroke in 12 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Research Excerpts

ExcerptRelevanceReference
"In patients with diabetic neuropathy who were prescribed gabapentin and pregabalin, there is an increased risk for heart failure, myocardial infarction, peripheral vascular disease, stroke, deep venous thrombosis, and pulmonary embolism with long-term use."4.12Cardiovascular risk of gabapentin and pregabalin in patients with diabetic neuropathy. ( Blankfield, RP; Davis, PB; Kaebler, DC; Pan, Y; Xu, R, 2022)
"Gabapentin and pregabalin are commonly prescribed medications to treat pain in patients with diabetic neuropathy."4.12Cardiovascular risk of gabapentin and pregabalin in patients with diabetic neuropathy. ( Blankfield, RP; Davis, PB; Kaebler, DC; Pan, Y; Xu, R, 2022)
"The effect of nimodipine, mexidol, melatonin, afobazole, 5-hydroxy-adanamtan-2-one, and GABA conjugates with arachidonic acid and docosahexaenoyl dopamine on the cerebral circulation has been studied in intact rats and those with global transient cerebral ischemia, experimental myocardial infarction, and combined vascular pathology of brain and heart."3.80[Cerebrovascular pharmacology of separate and combined vascular pathology of brain and heart]. ( Gan'shina, TS; Gnezdilova, AV; Gorbunov, AA; Khaĭlov, NA; Kurdiumov, IN; Lebedeva, MA; Maslennikov, DV; Mirzoian, RS, 2014)
" However, whether long-term use of gabapentin and pregabalin is associated with adverse cardiovascular diseases remains unknown."1.72Cardiovascular risk of gabapentin and pregabalin in patients with diabetic neuropathy. ( Blankfield, RP; Davis, PB; Kaebler, DC; Pan, Y; Xu, R, 2022)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's1 (8.33)18.2507
2000's0 (0.00)29.6817
2010's6 (50.00)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Pan, Y1
Davis, PB1
Kaebler, DC1
Blankfield, RP1
Xu, R1
Gao, M1
Yin, D1
Chen, J1
Qu, X1
Mirzoian, RS1
Gan'shina, TS1
Khaĭlov, NA1
Gnezdilova, AV1
Maslennikov, DV1
Kurdiumov, IN1
Lebedeva, MA1
Gorbunov, AA1
Liepinsh, E2
Makrecka-Kuka, M2
Kuka, J2
Vilskersts, R1
Makarova, E1
Cirule, H2
Loza, E1
Lola, D1
Grinberga, S2
Pugovics, O1
Kalvins, I1
Dambrova, M2
Li, J1
Zhang, MM1
Tu, K1
Wang, J1
Feng, B1
Zhang, ZN1
Lei, J1
Li, YQ1
Du, JQ1
Chen, T1
Pandit, S1
Jo, JY1
Lee, SU1
Lee, YJ1
Lee, SY2
Ryu, PD2
Lee, JU1
Kim, HW1
Jeon, BH1
Park, JB1
Sevostjanovs, E1
Lee, CH1
Hwang, IK1
Choi, JH1
Yoo, KY1
Han, TH1
Park, OK1
Won, MH1
Meerson, FZ2
Pavlova, VI1
Iakushev, VS1
Sinitsyn, SP1
Galenko-Iaroshevskiĭ, PA1
Medvedev, OS1
Uvarov, AV1
Mingalev, AN1
Turovaia, AIu1
Tiukhteneva, ZI1
Abdikaliev, NA1
Shabunina, EV1
Sidhu, HS1
Munoz, DG1
Wood, JD1

Other Studies

12 other studies available for gamma-aminobutyric acid and Cardiovascular Stroke

ArticleYear
Cardiovascular risk of gabapentin and pregabalin in patients with diabetic neuropathy.
    Cardiovascular diabetology, 2022, 09-01, Volume: 21, Issue:1

    Topics: Amines; Analgesics; Cardiovascular Diseases; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gab

2022
Activating the interleukin-6-Gp130-STAT3 pathway ameliorates ventricular electrical stability in myocardial infarction rats by modulating neurotransmitters in the paraventricular nucleus.
    BMC cardiovascular disorders, 2020, 02-05, Volume: 20, Issue:1

    Topics: Action Potentials; Animals; Cytokine Receptor gp130; Disease Models, Animal; gamma-Aminobutyric Acid

2020
[Cerebrovascular pharmacology of separate and combined vascular pathology of brain and heart].
    Eksperimental'naia i klinicheskaia farmakologiia, 2014, Volume: 77, Issue:3

    Topics: Adamantane; Animals; Animals, Outbred Strains; Benzimidazoles; Bicuculline; Cerebral Cortex; Dopamin

2014
Inhibition of L-carnitine biosynthesis and transport by methyl-γ-butyrobetaine decreases fatty acid oxidation and protects against myocardial infarction.
    British journal of pharmacology, 2015, Volume: 172, Issue:5

    Topics: Animals; Biological Transport; Carnitine; Dose-Response Relationship, Drug; Fatty Acids; gamma-Amino

2015
The excitatory synaptic transmission of the nucleus of solitary tract was potentiated by chronic myocardial infarction in rats.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Excitatory Postsyn

2015
Enhanced astroglial GABA uptake attenuates tonic GABAA inhibition of the presympathetic hypothalamic paraventricular nucleus neurons in heart failure.
    Journal of neurophysiology, 2015, Volume: 114, Issue:2

    Topics: Action Potentials; Animals; Astrocytes; Disease Models, Animal; GABA Plasma Membrane Transport Prote

2015
Decrease in Long-Chain Acylcarnitine Tissue Content Determines the Duration of and Correlates with the Cardioprotective Effect of Methyl-GBB.
    Basic & clinical pharmacology & toxicology, 2017, Volume: 121, Issue:2

    Topics: Animals; Betaine; Biotransformation; Cardiotonic Agents; Carnitine; Down-Regulation; gamma-Aminobuty

2017
Calcium binding proteins immunoreactivity in the rat basolateral amygdala following myocardial infarction.
    Cellular and molecular neurobiology, 2010, Volume: 30, Issue:3

    Topics: Amygdala; Animals; Biomarkers; Brain Mapping; Calbindin 2; Calbindins; Calcium-Binding Proteins; Dep

2010
[Activation of GABA system metabolism in the cerebral hemispheres during exposure to different stress factors].
    Biulleten' eksperimental'noi biologii i meditsiny, 1981, Volume: 91, Issue:1

    Topics: 4-Aminobutyrate Transaminase; Animals; Aortic Valve Stenosis; Brain; Brain Chemistry; Formaldehyde;

1981
[Effect of the gamma-aminobutyric acid derivative, TZ-50-2, on the systemic and cardiac hemodynamics, and the size of myocardial necrosis area].
    Biulleten' eksperimental'noi biologii i meditsiny, 1998, Volume: 126, Issue:12

    Topics: Animals; Anti-Arrhythmia Agents; Cats; Coronary Circulation; GABA Agonists; gamma-Aminobutyric Acid;

1998
[Elimination of disorders in the electrical stability of the heart during postinfarct cardiosclerosis by using a factor that induces GABA accumulation in the brain].
    Biulleten' eksperimental'noi biologii i meditsiny, 1989, Volume: 107, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Brain; Drug Evaluation, Preclinical; Electroc

1989
gamma-Aminobutyric acid (GABA) uptake systems in human frontal cortex.
    Brain research, 1987, Dec-01, Volume: 435, Issue:1-2

    Topics: Aged; Animals; Biological Transport; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Humans; Kinet

1987