gamma-aminobutyric acid has been researched along with Cancer of the Thyroid in 2 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The formation of different metabolites from 14C-putrescine via oxidative deamination has been studied in patients with medullary carcinoma of the thyroid (MCT) and in control subjects." | 7.66 | Diamine oxidase activity and gamma-aminobutyric acid formation in medullary carcinoma of the thyroid. ( Andersson, AC; Henningsson, S; Järhult, J, 1980) |
| "The formation of different metabolites from 14C-putrescine via oxidative deamination has been studied in patients with medullary carcinoma of the thyroid (MCT) and in control subjects." | 3.66 | Diamine oxidase activity and gamma-aminobutyric acid formation in medullary carcinoma of the thyroid. ( Andersson, AC; Henningsson, S; Järhult, J, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, SY | 1 |
| Jeong, JJ | 1 |
| Chung, WY | 1 |
| Kim, HJ | 1 |
| Nam, KH | 1 |
| Shim, YH | 1 |
| Andersson, AC | 1 |
| Henningsson, S | 1 |
| Järhult, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Use of Single Dose Pre-Operative Pregabalin for Post-Operative Analgesia in Bilateral Head and Neck Cancer Surgery: A Randomized, Double-Blinded, Placebo-Controlled Trial[NCT03714867] | Phase 4 | 0 participants (Actual) | Interventional | 2019-03-22 | Withdrawn (stopped due to Inability to recruit patients) | ||
| Perioperative Administration of Pregabalin for Pain After Robot-assisted Endoscopic Thyroidectomy[NCT00905580] | Phase 4 | 99 participants (Actual) | Interventional | 2009-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
we checked Hypoesthesia in the anterior chest at 3 months after operation by phone. (NCT00905580)
Timeframe: 3 months
| Intervention | participants (Number) |
|---|---|
| Placebo | 13 |
| Pregabalin | 10 |
(NCT00905580)
Timeframe: 1, 6, 24 & 48 hours
| Intervention | participants (Number) | |||
|---|---|---|---|---|
| 0-1 hour | 1-6 hour | 6 - 24 hour | 24 - 48 hour | |
| Placebo | 31 | 17 | 15 | 7 |
| Pregabalin | 26 | 7 | 2 | 1 |
Pain was evaluated using an 11-point verbal numerical rating scale (VNRS). Patients were instructed preoperatively to express their pain on the 0-10 VNRS, where 0 means no pain at all, and 10 represents the worst pain imaginable (NCT00905580)
Timeframe: 1, 6, 24 & 48 hours
| Intervention | VNRS (Median) | |||
|---|---|---|---|---|
| 1 Hour | 6 Hour | 24 Hour | 48 Hour | |
| Placebo | 6 | 3 | 2 | 2 |
| Pregabalin | 6 | 2 | 1 | 1 |
Nausea and vomiting was graded on a four-point scale, where 0 = no nausea, 1 = mild nausea, 2 = severe nausea requiring antiemetics, and 3 = retching and/ or vomiting. Grades 3 and 4 were grouped together as postoperative nausea and vomiting (PONV) and rescue anti-emetic, metoclopramide 10 mg i.v. was given. We asked patients about sedation, headache, dizziness, blurred vision. (NCT00905580)
Timeframe: 1, 6, 24 & 48 hours
| Intervention | participants (Number) | ||||
|---|---|---|---|---|---|
| PONV | headache | dizziness | sedation | blurred vision | |
| Placebo | 10 | 11 | 6 | 1 | 0 |
| Pregabalin | 7 | 8 | 14 | 6 | 3 |
1 trial available for gamma-aminobutyric acid and Cancer of the Thyroid
| Article | Year |
|---|---|
Perioperative administration of pregabalin for pain after robot-assisted endoscopic thyroidectomy: a randomized clinical trial.
Topics: Administration, Oral; Adult; Analgesics; Double-Blind Method; Endoscopy; Female; gamma-Aminobutyric | 2010 |
Perioperative administration of pregabalin for pain after robot-assisted endoscopic thyroidectomy: a randomized clinical trial.
Topics: Administration, Oral; Adult; Analgesics; Double-Blind Method; Endoscopy; Female; gamma-Aminobutyric | 2010 |
Perioperative administration of pregabalin for pain after robot-assisted endoscopic thyroidectomy: a randomized clinical trial.
Topics: Administration, Oral; Adult; Analgesics; Double-Blind Method; Endoscopy; Female; gamma-Aminobutyric | 2010 |
Perioperative administration of pregabalin for pain after robot-assisted endoscopic thyroidectomy: a randomized clinical trial.
Topics: Administration, Oral; Adult; Analgesics; Double-Blind Method; Endoscopy; Female; gamma-Aminobutyric | 2010 |
1 other study available for gamma-aminobutyric acid and Cancer of the Thyroid
| Article | Year |
|---|---|
Diamine oxidase activity and gamma-aminobutyric acid formation in medullary carcinoma of the thyroid.
Topics: Adult; Amine Oxidase (Copper-Containing); Carcinoma; Female; gamma-Aminobutyric Acid; Humans; Male; | 1980 |